Rattus norvegicus

0 known processes

Cpz

carboxypeptidase Z

Cpz biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to corticosteroid GO:0031960 235 0.307
kidney development GO:0001822 67 0.249
immune system process GO:0002376 204 0.238
response to inorganic substance GO:0010035 377 0.153
response to oxygen levels GO:0070482 265 0.142
wound healing GO:0042060 122 0.139
macromolecular complex subunit organization GO:0043933 339 0.132
positive regulation of response to stimulus GO:0048584 285 0.122
response to glucocorticoid GO:0051384 223 0.122
central nervous system development GO:0007417 311 0.120
anatomical structure morphogenesis GO:0009653 298 0.120
cellular response to endogenous stimulus GO:0071495 377 0.115
aging GO:0007568 241 0.114
cellular response to oxygen containing compound GO:1901701 386 0.110
skeletal system development GO:0001501 41 0.108
renal system development GO:0072001 67 0.104
cellular response to cytokine stimulus GO:0071345 127 0.103
Rat
response to wounding GO:0009611 254 0.099
cellular response to peptide hormone stimulus GO:0071375 120 0.098
macromolecular complex assembly GO:0065003 273 0.096
regulation of signal transduction GO:0009966 318 0.095
embryonic skeletal system development GO:0048706 3 0.093
cellular response to hormone stimulus GO:0032870 247 0.093
cardiovascular system development GO:0072358 134 0.087
intracellular signal transduction GO:0035556 314 0.083
response to metal ion GO:0010038 253 0.081
response to acid chemical GO:0001101 222 0.081
response to peptide hormone GO:0043434 278 0.081
negative regulation of multicellular organismal process GO:0051241 203 0.080
response to peptide GO:1901652 292 0.080
positive regulation of transport GO:0051050 245 0.079
response to monosaccharide GO:0034284 159 0.079
protein oligomerization GO:0051259 191 0.076
cellular response to nitrogen compound GO:1901699 210 0.073
cellular component assembly GO:0022607 360 0.072
regulation of molecular function GO:0065009 398 0.071
apoptotic process GO:0006915 381 0.071
regulation of cellular localization GO:0060341 263 0.068
positive regulation of developmental process GO:0051094 283 0.067
response to hypoxia GO:0001666 231 0.066
response to decreased oxygen levels GO:0036293 237 0.064
cellular component movement GO:0006928 248 0.063
connective tissue development GO:0061448 33 0.063
cellular response to stress GO:0033554 269 0.062
tissue development GO:0009888 252 0.062
response to nutrient levels GO:0031667 370 0.062
protein localization GO:0008104 191 0.060
vasculature development GO:0001944 70 0.058
protein complex biogenesis GO:0070271 263 0.058
regulation of multicellular organismal development GO:2000026 376 0.057
head development GO:0060322 247 0.057
cellular response to peptide GO:1901653 133 0.055
positive regulation of signal transduction GO:0009967 175 0.055
response to extracellular stimulus GO:0009991 380 0.054
cellular response to acid chemical GO:0071229 75 0.053
response to retinoic acid GO:0032526 63 0.053
reproductive process GO:0022414 372 0.052
cellular component biogenesis GO:0044085 368 0.051
cellular response to vitamin e GO:0071306 3 0.051
urogenital system development GO:0001655 78 0.051
cellular response to organonitrogen compound GO:0071417 197 0.050
response to growth factor GO:0070848 189 0.050
programmed cell death GO:0012501 392 0.050
tissue remodeling GO:0048771 40 0.050
immune response GO:0006955 104 0.049
homeostatic process GO:0042592 331 0.049
response to carbohydrate GO:0009743 183 0.049
response to hexose GO:0009746 144 0.048
gastrulation GO:0007369 2 0.048
response to ketone GO:1901654 182 0.047
neuron development GO:0048666 286 0.047
organ morphogenesis GO:0009887 75 0.047
brain development GO:0007420 247 0.047
positive regulation of molecular function GO:0044093 230 0.045
cellular amide metabolic process GO:0043603 44 0.045
regulation of intracellular signal transduction GO:1902531 218 0.044
macromolecule localization GO:0033036 252 0.044
blood vessel development GO:0001568 69 0.044
developmental process involved in reproduction GO:0003006 159 0.044
regulation of rna metabolic process GO:0051252 391 0.044
response to cytokine GO:0034097 215 0.042
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.042
enzyme linked receptor protein signaling pathway GO:0007167 116 0.041
positive regulation of gene expression GO:0010628 244 0.041
establishment of protein localization GO:0045184 141 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.041
cell projection organization GO:0030030 302 0.039
regulation of anatomical structure morphogenesis GO:0022603 141 0.039
tube development GO:0035295 89 0.039
protein complex assembly GO:0006461 263 0.038
angiogenesis GO:0001525 53 0.038
g protein coupled receptor signaling pathway GO:0007186 242 0.038
response to glucose GO:0009749 136 0.038
catabolic process GO:0009056 351 0.037
organic acid metabolic process GO:0006082 292 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.037
response to toxic substance GO:0009636 133 0.036
neuron differentiation GO:0030182 368 0.036
regulation of apoptotic process GO:0042981 335 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.036
cellular response to retinoic acid GO:0071300 27 0.035
protein complex subunit organization GO:0071822 302 0.035
cellular response to organic cyclic compound GO:0071407 202 0.035
cation transport GO:0006812 382 0.034
artery development GO:0060840 3 0.034
calcium ion homeostasis GO:0055074 162 0.034
secretion by cell GO:0032940 248 0.034
ribose phosphate metabolic process GO:0019693 235 0.033
response to biotic stimulus GO:0009607 226 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
blood circulation GO:0008015 183 0.033
organonitrogen compound biosynthetic process GO:1901566 167 0.033
small gtpase mediated signal transduction GO:0007264 36 0.032
positive regulation of cell death GO:0010942 184 0.032
regulation of cellular component organization GO:0051128 368 0.032
divalent metal ion transport GO:0070838 132 0.032
cell motility GO:0048870 202 0.031
response to estradiol GO:0032355 164 0.031
response to increased oxygen levels GO:0036296 45 0.031
regulation of protein metabolic process GO:0051246 289 0.031
inflammatory response GO:0006954 150 0.031
transmembrane transport GO:0055085 412 0.031
response to estrogen GO:0043627 232 0.030
cellular response to lipid GO:0071396 201 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
response to alkaloid GO:0043279 132 0.030
cellular response to growth factor stimulus GO:0071363 162 0.030
response to external biotic stimulus GO:0043207 221 0.030
negative regulation of developmental process GO:0051093 125 0.029
response to nutrient GO:0007584 248 0.029
nucleic acid templated transcription GO:0097659 379 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.029
response to mineralocorticoid GO:0051385 49 0.029
regulation of secretion GO:0051046 224 0.028
protein heterooligomerization GO:0051291 89 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
oxoacid metabolic process GO:0043436 290 0.028
response to transition metal nanoparticle GO:1990267 122 0.028
regulation of hydrolase activity GO:0051336 143 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
response to radiation GO:0009314 137 0.027
secretion GO:0046903 307 0.027
circulatory system development GO:0072359 134 0.027
response to oxidative stress GO:0006979 186 0.026
kidney mesenchyme development GO:0072074 2 0.026
positive regulation of secretion GO:0051047 140 0.026
cellular homeostasis GO:0019725 252 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
cartilage development GO:0051216 22 0.025
gland development GO:0048732 155 0.025
transcription dna templated GO:0006351 377 0.025
divalent inorganic cation transport GO:0072511 134 0.025
response to lipopolysaccharide GO:0032496 191 0.025
carboxylic acid metabolic process GO:0019752 289 0.025
regulation of b cell differentiation GO:0045577 1 0.024
protein homooligomerization GO:0051260 91 0.024
cellular chemical homeostasis GO:0055082 247 0.024
regulation of catalytic activity GO:0050790 304 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
rna metabolic process GO:0016070 406 0.024
single organism biosynthetic process GO:0044711 342 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
development of primary sexual characteristics GO:0045137 107 0.024
organophosphate metabolic process GO:0019637 370 0.024
eye morphogenesis GO:0048592 4 0.023
proteolysis GO:0006508 175 0.023
sex differentiation GO:0007548 113 0.023
regulation of secretion by cell GO:1903530 208 0.023
regulation of cell proliferation GO:0042127 359 0.023
formation of primary germ layer GO:0001704 1 0.023
cellular component morphogenesis GO:0032989 155 0.023
protein secretion GO:0009306 34 0.023
rna biosynthetic process GO:0032774 380 0.022
cell activation GO:0001775 97 0.022
regulation of hormone levels GO:0010817 187 0.022
positive regulation of cell communication GO:0010647 271 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.022
sequestering of metal ion GO:0051238 9 0.022
cell migration GO:0016477 197 0.021
neuron projection development GO:0031175 273 0.021
response to fluoride GO:1902617 3 0.021
response to hyperoxia GO:0055093 45 0.021
regulation of response to stress GO:0080134 126 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
negative regulation of metabolic process GO:0009892 331 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
protein transport GO:0015031 132 0.021
positive regulation of signaling GO:0023056 270 0.020
limb morphogenesis GO:0035108 4 0.020
regulation of phosphorylation GO:0042325 248 0.020
peptide metabolic process GO:0006518 32 0.020
calcium ion transport GO:0006816 131 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
morphogenesis of an epithelium GO:0002009 20 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
cartilage development involved in endochondral bone morphogenesis GO:0060351 3 0.020
anatomical structure formation involved in morphogenesis GO:0048646 83 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
positive regulation of immune response GO:0050778 42 0.019
regulation of canonical wnt signaling pathway GO:0060828 4 0.019
cellular response to external stimulus GO:0071496 118 0.019
single organism reproductive process GO:0044702 297 0.019
organic substance catabolic process GO:1901575 316 0.019
anterior posterior pattern specification GO:0009952 1 0.019
chemical homeostasis GO:0048878 292 0.019
cellular amine metabolic process GO:0044106 38 0.019
extracellular fibril organization GO:0043206 1 0.019
regulation of immune system process GO:0002682 123 0.018
endochondral bone growth GO:0003416 3 0.018
collagen fibril organization GO:0030199 1 0.018
cell junction maintenance GO:0034331 1 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
response to bacterium GO:0009617 200 0.018
ras protein signal transduction GO:0007265 29 0.018
glucose homeostasis GO:0042593 75 0.018
single organism catabolic process GO:0044712 283 0.018
multicellular organism reproduction GO:0032504 233 0.017
nitrogen compound transport GO:0071705 229 0.017
cognition GO:0050890 92 0.017
ion transmembrane transport GO:0034220 365 0.017
ribonucleotide catabolic process GO:0009261 136 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
positive regulation of secretion by cell GO:1903532 128 0.017
organelle organization GO:0006996 266 0.017
growth plate cartilage development GO:0003417 2 0.017
response to purine containing compound GO:0014074 126 0.017
response to nicotine GO:0035094 51 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
heart morphogenesis GO:0003007 3 0.017
female pregnancy GO:0007565 122 0.017
regeneration GO:0031099 163 0.017
cell type specific apoptotic process GO:0097285 134 0.017
cellular catabolic process GO:0044248 295 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
regulation of programmed cell death GO:0043067 341 0.016
blood vessel morphogenesis GO:0048514 58 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.016
epithelium development GO:0060429 96 0.016
reproduction GO:0000003 245 0.016
cellular response to tumor necrosis factor GO:0071356 46 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
response to other organism GO:0051707 220 0.016
hormone secretion GO:0046879 115 0.016
pro t cell differentiation GO:0002572 1 0.016
purine containing compound metabolic process GO:0072521 253 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
regulation of immune response GO:0050776 55 0.016
cation homeostasis GO:0055080 195 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
cell adhesion GO:0007155 110 0.016
protein heterotrimerization GO:0070208 2 0.016
protein phosphorylation GO:0006468 345 0.016
metal ion transport GO:0030001 289 0.016
nucleotide metabolic process GO:0009117 279 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
response to vitamin GO:0033273 131 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
reproductive structure development GO:0048608 128 0.015
amine metabolic process GO:0009308 38 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
cellular ion homeostasis GO:0006873 184 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
b cell differentiation GO:0030183 2 0.015
multi organism reproductive process GO:0044703 262 0.015
positive regulation of protein transport GO:0051222 41 0.015
regulation of vasculature development GO:1901342 44 0.015
purine ribonucleotide biosynthetic process GO:0009152 81 0.015
response to ethanol GO:0045471 162 0.015
odontogenesis GO:0042476 32 0.015
regulation of cell differentiation GO:0045595 320 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
circulatory system process GO:0003013 183 0.014
vascular process in circulatory system GO:0003018 96 0.014
regulation of calcium ion transport GO:0051924 77 0.014
localization of cell GO:0051674 202 0.014
negative regulation of fibrinolysis GO:0051918 2 0.014
nucleoside metabolic process GO:0009116 179 0.014
signal release GO:0023061 145 0.014
mesoderm development GO:0007498 2 0.014
carbohydrate homeostasis GO:0033500 75 0.014
response to reactive oxygen species GO:0000302 120 0.014
regulation of transcription dna templated GO:0006355 374 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
response to tumor necrosis factor GO:0034612 56 0.014
response to fibroblast growth factor GO:0071774 29 0.014
salivary gland development GO:0007431 3 0.014
cellular response to insulin stimulus GO:0032869 81 0.014
biological adhesion GO:0022610 110 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
cell morphogenesis GO:0000902 142 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
positive regulation of immune system process GO:0002684 90 0.014
negative regulation of cell differentiation GO:0045596 99 0.013
memory GO:0007613 54 0.013
ion homeostasis GO:0050801 212 0.013
reproductive system development GO:0061458 128 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
single organism behavior GO:0044708 130 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
liver development GO:0001889 90 0.013
response to organophosphorus GO:0046683 102 0.013
inner ear receptor cell differentiation GO:0060113 2 0.013
tissue morphogenesis GO:0048729 22 0.013
defense response GO:0006952 194 0.013
response to amino acid GO:0043200 75 0.013
regulation of neuron projection development GO:0010975 161 0.013
morphogenesis of a polarized epithelium GO:0001738 1 0.012
hormone transport GO:0009914 121 0.012
cellular response to carbohydrate stimulus GO:0071322 72 0.012
neurological system process GO:0050877 219 0.012
regulation of locomotion GO:0040012 148 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
regulation of response to external stimulus GO:0032101 106 0.012
response to transforming growth factor beta GO:0071559 46 0.012
cellular cation homeostasis GO:0030003 180 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
muscle organ development GO:0007517 50 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
learning or memory GO:0007611 90 0.012
regulation of cell growth GO:0001558 85 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
locomotion GO:0040011 237 0.012
response to insulin GO:0032868 133 0.012
carbohydrate metabolic process GO:0005975 130 0.012
hormone metabolic process GO:0042445 69 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
cellular response to hexose stimulus GO:0071331 65 0.012
cellular lipid metabolic process GO:0044255 208 0.012
regulation of response to wounding GO:1903034 69 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
cell cell signaling GO:0007267 335 0.012
negative regulation of signaling GO:0023057 157 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
oxidation reduction process GO:0055114 304 0.012
positive regulation of blood coagulation GO:0030194 4 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
negative regulation of neuron death GO:1901215 69 0.012
sexual reproduction GO:0019953 148 0.012
neuron death GO:0070997 127 0.012
monovalent inorganic cation transport GO:0015672 172 0.011
appendage morphogenesis GO:0035107 4 0.011
cellular response to alcohol GO:0097306 87 0.011
cellular response to metal ion GO:0071248 55 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
regulation of protein modification process GO:0031399 194 0.011
regulation of cell projection organization GO:0031344 175 0.011
cellular response to monosaccharide stimulus GO:0071326 67 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
extracellular matrix constituent secretion GO:0070278 4 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
regulation of cell development GO:0060284 263 0.011
sensory organ development GO:0007423 74 0.011
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
cellular ketone metabolic process GO:0042180 51 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.011
regulation of protein localization GO:0032880 81 0.011
response to camp GO:0051591 91 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
organ regeneration GO:0031100 101 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
small molecule biosynthetic process GO:0044283 124 0.011
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
regulation of homeostatic process GO:0032844 101 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
response to temperature stimulus GO:0009266 94 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
metanephric comma shaped body morphogenesis GO:0072278 2 0.011
developmental growth GO:0048589 100 0.011
response to interleukin 1 GO:0070555 55 0.010
negative regulation of cell death GO:0060548 229 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
regulation of map kinase activity GO:0043405 53 0.010
cellular response to oxygen levels GO:0071453 60 0.010
cellular response to nutrient levels GO:0031669 60 0.010
embryonic appendage morphogenesis GO:0035113 4 0.010
response to catecholamine GO:0071869 16 0.010
cellular glucose homeostasis GO:0001678 66 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
metal ion homeostasis GO:0055065 186 0.010
extracellular matrix organization GO:0030198 13 0.010
comma shaped body morphogenesis GO:0072049 2 0.010
growth GO:0040007 165 0.010
tube formation GO:0035148 3 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
islet amyloid polypeptide processing GO:0034231 1 0.010
regulation of neuron death GO:1901214 115 0.010
endocrine system development GO:0035270 30 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
rhythmic process GO:0048511 156 0.010
organophosphate catabolic process GO:0046434 148 0.010
second messenger mediated signaling GO:0019932 51 0.010
regulation of camp metabolic process GO:0030814 43 0.010

Cpz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
musculoskeletal system disease DOID:17 0 0.052
osteochondrodysplasia DOID:2256 0 0.042
bone development disease DOID:0080006 0 0.042
bone disease DOID:0080001 0 0.042
connective tissue disease DOID:65 0 0.042
nervous system disease DOID:863 0 0.036
retinal disease DOID:5679 0 0.017
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.011