Rattus norvegicus

0 known processes

Galc

galactosylceramidase

Galc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.063
carboxylic acid metabolic process GO:0019752 289 0.056
organic acid metabolic process GO:0006082 292 0.051
response to extracellular stimulus GO:0009991 380 0.043
cellular component assembly GO:0022607 360 0.041
cellular response to endogenous stimulus GO:0071495 377 0.039
response to nutrient levels GO:0031667 370 0.039
cellular component biogenesis GO:0044085 368 0.039
reproductive process GO:0022414 372 0.036
intracellular signal transduction GO:0035556 314 0.033
neuron differentiation GO:0030182 368 0.033
cellular amino acid metabolic process GO:0006520 107 0.032
protein complex assembly GO:0006461 263 0.031
regulation of programmed cell death GO:0043067 341 0.031
transmembrane transport GO:0055085 412 0.031
single organism reproductive process GO:0044702 297 0.030
response to nutrient GO:0007584 248 0.030
single organism catabolic process GO:0044712 283 0.030
multi organism reproductive process GO:0044703 262 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
macromolecular complex assembly GO:0065003 273 0.029
response to peptide hormone GO:0043434 278 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
cation transport GO:0006812 382 0.028
organelle organization GO:0006996 266 0.028
protein phosphorylation GO:0006468 345 0.028
cellular amine metabolic process GO:0044106 38 0.027
response to peptide GO:1901652 292 0.027
nucleotide metabolic process GO:0009117 279 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
organophosphate metabolic process GO:0019637 370 0.026
amine metabolic process GO:0009308 38 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
protein complex subunit organization GO:0071822 302 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
catabolic process GO:0009056 351 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
central nervous system development GO:0007417 311 0.025
cellular ketone metabolic process GO:0042180 51 0.025
single organism biosynthetic process GO:0044711 342 0.025
response to inorganic substance GO:0010035 377 0.025
regulation of molecular function GO:0065009 398 0.025
organic anion transport GO:0015711 132 0.025
anion transport GO:0006820 178 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
multicellular organismal reproductive process GO:0048609 233 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
response to oxygen levels GO:0070482 265 0.024
lipid metabolic process GO:0006629 283 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
protein complex biogenesis GO:0070271 263 0.024
regulation of rna metabolic process GO:0051252 391 0.024
regulation of cellular component organization GO:0051128 368 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
response to hypoxia GO:0001666 231 0.024
cell projection organization GO:0030030 302 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
ion transmembrane transport GO:0034220 365 0.023
multicellular organism reproduction GO:0032504 233 0.023
reproduction GO:0000003 245 0.023
response to corticosteroid GO:0031960 235 0.023
homeostatic process GO:0042592 331 0.023
regulation of apoptotic process GO:0042981 335 0.023
cellular catabolic process GO:0044248 295 0.023
rna metabolic process GO:0016070 406 0.023
aging GO:0007568 241 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
negative regulation of metabolic process GO:0009892 331 0.023
secretion GO:0046903 307 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
response to decreased oxygen levels GO:0036293 237 0.023
intracellular transport GO:0046907 185 0.023
metal ion transport GO:0030001 289 0.022
chemical homeostasis GO:0048878 292 0.022
regulation of phosphorylation GO:0042325 248 0.022
macromolecule localization GO:0033036 252 0.022
regeneration GO:0031099 163 0.022
single organism intracellular transport GO:1902582 166 0.022
regulation of neurogenesis GO:0050767 247 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.021
apoptotic process GO:0006915 381 0.021
regulation of signal transduction GO:0009966 318 0.021
neuron development GO:0048666 286 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
cellular homeostasis GO:0019725 252 0.021
cation transmembrane transport GO:0098655 263 0.021
head development GO:0060322 247 0.021
programmed cell death GO:0012501 392 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
purine containing compound metabolic process GO:0072521 253 0.021
regulation of nervous system development GO:0051960 264 0.021
cellular response to organonitrogen compound GO:0071417 197 0.020
response to metal ion GO:0010038 253 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
organic substance catabolic process GO:1901575 316 0.020
ion homeostasis GO:0050801 212 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
regulation of catalytic activity GO:0050790 304 0.020
response to glucocorticoid GO:0051384 223 0.020
regulation of transcription dna templated GO:0006355 374 0.020
brain development GO:0007420 247 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
response to acid chemical GO:0001101 222 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
regulation of protein metabolic process GO:0051246 289 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
ribose phosphate metabolic process GO:0019693 235 0.019
cellular response to stress GO:0033554 269 0.019
rna biosynthetic process GO:0032774 380 0.019
negative regulation of cell communication GO:0010648 158 0.019
neuron projection development GO:0031175 273 0.019
response to carbohydrate GO:0009743 183 0.019
neurological system process GO:0050877 219 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of cellular localization GO:0060341 263 0.019
protein localization GO:0008104 191 0.019
response to ketone GO:1901654 182 0.019
nucleic acid templated transcription GO:0097659 379 0.019
protein oligomerization GO:0051259 191 0.019
regulation of cell differentiation GO:0045595 320 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
cellular component movement GO:0006928 248 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
transcription dna templated GO:0006351 377 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
cellular lipid metabolic process GO:0044255 208 0.018
response to growth factor GO:0070848 189 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
regulation of cell development GO:0060284 263 0.018
response to monosaccharide GO:0034284 159 0.017
response to ethanol GO:0045471 162 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
positive regulation of molecular function GO:0044093 230 0.017
negative regulation of signaling GO:0023057 157 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
response to vitamin GO:0033273 131 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
positive regulation of transport GO:0051050 245 0.017
positive regulation of developmental process GO:0051094 283 0.017
cellular chemical homeostasis GO:0055082 247 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
anterior posterior pattern specification GO:0009952 1 0.017
response to estrogen GO:0043627 232 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
single organism organelle organization GO:1902589 180 0.016
regulation of cell projection organization GO:0031344 175 0.016
gland development GO:0048732 155 0.016
negative regulation of cell death GO:0060548 229 0.016
ras protein signal transduction GO:0007265 29 0.016
multi multicellular organism process GO:0044706 138 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
response to cytokine GO:0034097 215 0.016
positive regulation of gene expression GO:0010628 244 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
behavior GO:0007610 205 0.016
negative regulation of transport GO:0051051 136 0.016
sexual reproduction GO:0019953 148 0.016
response to insulin GO:0032868 133 0.016
proteolysis GO:0006508 175 0.016
nitrogen compound transport GO:0071705 229 0.016
regulation of neuron differentiation GO:0045664 208 0.016
negative regulation of response to stimulus GO:0048585 155 0.015
vesicle mediated transport GO:0016192 181 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of hormone levels GO:0010817 187 0.015
regulation of membrane potential GO:0042391 110 0.015
positive regulation of cell development GO:0010720 176 0.015
blood circulation GO:0008015 183 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
cation homeostasis GO:0055080 195 0.015
regulation of cell proliferation GO:0042127 359 0.015
heart morphogenesis GO:0003007 3 0.015
developmental process involved in reproduction GO:0003006 159 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.014
regulation of neuron projection development GO:0010975 161 0.014
axis specification GO:0009798 4 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
locomotion GO:0040011 237 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
regulation of system process GO:0044057 208 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
circulatory system process GO:0003013 183 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
muscle system process GO:0003012 115 0.014
regulation of protein modification process GO:0031399 194 0.014
growth GO:0040007 165 0.014
positive regulation of nervous system development GO:0051962 178 0.014
defense response GO:0006952 194 0.014
positive regulation of cell communication GO:0010647 271 0.014
carbohydrate metabolic process GO:0005975 130 0.014
chromosome segregation GO:0007059 2 0.014
eye morphogenesis GO:0048592 4 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
response to glucose GO:0009749 136 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
synaptic transmission GO:0007268 235 0.014
gastrulation GO:0007369 2 0.014
response to bacterium GO:0009617 200 0.014
positive regulation of phosphorylation GO:0042327 177 0.013
female pregnancy GO:0007565 122 0.013
secretion by cell GO:0032940 248 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
response to hexose GO:0009746 144 0.013
negative regulation of innate immune response GO:0045824 4 0.013
regulation of anatomical structure size GO:0090066 135 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
positive regulation of cell death GO:0010942 184 0.013
gamete generation GO:0007276 124 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
negative regulation of molecular function GO:0044092 133 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
response to oxidative stress GO:0006979 186 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
positive regulation of signaling GO:0023056 270 0.013
response to other organism GO:0051707 220 0.013
regulation of secretion GO:0051046 224 0.013
response to biotic stimulus GO:0009607 226 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
response to external biotic stimulus GO:0043207 221 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
sex differentiation GO:0007548 113 0.013
metal ion homeostasis GO:0055065 186 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
immune system process GO:0002376 204 0.013
response to toxic substance GO:0009636 133 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
rhythmic process GO:0048511 156 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
cellular cation homeostasis GO:0030003 180 0.013
organic acid transport GO:0015849 116 0.013
oxidation reduction process GO:0055114 304 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
negative regulation of gene expression GO:0010629 199 0.012
establishment of protein localization GO:0045184 141 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
cellular macromolecule localization GO:0070727 122 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
heterocycle catabolic process GO:0046700 167 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
cell projection morphogenesis GO:0048858 123 0.012
cofactor metabolic process GO:0051186 95 0.012
cell cell signaling GO:0007267 335 0.012
positive regulation of protein modification process GO:0031401 142 0.012
positive regulation of signal transduction GO:0009967 175 0.012
cellular component morphogenesis GO:0032989 155 0.012
response to wounding GO:0009611 254 0.012
protein transport GO:0015031 132 0.012
cell migration GO:0016477 197 0.012
cellular ion homeostasis GO:0006873 184 0.012
response to lipopolysaccharide GO:0032496 191 0.012
single organism cellular localization GO:1902580 102 0.012
regulation of ion transport GO:0043269 245 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
response to estradiol GO:0032355 164 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
regulation of secretion by cell GO:1903530 208 0.012
cell part morphogenesis GO:0032990 123 0.012
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.012
cell morphogenesis GO:0000902 142 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
cytoplasmic transport GO:0016482 115 0.012
localization of cell GO:0051674 202 0.012
cellular response to peptide GO:1901653 133 0.012
response to radiation GO:0009314 137 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
aromatic compound catabolic process GO:0019439 168 0.012
lipid storage GO:0019915 1 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
regulation of transferase activity GO:0051338 123 0.011
spindle organization GO:0007051 2 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
tissue development GO:0009888 252 0.011
nucleoside metabolic process GO:0009116 179 0.011
neuron projection morphogenesis GO:0048812 122 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
negative regulation of secretion GO:0051048 82 0.011
regulation of neuron death GO:1901214 115 0.011
response to alkaloid GO:0043279 132 0.011
organophosphate catabolic process GO:0046434 148 0.011
male gamete generation GO:0048232 99 0.011
coenzyme metabolic process GO:0006732 86 0.011
transmission of nerve impulse GO:0019226 42 0.011
liver development GO:0001889 90 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
cell motility GO:0048870 202 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
gonad development GO:0008406 104 0.011
organ regeneration GO:0031100 101 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
spermatogenesis GO:0007283 99 0.011
inflammatory response GO:0006954 150 0.011
membrane organization GO:0061024 94 0.011
nucleotide catabolic process GO:0009166 139 0.011
hepaticobiliary system development GO:0061008 90 0.011
cellular response to lipid GO:0071396 201 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
action potential GO:0001508 54 0.011
response to reactive oxygen species GO:0000302 120 0.011
divalent inorganic cation transport GO:0072511 134 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.010
response to purine containing compound GO:0014074 126 0.010
sequestering of metal ion GO:0051238 9 0.010
carboxylic acid transport GO:0046942 115 0.010
cellular response to insulin stimulus GO:0032869 81 0.010
development of primary sexual characteristics GO:0045137 107 0.010
small molecule biosynthetic process GO:0044283 124 0.010
calcium ion transport GO:0006816 131 0.010
rna localization GO:0006403 4 0.010
sensory perception GO:0007600 101 0.010
cellular protein localization GO:0034613 122 0.010
calcium ion homeostasis GO:0055074 162 0.010
cellular response to alcohol GO:0097306 87 0.010
cell type specific apoptotic process GO:0097285 134 0.010
cell cycle GO:0007049 101 0.010
neuron death GO:0070997 127 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
cell growth GO:0016049 104 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
single organism membrane organization GO:0044802 74 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010

Galc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
disease of metabolism DOID:0014667 0 0.018
central nervous system disease DOID:331 0 0.016
musculoskeletal system disease DOID:17 0 0.015
sensory system disease DOID:0050155 0 0.014
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
inherited metabolic disorder DOID:655 0 0.011