Rattus norvegicus

0 known processes

Casp4

caspase 4, apoptosis-related cysteine peptidase

(Aliases: Casp11,MGC124949)

Casp4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 226 0.101
response to inorganic substance GO:0010035 377 0.097
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.094
response to metal ion GO:0010038 253 0.075
peptide biosynthetic process GO:0043043 3 0.075
immune response GO:0006955 104 0.070
protein oligomerization GO:0051259 191 0.065
immune system process GO:0002376 204 0.063
response to bacterium GO:0009617 200 0.060
response to molecule of bacterial origin GO:0002237 194 0.059
reproductive process GO:0022414 372 0.048
amide biosynthetic process GO:0043604 10 0.046
multi organism reproductive process GO:0044703 262 0.046
response to transition metal nanoparticle GO:1990267 122 0.045
regulation of interleukin 1 beta secretion GO:0050706 3 0.044
regulation of cellular localization GO:0060341 263 0.042
protein complex assembly GO:0006461 263 0.042
secretion GO:0046903 307 0.041
neuron development GO:0048666 286 0.039
positive regulation of programmed cell death GO:0043068 157 0.038
positive regulation of apoptotic process GO:0043065 154 0.038
protein transport GO:0015031 132 0.038
response to acid chemical GO:0001101 222 0.038
regulation of apoptotic process GO:0042981 335 0.038
positive regulation of immune system process GO:0002684 90 0.037
positive regulation of cell death GO:0010942 184 0.037
cellular catabolic process GO:0044248 295 0.037
response to anoxia GO:0034059 4 0.037
neuron differentiation GO:0030182 368 0.037
interleukin 1 beta secretion GO:0050702 3 0.035
response to other organism GO:0051707 220 0.035
protein complex subunit organization GO:0071822 302 0.035
positive regulation of developmental process GO:0051094 283 0.035
positive regulation of transport GO:0051050 245 0.034
organonitrogen compound biosynthetic process GO:1901566 167 0.034
response to lipopolysaccharide GO:0032496 191 0.033
regulation of cytokine production GO:0001817 56 0.033
macromolecular complex subunit organization GO:0043933 339 0.032
response to oxidative stress GO:0006979 186 0.032
regulation of immune system process GO:0002682 123 0.032
acute inflammatory response to non antigenic stimulus GO:0002525 2 0.032
response to cytokine GO:0034097 215 0.032
regulation of interleukin 1 secretion GO:0050704 3 0.031
rna metabolic process GO:0016070 406 0.031
macromolecular complex assembly GO:0065003 273 0.031
establishment of protein localization GO:0045184 141 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
response to external biotic stimulus GO:0043207 221 0.030
interleukin 1 secretion GO:0050701 3 0.030
positive regulation of molecular function GO:0044093 230 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
response to radiation GO:0009314 137 0.029
intracellular signal transduction GO:0035556 314 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
secretion by cell GO:0032940 248 0.029
activation of cysteine type endopeptidase activity GO:0097202 4 0.029
proteolysis GO:0006508 175 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
microglial cell activation GO:0001774 14 0.027
central nervous system development GO:0007417 311 0.027
regulation of cell differentiation GO:0045595 320 0.027
regulation of secretion GO:0051046 224 0.026
regulation of membrane potential GO:0042391 110 0.026
lens development in camera type eye GO:0002088 13 0.025
regulation of programmed cell death GO:0043067 341 0.025
reproduction GO:0000003 245 0.025
multicellular organism reproduction GO:0032504 233 0.024
cytokine production GO:0001816 61 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
nucleotide metabolic process GO:0009117 279 0.024
regulation of molecular function GO:0065009 398 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
regulation of cellular component organization GO:0051128 368 0.023
positive regulation of secretion GO:0051047 140 0.023
macromolecule localization GO:0033036 252 0.023
response to oxygen levels GO:0070482 265 0.023
cell type specific apoptotic process GO:0097285 134 0.023
regulation of protein metabolic process GO:0051246 289 0.023
positive regulation of cell development GO:0010720 176 0.023
cellular response to stress GO:0033554 269 0.022
neuron projection development GO:0031175 273 0.022
chemical homeostasis GO:0048878 292 0.022
response to temperature stimulus GO:0009266 94 0.022
gonad development GO:0008406 104 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
development of primary sexual characteristics GO:0045137 107 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
cellular ketone metabolic process GO:0042180 51 0.021
cation homeostasis GO:0055080 195 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
multi multicellular organism process GO:0044706 138 0.020
positive regulation of humoral immune response GO:0002922 2 0.020
defense response GO:0006952 194 0.020
single organism reproductive process GO:0044702 297 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
head development GO:0060322 247 0.020
cellular component biogenesis GO:0044085 368 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
sex differentiation GO:0007548 113 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
response to hydrogen peroxide GO:0042542 89 0.019
negative regulation of metabolic process GO:0009892 331 0.019
catabolic process GO:0009056 351 0.019
regulation of retinal cell programmed cell death GO:0046668 1 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
cellular response to peptide GO:1901653 133 0.019
gamete generation GO:0007276 124 0.019
regulation of circadian sleep wake cycle GO:0042749 18 0.019
regulation of neuron death GO:1901214 115 0.019
tube development GO:0035295 89 0.019
protein phosphorylation GO:0006468 345 0.018
regulation of nervous system development GO:0051960 264 0.018
aging GO:0007568 241 0.018
protein complex biogenesis GO:0070271 263 0.018
regulation of protein localization GO:0032880 81 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
homeostatic process GO:0042592 331 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
cellular response to biotic stimulus GO:0071216 59 0.018
regulation of immune response GO:0050776 55 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
pallium development GO:0021543 42 0.018
retinal cell programmed cell death GO:0046666 1 0.018
anatomical structure morphogenesis GO:0009653 298 0.017
anion transport GO:0006820 178 0.017
cell activation GO:0001775 97 0.017
cellular component assembly GO:0022607 360 0.017
cellular amide metabolic process GO:0043603 44 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
cellular amine metabolic process GO:0044106 38 0.017
protein heterooligomerization GO:0051291 89 0.017
response to heat GO:0009408 60 0.017
regulation of rna metabolic process GO:0051252 391 0.017
brain development GO:0007420 247 0.017
leukocyte activation GO:0045321 76 0.017
peptide metabolic process GO:0006518 32 0.016
regulation of secretion by cell GO:1903530 208 0.016
amine metabolic process GO:0009308 38 0.016
male gamete generation GO:0048232 99 0.016
response to hypoxia GO:0001666 231 0.016
apoptotic process GO:0006915 381 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
positive regulation of immune response GO:0050778 42 0.016
response to toxic substance GO:0009636 133 0.016
response to glucose GO:0009749 136 0.015
syncytium formation by plasma membrane fusion GO:0000768 3 0.015
developmental process involved in reproduction GO:0003006 159 0.015
eye morphogenesis GO:0048592 4 0.015
regulation of transcription dna templated GO:0006355 374 0.015
programmed cell death GO:0012501 392 0.015
positive regulation of interleukin 1 secretion GO:0050716 3 0.015
response to reactive oxygen species GO:0000302 120 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
positive regulation of cytokine production GO:0001819 42 0.015
carboxylic acid metabolic process GO:0019752 289 0.015
telencephalon development GO:0021537 62 0.014
exocytosis GO:0006887 60 0.014
organic anion transport GO:0015711 132 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
response to decreased oxygen levels GO:0036293 237 0.014
response to amino acid GO:0043200 75 0.014
response to wounding GO:0009611 254 0.014
purine containing compound metabolic process GO:0072521 253 0.014
oxoacid metabolic process GO:0043436 290 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
regulation of innate immune response GO:0045088 15 0.014
response to extracellular stimulus GO:0009991 380 0.014
regulation of phosphorylation GO:0042325 248 0.014
regulation of response to stress GO:0080134 126 0.014
spermatogenesis GO:0007283 99 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
response to mechanical stimulus GO:0009612 134 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
regulation of response to wounding GO:1903034 69 0.013
organic acid metabolic process GO:0006082 292 0.013
rna biosynthetic process GO:0032774 380 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
positive regulation of behavior GO:0048520 38 0.013
programmed necrotic cell death GO:0097300 2 0.013
forebrain development GO:0030900 98 0.013
organophosphate metabolic process GO:0019637 370 0.013
response to carbohydrate GO:0009743 183 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
nitrogen compound transport GO:0071705 229 0.013
regulation of signal transduction GO:0009966 318 0.013
response to estradiol GO:0032355 164 0.013
rhythmic process GO:0048511 156 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.013
myeloid leukocyte activation GO:0002274 36 0.013
regulation of cell development GO:0060284 263 0.013
protein maturation GO:0051604 68 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
axis specification GO:0009798 4 0.013
response to estrogen GO:0043627 232 0.013
regulation of protein transport GO:0051223 68 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
sexual reproduction GO:0019953 148 0.013
single organism intracellular transport GO:1902582 166 0.013
regulation of defense response GO:0031347 68 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
axon development GO:0061564 96 0.012
response to ethanol GO:0045471 162 0.012
nucleoside metabolic process GO:0009116 179 0.012
positive regulation of retinal cell programmed cell death GO:0046670 1 0.012
response to alkaloid GO:0043279 132 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
neuron apoptotic process GO:0051402 88 0.012
organic substance catabolic process GO:1901575 316 0.012
regulation of neuron projection development GO:0010975 161 0.012
response to vitamin GO:0033273 131 0.012
intracellular transport GO:0046907 185 0.012
cellular chemical homeostasis GO:0055082 247 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
female sex differentiation GO:0046660 59 0.012
regulation of catalytic activity GO:0050790 304 0.012
regulation of cell proliferation GO:0042127 359 0.012
organic acid transport GO:0015849 116 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.012
ras protein signal transduction GO:0007265 29 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
protein localization GO:0008104 191 0.011
positive regulation of interleukin 1 beta production GO:0032731 6 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
blood vessel morphogenesis GO:0048514 58 0.011
regulation of neuron differentiation GO:0045664 208 0.011
response to ketone GO:1901654 182 0.011
positive regulation of protein transport GO:0051222 41 0.011
regulation of proteolysis GO:0030162 66 0.011
response to nutrient levels GO:0031667 370 0.011
cellular homeostasis GO:0019725 252 0.011
vasculature development GO:0001944 70 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
positive regulation of neuron death GO:1901216 43 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
stress activated protein kinase signaling cascade GO:0031098 37 0.011
syncytium formation GO:0006949 4 0.011
myoblast fusion GO:0007520 2 0.011
negative regulation of cell communication GO:0010648 158 0.011
negative regulation of gene expression GO:0010629 199 0.011
response to ionizing radiation GO:0010212 59 0.011
cellular component morphogenesis GO:0032989 155 0.011
regulation of phosphorus metabolic process GO:0051174 349 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
protein homooligomerization GO:0051260 91 0.010
ion homeostasis GO:0050801 212 0.010
glial cell apoptotic process GO:0034349 8 0.010
acute inflammatory response GO:0002526 58 0.010
response to hexose GO:0009746 144 0.010
cation transport GO:0006812 382 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
steroid metabolic process GO:0008202 73 0.010
negative regulation of signaling GO:0023057 157 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
ribonucleotide metabolic process GO:0009259 231 0.010

Casp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017