Rattus norvegicus

55 known processes

Cpe

carboxypeptidase E

(Aliases: Cph,MGC93638,CARBE)

Cpe biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of multicellular organismal process GO:0051241 203 0.152
response to metal ion GO:0010038 253 0.121
apoptotic process GO:0006915 381 0.084
positive regulation of signaling GO:0023056 270 0.078
ion transmembrane transport GO:0034220 365 0.077
regulation of programmed cell death GO:0043067 341 0.071
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.071
negative regulation of cell development GO:0010721 82 0.067
regulation of cellular component organization GO:0051128 368 0.060
organic acid metabolic process GO:0006082 292 0.059
regulation of apoptotic process GO:0042981 335 0.057
ras protein signal transduction GO:0007265 29 0.055
intracellular transport GO:0046907 185 0.055
nucleoside phosphate metabolic process GO:0006753 283 0.054
response to peptide GO:1901652 292 0.054
regulation of neurogenesis GO:0050767 247 0.052
nitrogen compound transport GO:0071705 229 0.052
oxoacid metabolic process GO:0043436 290 0.051
cation transport GO:0006812 382 0.051
response to inorganic substance GO:0010035 377 0.050
inorganic ion transmembrane transport GO:0098660 229 0.049
response to corticosteroid GO:0031960 235 0.049
behavior GO:0007610 205 0.049
organophosphate biosynthetic process GO:0090407 143 0.048
macromolecular complex assembly GO:0065003 273 0.048
inorganic cation transmembrane transport GO:0098662 202 0.047
response to wounding GO:0009611 254 0.047
regulation of cell proliferation GO:0042127 359 0.047
response to cadmium ion GO:0046686 35 0.047
negative regulation of gene expression GO:0010629 199 0.045
positive regulation of response to stimulus GO:0048584 285 0.044
regulation of locomotion GO:0040012 148 0.044
action potential GO:0001508 54 0.044
regulation of nervous system development GO:0051960 264 0.043
regulation of ion transport GO:0043269 245 0.043
cell motility GO:0048870 202 0.040
positive regulation of transport GO:0051050 245 0.040
carboxylic acid metabolic process GO:0019752 289 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.039
response to carbohydrate GO:0009743 183 0.039
programmed cell death GO:0012501 392 0.038
positive regulation of phosphate metabolic process GO:0045937 262 0.038
regulation of multicellular organismal development GO:2000026 376 0.036
positive regulation of signal transduction GO:0009967 175 0.036
nucleic acid templated transcription GO:0097659 379 0.035
positive regulation of cellular component organization GO:0051130 200 0.035
cellular response to growth factor stimulus GO:0071363 162 0.035
response to biotic stimulus GO:0009607 226 0.035
circulatory system development GO:0072359 134 0.035
cellular component movement GO:0006928 248 0.035
cation transmembrane transport GO:0098655 263 0.035
nucleotide metabolic process GO:0009117 279 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.034
membrane depolarization during action potential GO:0086010 1 0.033
negative regulation of apoptotic process GO:0043066 181 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
cellular response to organic cyclic compound GO:0071407 202 0.033
regulation of transcription dna templated GO:0006355 374 0.033
protein complex subunit organization GO:0071822 302 0.032
carbohydrate derivative biosynthetic process GO:1901137 124 0.032
tissue development GO:0009888 252 0.032
transmembrane transport GO:0055085 412 0.032
protein phosphorylation GO:0006468 345 0.032
secretion GO:0046903 307 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
secretion by cell GO:0032940 248 0.031
divalent inorganic cation transport GO:0072511 134 0.031
positive regulation of programmed cell death GO:0043068 157 0.031
macromolecular complex subunit organization GO:0043933 339 0.031
intracellular signal transduction GO:0035556 314 0.031
metal ion transport GO:0030001 289 0.031
negative regulation of developmental process GO:0051093 125 0.031
regulation of cell differentiation GO:0045595 320 0.030
regulation of cellular component movement GO:0051270 150 0.030
defense response GO:0006952 194 0.030
negative regulation of nervous system development GO:0051961 79 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
regulation of transmembrane transport GO:0034762 122 0.030
positive regulation of cell communication GO:0010647 271 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
regulation of protein metabolic process GO:0051246 289 0.029
immune system process GO:0002376 204 0.028
protein complex biogenesis GO:0070271 263 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
cellular component assembly GO:0022607 360 0.028
regulation of catalytic activity GO:0050790 304 0.028
regulation of cell migration GO:0030334 128 0.028
cellular amine metabolic process GO:0044106 38 0.028
regulation of transmembrane transporter activity GO:0022898 49 0.028
positive regulation of neurogenesis GO:0050769 165 0.028
response to nutrient levels GO:0031667 370 0.027
response to nutrient GO:0007584 248 0.027
vesicle mediated transport GO:0016192 181 0.027
cellular component biogenesis GO:0044085 368 0.026
rna biosynthetic process GO:0032774 380 0.026
response to ethanol GO:0045471 162 0.026
response to growth factor GO:0070848 189 0.025
regulation of transporter activity GO:0032409 50 0.025
single organism biosynthetic process GO:0044711 342 0.025
response to transition metal nanoparticle GO:1990267 122 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
ribose phosphate biosynthetic process GO:0046390 87 0.025
cellular response to hormone stimulus GO:0032870 247 0.025
amine metabolic process GO:0009308 38 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.024
ribonucleotide biosynthetic process GO:0009260 85 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
cellular response to organonitrogen compound GO:0071417 197 0.024
response to camp GO:0051591 91 0.024
positive regulation of gene expression GO:0010628 244 0.024
response to other organism GO:0051707 220 0.023
regulation of cell development GO:0060284 263 0.023
response to lipopolysaccharide GO:0032496 191 0.023
locomotion GO:0040011 237 0.023
purine containing compound biosynthetic process GO:0072522 85 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
regulation of rna metabolic process GO:0051252 391 0.023
response to bacterium GO:0009617 200 0.023
regulation of cell motility GO:2000145 131 0.023
response to cytokine GO:0034097 215 0.023
ion homeostasis GO:0050801 212 0.023
regulation of molecular function GO:0065009 398 0.023
cellular ketone metabolic process GO:0042180 51 0.023
response to acid chemical GO:0001101 222 0.023
response to glucocorticoid GO:0051384 223 0.022
positive regulation of secretion GO:0051047 140 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
positive regulation of developmental process GO:0051094 283 0.022
regulation of cell projection organization GO:0031344 175 0.022
positive regulation of apoptotic process GO:0043065 154 0.022
cellular lipid metabolic process GO:0044255 208 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.021
cell cell signaling GO:0007267 335 0.021
cellular ion homeostasis GO:0006873 184 0.021
negative regulation of metabolic process GO:0009892 331 0.021
positive regulation of nervous system development GO:0051962 178 0.021
positive regulation of multicellular organismal process GO:0051240 387 0.021
protein complex assembly GO:0006461 263 0.021
divalent metal ion transport GO:0070838 132 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
chemical homeostasis GO:0048878 292 0.021
central nervous system development GO:0007417 311 0.021
negative regulation of cell proliferation GO:0008285 119 0.021
negative regulation of cell death GO:0060548 229 0.021
positive regulation of catalytic activity GO:0043085 184 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
regulation of secretion GO:0051046 224 0.020
positive regulation of cell development GO:0010720 176 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
lipid metabolic process GO:0006629 283 0.020
localization of cell GO:0051674 202 0.020
immune response GO:0006955 104 0.020
response to amine GO:0014075 46 0.020
protein localization GO:0008104 191 0.020
regulation of protein modification process GO:0031399 194 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
organophosphate metabolic process GO:0019637 370 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
nucleoside phosphate biosynthetic process GO:1901293 102 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
response to external biotic stimulus GO:0043207 221 0.019
regulation of neuron differentiation GO:0045664 208 0.019
negative regulation of neuron differentiation GO:0045665 62 0.019
cellular macromolecule localization GO:0070727 122 0.019
gliogenesis GO:0042063 93 0.019
respiratory system development GO:0060541 45 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
response to monosaccharide GO:0034284 159 0.019
homeostatic process GO:0042592 331 0.019
peptidyl amino acid modification GO:0018193 126 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
response to extracellular stimulus GO:0009991 380 0.018
peptidyl tyrosine modification GO:0018212 72 0.018
purine containing compound metabolic process GO:0072521 253 0.018
transcription dna templated GO:0006351 377 0.018
calcium ion transport GO:0006816 131 0.018
purine ribonucleotide biosynthetic process GO:0009152 81 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
monosaccharide metabolic process GO:0005996 61 0.017
positive regulation of molecular function GO:0044093 230 0.017
catabolic process GO:0009056 351 0.017
sensory organ development GO:0007423 74 0.017
regulation of response to wounding GO:1903034 69 0.017
single organism carbohydrate metabolic process GO:0044723 118 0.017
multi organism reproductive process GO:0044703 262 0.017
cellular homeostasis GO:0019725 252 0.017
cardiovascular system development GO:0072358 134 0.017
glial cell differentiation GO:0010001 65 0.017
cell projection organization GO:0030030 302 0.017
adult locomotory behavior GO:0008344 4 0.017
proteolysis GO:0006508 175 0.016
neurological system process GO:0050877 219 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
macromolecule localization GO:0033036 252 0.016
response to amphetamine GO:0001975 25 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
calcium ion transmembrane transport GO:0070588 70 0.016
cellular cation homeostasis GO:0030003 180 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
regulation of membrane potential GO:0042391 110 0.016
response to hypoxia GO:0001666 231 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
cellular protein localization GO:0034613 122 0.016
muscle system process GO:0003012 115 0.016
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
negative regulation of cell differentiation GO:0045596 99 0.015
neuron differentiation GO:0030182 368 0.015
rna metabolic process GO:0016070 406 0.015
regulation of calcium ion transmembrane transport GO:1903169 18 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
negative regulation of biosynthetic process GO:0009890 168 0.014
calcium ion homeostasis GO:0055074 162 0.014
head development GO:0060322 247 0.014
transmission of nerve impulse GO:0019226 42 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
cell migration GO:0016477 197 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
positive regulation of cell death GO:0010942 184 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
salivary gland morphogenesis GO:0007435 1 0.014
amino acid transport GO:0006865 70 0.014
cation homeostasis GO:0055080 195 0.014
salivary gland development GO:0007431 3 0.014
multicellular organism reproduction GO:0032504 233 0.014
positive regulation of lipid kinase activity GO:0090218 2 0.014
neuron development GO:0048666 286 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
hormone secretion GO:0046879 115 0.014
peptidyl tyrosine phosphorylation GO:0018108 72 0.014
cell adhesion GO:0007155 110 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
reproductive process GO:0022414 372 0.014
protein oligomerization GO:0051259 191 0.013
metal ion homeostasis GO:0055065 186 0.013
regulation of phosphorylation GO:0042325 248 0.013
multicellular organismal signaling GO:0035637 44 0.013
regulation of neuron projection development GO:0010975 161 0.013
gland development GO:0048732 155 0.013
histamine secretion involved in inflammatory response GO:0002441 3 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
regeneration GO:0031099 163 0.013
maintenance of location GO:0051235 17 0.013
biological adhesion GO:0022610 110 0.013
response to peptide hormone GO:0043434 278 0.013
cellular chemical homeostasis GO:0055082 247 0.013
protein transport GO:0015031 132 0.013
single organism behavior GO:0044708 130 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
organelle organization GO:0006996 266 0.013
organic anion transport GO:0015711 132 0.013
single organism intracellular transport GO:1902582 166 0.013
organophosphate catabolic process GO:0046434 148 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
single organism cellular localization GO:1902580 102 0.013
neuronal action potential GO:0019228 35 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
regulation of high voltage gated calcium channel activity GO:1901841 3 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
carboxylic acid transport GO:0046942 115 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
embryonic pattern specification GO:0009880 1 0.012
single organism organelle organization GO:1902589 180 0.012
negative regulation of neuron projection development GO:0010977 46 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
inflammatory response GO:0006954 150 0.012
regulation of ras protein signal transduction GO:0046578 45 0.012
signal release GO:0023061 145 0.012
regulation of calcium ion transport GO:0051924 77 0.012
neuron projection development GO:0031175 273 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
single organism catabolic process GO:0044712 283 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
hormone transport GO:0009914 121 0.012
regulation of signal transduction GO:0009966 318 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
chromosome segregation GO:0007059 2 0.012
response to vitamin GO:0033273 131 0.012
brain development GO:0007420 247 0.012
actin cytoskeleton organization GO:0030036 73 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
circulatory system process GO:0003013 183 0.012
multi multicellular organism process GO:0044706 138 0.011
positive regulation of peptide secretion GO:0002793 52 0.011
regulation of metal ion transport GO:0010959 118 0.011
sex differentiation GO:0007548 113 0.011
response to glucose GO:0009749 136 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
regulation of system process GO:0044057 208 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
response to hexose GO:0009746 144 0.011
regulation of cellular localization GO:0060341 263 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
reproductive system development GO:0061458 128 0.011
epithelial cell differentiation GO:0030855 71 0.011
rho protein signal transduction GO:0007266 11 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
organic acid transport GO:0015849 116 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
heart development GO:0007507 72 0.011
response to insulin GO:0032868 133 0.011
histamine secretion by mast cell GO:0002553 3 0.011
actin filament based process GO:0030029 86 0.011
carbohydrate metabolic process GO:0005975 130 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
heterocycle catabolic process GO:0046700 167 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
purine containing compound catabolic process GO:0072523 138 0.011
regulation of peptide transport GO:0090087 87 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
establishment of protein localization GO:0045184 141 0.010
response to lead ion GO:0010288 33 0.010
anion transport GO:0006820 178 0.010
sodium ion transmembrane transport GO:0035725 67 0.010
response to calcium ion GO:0051592 59 0.010
regulation of sister chromatid segregation GO:0033045 1 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
ossification GO:0001503 70 0.010
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.010
heart morphogenesis GO:0003007 3 0.010
response to purine containing compound GO:0014074 126 0.010
multicellular organism growth GO:0035264 1 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.010

Cpe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
sensory system disease DOID:0050155 0 0.018
retinal disease DOID:5679 0 0.017
retinal degeneration DOID:8466 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
central nervous system disease DOID:331 0 0.011
brain disease DOID:936 0 0.010