Rattus norvegicus

79 known processes

Phlpp1

PH domain and leucine rich repeat protein phosphatase 1

(Aliases: Phlpp,Scop,Plekhe1)

Phlpp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.150
protein phosphorylation GO:0006468 345 0.138
positive regulation of phosphate metabolic process GO:0045937 262 0.128
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.125
positive regulation of catalytic activity GO:0043085 184 0.122
cellular ketone metabolic process GO:0042180 51 0.116
regulation of molecular function GO:0065009 398 0.113
regulation of cellular protein metabolic process GO:0032268 267 0.095
regulation of phosphorus metabolic process GO:0051174 349 0.094
regulation of cellular component organization GO:0051128 368 0.092
positive regulation of cell communication GO:0010647 271 0.091
regulation of rna biosynthetic process GO:2001141 381 0.088
regulation of phosphate metabolic process GO:0019220 349 0.084
regulation of intracellular signal transduction GO:1902531 218 0.082
positive regulation of multicellular organismal process GO:0051240 387 0.082
regulation of multicellular organismal development GO:2000026 376 0.081
regulation of cellular ketone metabolic process GO:0010565 27 0.081
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.079
positive regulation of signal transduction GO:0009967 175 0.078
regulation of rna metabolic process GO:0051252 391 0.076
transcription dna templated GO:0006351 377 0.075
rna biosynthetic process GO:0032774 380 0.075
amine metabolic process GO:0009308 38 0.075
regulation of neuron differentiation GO:0045664 208 0.074
neuron differentiation GO:0030182 368 0.074
regulation of cell development GO:0060284 263 0.072
cellular amine metabolic process GO:0044106 38 0.071
regulation of signal transduction GO:0009966 318 0.071
regulation of phosphorylation GO:0042325 248 0.070
positive regulation of response to stimulus GO:0048584 285 0.068
oxoacid metabolic process GO:0043436 290 0.067
cellular response to endogenous stimulus GO:0071495 377 0.066
regulation of protein phosphorylation GO:0001932 183 0.066
cellular amino acid metabolic process GO:0006520 107 0.066
programmed cell death GO:0012501 392 0.064
Fly
rna metabolic process GO:0016070 406 0.064
negative regulation of metabolic process GO:0009892 331 0.063
regulation of hydrolase activity GO:0051336 143 0.063
carboxylic acid metabolic process GO:0019752 289 0.063
regulation of neurogenesis GO:0050767 247 0.062
aromatic compound catabolic process GO:0019439 168 0.062
regulation of kinase activity GO:0043549 117 0.061
catabolic process GO:0009056 351 0.060
positive regulation of signaling GO:0023056 270 0.059
regulation of catalytic activity GO:0050790 304 0.059
regulation of nucleic acid templated transcription GO:1903506 380 0.058
single organism catabolic process GO:0044712 283 0.057
positive regulation of molecular function GO:0044093 230 0.057
positive regulation of cellular protein metabolic process GO:0032270 167 0.056
positive regulation of phosphorus metabolic process GO:0010562 262 0.055
organic acid metabolic process GO:0006082 292 0.055
positive regulation of rna metabolic process GO:0051254 203 0.054
neuron projection development GO:0031175 273 0.054
regulation of cellular amine metabolic process GO:0033238 8 0.054
apoptotic process GO:0006915 381 0.053
Fly
regulation of programmed cell death GO:0043067 341 0.052
Fly
regulation of apoptotic process GO:0042981 335 0.052
Fly
regulation of cellular amino acid metabolic process GO:0006521 2 0.052
regulation of nervous system development GO:0051960 264 0.052
regulation of neuron projection development GO:0010975 161 0.052
cellular component assembly GO:0022607 360 0.051
cellular nitrogen compound catabolic process GO:0044270 163 0.051
response to growth factor GO:0070848 189 0.051
regulation of cell differentiation GO:0045595 320 0.050
positive regulation of gene expression GO:0010628 244 0.050
cell projection organization GO:0030030 302 0.050
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.049
regulation of catabolic process GO:0009894 113 0.048
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.048
regulation of transferase activity GO:0051338 123 0.048
regulation of transcription dna templated GO:0006355 374 0.048
regulation of cellular catabolic process GO:0031329 101 0.048
response to extracellular stimulus GO:0009991 380 0.047
response to peptide hormone GO:0043434 278 0.047
enzyme linked receptor protein signaling pathway GO:0007167 116 0.047
negative regulation of signaling GO:0023057 157 0.046
positive regulation of protein metabolic process GO:0051247 178 0.046
small gtpase mediated signal transduction GO:0007264 36 0.046
organic cyclic compound catabolic process GO:1901361 175 0.046
positive regulation of phosphorylation GO:0042327 177 0.046
nucleic acid templated transcription GO:0097659 379 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.045
central nervous system development GO:0007417 311 0.045
regulation of protein modification process GO:0031399 194 0.044
positive regulation of cellular component organization GO:0051130 200 0.044
negative regulation of cellular metabolic process GO:0031324 281 0.043
organic substance catabolic process GO:1901575 316 0.043
positive regulation of cellular amine metabolic process GO:0033240 3 0.042
cellular response to oxygen containing compound GO:1901701 386 0.041
response to peptide GO:1901652 292 0.041
transcription from rna polymerase ii promoter GO:0006366 252 0.041
negative regulation of macromolecule metabolic process GO:0010605 260 0.041
transmission of nerve impulse GO:0019226 42 0.040
positive regulation of neurogenesis GO:0050769 165 0.040
positive regulation of mapk cascade GO:0043410 92 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.040
nucleobase containing compound catabolic process GO:0034655 152 0.039
regulation of proteasomal protein catabolic process GO:0061136 4 0.039
heterocycle catabolic process GO:0046700 167 0.039
neuron development GO:0048666 286 0.039
macromolecule localization GO:0033036 252 0.038
purine ribonucleoside catabolic process GO:0046130 124 0.038
response to nutrient levels GO:0031667 370 0.038
negative regulation of developmental process GO:0051093 125 0.038
cellular response to hormone stimulus GO:0032870 247 0.037
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.037
ribonucleotide metabolic process GO:0009259 231 0.036
ribonucleoside triphosphate metabolic process GO:0009199 141 0.035
positive regulation of intracellular signal transduction GO:1902533 138 0.035
positive regulation of programmed cell death GO:0043068 157 0.035
myelination GO:0042552 39 0.035
guanosine containing compound metabolic process GO:1901068 74 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.035
protein complex assembly GO:0006461 263 0.035
regulation of protein kinase activity GO:0045859 105 0.034
positive regulation of rna biosynthetic process GO:1902680 197 0.034
anatomical structure morphogenesis GO:0009653 298 0.034
ras protein signal transduction GO:0007265 29 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
organelle organization GO:0006996 266 0.034
glycosyl compound catabolic process GO:1901658 126 0.034
positive regulation of developmental process GO:0051094 283 0.034
response to estradiol GO:0032355 164 0.033
negative regulation of cell death GO:0060548 229 0.033
purine ribonucleotide catabolic process GO:0009154 136 0.033
positive regulation of cell development GO:0010720 176 0.033
cellular response to stress GO:0033554 269 0.033
positive regulation of biosynthetic process GO:0009891 319 0.033
multicellular organismal signaling GO:0035637 44 0.033
action potential GO:0001508 54 0.033
negative regulation of apoptotic process GO:0043066 181 0.032
response to estrogen GO:0043627 232 0.032
vesicle mediated transport GO:0016192 181 0.032
regulation of protein metabolic process GO:0051246 289 0.032
positive regulation of protein phosphorylation GO:0001934 135 0.032
nucleoside catabolic process GO:0009164 126 0.032
negative regulation of programmed cell death GO:0043069 183 0.032
regulation of mapk cascade GO:0043408 116 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.031
cell part morphogenesis GO:0032990 123 0.031
regulation of membrane potential GO:0042391 110 0.031
positive regulation of cell projection organization GO:0031346 111 0.031
regulation of anatomical structure morphogenesis GO:0022603 141 0.031
single organism reproductive process GO:0044702 297 0.031
gtp catabolic process GO:0006184 71 0.031
positive regulation of nucleoside metabolic process GO:0045979 55 0.031
regulation of dendrite development GO:0050773 59 0.031
purine ribonucleotide metabolic process GO:0009150 227 0.030
positive regulation of hydrolase activity GO:0051345 86 0.030
regulation of small gtpase mediated signal transduction GO:0051056 48 0.030
cellular response to growth factor stimulus GO:0071363 162 0.030
organonitrogen compound catabolic process GO:1901565 179 0.030
cell motility GO:0048870 202 0.030
nucleoside triphosphate catabolic process GO:0009143 123 0.030
cellular response to cytokine stimulus GO:0071345 127 0.030
positive regulation of cell differentiation GO:0045597 217 0.029
purine containing compound metabolic process GO:0072521 253 0.029
regulation of cell projection organization GO:0031344 175 0.029
ribonucleoside triphosphate catabolic process GO:0009203 122 0.029
regulation of purine nucleotide catabolic process GO:0033121 65 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
positive regulation of apoptotic process GO:0043065 154 0.029
negative regulation of cellular biosynthetic process GO:0031327 161 0.029
carbohydrate derivative catabolic process GO:1901136 147 0.028
neuronal action potential GO:0019228 35 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.028
cation transport GO:0006812 382 0.028
regulation of cellular localization GO:0060341 263 0.028
positive regulation of cellular catabolic process GO:0031331 71 0.028
cell type specific apoptotic process GO:0097285 134 0.028
mapk cascade GO:0000165 140 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
purine nucleoside metabolic process GO:0042278 169 0.027
regulation of gtpase activity GO:0043087 57 0.027
response to nutrient GO:0007584 248 0.027
ion transmembrane transport GO:0034220 365 0.027
cellular component movement GO:0006928 248 0.027
nitrogen compound transport GO:0071705 229 0.027
establishment of protein localization GO:0045184 141 0.027
nucleoside metabolic process GO:0009116 179 0.027
glycosyl compound metabolic process GO:1901657 182 0.026
purine nucleotide metabolic process GO:0006163 229 0.026
nucleotide catabolic process GO:0009166 139 0.026
ribonucleoside metabolic process GO:0009119 174 0.026
protein complex biogenesis GO:0070271 263 0.026
positive regulation of kinase activity GO:0033674 77 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
ribonucleoside catabolic process GO:0042454 126 0.026
cellular catabolic process GO:0044248 295 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
regulation of secretion GO:0051046 224 0.026
cellular response to external stimulus GO:0071496 118 0.026
purine containing compound catabolic process GO:0072523 138 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.026
cellular lipid metabolic process GO:0044255 208 0.026
negative regulation of biosynthetic process GO:0009890 168 0.025
nucleotide metabolic process GO:0009117 279 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.025
response to oxygen levels GO:0070482 265 0.025
cell migration GO:0016477 197 0.025
organophosphate catabolic process GO:0046434 148 0.025
organophosphate metabolic process GO:0019637 370 0.025
regulation of erk1 and erk2 cascade GO:0070372 41 0.025
macromolecular complex assembly GO:0065003 273 0.025
single organism intracellular transport GO:1902582 166 0.025
neurological system process GO:0050877 219 0.025
positive regulation of transferase activity GO:0051347 81 0.025
cell projection morphogenesis GO:0048858 123 0.025
regulation of purine nucleotide metabolic process GO:1900542 115 0.025
protein complex subunit organization GO:0071822 302 0.025
positive regulation of protein modification process GO:0031401 142 0.025
protein oligomerization GO:0051259 191 0.024
negative regulation of gene expression GO:0010629 199 0.024
transmembrane transport GO:0055085 412 0.024
positive regulation of neuron differentiation GO:0045666 126 0.024
single organism organelle organization GO:1902589 180 0.024
erk1 and erk2 cascade GO:0070371 48 0.024
positive regulation of neuron projection development GO:0010976 99 0.024
regulation of cell proliferation GO:0042127 359 0.024
cardiovascular system development GO:0072358 134 0.023
purine nucleoside triphosphate metabolic process GO:0009144 141 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
nucleoside triphosphate metabolic process GO:0009141 144 0.023
chemical homeostasis GO:0048878 292 0.023
nucleoside phosphate catabolic process GO:1901292 140 0.023
growth GO:0040007 165 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
regulation of gtp catabolic process GO:0033124 58 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
cell morphogenesis GO:0000902 142 0.023
cellular component biogenesis GO:0044085 368 0.023
secretion GO:0046903 307 0.022
negative regulation of nervous system development GO:0051961 79 0.022
positive regulation of protein kinase activity GO:0045860 73 0.022
purine nucleotide catabolic process GO:0006195 136 0.022
synaptic growth at neuromuscular junction GO:0051124 1 0.022
negative regulation of transport GO:0051051 136 0.022
positive regulation of catabolic process GO:0009896 78 0.022
peptidyl amino acid modification GO:0018193 126 0.022
response to hexose GO:0009746 144 0.022
multi organism reproductive process GO:0044703 262 0.022
regulation of cellular component movement GO:0051270 150 0.022
purine ribonucleoside metabolic process GO:0046128 168 0.022
head development GO:0060322 247 0.022
metal ion transport GO:0030001 289 0.022
homeostatic process GO:0042592 331 0.022
purine nucleoside triphosphate catabolic process GO:0009146 122 0.022
regulation of nucleoside metabolic process GO:0009118 66 0.022
proteolysis GO:0006508 175 0.021
regulation of nucleotide catabolic process GO:0030811 65 0.021
response to monosaccharide GO:0034284 159 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
circulatory system development GO:0072359 134 0.021
response to glucose GO:0009749 136 0.021
regulation of cell migration GO:0030334 128 0.021
negative regulation of signal transduction GO:0009968 83 0.021
response to ketone GO:1901654 182 0.021
response to carbohydrate GO:0009743 183 0.021
regulation of transmembrane transport GO:0034762 122 0.021
neuron projection morphogenesis GO:0048812 122 0.020
regulation of cell growth GO:0001558 85 0.020
oxidation reduction process GO:0055114 304 0.020
negative regulation of rna metabolic process GO:0051253 123 0.020
protein transport GO:0015031 132 0.020
localization of cell GO:0051674 202 0.020
cell growth GO:0016049 104 0.020
axon ensheathment GO:0008366 40 0.020
carboxylic acid transport GO:0046942 115 0.020
positive regulation of nucleotide metabolic process GO:0045981 91 0.020
ion homeostasis GO:0050801 212 0.020
positive regulation of gtpase activity GO:0043547 47 0.020
cellular homeostasis GO:0019725 252 0.019
tissue development GO:0009888 252 0.019
regulation of growth GO:0040008 105 0.019
positive regulation of nucleotide catabolic process GO:0030813 53 0.019
anion transport GO:0006820 178 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
purine nucleoside catabolic process GO:0006152 124 0.019
regulation of response to stress GO:0080134 126 0.019
anterior posterior pattern specification GO:0009952 1 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
ribonucleotide catabolic process GO:0009261 136 0.019
regulation of protein localization GO:0032880 81 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
positive regulation of gtp catabolic process GO:0033126 48 0.019
negative regulation of cell development GO:0010721 82 0.019
organic anion transport GO:0015711 132 0.019
protein localization GO:0008104 191 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.018
reactive nitrogen species metabolic process GO:2001057 1 0.018
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.018
cellular chemical homeostasis GO:0055082 247 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
reproductive process GO:0022414 372 0.018
brain development GO:0007420 247 0.018
positive regulation of cell death GO:0010942 184 0.018
response to organophosphorus GO:0046683 102 0.018
synaptic transmission GO:0007268 235 0.018
gtp metabolic process GO:0046039 72 0.018
maintenance of location GO:0051235 17 0.018
amino acid transport GO:0006865 70 0.018
regulation of system process GO:0044057 208 0.018
cellular ion homeostasis GO:0006873 184 0.017
response to hypoxia GO:0001666 231 0.017
positive regulation of nervous system development GO:0051962 178 0.017
protein autophosphorylation GO:0046777 66 0.017
regulation of neuron death GO:1901214 115 0.017
neuron death GO:0070997 127 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
positive regulation of transport GO:0051050 245 0.017
response to vitamin GO:0033273 131 0.017
cytoplasmic transport GO:0016482 115 0.016
regulation of secretion by cell GO:1903530 208 0.016
locomotion GO:0040011 237 0.016
single organism biosynthetic process GO:0044711 342 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
regulation of cell motility GO:2000145 131 0.016
lipid storage GO:0019915 1 0.016
cellular component morphogenesis GO:0032989 155 0.016
cytoskeleton organization GO:0007010 111 0.016
regulation of response to external stimulus GO:0032101 106 0.016
reproduction GO:0000003 245 0.016
response to decreased oxygen levels GO:0036293 237 0.016
ensheathment of neurons GO:0007272 40 0.016
regulation of anatomical structure size GO:0090066 135 0.016
inflammatory response GO:0006954 150 0.016
response to reactive oxygen species GO:0000302 120 0.016
negative regulation of cell communication GO:0010648 158 0.016
response to inorganic substance GO:0010035 377 0.016
regulation of cellular component biogenesis GO:0044087 86 0.016
amide transport GO:0042886 105 0.016
dendrite development GO:0016358 72 0.016
regulation of ion transport GO:0043269 245 0.015
single organism membrane organization GO:0044802 74 0.015
lipid metabolic process GO:0006629 283 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
cell cell signaling GO:0007267 335 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
cellular response to abiotic stimulus GO:0071214 85 0.015
gastrulation GO:0007369 2 0.015
lipid biosynthetic process GO:0008610 128 0.015
muscle system process GO:0003012 115 0.015
cation homeostasis GO:0055080 195 0.015
response to oxidative stress GO:0006979 186 0.015
regulation of ras protein signal transduction GO:0046578 45 0.015
defense response GO:0006952 194 0.015
response to insulin GO:0032868 133 0.015
positive regulation of ion transport GO:0043270 94 0.015
membrane organization GO:0061024 94 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
response to hydrogen peroxide GO:0042542 89 0.015
regulation of ras gtpase activity GO:0032318 32 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
macromolecule catabolic process GO:0009057 58 0.014
heart development GO:0007507 72 0.014
cell cycle GO:0007049 101 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
regulation of fat cell differentiation GO:0045598 3 0.014
response to mechanical stimulus GO:0009612 134 0.014
peptide transport GO:0015833 97 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
response to acid chemical GO:0001101 222 0.014
regeneration GO:0031099 163 0.014
female pregnancy GO:0007565 122 0.014
response to wounding GO:0009611 254 0.014
intracellular transport GO:0046907 185 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
behavior GO:0007610 205 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
response to glucocorticoid GO:0051384 223 0.014
circadian rhythm GO:0007623 88 0.014
rhythmic process GO:0048511 156 0.014
cellular response to peptide GO:1901653 133 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
cellular protein localization GO:0034613 122 0.014
regulation of synaptic transmission GO:0050804 141 0.014
immune system process GO:0002376 204 0.014
biological adhesion GO:0022610 110 0.014
cellular response to lipid GO:0071396 201 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
response to cytokine GO:0034097 215 0.014
cellular macromolecule localization GO:0070727 122 0.014
muscle cell proliferation GO:0033002 84 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
secretion by cell GO:0032940 248 0.014
regulation of neuron apoptotic process GO:0043523 83 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
peptidyl serine phosphorylation GO:0018105 33 0.013
single organism cellular localization GO:1902580 102 0.013
regulation of locomotion GO:0040012 148 0.013
regulation of protein serine threonine kinase activity GO:0071900 64 0.013
regulation of protein transport GO:0051223 68 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
bmp signaling pathway GO:0030509 4 0.013
response to purine containing compound GO:0014074 126 0.013
response to temperature stimulus GO:0009266 94 0.013
cell adhesion GO:0007155 110 0.013
heart morphogenesis GO:0003007 3 0.013
regulation of peptide transport GO:0090087 87 0.013
negative regulation of molecular function GO:0044092 133 0.013
response to camp GO:0051591 91 0.013
neuron apoptotic process GO:0051402 88 0.013
cation transmembrane transport GO:0098655 263 0.013
organic acid transport GO:0015849 116 0.013
blood circulation GO:0008015 183 0.013
gland development GO:0048732 155 0.013
peptidyl serine modification GO:0018209 34 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.012
positive regulation of cell migration GO:0030335 96 0.012
spindle organization GO:0007051 2 0.012
aging GO:0007568 241 0.012
metal ion homeostasis GO:0055065 186 0.012
cellular response to oxidative stress GO:0034599 76 0.012
regulation of hormone levels GO:0010817 187 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
glucose homeostasis GO:0042593 75 0.012
multi multicellular organism process GO:0044706 138 0.012
intracellular protein transport GO:0006886 79 0.012
response to ethanol GO:0045471 162 0.012
regulation of response to wounding GO:1903034 69 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
lipid transport GO:0006869 61 0.012
response to lipopolysaccharide GO:0032496 191 0.012
mesoderm development GO:0007498 2 0.012
regulation of g0 to g1 transition GO:0070316 3 0.012
regulation of intracellular transport GO:0032386 65 0.011
positive regulation of cell motility GO:2000147 97 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
multicellular organism growth GO:0035264 1 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
rna catabolic process GO:0006401 3 0.011
response to corticosteroid GO:0031960 235 0.011
response to cgmp GO:0070305 3 0.011
multicellular organism reproduction GO:0032504 233 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
activation of protein kinase b activity GO:0032148 3 0.011
reproductive system development GO:0061458 128 0.011
positive regulation of ras gtpase activity GO:0032320 28 0.011
axis specification GO:0009798 4 0.011
response to bacterium GO:0009617 200 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
regulation of proteolysis GO:0030162 66 0.011
glycogen metabolic process GO:0005977 23 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
embryonic pattern specification GO:0009880 1 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
telencephalon development GO:0021537 62 0.011
calcium ion homeostasis GO:0055074 162 0.011
oligopeptide transport GO:0006857 4 0.011
regulation of metal ion transport GO:0010959 118 0.011
muscle structure development GO:0061061 87 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
learning or memory GO:0007611 90 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
cellular cation homeostasis GO:0030003 180 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
sexual reproduction GO:0019953 148 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
chromosome segregation GO:0007059 2 0.011
apoptotic signaling pathway GO:0097190 27 0.011
regulation of g2 m transition of mitotic cell cycle GO:0010389 4 0.011
regulation of homeostatic process GO:0032844 101 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.010
response to biotic stimulus GO:0009607 226 0.010
epithelium development GO:0060429 96 0.010
gamete generation GO:0007276 124 0.010
response to radiation GO:0009314 137 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
vascular process in circulatory system GO:0003018 96 0.010
single organism nuclear import GO:1902593 35 0.010
gliogenesis GO:0042063 93 0.010
response to metal ion GO:0010038 253 0.010

Phlpp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of metabolism DOID:0014667 0 0.015
sensory system disease DOID:0050155 0 0.014
central nervous system disease DOID:331 0 0.012