Rattus norvegicus

98 known processes

Herpud1

homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

(Aliases: Sup)

Herpud1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 252 0.275
transcription dna templated GO:0006351 377 0.157
rna metabolic process GO:0016070 406 0.155
nucleic acid templated transcription GO:0097659 379 0.136
regulation of transcription dna templated GO:0006355 374 0.124
regulation of nucleic acid templated transcription GO:1903506 380 0.117
rna biosynthetic process GO:0032774 380 0.111
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.109
regulation of rna metabolic process GO:0051252 391 0.101
negative regulation of gene expression GO:0010629 199 0.090
negative regulation of macromolecule metabolic process GO:0010605 260 0.079
regulation of cell differentiation GO:0045595 320 0.078
regulation of multicellular organismal development GO:2000026 376 0.077
regulation of rna biosynthetic process GO:2001141 381 0.075
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.072
negative regulation of biosynthetic process GO:0009890 168 0.072
catabolic process GO:0009056 351 0.071
cation transport GO:0006812 382 0.070
homeostatic process GO:0042592 331 0.064
negative regulation of metabolic process GO:0009892 331 0.064
carboxylic acid metabolic process GO:0019752 289 0.064
intracellular signal transduction GO:0035556 314 0.063
negative regulation of developmental process GO:0051093 125 0.063
organic substance catabolic process GO:1901575 316 0.061
regulation of signal transduction GO:0009966 318 0.060
negative regulation of nucleic acid templated transcription GO:1903507 117 0.058
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.056
cellular amino acid metabolic process GO:0006520 107 0.055
negative regulation of response to stimulus GO:0048585 155 0.054
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.054
regulation of molecular function GO:0065009 398 0.054
organic acid metabolic process GO:0006082 292 0.054
response to nutrient levels GO:0031667 370 0.053
regulation of proteasomal protein catabolic process GO:0061136 4 0.051
negative regulation of cellular biosynthetic process GO:0031327 161 0.051
positive regulation of biosynthetic process GO:0009891 319 0.051
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.051
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.050
negative regulation of multicellular organismal process GO:0051241 203 0.049
tissue development GO:0009888 252 0.049
response to extracellular stimulus GO:0009991 380 0.048
programmed cell death GO:0012501 392 0.046
ubiquitin dependent protein catabolic process GO:0006511 14 0.045
regulation of apoptotic process GO:0042981 335 0.045
regulation of programmed cell death GO:0043067 341 0.045
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.044
oxoacid metabolic process GO:0043436 290 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
negative regulation of cellular metabolic process GO:0031324 281 0.043
negative regulation of rna biosynthetic process GO:1902679 118 0.043
response to nutrient GO:0007584 248 0.043
apoptotic process GO:0006915 381 0.042
cellular response to endogenous stimulus GO:0071495 377 0.042
transmembrane transport GO:0055085 412 0.042
neuron differentiation GO:0030182 368 0.041
amine metabolic process GO:0009308 38 0.040
positive regulation of multicellular organismal process GO:0051240 387 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
negative regulation of rna metabolic process GO:0051253 123 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.038
cellular amine metabolic process GO:0044106 38 0.037
cellular catabolic process GO:0044248 295 0.036
positive regulation of cellular biosynthetic process GO:0031328 295 0.036
regulation of intracellular signal transduction GO:1902531 218 0.035
regulation of protein metabolic process GO:0051246 289 0.035
regulation of homeostatic process GO:0032844 101 0.035
negative regulation of signaling GO:0023057 157 0.034
cellular lipid metabolic process GO:0044255 208 0.034
single organism catabolic process GO:0044712 283 0.034
organophosphate metabolic process GO:0019637 370 0.033
cellular response to stress GO:0033554 269 0.032
regulation of cellular component organization GO:0051128 368 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.031
cellular ketone metabolic process GO:0042180 51 0.031
negative regulation of cell death GO:0060548 229 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
positive regulation of rna metabolic process GO:0051254 203 0.030
intracellular transport GO:0046907 185 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
regulation of cell development GO:0060284 263 0.028
response to biotic stimulus GO:0009607 226 0.028
axis specification GO:0009798 4 0.028
response to inorganic substance GO:0010035 377 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
response to hypoxia GO:0001666 231 0.028
cation transmembrane transport GO:0098655 263 0.028
protein phosphorylation GO:0006468 345 0.027
single organism biosynthetic process GO:0044711 342 0.027
response to decreased oxygen levels GO:0036293 237 0.027
ion homeostasis GO:0050801 212 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
cellular response to nitrogen compound GO:1901699 210 0.026
negative regulation of transcription dna templated GO:0045892 116 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.025
negative regulation of molecular function GO:0044092 133 0.025
positive regulation of cell death GO:0010942 184 0.025
positive regulation of gene expression GO:0010628 244 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
cation homeostasis GO:0055080 195 0.024
response to oxygen levels GO:0070482 265 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
muscle tissue development GO:0060537 58 0.024
regulation of fat cell differentiation GO:0045598 3 0.024
proteolysis GO:0006508 175 0.024
regulation of immune system process GO:0002682 123 0.024
ion transmembrane transport GO:0034220 365 0.024
peptidyl amino acid modification GO:0018193 126 0.023
anterior posterior pattern specification GO:0009952 1 0.023
negative regulation of innate immune response GO:0045824 4 0.023
chemical homeostasis GO:0048878 292 0.023
regulation of muscle tissue development GO:1901861 25 0.022
organic anion transport GO:0015711 132 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
negative regulation of cell communication GO:0010648 158 0.022
regulation of catalytic activity GO:0050790 304 0.022
negative regulation of phosphorus metabolic process GO:0010563 80 0.022
cell projection organization GO:0030030 302 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.021
positive regulation of developmental process GO:0051094 283 0.021
purine containing compound metabolic process GO:0072521 253 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
response to peptide GO:1901652 292 0.021
multicellular organism reproduction GO:0032504 233 0.021
aging GO:0007568 241 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
negative regulation of signal transduction GO:0009968 83 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
metal ion homeostasis GO:0055065 186 0.020
anion transport GO:0006820 178 0.020
regulation of ion transport GO:0043269 245 0.020
regulation of canonical wnt signaling pathway GO:0060828 4 0.020
regulation of nervous system development GO:0051960 264 0.020
lipid metabolic process GO:0006629 283 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
protein complex subunit organization GO:0071822 302 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
modification dependent macromolecule catabolic process GO:0043632 14 0.019
cellular component assembly GO:0022607 360 0.019
metal ion transport GO:0030001 289 0.019
cellular component biogenesis GO:0044085 368 0.019
neuron projection development GO:0031175 273 0.019
protein complex biogenesis GO:0070271 263 0.019
multi organism reproductive process GO:0044703 262 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
regulation of response to stress GO:0080134 126 0.019
central nervous system development GO:0007417 311 0.018
secretion GO:0046903 307 0.018
cellular response to peptide GO:1901653 133 0.018
regulation of neuron differentiation GO:0045664 208 0.018
regulation of system process GO:0044057 208 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.018
protein complex assembly GO:0006461 263 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
neuron death GO:0070997 127 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
signal transduction by phosphorylation GO:0023014 144 0.017
positive regulation of molecular function GO:0044093 230 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
response to oxidative stress GO:0006979 186 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
neuron development GO:0048666 286 0.017
membrane organization GO:0061024 94 0.017
regulation of cell proliferation GO:0042127 359 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
apoptotic signaling pathway GO:0097190 27 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
regulation of cytokine production GO:0001817 56 0.016
secretion by cell GO:0032940 248 0.016
cellular response to unfolded protein GO:0034620 2 0.016
protein catabolic process GO:0030163 30 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
protein oligomerization GO:0051259 191 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
cellular cation homeostasis GO:0030003 180 0.016
cellular homeostasis GO:0019725 252 0.016
single organism organelle organization GO:1902589 180 0.016
regulation of protein modification process GO:0031399 194 0.015
regulation of neuron projection development GO:0010975 161 0.015
posttranscriptional regulation of gene expression GO:0010608 37 0.015
macromolecule catabolic process GO:0009057 58 0.015
amino acid transport GO:0006865 70 0.015
regulation of neurogenesis GO:0050767 247 0.015
cellular response to topologically incorrect protein GO:0035967 3 0.015
response to external biotic stimulus GO:0043207 221 0.015
organelle organization GO:0006996 266 0.015
reproduction GO:0000003 245 0.015
response to peptide hormone GO:0043434 278 0.015
striated muscle tissue development GO:0014706 58 0.015
muscle structure development GO:0061061 87 0.015
positive regulation of cell communication GO:0010647 271 0.015
response to acid chemical GO:0001101 222 0.015
modification dependent protein catabolic process GO:0019941 14 0.015
brain development GO:0007420 247 0.015
regulation of catabolic process GO:0009894 113 0.015
cytoplasmic transport GO:0016482 115 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
cell type specific apoptotic process GO:0097285 134 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
oxidation reduction process GO:0055114 304 0.014
organic acid transport GO:0015849 116 0.014
nucleoside metabolic process GO:0009116 179 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
single organism reproductive process GO:0044702 297 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
mapk cascade GO:0000165 140 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
skeletal muscle tissue development GO:0007519 31 0.014
maintenance of location GO:0051235 17 0.014
lipid modification GO:0030258 52 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
sequestering of calcium ion GO:0051208 8 0.014
negative regulation of homeostatic process GO:0032845 47 0.014
cardiovascular system development GO:0072358 134 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
mrna transcription from rna polymerase ii promoter GO:0042789 1 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
regulation of cell projection organization GO:0031344 175 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
cellular macromolecule catabolic process GO:0044265 29 0.014
regulation of phosphorylation GO:0042325 248 0.014
head development GO:0060322 247 0.014
calcium ion transport GO:0006816 131 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
cell cell signaling GO:0007267 335 0.013
response to wounding GO:0009611 254 0.013
positive regulation of signaling GO:0023056 270 0.013
regulation of membrane potential GO:0042391 110 0.013
immune system process GO:0002376 204 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
response to growth factor GO:0070848 189 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
dna metabolic process GO:0006259 96 0.013
regulation of muscle organ development GO:0048634 26 0.013
neurological system process GO:0050877 219 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
amide transport GO:0042886 105 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
circulatory system process GO:0003013 183 0.013
nitrogen compound transport GO:0071705 229 0.013
cytokine production GO:0001816 61 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
carboxylic acid transport GO:0046942 115 0.013
regulation of neuron death GO:1901214 115 0.013
endoplasmic reticulum unfolded protein response GO:0030968 2 0.012
sequestering of metal ion GO:0051238 9 0.012
small molecule biosynthetic process GO:0044283 124 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
circulatory system development GO:0072359 134 0.012
vesicle mediated transport GO:0016192 181 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
positive regulation of cell development GO:0010720 176 0.012
positive regulation of nervous system development GO:0051962 178 0.012
macromolecular complex assembly GO:0065003 273 0.012
regulation of p38mapk cascade GO:1900744 1 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
reproductive process GO:0022414 372 0.012
response to ethanol GO:0045471 162 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
embryonic pattern specification GO:0009880 1 0.012
growth GO:0040007 165 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
cellular protein catabolic process GO:0044257 19 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
cell part morphogenesis GO:0032990 123 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
heart morphogenesis GO:0003007 3 0.012
multicellular organism growth GO:0035264 1 0.012
regulation of growth GO:0040008 105 0.012
blood circulation GO:0008015 183 0.012
muscle organ development GO:0007517 50 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
regulation of cell growth GO:0001558 85 0.012
nucleotide metabolic process GO:0009117 279 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
gland development GO:0048732 155 0.011
positive regulation of cytokine production GO:0001819 42 0.011
response to toxic substance GO:0009636 133 0.011
lymphocyte homeostasis GO:0002260 2 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
response to reactive oxygen species GO:0000302 120 0.011
organic acid catabolic process GO:0016054 49 0.011
response to bacterium GO:0009617 200 0.011
endocytosis GO:0006897 84 0.011
response to estradiol GO:0032355 164 0.011
single organism intracellular transport GO:1902582 166 0.011
lipid storage GO:0019915 1 0.011
regulation of hormone levels GO:0010817 187 0.011
circadian rhythm GO:0007623 88 0.011
anion transmembrane transport GO:0098656 77 0.011
behavior GO:0007610 205 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
single organism membrane organization GO:0044802 74 0.011
response to cytokine GO:0034097 215 0.011
response to glucose GO:0009749 136 0.011
positive regulation of signal transduction GO:0009967 175 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.010
protein autophosphorylation GO:0046777 66 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
heterocycle catabolic process GO:0046700 167 0.010
gastrulation GO:0007369 2 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
regulation of body fluid levels GO:0050878 90 0.010
endochondral bone growth GO:0003416 3 0.010
regulation of mapk cascade GO:0043408 116 0.010
entrainment of circadian clock GO:0009649 3 0.010
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.010
cell morphogenesis GO:0000902 142 0.010
ras protein signal transduction GO:0007265 29 0.010
protein localization GO:0008104 191 0.010
cellular chemical homeostasis GO:0055082 247 0.010
cell cycle checkpoint GO:0000075 2 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
muscle system process GO:0003012 115 0.010

Herpud1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.015
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
inherited metabolic disorder DOID:655 0 0.013
nervous system disease DOID:863 0 0.013