Rattus norvegicus

0 known processes

Dok1

docking protein 1

(Aliases: Dok-1)

Dok1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
purine nucleoside triphosphate catabolic process GO:0009146 122 0.138
immune system process GO:0002376 204 0.087
programmed cell death GO:0012501 392 0.084
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.081
carbohydrate derivative metabolic process GO:1901135 346 0.079
intracellular signal transduction GO:0035556 314 0.077
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.073
apoptotic process GO:0006915 381 0.071
nucleoside catabolic process GO:0009164 126 0.070
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.067
transcription from rna polymerase ii promoter GO:0006366 252 0.066
anatomical structure morphogenesis GO:0009653 298 0.066
organophosphate catabolic process GO:0046434 148 0.064
brain development GO:0007420 247 0.063
protein complex subunit organization GO:0071822 302 0.063
negative regulation of neurogenesis GO:0050768 78 0.062
regulation of cellular component organization GO:0051128 368 0.062
head development GO:0060322 247 0.060
ras protein signal transduction GO:0007265 29 0.060
Mouse
regulation of apoptotic process GO:0042981 335 0.060
nucleotide catabolic process GO:0009166 139 0.058
nucleotide metabolic process GO:0009117 279 0.057
positive regulation of response to stimulus GO:0048584 285 0.056
regulation of neuron apoptotic process GO:0043523 83 0.054
regulation of transcription dna templated GO:0006355 374 0.054
regulation of rna biosynthetic process GO:2001141 381 0.052
nucleobase containing small molecule metabolic process GO:0055086 316 0.052
positive regulation of programmed cell death GO:0043068 157 0.052
regulation of cellular protein metabolic process GO:0032268 267 0.051
rna metabolic process GO:0016070 406 0.051
cellular component biogenesis GO:0044085 368 0.047
ribonucleotide metabolic process GO:0009259 231 0.046
negative regulation of neuron differentiation GO:0045665 62 0.045
central nervous system development GO:0007417 311 0.045
protein complex biogenesis GO:0070271 263 0.045
erythrocyte differentiation GO:0030218 1 0.044
regulation of signal transduction GO:0009966 318 0.043
cellular catabolic process GO:0044248 295 0.042
purine nucleotide metabolic process GO:0006163 229 0.042
positive regulation of gene expression GO:0010628 244 0.041
organophosphate metabolic process GO:0019637 370 0.039
carbohydrate derivative catabolic process GO:1901136 147 0.039
negative regulation of programmed cell death GO:0043069 183 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
regulation of cell proliferation GO:0042127 359 0.039
regulation of catalytic activity GO:0050790 304 0.038
nucleoside phosphate metabolic process GO:0006753 283 0.038
negative regulation of immune system process GO:0002683 39 0.038
nucleoside phosphate catabolic process GO:1901292 140 0.038
ribonucleoside triphosphate metabolic process GO:0009199 141 0.038
nucleoside metabolic process GO:0009116 179 0.038
cellular nitrogen compound catabolic process GO:0044270 163 0.038
signal transduction by phosphorylation GO:0023014 144 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
nucleic acid templated transcription GO:0097659 379 0.037
aromatic compound catabolic process GO:0019439 168 0.037
regulation of protein metabolic process GO:0051246 289 0.037
small gtpase mediated signal transduction GO:0007264 36 0.037
Mouse
neuron differentiation GO:0030182 368 0.037
regulation of small gtpase mediated signal transduction GO:0051056 48 0.036
protein complex assembly GO:0006461 263 0.036
negative regulation of metabolic process GO:0009892 331 0.036
macromolecular complex assembly GO:0065003 273 0.036
heterocycle catabolic process GO:0046700 167 0.036
guanosine containing compound metabolic process GO:1901068 74 0.036
purine ribonucleotide catabolic process GO:0009154 136 0.036
negative regulation of nervous system development GO:0051961 79 0.036
purine nucleoside metabolic process GO:0042278 169 0.035
regulation of rna metabolic process GO:0051252 391 0.035
regulation of multicellular organismal development GO:2000026 376 0.035
regulation of molecular function GO:0065009 398 0.035
organic cyclic compound catabolic process GO:1901361 175 0.034
immune response GO:0006955 104 0.034
negative regulation of cell development GO:0010721 82 0.034
regulation of neuron death GO:1901214 115 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.033
organic substance catabolic process GO:1901575 316 0.033
regulation of immune system process GO:0002682 123 0.033
regulation of nervous system development GO:0051960 264 0.033
cellular response to hormone stimulus GO:0032870 247 0.033
cytoskeleton organization GO:0007010 111 0.032
b cell differentiation GO:0030183 2 0.032
ribonucleoside triphosphate catabolic process GO:0009203 122 0.031
regulation of neuron differentiation GO:0045664 208 0.031
purine nucleotide catabolic process GO:0006195 136 0.031
negative regulation of molecular function GO:0044092 133 0.031
cellular response to peptide GO:1901653 133 0.031
response to peptide hormone GO:0043434 278 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.031
gtp catabolic process GO:0006184 71 0.030
response to peptide GO:1901652 292 0.030
single organism organelle organization GO:1902589 180 0.030
glycosyl compound metabolic process GO:1901657 182 0.030
homeostatic process GO:0042592 331 0.030
purine nucleoside triphosphate metabolic process GO:0009144 141 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
transcription dna templated GO:0006351 377 0.029
positive regulation of apoptotic process GO:0043065 154 0.029
catabolic process GO:0009056 351 0.029
negative regulation of neuron apoptotic process GO:0043524 45 0.029
negative regulation of cell communication GO:0010648 158 0.029
ribonucleotide catabolic process GO:0009261 136 0.028
rna biosynthetic process GO:0032774 380 0.028
regulation of neurogenesis GO:0050767 247 0.027
defense response GO:0006952 194 0.027
regulation of cell development GO:0060284 263 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
purine containing compound catabolic process GO:0072523 138 0.027
negative regulation of catalytic activity GO:0043086 103 0.027
nucleobase containing compound catabolic process GO:0034655 152 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
negative regulation of protein metabolic process GO:0051248 114 0.026
regulation of nucleotide catabolic process GO:0030811 65 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
carboxylic acid metabolic process GO:0019752 289 0.026
regulation of programmed cell death GO:0043067 341 0.026
neuron projection development GO:0031175 273 0.026
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.025
regulation of cell differentiation GO:0045595 320 0.025
response to hypoxia GO:0001666 231 0.025
cellular component assembly GO:0022607 360 0.025
purine nucleoside catabolic process GO:0006152 124 0.025
multicellular organism reproduction GO:0032504 233 0.024
alcohol metabolic process GO:0006066 77 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
gtp metabolic process GO:0046039 72 0.024
protein phosphorylation GO:0006468 345 0.024
response to ethanol GO:0045471 162 0.024
response to inorganic substance GO:0010035 377 0.024
response to insulin GO:0032868 133 0.024
organic acid metabolic process GO:0006082 292 0.023
protein oligomerization GO:0051259 191 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
regulation of nucleic acid templated transcription GO:1903506 380 0.023
negative regulation of cell death GO:0060548 229 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
positive regulation of intracellular signal transduction GO:1902533 138 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
single organism catabolic process GO:0044712 283 0.023
regulation of ras gtpase activity GO:0032318 32 0.023
nitrogen compound transport GO:0071705 229 0.023
dna metabolic process GO:0006259 96 0.023
immunoglobulin mediated immune response GO:0016064 4 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
regulation of gtpase activity GO:0043087 57 0.022
regulation of cytokine production GO:0001817 56 0.022
cytokine biosynthetic process GO:0042089 3 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
positive regulation of developmental process GO:0051094 283 0.022
regulation of phosphorylation GO:0042325 248 0.022
regulation of protein complex assembly GO:0043254 33 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
erythrocyte homeostasis GO:0034101 2 0.021
positive regulation of signal transduction GO:0009967 175 0.021
neuron death GO:0070997 127 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
regulation of map kinase activity GO:0043405 53 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.021
positive regulation of cell communication GO:0010647 271 0.021
positive regulation of ras gtpase activity GO:0032320 28 0.020
regeneration GO:0031099 163 0.020
glycosyl compound catabolic process GO:1901658 126 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
positive regulation of neuron projection development GO:0010976 99 0.020
aging GO:0007568 241 0.020
regulation of neuron projection development GO:0010975 161 0.020
response to toxic substance GO:0009636 133 0.020
cytokine production GO:0001816 61 0.019
single organism reproductive process GO:0044702 297 0.019
regulation of hydrolase activity GO:0051336 143 0.019
rhythmic process GO:0048511 156 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
Mouse
positive regulation of cell development GO:0010720 176 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
guanosine containing compound catabolic process GO:1901069 71 0.019
multi organism reproductive process GO:0044703 262 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.018
cell projection organization GO:0030030 302 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
positive regulation of nervous system development GO:0051962 178 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
regulation of transferase activity GO:0051338 123 0.018
positive regulation of gtpase activity GO:0043547 47 0.018
regulation of cell projection organization GO:0031344 175 0.018
regulation of ras protein signal transduction GO:0046578 45 0.018
insulin like growth factor receptor signaling pathway GO:0048009 3 0.018
negative regulation of neuron death GO:1901215 69 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
negative regulation of cytokine production GO:0001818 16 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
chemical homeostasis GO:0048878 292 0.018
regulation of cellular catabolic process GO:0031329 101 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
positive regulation of leukocyte activation GO:0002696 30 0.017
regulation of nucleoside metabolic process GO:0009118 66 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
regulation of protein kinase activity GO:0045859 105 0.017
b cell mediated immunity GO:0019724 4 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
secretion GO:0046903 307 0.017
positive regulation of molecular function GO:0044093 230 0.017
regulation of protein serine threonine kinase activity GO:0071900 64 0.017
cellular ketone metabolic process GO:0042180 51 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
regulation of hormone levels GO:0010817 187 0.016
reproductive process GO:0022414 372 0.016
regulation of cellular localization GO:0060341 263 0.016
negative regulation of cell differentiation GO:0045596 99 0.016
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
positive regulation of catabolic process GO:0009896 78 0.016
positive regulation of map kinase activity GO:0043406 46 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
cellular response to insulin stimulus GO:0032869 81 0.016
purine containing compound metabolic process GO:0072521 253 0.016
negative regulation of neuron projection development GO:0010977 46 0.016
calcium ion homeostasis GO:0055074 162 0.016
regulation of leukocyte activation GO:0002694 45 0.016
cell type specific apoptotic process GO:0097285 134 0.015
hematopoietic or lymphoid organ development GO:0048534 36 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
regulation of cytokine biosynthetic process GO:0042035 3 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
Mouse
purine ribonucleoside metabolic process GO:0046128 168 0.015
regulation of immune response GO:0050776 55 0.015
lymphocyte activation GO:0046649 43 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
interleukin 6 production GO:0032635 12 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
cardiovascular system development GO:0072358 134 0.015
oxoacid metabolic process GO:0043436 290 0.015
organelle organization GO:0006996 266 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
neuron development GO:0048666 286 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
response to corticosteroid GO:0031960 235 0.015
sex differentiation GO:0007548 113 0.015
single organism biosynthetic process GO:0044711 342 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
amine metabolic process GO:0009308 38 0.014
regulation of response to stress GO:0080134 126 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
transmembrane transport GO:0055085 412 0.014
positive regulation of signaling GO:0023056 270 0.014
amide transport GO:0042886 105 0.014
positive regulation of immune system process GO:0002684 90 0.014
circulatory system process GO:0003013 183 0.014
positive regulation of homeostatic process GO:0032846 49 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
cellular response to stress GO:0033554 269 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
response to reactive oxygen species GO:0000302 120 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of protein modification process GO:0031399 194 0.013
dna replication GO:0006260 37 0.013
cellular amine metabolic process GO:0044106 38 0.013
insulin receptor signaling pathway GO:0008286 24 0.013
metal ion homeostasis GO:0055065 186 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
anion transport GO:0006820 178 0.013
biological adhesion GO:0022610 110 0.013
protein heterooligomerization GO:0051291 89 0.013
developmental process involved in reproduction GO:0003006 159 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
ion transmembrane transport GO:0034220 365 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
response to oxygen levels GO:0070482 265 0.013
development of primary sexual characteristics GO:0045137 107 0.013
small molecule biosynthetic process GO:0044283 124 0.013
neuron apoptotic process GO:0051402 88 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
positive regulation of cell death GO:0010942 184 0.012
organ regeneration GO:0031100 101 0.012
multicellular organismal homeostasis GO:0048871 49 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
regulation of homeostatic process GO:0032844 101 0.012
response to glucocorticoid GO:0051384 223 0.012
reproductive structure development GO:0048608 128 0.012
gonad development GO:0008406 104 0.012
negative regulation of osteoclast differentiation GO:0045671 1 0.012
hormone secretion GO:0046879 115 0.012
immune effector process GO:0002252 53 0.012
female sex differentiation GO:0046660 59 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
reproduction GO:0000003 245 0.012
response to cytokine GO:0034097 215 0.012
response to extracellular stimulus GO:0009991 380 0.012
anterior posterior pattern specification GO:0009952 1 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
myeloid leukocyte differentiation GO:0002573 20 0.012
response to hexose GO:0009746 144 0.012
cognition GO:0050890 92 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
leukocyte activation GO:0045321 76 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
multi multicellular organism process GO:0044706 138 0.011
negative regulation of interleukin 6 production GO:0032715 4 0.011
cation homeostasis GO:0055080 195 0.011
response to ketone GO:1901654 182 0.011
circadian rhythm GO:0007623 88 0.011
sexual reproduction GO:0019953 148 0.011
single organism behavior GO:0044708 130 0.011
response to decreased oxygen levels GO:0036293 237 0.011
rho protein signal transduction GO:0007266 11 0.011
female pregnancy GO:0007565 122 0.011
hormone transport GO:0009914 121 0.011
response to estrogen GO:0043627 232 0.011
negative regulation of transport GO:0051051 136 0.011
lipid metabolic process GO:0006629 283 0.011
mapk cascade GO:0000165 140 0.011
gastrulation GO:0007369 2 0.011
eye morphogenesis GO:0048592 4 0.010
negative regulation of innate immune response GO:0045824 4 0.010
axis specification GO:0009798 4 0.010
response to metal ion GO:0010038 253 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
negative regulation of signaling GO:0023057 157 0.010
microtubule organizing center organization GO:0031023 1 0.010
behavior GO:0007610 205 0.010
actin cytoskeleton organization GO:0030036 73 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
negative regulation of phosphorylation GO:0042326 57 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
blood vessel morphogenesis GO:0048514 58 0.010

Dok1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.010