Rattus norvegicus

171 known processes

Nkx6-1

NK6 homeobox 1

(Aliases: Nkx61,Nkx6.1,Nkx6a)

Nkx6-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.540
positive regulation of cellular biosynthetic process GO:0031328 295 0.378
positive regulation of biosynthetic process GO:0009891 319 0.274
regulation of rna biosynthetic process GO:2001141 381 0.268
neuron death GO:0070997 127 0.267
cellular component movement GO:0006928 248 0.259
Mouse
rna biosynthetic process GO:0032774 380 0.256
positive regulation of multicellular organismal process GO:0051240 387 0.247
Mouse
regulation of apoptotic process GO:0042981 335 0.235
regulation of rna metabolic process GO:0051252 391 0.232
positive regulation of cell communication GO:0010647 271 0.221
response to peptide hormone GO:0043434 278 0.198
nucleic acid templated transcription GO:0097659 379 0.197
regulation of nucleic acid templated transcription GO:1903506 380 0.196
response to extracellular stimulus GO:0009991 380 0.194
transcription dna templated GO:0006351 377 0.188
rna metabolic process GO:0016070 406 0.186
regulation of hormone levels GO:0010817 187 0.182
cellular response to stress GO:0033554 269 0.176
response to estradiol GO:0032355 164 0.175
response to peptide GO:1901652 292 0.174
positive regulation of intracellular signal transduction GO:1902533 138 0.173
response to cytokine GO:0034097 215 0.171
single organism behavior GO:0044708 130 0.171
response to nutrient levels GO:0031667 370 0.169
defecation GO:0030421 1 0.162
regulation of programmed cell death GO:0043067 341 0.156
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.155
response to biotic stimulus GO:0009607 226 0.152
response to corticosteroid GO:0031960 235 0.152
cellular response to organic cyclic compound GO:0071407 202 0.151
protein complex subunit organization GO:0071822 302 0.149
regulation of transcription dna templated GO:0006355 374 0.149
transcription from rna polymerase ii promoter GO:0006366 252 0.149
amino acid transport GO:0006865 70 0.148
macromolecular complex subunit organization GO:0043933 339 0.145
central nervous system development GO:0007417 311 0.145
Zebrafish Mouse
hormone secretion GO:0046879 115 0.143
positive regulation of response to stimulus GO:0048584 285 0.139
nitrogen compound transport GO:0071705 229 0.139
regulation of signal transduction GO:0009966 318 0.135
brain development GO:0007420 247 0.133
response to inorganic substance GO:0010035 377 0.132
multicellular organism reproduction GO:0032504 233 0.131
Worm
response to radiation GO:0009314 137 0.127
response to tumor necrosis factor GO:0034612 56 0.126
neuron projection morphogenesis GO:0048812 122 0.126
Mouse
cellular response to hormone stimulus GO:0032870 247 0.125
protein oligomerization GO:0051259 191 0.125
response to light stimulus GO:0009416 52 0.125
regulation of neuron death GO:1901214 115 0.124
regulation of phosphorylation GO:0042325 248 0.123
defense response GO:0006952 194 0.121
learning or memory GO:0007611 90 0.119
positive regulation of cell proliferation GO:0008284 249 0.119
hormone transport GO:0009914 121 0.116
regulation of intracellular signal transduction GO:1902531 218 0.115
protein phosphorylation GO:0006468 345 0.115
regulation of muscle contraction GO:0006937 53 0.113
regulation of cellular component movement GO:0051270 150 0.113
Mouse
regulation of secretion GO:0051046 224 0.113
amine transport GO:0015837 57 0.113
cellular response to lipid GO:0071396 201 0.111
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.109
behavior GO:0007610 205 0.108
Worm
cognition GO:0050890 92 0.106
cellular response to abiotic stimulus GO:0071214 85 0.105
neuron neuron synaptic transmission GO:0007270 60 0.104
cellular component assembly GO:0022607 360 0.103
negative regulation of response to stimulus GO:0048585 155 0.103
regulation of phosphorus metabolic process GO:0051174 349 0.102
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.102
regulation of secretion by cell GO:1903530 208 0.101
axon development GO:0061564 96 0.101
Mouse
response to electrical stimulus GO:0051602 56 0.099
cellular response to nitrogen compound GO:1901699 210 0.098
response to estrogen GO:0043627 232 0.094
cell cell signaling GO:0007267 335 0.092
reproduction GO:0000003 245 0.091
Worm
positive regulation of signaling GO:0023056 270 0.090
learning GO:0007612 33 0.088
neurological system process GO:0050877 219 0.087
cellular response to oxygen containing compound GO:1901701 386 0.086
oxidation reduction process GO:0055114 304 0.085
steroid metabolic process GO:0008202 73 0.085
negative regulation of neuron death GO:1901215 69 0.084
cellular response to organonitrogen compound GO:0071417 197 0.083
response to mechanical stimulus GO:0009612 134 0.083
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.082
circadian rhythm GO:0007623 88 0.082
cellular response to external stimulus GO:0071496 118 0.081
negative regulation of macromolecule metabolic process GO:0010605 260 0.080
response to monosaccharide GO:0034284 159 0.079
response to alkaloid GO:0043279 132 0.079
negative regulation of cellular biosynthetic process GO:0031327 161 0.077
ossification GO:0001503 70 0.076
limbic system development GO:0021761 38 0.076
response to acid chemical GO:0001101 222 0.076
single organism biosynthetic process GO:0044711 342 0.075
negative regulation of cellular metabolic process GO:0031324 281 0.075
response to mineralocorticoid GO:0051385 49 0.072
organic anion transport GO:0015711 132 0.072
programmed cell death GO:0012501 392 0.071
muscle contraction GO:0006936 88 0.071
cellular component biogenesis GO:0044085 368 0.071
tube development GO:0035295 89 0.070
response to nutrient GO:0007584 248 0.070
organelle organization GO:0006996 266 0.070
cellular response to cytokine stimulus GO:0071345 127 0.069
negative regulation of metabolic process GO:0009892 331 0.068
cellular ketone metabolic process GO:0042180 51 0.067
neuropeptide signaling pathway GO:0007218 29 0.065
hippocampus development GO:0021766 30 0.065
negative regulation of cell differentiation GO:0045596 99 0.064
Mouse
protein homooligomerization GO:0051260 91 0.064
intracellular signal transduction GO:0035556 314 0.064
jak stat cascade GO:0007259 26 0.064
negative regulation of cell death GO:0060548 229 0.064
positive regulation of cell death GO:0010942 184 0.063
reproductive process GO:0022414 372 0.063
Worm
chemical homeostasis GO:0048878 292 0.062
regulation of nervous system development GO:0051960 264 0.061
Mouse
positive regulation of programmed cell death GO:0043068 157 0.061
response to hexose GO:0009746 144 0.061
regulation of phosphate metabolic process GO:0019220 349 0.061
regulation of amine transport GO:0051952 54 0.061
response to bacterium GO:0009617 200 0.060
regulation of cellular localization GO:0060341 263 0.060
multicellular organismal reproductive process GO:0048609 233 0.060
Worm
anatomical structure morphogenesis GO:0009653 298 0.060
Mouse
response to wounding GO:0009611 254 0.059
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.059
positive regulation of transport GO:0051050 245 0.059
response to glucocorticoid GO:0051384 223 0.058
feeding behavior GO:0007631 53 0.058
neuron projection development GO:0031175 273 0.057
Mouse
muscle system process GO:0003012 115 0.056
response to carbohydrate GO:0009743 183 0.056
regulation of cellular component organization GO:0051128 368 0.055
Mouse
cell part morphogenesis GO:0032990 123 0.055
Mouse
single organism carbohydrate metabolic process GO:0044723 118 0.055
tissue development GO:0009888 252 0.055
response to ammonium ion GO:0060359 71 0.054
positive regulation of phosphate metabolic process GO:0045937 262 0.054
regulation of system process GO:0044057 208 0.053
immune effector process GO:0002252 53 0.053
homeostatic process GO:0042592 331 0.052
pallium development GO:0021543 42 0.052
developmental process involved in reproduction GO:0003006 159 0.052
Worm
cell migration GO:0016477 197 0.051
Mouse
response to cocaine GO:0042220 39 0.051
negative regulation of transport GO:0051051 136 0.051
anion transport GO:0006820 178 0.051
regulation of molecular function GO:0065009 398 0.050
regulation of defense response GO:0031347 68 0.050
cell projection morphogenesis GO:0048858 123 0.050
Mouse
negative regulation of rna biosynthetic process GO:1902679 118 0.050
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.050
organic acid transport GO:0015849 116 0.050
response to amine GO:0014075 46 0.050
locomotory exploration behavior GO:0035641 1 0.049
rhythmic process GO:0048511 156 0.049
regulation of catalytic activity GO:0050790 304 0.049
positive regulation of signal transduction GO:0009967 175 0.048
regulation of response to stress GO:0080134 126 0.048
response to glucose GO:0009749 136 0.047
localization of cell GO:0051674 202 0.047
Mouse
cellular chemical homeostasis GO:0055082 247 0.047
negative regulation of rna metabolic process GO:0051253 123 0.047
positive regulation of apoptotic process GO:0043065 154 0.046
positive regulation of rna biosynthetic process GO:1902680 197 0.046
regulation of multicellular organismal development GO:2000026 376 0.045
Mouse
cytokine production GO:0001816 61 0.045
negative regulation of biosynthetic process GO:0009890 168 0.045
associative learning GO:0008306 19 0.045
positive regulation of nucleic acid templated transcription GO:1903508 197 0.045
positive regulation of phosphorylation GO:0042327 177 0.045
response to growth factor GO:0070848 189 0.045
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.045
g protein coupled receptor signaling pathway GO:0007186 242 0.045
protein localization GO:0008104 191 0.044
cellular response to growth factor stimulus GO:0071363 162 0.044
locomotion GO:0040011 237 0.044
Mouse
signal release GO:0023061 145 0.044
regulation of heart contraction GO:0008016 48 0.043
positive regulation of phosphorus metabolic process GO:0010562 262 0.043
muscle structure development GO:0061061 87 0.043
macromolecule localization GO:0033036 252 0.042
negative regulation of cell proliferation GO:0008285 119 0.042
regulation of cell proliferation GO:0042127 359 0.042
response to external biotic stimulus GO:0043207 221 0.042
negative regulation of secretion GO:0051048 82 0.041
regulation of synaptic plasticity GO:0048167 70 0.041
positive regulation of rna metabolic process GO:0051254 203 0.041
positive regulation of protein metabolic process GO:0051247 178 0.040
organic substance catabolic process GO:1901575 316 0.040
gastrulation GO:0007369 2 0.040
response to hydrogen peroxide GO:0042542 89 0.040
protein transport GO:0015031 132 0.040
hormone metabolic process GO:0042445 69 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.040
circulatory system development GO:0072359 134 0.040
inflammatory response GO:0006954 150 0.039
macromolecular complex assembly GO:0065003 273 0.039
multicellular organismal homeostasis GO:0048871 49 0.039
positive regulation of transcription dna templated GO:0045893 197 0.039
cellular response to peptide hormone stimulus GO:0071375 120 0.039
peptidyl tyrosine phosphorylation GO:0018108 72 0.039
negative regulation of gene expression GO:0010629 199 0.038
growth GO:0040007 165 0.038
Mouse
steroid biosynthetic process GO:0006694 48 0.038
cellular response to steroid hormone stimulus GO:0071383 93 0.038
chemotaxis GO:0006935 66 0.037
protein complex assembly GO:0006461 263 0.037
positive regulation of molecular function GO:0044093 230 0.037
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.037
cellular response to peptide GO:1901653 133 0.037
cellular response to acid chemical GO:0071229 75 0.037
regulation of norepinephrine secretion GO:0014061 15 0.037
embryo development GO:0009790 49 0.036
ovulation cycle GO:0042698 67 0.036
multi organism reproductive process GO:0044703 262 0.036
Worm
regulation of cell migration GO:0030334 128 0.036
Mouse
synaptic transmission GO:0007268 235 0.036
positive regulation of serotonin secretion GO:0014064 1 0.036
motor neuron axon guidance GO:0008045 1 0.035
positive regulation of secretion GO:0051047 140 0.035
apoptotic process GO:0006915 381 0.035
peptide secretion GO:0002790 86 0.035
regulation of ion transport GO:0043269 245 0.035
regulation of lipid metabolic process GO:0019216 68 0.035
regulation of cell motility GO:2000145 131 0.035
Mouse
negative regulation of programmed cell death GO:0043069 183 0.033
regulation of response to wounding GO:1903034 69 0.033
positive regulation of peptide hormone secretion GO:0090277 50 0.033
response to reactive oxygen species GO:0000302 120 0.033
regulation of vasculature development GO:1901342 44 0.033
negative regulation of defense response GO:0031348 19 0.033
response to ketone GO:1901654 182 0.033
leukocyte activation GO:0045321 76 0.033
response to fatty acid GO:0070542 65 0.032
response to purine containing compound GO:0014074 126 0.032
catabolic process GO:0009056 351 0.032
aging GO:0007568 241 0.032
developmental growth GO:0048589 100 0.032
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.032
cellular response to oxidative stress GO:0034599 76 0.032
negative regulation of defecation GO:2000293 1 0.032
positive regulation of gene expression GO:0010628 244 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.032
positive regulation of developmental process GO:0051094 283 0.031
Mouse
response to oxygen levels GO:0070482 265 0.031
regulation of growth GO:0040008 105 0.031
Mouse
regulation of blood circulation GO:1903522 110 0.031
carbohydrate metabolic process GO:0005975 130 0.031
regulation of endocrine process GO:0044060 21 0.031
sensory perception of pain GO:0019233 73 0.031
response to lipopolysaccharide GO:0032496 191 0.031
cell adhesion GO:0007155 110 0.030
negative regulation of signaling GO:0023057 157 0.030
regulation of ossification GO:0030278 32 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.030
negative regulation of nucleic acid templated transcription GO:1903507 117 0.030
carboxylic acid metabolic process GO:0019752 289 0.030
single organism reproductive process GO:0044702 297 0.030
Worm
sensory perception GO:0007600 101 0.030
memory GO:0007613 54 0.030
single organism cellular localization GO:1902580 102 0.030
regulation of cell differentiation GO:0045595 320 0.030
Mouse
regulation of protein metabolic process GO:0051246 289 0.030
synapse assembly GO:0007416 29 0.030
cellular carbohydrate metabolic process GO:0044262 72 0.029
forebrain development GO:0030900 98 0.029
immune response GO:0006955 104 0.029
negative regulation of neuron apoptotic process GO:0043524 45 0.029
signal transduction by phosphorylation GO:0023014 144 0.029
cell morphogenesis involved in differentiation GO:0000904 119 0.029
Mouse
regulation of catecholamine secretion GO:0050433 32 0.029
secretion by cell GO:0032940 248 0.029
response to organophosphorus GO:0046683 102 0.029
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.029
negative regulation of response to wounding GO:1903035 23 0.028
peptidyl amino acid modification GO:0018193 126 0.028
cellular response to tumor necrosis factor GO:0071356 46 0.028
single organism intracellular transport GO:1902582 166 0.028
cellular homeostasis GO:0019725 252 0.028
striated muscle contraction GO:0006941 44 0.028
positive regulation of blood circulation GO:1903524 65 0.028
regulation of blood vessel size GO:0050880 89 0.028
negative regulation of ion transport GO:0043271 51 0.028
purine nucleoside monophosphate catabolic process GO:0009128 55 0.028
positive regulation of synaptic transmission GO:0050806 62 0.027
response to transition metal nanoparticle GO:1990267 122 0.027
response to metal ion GO:0010038 253 0.027
cell type specific apoptotic process GO:0097285 134 0.027
response to temperature stimulus GO:0009266 94 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.027
neuron differentiation GO:0030182 368 0.027
Zebrafish Mouse
exploration behavior GO:0035640 1 0.027
head development GO:0060322 247 0.027
regulation of neuron apoptotic process GO:0043523 83 0.026
telencephalon development GO:0021537 62 0.026
negative regulation of calcium ion import GO:0090281 2 0.026
glucose homeostasis GO:0042593 75 0.026
peptide transport GO:0015833 97 0.026
cell morphogenesis GO:0000902 142 0.026
Mouse
regulation of anion transport GO:0044070 43 0.026
response to hypoxia GO:0001666 231 0.026
monoamine transport GO:0015844 43 0.026
ion homeostasis GO:0050801 212 0.025
cellular protein localization GO:0034613 122 0.025
actin filament based movement GO:0030048 16 0.025
cellular macromolecule localization GO:0070727 122 0.025
regulation of transmembrane transport GO:0034762 122 0.025
response to ethanol GO:0045471 162 0.025
regulation of protein modification process GO:0031399 194 0.025
sex differentiation GO:0007548 113 0.025
Worm
olfactory learning GO:0008355 1 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.025
cellular catabolic process GO:0044248 295 0.025
anatomical structure formation involved in morphogenesis GO:0048646 83 0.024
positive regulation of neurogenesis GO:0050769 165 0.024
Mouse
epithelium development GO:0060429 96 0.024
regulation of homotypic cell cell adhesion GO:0034110 4 0.024
carboxylic acid transport GO:0046942 115 0.024
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.024
acid secretion GO:0046717 48 0.024
positive regulation of camp metabolic process GO:0030816 31 0.024
axon guidance GO:0007411 24 0.024
anterior posterior pattern specification GO:0009952 1 0.024
second messenger mediated signaling GO:0019932 51 0.023
regulation of immune response GO:0050776 55 0.023
renal system development GO:0072001 67 0.023
response to blue light GO:0009637 1 0.023
regulation of muscle system process GO:0090257 79 0.023
urogenital system development GO:0001655 78 0.023
regulation of defecation GO:2000292 1 0.023
cell activation GO:0001775 97 0.023
cellular nitrogen compound catabolic process GO:0044270 163 0.023
regulation of excretion GO:0044062 21 0.023
taxis GO:0042330 67 0.023
positive regulation of ion transport GO:0043270 94 0.023
multicellular organismal response to stress GO:0033555 25 0.023
l glutamate import GO:0051938 2 0.023
cation transmembrane transport GO:0098655 263 0.023
response to nicotine GO:0035094 51 0.023
single organism membrane organization GO:0044802 74 0.023
cellular response to biotic stimulus GO:0071216 59 0.022
synaptic transmission gabaergic GO:0051932 22 0.022
single organism organelle organization GO:1902589 180 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
urinary bladder smooth muscle contraction GO:0014832 4 0.022
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.022
digestive system development GO:0055123 41 0.022
positive regulation of saliva secretion GO:0046878 3 0.022
muscle tissue development GO:0060537 58 0.022
organ morphogenesis GO:0009887 75 0.022
limb morphogenesis GO:0035108 4 0.022
development of primary sexual characteristics GO:0045137 107 0.022
Worm
regulation of inflammatory response GO:0050727 48 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
carbohydrate homeostasis GO:0033500 75 0.021
peptidyl tyrosine modification GO:0018212 72 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
Mouse
protein complex biogenesis GO:0070271 263 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
Mouse
positive regulation of growth GO:0045927 55 0.021
cellular response to extracellular stimulus GO:0031668 73 0.021
cytoskeleton organization GO:0007010 111 0.021
regulation of cell activation GO:0050865 50 0.021
regulation of leukocyte activation GO:0002694 45 0.021
neuron projection guidance GO:0097485 24 0.021
neurotransmitter gated ion channel clustering GO:0072578 3 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
regulation of response to external stimulus GO:0032101 106 0.020
long term synaptic potentiation GO:0060291 21 0.020
protein localization to membrane GO:0072657 36 0.020
monosaccharide metabolic process GO:0005996 61 0.020
negative regulation of neurogenesis GO:0050768 78 0.020
Mouse
heart contraction GO:0060047 57 0.020
axonogenesis GO:0007409 71 0.020
Mouse
intracellular transport GO:0046907 185 0.020
gliogenesis GO:0042063 93 0.020
Mouse
single organism catabolic process GO:0044712 283 0.020
endocrine hormone secretion GO:0060986 21 0.020
immune system process GO:0002376 204 0.019
small molecule biosynthetic process GO:0044283 124 0.019
regulation of homeostatic process GO:0032844 101 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
regulation of lipid biosynthetic process GO:0046890 38 0.019
epinephrine secretion GO:0048242 6 0.019
positive regulation of lipid metabolic process GO:0045834 33 0.019
cellular amine metabolic process GO:0044106 38 0.019
organelle localization GO:0051640 55 0.019
regulation of anatomical structure size GO:0090066 135 0.019
Mouse
sexual reproduction GO:0019953 148 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
cellular response to mechanical stimulus GO:0071260 48 0.019
vesicle mediated transport GO:0016192 181 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
negative regulation of developmental process GO:0051093 125 0.018
Mouse
regulation of peptide transport GO:0090087 87 0.018
regulation of peptide secretion GO:0002791 82 0.018
lipid metabolic process GO:0006629 283 0.018
biological adhesion GO:0022610 110 0.018
synaptic vesicle amine transport GO:0015842 3 0.018
single organismal cell cell adhesion GO:0016337 42 0.018
positive regulation of camp biosynthetic process GO:0030819 28 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
single organism cell adhesion GO:0098602 46 0.018
negative regulation of nervous system development GO:0051961 79 0.018
Mouse
positive regulation of cytokine production GO:0001819 42 0.018
actin filament based process GO:0030029 86 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
organic hydroxy compound transport GO:0015850 77 0.018
neuron development GO:0048666 286 0.018
Mouse
divalent inorganic cation transport GO:0072511 134 0.018
positive regulation of lipid biosynthetic process GO:0046889 25 0.018
response to decreased oxygen levels GO:0036293 237 0.018
parturition GO:0007567 10 0.018
striated muscle tissue development GO:0014706 58 0.018
regulation of jak stat cascade GO:0046425 21 0.018
negative regulation of smooth muscle contraction GO:0045986 7 0.017
regulation of cell development GO:0060284 263 0.017
Mouse
cardiovascular system development GO:0072358 134 0.017
vasculature development GO:0001944 70 0.017
synapse organization GO:0050808 46 0.017
catecholamine secretion GO:0050432 33 0.017
response to toxic substance GO:0009636 133 0.017
metal ion homeostasis GO:0055065 186 0.017
cellular response to alkaloid GO:0071312 25 0.017
development of primary female sexual characteristics GO:0046545 56 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
regulation of tube size GO:0035150 89 0.017
saliva secretion GO:0046541 3 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
cation homeostasis GO:0055080 195 0.017
gonadotropin secretion GO:0032274 8 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
regulation of neuron differentiation GO:0045664 208 0.017
Mouse
purine containing compound metabolic process GO:0072521 253 0.017
negative regulation of secretion by cell GO:1903531 72 0.017
positive regulation of protein transport GO:0051222 41 0.017
regulation of developmental growth GO:0048638 45 0.016
Mouse
peptide hormone secretion GO:0030072 84 0.016
catecholamine transport GO:0051937 37 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.016
membrane organization GO:0061024 94 0.016
synaptic transmission glutamatergic GO:0035249 33 0.016
regulation of cytokine production GO:0001817 56 0.016
circulatory system process GO:0003013 183 0.016
protein heterooligomerization GO:0051291 89 0.016
regulation of synaptic transmission GO:0050804 141 0.016
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.016
cellular component morphogenesis GO:0032989 155 0.016
Mouse
blood circulation GO:0008015 183 0.016
positive regulation of cell development GO:0010720 176 0.016
Mouse
excretion GO:0007588 24 0.016
female pregnancy GO:0007565 122 0.016
regulation of actin filament based movement GO:1903115 12 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
negative regulation of hormone secretion GO:0046888 46 0.016
amine metabolic process GO:0009308 38 0.016
amide transport GO:0042886 105 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
cellular response to hexose stimulus GO:0071331 65 0.016
proteolysis GO:0006508 175 0.015
regulation of feeding behavior GO:0060259 14 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
cation transport GO:0006812 382 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
regulation of metal ion transport GO:0010959 118 0.015
phospholipase c activating serotonin receptor signaling pathway GO:0007208 2 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
nucleoside metabolic process GO:0009116 179 0.015
cytoplasmic transport GO:0016482 115 0.015
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.015
cellular response to reactive oxygen species GO:0034614 55 0.015
negative regulation of neuron differentiation GO:0045665 62 0.015
magnesium ion homeostasis GO:0010960 2 0.015
regulation of follicle stimulating hormone secretion GO:0046880 5 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
lipid biosynthetic process GO:0008610 128 0.015
detection of temperature stimulus GO:0016048 4 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
negative regulation of cell communication GO:0010648 158 0.015
sequestering of calcium ion GO:0051208 8 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
Mouse
regulation of locomotion GO:0040012 148 0.014
Mouse
negative regulation of muscle contraction GO:0045932 8 0.014

Nkx6-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.026
central nervous system disease DOID:331 0 0.021
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
kidney disease DOID:557 0 0.020
urinary system disease DOID:18 0 0.020