Rattus norvegicus

17 known processes

Clk3

CDC-like kinase 3

Clk3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.124
Human Yeast
regulation of nucleic acid templated transcription GO:1903506 380 0.088
Yeast
organophosphate metabolic process GO:0019637 370 0.074
protein autophosphorylation GO:0046777 66 0.062
Yeast Mouse
regulation of rna biosynthetic process GO:2001141 381 0.057
Yeast
cellular catabolic process GO:0044248 295 0.057
nucleobase containing small molecule metabolic process GO:0055086 316 0.052
intracellular signal transduction GO:0035556 314 0.045
regulation of transcription dna templated GO:0006355 374 0.045
Yeast
nitrogen compound transport GO:0071705 229 0.044
macromolecule localization GO:0033036 252 0.041
purine ribonucleotide metabolic process GO:0009150 227 0.041
regulation of cellular component organization GO:0051128 368 0.040
purine ribonucleoside metabolic process GO:0046128 168 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
nucleotide metabolic process GO:0009117 279 0.039
transcription dna templated GO:0006351 377 0.038
Yeast
negative regulation of metabolic process GO:0009892 331 0.038
Yeast
intracellular transport GO:0046907 185 0.037
regulation of cell differentiation GO:0045595 320 0.036
nucleobase containing compound catabolic process GO:0034655 152 0.035
regulation of rna metabolic process GO:0051252 391 0.035
Human Yeast
organic cyclic compound catabolic process GO:1901361 175 0.035
protein phosphorylation GO:0006468 345 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.035
organic substance catabolic process GO:1901575 316 0.035
glycosyl compound metabolic process GO:1901657 182 0.034
nucleic acid templated transcription GO:0097659 379 0.034
Yeast
heterocycle catabolic process GO:0046700 167 0.034
regulation of molecular function GO:0065009 398 0.034
positive regulation of rna metabolic process GO:0051254 203 0.033
cation transport GO:0006812 382 0.033
catabolic process GO:0009056 351 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
Yeast
regulation of catalytic activity GO:0050790 304 0.032
purine nucleoside triphosphate metabolic process GO:0009144 141 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
homeostatic process GO:0042592 331 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
programmed cell death GO:0012501 392 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
oxidation reduction process GO:0055114 304 0.030
single organism catabolic process GO:0044712 283 0.029
organelle organization GO:0006996 266 0.029
peptidyl amino acid modification GO:0018193 126 0.029
Yeast Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
rna biosynthetic process GO:0032774 380 0.029
Yeast
purine nucleoside metabolic process GO:0042278 169 0.029
negative regulation of nucleic acid templated transcription GO:1903507 117 0.029
Yeast
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
purine containing compound metabolic process GO:0072521 253 0.028
regulation of signal transduction GO:0009966 318 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
ribonucleoside metabolic process GO:0009119 174 0.027
regulation of protein metabolic process GO:0051246 289 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
Yeast
purine containing compound catabolic process GO:0072523 138 0.026
cellular nitrogen compound catabolic process GO:0044270 163 0.026
response to inorganic substance GO:0010035 377 0.026
nucleoside triphosphate catabolic process GO:0009143 123 0.026
central nervous system development GO:0007417 311 0.025
single organism biosynthetic process GO:0044711 342 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
cellular component biogenesis GO:0044085 368 0.024
positive regulation of molecular function GO:0044093 230 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
organonitrogen compound biosynthetic process GO:1901566 167 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
proteolysis GO:0006508 175 0.024
cytoskeleton organization GO:0007010 111 0.024
cellular response to stress GO:0033554 269 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
regulation of nervous system development GO:0051960 264 0.024
head development GO:0060322 247 0.023
transmembrane transport GO:0055085 412 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
Yeast
purine ribonucleotide catabolic process GO:0009154 136 0.023
regulation of programmed cell death GO:0043067 341 0.023
nucleoside metabolic process GO:0009116 179 0.023
negative regulation of cell death GO:0060548 229 0.023
cellular homeostasis GO:0019725 252 0.023
amine metabolic process GO:0009308 38 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
Yeast
ribonucleotide catabolic process GO:0009261 136 0.022
secretion by cell GO:0032940 248 0.022
ribonucleoside monophosphate metabolic process GO:0009161 88 0.022
regulation of phosphorylation GO:0042325 248 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
organophosphate catabolic process GO:0046434 148 0.022
carboxylic acid metabolic process GO:0019752 289 0.021
cation transmembrane transport GO:0098655 263 0.021
ribonucleoside triphosphate metabolic process GO:0009199 141 0.021
aromatic compound catabolic process GO:0019439 168 0.021
secretion GO:0046903 307 0.021
organic acid metabolic process GO:0006082 292 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
metal ion transport GO:0030001 289 0.021
nucleotide catabolic process GO:0009166 139 0.020
response to peptide GO:1901652 292 0.020
nucleoside monophosphate metabolic process GO:0009123 93 0.020
macromolecular complex assembly GO:0065003 273 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
regulation of secretion GO:0051046 224 0.020
regulation of neuron differentiation GO:0045664 208 0.020
purine ribonucleoside catabolic process GO:0046130 124 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
chemical homeostasis GO:0048878 292 0.020
cell projection organization GO:0030030 302 0.020
regulation of apoptotic process GO:0042981 335 0.019
negative regulation of gene expression GO:0010629 199 0.019
Yeast
regulation of multicellular organismal development GO:2000026 376 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
glycosyl compound catabolic process GO:1901658 126 0.019
brain development GO:0007420 247 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
Yeast
cellular component assembly GO:0022607 360 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
cytoplasmic transport GO:0016482 115 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
response to metal ion GO:0010038 253 0.018
ribonucleoside catabolic process GO:0042454 126 0.018
positive regulation of transport GO:0051050 245 0.018
peptidyl tyrosine phosphorylation GO:0018108 72 0.018
Yeast Mouse
response to external biotic stimulus GO:0043207 221 0.018
ion transmembrane transport GO:0034220 365 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
negative regulation of signaling GO:0023057 157 0.018
positive regulation of signaling GO:0023056 270 0.018
cellular ketone metabolic process GO:0042180 51 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
apoptotic process GO:0006915 381 0.017
cellular lipid metabolic process GO:0044255 208 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
regulation of catabolic process GO:0009894 113 0.017
cellular amine metabolic process GO:0044106 38 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
lipid metabolic process GO:0006629 283 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of gene expression GO:0010628 244 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
cellular component movement GO:0006928 248 0.016
response to acid chemical GO:0001101 222 0.016
regulation of neuron projection development GO:0010975 161 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
Yeast
regulation of neurogenesis GO:0050767 247 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
Yeast
regulation of protein phosphorylation GO:0001932 183 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
macromolecular complex subunit organization GO:0043933 339 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
Yeast
negative regulation of molecular function GO:0044092 133 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
axis specification GO:0009798 4 0.015
aging GO:0007568 241 0.015
dna metabolic process GO:0006259 96 0.015
regulation of cellular localization GO:0060341 263 0.015
establishment of protein localization GO:0045184 141 0.015
ras protein signal transduction GO:0007265 29 0.015
cellular chemical homeostasis GO:0055082 247 0.015
tissue development GO:0009888 252 0.015
regulation of transferase activity GO:0051338 123 0.015
regulation of secretion by cell GO:1903530 208 0.015
atp metabolic process GO:0046034 72 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
rna localization GO:0006403 4 0.015
spindle organization GO:0007051 2 0.015
generation of precursor metabolites and energy GO:0006091 62 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
response to nutrient levels GO:0031667 370 0.015
cell motility GO:0048870 202 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
regulation of homeostatic process GO:0032844 101 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.014
actin filament based process GO:0030029 86 0.014
positive regulation of developmental process GO:0051094 283 0.014
heart morphogenesis GO:0003007 3 0.014
regulation of protein modification process GO:0031399 194 0.014
purine nucleoside monophosphate metabolic process GO:0009126 84 0.014
learning or memory GO:0007611 90 0.014
oxoacid metabolic process GO:0043436 290 0.014
single organism organelle organization GO:1902589 180 0.014
regulation of cell development GO:0060284 263 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
Yeast
atp catabolic process GO:0006200 54 0.014
neuron projection development GO:0031175 273 0.014
protein complex biogenesis GO:0070271 263 0.014
nuclear transport GO:0051169 49 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
cell migration GO:0016477 197 0.014
response to wounding GO:0009611 254 0.013
regulation of system process GO:0044057 208 0.013
ion homeostasis GO:0050801 212 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
positive regulation of secretion GO:0051047 140 0.013
multicellular organism growth GO:0035264 1 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
response to nutrient GO:0007584 248 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
response to cytokine GO:0034097 215 0.013
cell cycle checkpoint GO:0000075 2 0.013
glycerolipid metabolic process GO:0046486 67 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
behavior GO:0007610 205 0.013
response to oxygen levels GO:0070482 265 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
positive regulation of nervous system development GO:0051962 178 0.013
multicellular organism reproduction GO:0032504 233 0.013
cellular cation homeostasis GO:0030003 180 0.013
single organism cellular localization GO:1902580 102 0.013
purine nucleoside monophosphate catabolic process GO:0009128 55 0.013
regulation of cell projection organization GO:0031344 175 0.013
protein complex assembly GO:0006461 263 0.012
protein complex subunit organization GO:0071822 302 0.012
anion transport GO:0006820 178 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
respiratory system process GO:0003016 3 0.012
embryonic pattern specification GO:0009880 1 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
membrane organization GO:0061024 94 0.012
nucleoside catabolic process GO:0009164 126 0.012
nucleoside monophosphate catabolic process GO:0009125 56 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
neurological system process GO:0050877 219 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
mrna 3 end processing GO:0031124 1 0.012
response to decreased oxygen levels GO:0036293 237 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
divalent metal ion transport GO:0070838 132 0.012
cellular ion homeostasis GO:0006873 184 0.012
neuron death GO:0070997 127 0.012
anterior posterior pattern specification GO:0009952 1 0.012
response to ethanol GO:0045471 162 0.012
response to oxidative stress GO:0006979 186 0.011
sequestering of metal ion GO:0051238 9 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
response to toxic substance GO:0009636 133 0.011
response to extracellular stimulus GO:0009991 380 0.011
nucleic acid transport GO:0050657 3 0.011
calcium ion homeostasis GO:0055074 162 0.011
rna processing GO:0006396 22 0.011
Human
single organism intracellular transport GO:1902582 166 0.011
muscle system process GO:0003012 115 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
positive regulation of immune system process GO:0002684 90 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
response to hypoxia GO:0001666 231 0.011
cation homeostasis GO:0055080 195 0.011
sequestering of calcium ion GO:0051208 8 0.011
reproduction GO:0000003 245 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
response to biotic stimulus GO:0009607 226 0.011
hormone transport GO:0009914 121 0.011
glycogen metabolic process GO:0005977 23 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
signal release GO:0023061 145 0.010
carboxylic acid transport GO:0046942 115 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
synaptic transmission GO:0007268 235 0.010
response to peptide hormone GO:0043434 278 0.010
adult locomotory behavior GO:0008344 4 0.010
cognition GO:0050890 92 0.010
neuron development GO:0048666 286 0.010
calcium ion transport GO:0006816 131 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
chromosome segregation GO:0007059 2 0.010
locomotion GO:0040011 237 0.010

Clk3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.044
inherited metabolic disorder DOID:655 0 0.044
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
myopathy DOID:423 0 0.015
muscular disease DOID:0080000 0 0.015
musculoskeletal system disease DOID:17 0 0.015
muscle tissue disease DOID:66 0 0.015
central nervous system disease DOID:331 0 0.011