Rattus norvegicus

80 known processes

Acvr2a

activin A receptor, type IIA

(Aliases: rActR-II,Acvr2)

Acvr2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anatomical structure morphogenesis GO:0009653 298 0.202
Mouse
locomotion GO:0040011 237 0.120
Zebrafish
macromolecular complex subunit organization GO:0043933 339 0.117
transcription dna templated GO:0006351 377 0.116
Human Mouse
secretion GO:0046903 307 0.115
cellular component biogenesis GO:0044085 368 0.108
organelle organization GO:0006996 266 0.102
single organism organelle organization GO:1902589 180 0.101
rna metabolic process GO:0016070 406 0.093
Human Mouse
reproductive process GO:0022414 372 0.093
Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.092
Human Mouse
intracellular signal transduction GO:0035556 314 0.091
neuron differentiation GO:0030182 368 0.091
regulation of cell differentiation GO:0045595 320 0.090
Human
regulation of rna metabolic process GO:0051252 391 0.090
Human Mouse
rna biosynthetic process GO:0032774 380 0.090
Human Mouse
organic acid metabolic process GO:0006082 292 0.088
regulation of phosphorylation GO:0042325 248 0.087
Human
regulation of multicellular organismal development GO:2000026 376 0.084
Human
cellular component assembly GO:0022607 360 0.084
cell cell signaling GO:0007267 335 0.082
neuron development GO:0048666 286 0.080
localization of cell GO:0051674 202 0.080
Zebrafish
positive regulation of transport GO:0051050 245 0.075
cellular amino acid metabolic process GO:0006520 107 0.075
response to nutrient levels GO:0031667 370 0.072
multi organism reproductive process GO:0044703 262 0.071
Mouse
tissue development GO:0009888 252 0.071
Human Zebrafish Mouse
regulation of rna biosynthetic process GO:2001141 381 0.070
Human Mouse
single organism reproductive process GO:0044702 297 0.070
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.070
Human
positive regulation of cellular biosynthetic process GO:0031328 295 0.069
regulation of transcription dna templated GO:0006355 374 0.068
Human Mouse
central nervous system development GO:0007417 311 0.067
Zebrafish
programmed cell death GO:0012501 392 0.067
regulation of neurogenesis GO:0050767 247 0.066
response to estrogen GO:0043627 232 0.065
regulation of protein metabolic process GO:0051246 289 0.064
Human
regulation of cell development GO:0060284 263 0.063
carboxylic acid metabolic process GO:0019752 289 0.062
regulation of cellular localization GO:0060341 263 0.062
gland development GO:0048732 155 0.062
regulation of cellular component organization GO:0051128 368 0.062
synaptic transmission GO:0007268 235 0.061
cellular component movement GO:0006928 248 0.061
Zebrafish
cellular response to endogenous stimulus GO:0071495 377 0.061
Human
apoptotic process GO:0006915 381 0.060
regulation of phosphorus metabolic process GO:0051174 349 0.060
Human
cell projection organization GO:0030030 302 0.059
homeostatic process GO:0042592 331 0.058
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.058
brain development GO:0007420 247 0.057
Zebrafish
nucleic acid templated transcription GO:0097659 379 0.057
Human Mouse
positive regulation of response to stimulus GO:0048584 285 0.056
Human
circulatory system development GO:0072359 134 0.056
response to peptide GO:1901652 292 0.056
secretion by cell GO:0032940 248 0.056
positive regulation of molecular function GO:0044093 230 0.055
oxoacid metabolic process GO:0043436 290 0.054
regulation of signal transduction GO:0009966 318 0.054
Human Mouse
regulation of molecular function GO:0065009 398 0.054
Mouse
protein phosphorylation GO:0006468 345 0.054
regulation of nervous system development GO:0051960 264 0.054
positive regulation of biosynthetic process GO:0009891 319 0.054
sexual reproduction GO:0019953 148 0.054
Mouse
positive regulation of developmental process GO:0051094 283 0.053
Human
positive regulation of cell proliferation GO:0008284 249 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.050
multicellular organism reproduction GO:0032504 233 0.050
Mouse
regulation of apoptotic process GO:0042981 335 0.050
response to peptide hormone GO:0043434 278 0.049
enzyme linked receptor protein signaling pathway GO:0007167 116 0.048
cellular component morphogenesis GO:0032989 155 0.048
heart morphogenesis GO:0003007 3 0.047
aging GO:0007568 241 0.047
regulation of protein modification process GO:0031399 194 0.047
Human
positive regulation of gene expression GO:0010628 244 0.047
neurological system process GO:0050877 219 0.047
positive regulation of multicellular organismal process GO:0051240 387 0.046
positive regulation of signaling GO:0023056 270 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.046
response to extracellular stimulus GO:0009991 380 0.045
protein transport GO:0015031 132 0.045
response to estradiol GO:0032355 164 0.045
regulation of cellular protein metabolic process GO:0032268 267 0.044
Human
cell migration GO:0016477 197 0.044
Zebrafish
negative regulation of metabolic process GO:0009892 331 0.042
organophosphate metabolic process GO:0019637 370 0.042
multicellular organismal reproductive process GO:0048609 233 0.041
Mouse
single organism intracellular transport GO:1902582 166 0.041
regulation of anatomical structure morphogenesis GO:0022603 141 0.041
negative regulation of cell differentiation GO:0045596 99 0.041
rhythmic process GO:0048511 156 0.041
chemical homeostasis GO:0048878 292 0.040
catabolic process GO:0009056 351 0.040
cellular response to oxygen containing compound GO:1901701 386 0.040
regulation of cellular amine metabolic process GO:0033238 8 0.039
cellular response to hormone stimulus GO:0032870 247 0.039
mesoderm development GO:0007498 2 0.039
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.039
head development GO:0060322 247 0.038
Zebrafish
cytoskeleton organization GO:0007010 111 0.038
positive regulation of phosphate metabolic process GO:0045937 262 0.037
Human
cellular ketone metabolic process GO:0042180 51 0.037
regulation of programmed cell death GO:0043067 341 0.037
regulation of secretion by cell GO:1903530 208 0.037
negative regulation of transport GO:0051051 136 0.036
regulation of intracellular signal transduction GO:1902531 218 0.036
neuron projection development GO:0031175 273 0.036
transmembrane transport GO:0055085 412 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
organic substance catabolic process GO:1901575 316 0.036
regulation of neuron differentiation GO:0045664 208 0.035
macromolecule localization GO:0033036 252 0.035
actin filament based process GO:0030029 86 0.035
peptidyl amino acid modification GO:0018193 126 0.035
positive regulation of cell differentiation GO:0045597 217 0.035
Human
cellular response to stress GO:0033554 269 0.034
negative regulation of multicellular organismal process GO:0051241 203 0.034
response to growth factor GO:0070848 189 0.034
Human
regulation of protein localization GO:0032880 81 0.034
regulation of cell proliferation GO:0042127 359 0.034
transcription from rna polymerase ii promoter GO:0006366 252 0.034
Human Mouse
response to nutrient GO:0007584 248 0.034
cell motility GO:0048870 202 0.033
Zebrafish
blood vessel development GO:0001568 69 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.032
cellular amine metabolic process GO:0044106 38 0.032
small gtpase mediated signal transduction GO:0007264 36 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
Human
organ morphogenesis GO:0009887 75 0.032
synaptic growth at neuromuscular junction GO:0051124 1 0.031
cation transport GO:0006812 382 0.031
regulation of protein transport GO:0051223 68 0.031
regulation of protein phosphorylation GO:0001932 183 0.031
Human
protein localization GO:0008104 191 0.031
developmental process involved in reproduction GO:0003006 159 0.031
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 197 0.031
gastrulation GO:0007369 2 0.030
Mouse
regulation of response to stress GO:0080134 126 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.030
macromolecular complex assembly GO:0065003 273 0.030
g protein coupled receptor signaling pathway GO:0007186 242 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
negative regulation of gene expression GO:0010629 199 0.029
protein complex assembly GO:0006461 263 0.029
establishment of protein localization GO:0045184 141 0.029
amine metabolic process GO:0009308 38 0.028
positive regulation of cell communication GO:0010647 271 0.028
cellular catabolic process GO:0044248 295 0.028
cell cycle GO:0007049 101 0.028
response to oxygen levels GO:0070482 265 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
lipid metabolic process GO:0006629 283 0.028
neuron projection morphogenesis GO:0048812 122 0.028
negative regulation of response to stimulus GO:0048585 155 0.028
regulation of cellular catabolic process GO:0031329 101 0.028
biological adhesion GO:0022610 110 0.027
negative regulation of signaling GO:0023057 157 0.027
cardiovascular system development GO:0072358 134 0.027
regulation of hormone levels GO:0010817 187 0.027
positive regulation of cell death GO:0010942 184 0.027
cellular lipid metabolic process GO:0044255 208 0.027
response to inorganic substance GO:0010035 377 0.027
liver development GO:0001889 90 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
positive regulation of nervous system development GO:0051962 178 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
Human Mouse
organonitrogen compound biosynthetic process GO:1901566 167 0.027
response to ethanol GO:0045471 162 0.027
cellular chemical homeostasis GO:0055082 247 0.027
growth GO:0040007 165 0.026
regulation of cell cycle GO:0051726 73 0.026
reproduction GO:0000003 245 0.026
Mouse
positive regulation of rna biosynthetic process GO:1902680 197 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
hepaticobiliary system development GO:0061008 90 0.026
regulation of cellular component movement GO:0051270 150 0.026
peptidyl tyrosine phosphorylation GO:0018108 72 0.026
protein complex subunit organization GO:0071822 302 0.026
defense response GO:0006952 194 0.025
oxidation reduction process GO:0055114 304 0.025
Mouse
negative regulation of cell death GO:0060548 229 0.025
regulation of catalytic activity GO:0050790 304 0.025
Mouse
cellular response to organonitrogen compound GO:0071417 197 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
Human
response to glucocorticoid GO:0051384 223 0.024
regulation of transferase activity GO:0051338 123 0.024
regulation of cell motility GO:2000145 131 0.024
wound healing GO:0042060 122 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
response to hypoxia GO:0001666 231 0.024
negative regulation of cell communication GO:0010648 158 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
regulation of growth GO:0040008 105 0.024
protein oligomerization GO:0051259 191 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
neural crest cell development GO:0014032 2 0.024
Zebrafish
behavior GO:0007610 205 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
Human
intracellular transport GO:0046907 185 0.023
response to corticosteroid GO:0031960 235 0.023
cellular macromolecule localization GO:0070727 122 0.023
cell morphogenesis GO:0000902 142 0.023
cellular protein localization GO:0034613 122 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.023
Human
positive regulation of cell development GO:0010720 176 0.023
regulation of neuron projection development GO:0010975 161 0.023
purine containing compound metabolic process GO:0072521 253 0.023
cellular homeostasis GO:0019725 252 0.023
response to wounding GO:0009611 254 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.022
positive regulation of locomotion GO:0040017 102 0.022
nitrogen compound transport GO:0071705 229 0.022
response to external biotic stimulus GO:0043207 221 0.022
signal release GO:0023061 145 0.022
muscle structure development GO:0061061 87 0.022
positive regulation of cellular component movement GO:0051272 102 0.022
peptidyl tyrosine modification GO:0018212 72 0.022
protein complex biogenesis GO:0070271 263 0.022
positive regulation of neurogenesis GO:0050769 165 0.021
developmental growth GO:0048589 100 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
regulation of system process GO:0044057 208 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
cell adhesion GO:0007155 110 0.021
response to acid chemical GO:0001101 222 0.021
ras protein signal transduction GO:0007265 29 0.021
positive regulation of cell motility GO:2000147 97 0.021
regulation of catabolic process GO:0009894 113 0.021
ossification GO:0001503 70 0.021
Human
ion homeostasis GO:0050801 212 0.020
regulation of secretion GO:0051046 224 0.020
positive regulation of secretion GO:0051047 140 0.020
forebrain development GO:0030900 98 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
intracellular protein transport GO:0006886 79 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
Human
organonitrogen compound catabolic process GO:1901565 179 0.020
response to glucose GO:0009749 136 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
regulation of muscle system process GO:0090257 79 0.020
response to other organism GO:0051707 220 0.020
positive regulation of signal transduction GO:0009967 175 0.020
Human
ribose phosphate metabolic process GO:0019693 235 0.020
anatomical structure formation involved in morphogenesis GO:0048646 83 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
nucleotide metabolic process GO:0009117 279 0.020
endocytosis GO:0006897 84 0.019
response to oxidative stress GO:0006979 186 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.019
response to monosaccharide GO:0034284 159 0.019
regulation of establishment of protein localization GO:0070201 69 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
axis specification GO:0009798 4 0.019
regulation of proteasomal protein catabolic process GO:0061136 4 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
Human
gonad development GO:0008406 104 0.019
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.019
response to decreased oxygen levels GO:0036293 237 0.019
regulation of membrane potential GO:0042391 110 0.019
female pregnancy GO:0007565 122 0.019
immune system process GO:0002376 204 0.019
Human
cellular response to organic cyclic compound GO:0071407 202 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
single organism catabolic process GO:0044712 283 0.018
protein targeting GO:0006605 61 0.018
positive regulation of kinase activity GO:0033674 77 0.018
response to hexose GO:0009746 144 0.018
response to carbohydrate GO:0009743 183 0.018
neuron apoptotic process GO:0051402 88 0.018
tube development GO:0035295 89 0.018
Mouse
cellular ion homeostasis GO:0006873 184 0.018
action potential GO:0001508 54 0.018
protein autophosphorylation GO:0046777 66 0.018
regulation of cellular response to stress GO:0080135 49 0.018
dendrite development GO:0016358 72 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
blood circulation GO:0008015 183 0.017
regulation of lipid metabolic process GO:0019216 68 0.017
epithelium development GO:0060429 96 0.017
heterocycle catabolic process GO:0046700 167 0.017
establishment of protein localization to organelle GO:0072594 44 0.017
reproductive system development GO:0061458 128 0.017
Mouse
heart development GO:0007507 72 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
formation of primary germ layer GO:0001704 1 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
cell part morphogenesis GO:0032990 123 0.017
response to biotic stimulus GO:0009607 226 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
vasculature development GO:0001944 70 0.017
regulation of ion transport GO:0043269 245 0.017
cytoplasmic transport GO:0016482 115 0.017
regeneration GO:0031099 163 0.017
calcium ion homeostasis GO:0055074 162 0.017
regulation of neuron death GO:1901214 115 0.016
response to temperature stimulus GO:0009266 94 0.016
response to ketone GO:1901654 182 0.016
single organism cellular localization GO:1902580 102 0.016
regulation of synaptic transmission GO:0050804 141 0.016
neuron death GO:0070997 127 0.016
non canonical wnt signaling pathway GO:0035567 3 0.016
bmp signaling pathway GO:0030509 4 0.016
Human Mouse
protein homooligomerization GO:0051260 91 0.016
reproductive structure development GO:0048608 128 0.016
Mouse
negative regulation of cell cycle phase transition GO:1901988 4 0.016
single organism biosynthetic process GO:0044711 342 0.016
anion transport GO:0006820 178 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
blood vessel morphogenesis GO:0048514 58 0.016
neuronal action potential GO:0019228 35 0.016
response to heat GO:0009408 60 0.016
cell cycle process GO:0022402 57 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
mapk cascade GO:0000165 140 0.016
axon development GO:0061564 96 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
cation homeostasis GO:0055080 195 0.016
cytokine production GO:0001816 61 0.016
regulation of cellular component biogenesis GO:0044087 86 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
vesicle mediated transport GO:0016192 181 0.016
multi multicellular organism process GO:0044706 138 0.015
Mouse
multicellular organismal signaling GO:0035637 44 0.015
posttranscriptional regulation of gene expression GO:0010608 37 0.015
response to vitamin GO:0033273 131 0.015
actin cytoskeleton organization GO:0030036 73 0.015
regulation of mapk cascade GO:0043408 116 0.015
response to toxic substance GO:0009636 133 0.015
gamete generation GO:0007276 124 0.015
Mouse
negative regulation of developmental process GO:0051093 125 0.015
regulation of cell projection organization GO:0031344 175 0.015
response to purine containing compound GO:0014074 126 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
response to cytokine GO:0034097 215 0.015
response to alkaloid GO:0043279 132 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
respiratory system development GO:0060541 45 0.015
regulation of protein kinase activity GO:0045859 105 0.015
regulation of cell adhesion GO:0030155 52 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
regulation of kinase activity GO:0043549 117 0.015
sex differentiation GO:0007548 113 0.015
Mouse
cation transmembrane transport GO:0098655 263 0.015
regulation of cell migration GO:0030334 128 0.015
cellular cation homeostasis GO:0030003 180 0.015
alternative mrna splicing via spliceosome GO:0000380 4 0.015
positive regulation of transferase activity GO:0051347 81 0.015
alpha amino acid metabolic process GO:1901605 71 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
negative regulation of cell proliferation GO:0008285 119 0.014
regulation of wound healing GO:0061041 14 0.014
ion transmembrane transport GO:0034220 365 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
epithelial cell proliferation GO:0050673 54 0.014
Mouse
single organism behavior GO:0044708 130 0.014
neural crest cell differentiation GO:0014033 2 0.014
Zebrafish
development of primary sexual characteristics GO:0045137 107 0.014
Mouse
organ regeneration GO:0031100 101 0.014
digestive system development GO:0055123 41 0.014
Mouse
transmission of nerve impulse GO:0019226 42 0.014
organic anion transport GO:0015711 132 0.014
mesoderm morphogenesis GO:0048332 1 0.014
sensory organ development GO:0007423 74 0.014
regulation of developmental growth GO:0048638 45 0.014
regulation of response to wounding GO:1903034 69 0.014
regulation of hydrolase activity GO:0051336 143 0.014
regulation of hormone secretion GO:0046883 106 0.014
lung development GO:0030324 43 0.014
positive regulation of protein modification process GO:0031401 142 0.014
Human
regulation of cell growth GO:0001558 85 0.014
negative regulation of signal transduction GO:0009968 83 0.014
protein import GO:0017038 37 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
cell cycle checkpoint GO:0000075 2 0.014
mitotic cell cycle GO:0000278 49 0.013
embryonic pattern specification GO:0009880 1 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
salivary gland development GO:0007431 3 0.013
maintenance of location GO:0051235 17 0.013
muscle system process GO:0003012 115 0.013
tissue morphogenesis GO:0048729 22 0.013
protein localization to organelle GO:0033365 57 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
multicellular organism growth GO:0035264 1 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
positive regulation of bone mineralization GO:0030501 4 0.013
Human
inorganic cation transmembrane transport GO:0098662 202 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
metal ion transport GO:0030001 289 0.013
vasculogenesis GO:0001570 3 0.013
anterior posterior pattern specification GO:0009952 1 0.013
Mouse
embryonic skeletal system development GO:0048706 3 0.013
Mouse
positive regulation of cell projection organization GO:0031346 111 0.013
spermatogenesis GO:0007283 99 0.013
Mouse
dephosphorylation GO:0016311 98 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
cell projection morphogenesis GO:0048858 123 0.013
regulation of amine transport GO:0051952 54 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
negative regulation of molecular function GO:0044092 133 0.013
lipid biosynthetic process GO:0008610 128 0.013
response to insulin GO:0032868 133 0.013
circadian rhythm GO:0007623 88 0.013
nucleoside metabolic process GO:0009116 179 0.013
aromatic compound catabolic process GO:0019439 168 0.013
establishment of tissue polarity GO:0007164 2 0.013
learning or memory GO:0007611 90 0.012
embryo development GO:0009790 49 0.012
Mouse
dna metabolic process GO:0006259 96 0.012
response to reactive oxygen species GO:0000302 120 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
regulation of organelle organization GO:0033043 80 0.012
regulation of peptide transport GO:0090087 87 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
establishment of planar polarity GO:0001736 1 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
proteolysis GO:0006508 175 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
chemotaxis GO:0006935 66 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
cellular response to lipid GO:0071396 201 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
ovulation cycle GO:0042698 67 0.012
mesoderm formation GO:0001707 1 0.012
response to lipopolysaccharide GO:0032496 191 0.012
digestive tract development GO:0048565 39 0.012
Mouse
nucleoside phosphate metabolic process GO:0006753 283 0.012
regulation of ossification GO:0030278 32 0.012
Human
response to metal ion GO:0010038 253 0.012
regulation of dna metabolic process GO:0051052 60 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
positive regulation of protein transport GO:0051222 41 0.012
muscle contraction GO:0006936 88 0.012
response to mechanical stimulus GO:0009612 134 0.011
b cell differentiation GO:0030183 2 0.011
positive regulation of ion transport GO:0043270 94 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
morphogenesis of an epithelium GO:0002009 20 0.011
metal ion homeostasis GO:0055065 186 0.011
protein modification by small protein conjugation or removal GO:0070647 35 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
purine containing compound catabolic process GO:0072523 138 0.011
hormone transport GO:0009914 121 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
cell type specific apoptotic process GO:0097285 134 0.011
regulation of establishment of planar polarity GO:0090175 2 0.011
regulation of actin filament based process GO:0032970 42 0.011
chromosome segregation GO:0007059 2 0.011
cellular response to external stimulus GO:0071496 118 0.011
rho protein signal transduction GO:0007266 11 0.011
chromosome organization GO:0051276 36 0.011
response to bacterium GO:0009617 200 0.011
organic acid transport GO:0015849 116 0.011
carbohydrate metabolic process GO:0005975 130 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
muscle cell proliferation GO:0033002 84 0.011
circulatory system process GO:0003013 183 0.011
regulation of homeostatic process GO:0032844 101 0.011
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.011
protein import into nucleus GO:0006606 35 0.011
protein deubiquitination GO:0016579 4 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
urogenital system development GO:0001655 78 0.011
cellular response to glucocorticoid stimulus GO:0071385 68 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
male gamete generation GO:0048232 99 0.011
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.011
adult locomotory behavior GO:0008344 4 0.011
positive regulation of growth GO:0045927 55 0.011
muscle organ development GO:0007517 50 0.011
muscle cell differentiation GO:0042692 52 0.011
peptide transport GO:0015833 97 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
steroid metabolic process GO:0008202 73 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
regulation of protein import into nucleus GO:0042306 24 0.011
hormone metabolic process GO:0042445 69 0.010
single organism nuclear import GO:1902593 35 0.010

Acvr2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
cardiovascular system disease DOID:1287 0 0.014