Rattus norvegicus

163 known processes

Nppb

natriuretic peptide precursor B

(Aliases: BNP,Bnf)

Nppb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 226 0.320
cation transmembrane transport GO:0098655 263 0.300
regulation of multicellular organismal development GO:2000026 376 0.237
response to extracellular stimulus GO:0009991 380 0.236
response to corticosteroid GO:0031960 235 0.235
single organism biosynthetic process GO:0044711 342 0.229
circulatory system process GO:0003013 183 0.221
regulation of system process GO:0044057 208 0.206
homeostatic process GO:0042592 331 0.167
response to bacterium GO:0009617 200 0.165
positive regulation of multicellular organismal process GO:0051240 387 0.149
response to nutrient GO:0007584 248 0.137
organophosphate metabolic process GO:0019637 370 0.122
cation homeostasis GO:0055080 195 0.116
response to decreased oxygen levels GO:0036293 237 0.110
response to hypoxia GO:0001666 231 0.106
response to external biotic stimulus GO:0043207 221 0.099
response to other organism GO:0051707 220 0.098
response to estradiol GO:0032355 164 0.096
secretion GO:0046903 307 0.094
cellular response to endogenous stimulus GO:0071495 377 0.084
response to organophosphorus GO:0046683 102 0.083
response to estrogen GO:0043627 232 0.082
cellular response to external stimulus GO:0071496 118 0.081
ion transmembrane transport GO:0034220 365 0.080
positive regulation of signaling GO:0023056 270 0.078
cellular component assembly GO:0022607 360 0.078
carboxylic acid biosynthetic process GO:0046394 83 0.078
response to camp GO:0051591 91 0.075
regulation of nervous system development GO:0051960 264 0.073
metal ion transport GO:0030001 289 0.072
defense response GO:0006952 194 0.072
regulation of intracellular signal transduction GO:1902531 218 0.071
response to insulin GO:0032868 133 0.068
Rat
response to purine containing compound GO:0014074 126 0.066
positive regulation of biosynthetic process GO:0009891 319 0.065
positive regulation of phosphate metabolic process GO:0045937 262 0.065
response to nutrient levels GO:0031667 370 0.062
neuron differentiation GO:0030182 368 0.062
cgmp biosynthetic process GO:0006182 15 0.062
regulation of cell growth GO:0001558 85 0.061
cation transport GO:0006812 382 0.060
cellular response to oxygen containing compound GO:1901701 386 0.059
single organism reproductive process GO:0044702 297 0.059
divalent inorganic cation homeostasis GO:0072507 165 0.058
positive regulation of neurogenesis GO:0050769 165 0.057
cellular chemical homeostasis GO:0055082 247 0.056
positive regulation of developmental process GO:0051094 283 0.055
cellular homeostasis GO:0019725 252 0.055
inorganic cation transmembrane transport GO:0098662 202 0.054
leukocyte differentiation GO:0002521 30 0.051
cardiac muscle contraction GO:0060048 27 0.050
response to heat GO:0009408 60 0.049
positive regulation of transport GO:0051050 245 0.049
regulation of catalytic activity GO:0050790 304 0.048
cell growth GO:0016049 104 0.048
blood circulation GO:0008015 183 0.047
regulation of protein metabolic process GO:0051246 289 0.047
tissue development GO:0009888 252 0.046
multicellular organism reproduction GO:0032504 233 0.045
positive regulation of phosphorus metabolic process GO:0010562 262 0.045
behavior GO:0007610 205 0.044
response to monosaccharide GO:0034284 159 0.044
positive regulation of programmed cell death GO:0043068 157 0.044
small molecule biosynthetic process GO:0044283 124 0.043
organophosphate biosynthetic process GO:0090407 143 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
cell activation GO:0001775 97 0.043
response to vitamin GO:0033273 131 0.043
cellular response to hormone stimulus GO:0032870 247 0.042
multi organism reproductive process GO:0044703 262 0.042
response to glucocorticoid GO:0051384 223 0.040
response to oxygen levels GO:0070482 265 0.040
female pregnancy GO:0007565 122 0.040
response to peptide GO:1901652 292 0.040
response to hexose GO:0009746 144 0.040
lipid biosynthetic process GO:0008610 128 0.039
nucleic acid templated transcription GO:0097659 379 0.039
cellular response to insulin stimulus GO:0032869 81 0.039
ion homeostasis GO:0050801 212 0.039
cellular component movement GO:0006928 248 0.038
divalent metal ion transport GO:0070838 132 0.038
response to vitamin a GO:0033189 36 0.038
cellular ion homeostasis GO:0006873 184 0.037
positive regulation of response to stimulus GO:0048584 285 0.037
response to hyperoxia GO:0055093 45 0.037
regulation of cell differentiation GO:0045595 320 0.037
multicellular organismal reproductive process GO:0048609 233 0.036
reproduction GO:0000003 245 0.036
rna metabolic process GO:0016070 406 0.036
transmission of nerve impulse GO:0019226 42 0.036
positive regulation of intracellular signal transduction GO:1902533 138 0.035
multicellular organismal signaling GO:0035637 44 0.035
positive regulation of cell development GO:0010720 176 0.035
regulation of transmembrane transport GO:0034762 122 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.034
cellular cation homeostasis GO:0030003 180 0.034
regulation of ion transport GO:0043269 245 0.033
cellular calcium ion homeostasis GO:0006874 160 0.032
detection of stimulus GO:0051606 24 0.032
regulation of cell development GO:0060284 263 0.032
neurological system process GO:0050877 219 0.032
response to toxic substance GO:0009636 133 0.032
monovalent inorganic cation transport GO:0015672 172 0.032
anatomical structure formation involved in morphogenesis GO:0048646 83 0.031
regulation of secretion GO:0051046 224 0.031
chemical homeostasis GO:0048878 292 0.031
protein phosphorylation GO:0006468 345 0.031
regulation of molecular function GO:0065009 398 0.030
regulation of ion transmembrane transport GO:0034765 121 0.030
response to cytokine GO:0034097 215 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
negative regulation of metabolic process GO:0009892 331 0.030
regeneration GO:0031099 163 0.030
transformation of host cell by virus GO:0019087 4 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
response to oxidative stress GO:0006979 186 0.028
macromolecule localization GO:0033036 252 0.028
positive regulation of apoptotic process GO:0043065 154 0.028
regulation of growth GO:0040008 105 0.028
response to ketone GO:1901654 182 0.028
regulation of ion transmembrane transporter activity GO:0032412 48 0.028
phospholipid metabolic process GO:0006644 61 0.028
lipid metabolic process GO:0006629 283 0.028
positive regulation of signal transduction GO:0009967 175 0.028
reproductive process GO:0022414 372 0.027
negative regulation of biosynthetic process GO:0009890 168 0.027
oxidation reduction process GO:0055114 304 0.027
organ regeneration GO:0031100 101 0.027
blood vessel morphogenesis GO:0048514 58 0.027
regulation of cell proliferation GO:0042127 359 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
neuron projection development GO:0031175 273 0.026
vasculature development GO:0001944 70 0.026
intracellular signal transduction GO:0035556 314 0.026
secretion by cell GO:0032940 248 0.026
metal ion homeostasis GO:0055065 186 0.025
regulation of cell projection organization GO:0031344 175 0.025
negative regulation of transcription dna templated GO:0045892 116 0.025
catabolic process GO:0009056 351 0.025
cellular component biogenesis GO:0044085 368 0.025
organic hydroxy compound metabolic process GO:1901615 115 0.025
positive regulation of molecular function GO:0044093 230 0.025
steroid biosynthetic process GO:0006694 48 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
cellular metal ion homeostasis GO:0006875 172 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
dephosphorylation GO:0016311 98 0.024
response to transition metal nanoparticle GO:1990267 122 0.024
macromolecular complex assembly GO:0065003 273 0.024
regulation of metal ion transport GO:0010959 118 0.024
protein homooligomerization GO:0051260 91 0.024
cellular divalent inorganic cation homeostasis GO:0072503 162 0.024
monoamine transport GO:0015844 43 0.023
striated muscle contraction GO:0006941 44 0.023
cellular response to molecule of bacterial origin GO:0071219 56 0.023
aging GO:0007568 241 0.023
cellular response to stress GO:0033554 269 0.023
transmembrane transport GO:0055085 412 0.022
coronary vasculature morphogenesis GO:0060977 3 0.022
myeloid leukocyte differentiation GO:0002573 20 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
protein secretion GO:0009306 34 0.022
immune system process GO:0002376 204 0.022
regulation of neurogenesis GO:0050767 247 0.021
response to lipopolysaccharide GO:0032496 191 0.021
reproductive system development GO:0061458 128 0.021
regulation of programmed cell death GO:0043067 341 0.021
apoptotic process GO:0006915 381 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
positive regulation of secretion by cell GO:1903532 128 0.021
developmental process involved in reproduction GO:0003006 159 0.021
protein complex assembly GO:0006461 263 0.021
regulation of blood pressure GO:0008217 83 0.021
regulation of blood vessel size GO:0050880 89 0.021
regulation of phagocytosis engulfment GO:0060099 4 0.021
regulation of anatomical structure size GO:0090066 135 0.020
cellular catabolic process GO:0044248 295 0.020
growth GO:0040007 165 0.020
cellular response to abiotic stimulus GO:0071214 85 0.020
cellular ketone metabolic process GO:0042180 51 0.020
regulation of phosphate metabolic process GO:0019220 349 0.020
response to increased oxygen levels GO:0036296 45 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
negative regulation of ion transport GO:0043271 51 0.020
regulation of membrane potential GO:0042391 110 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
muscle system process GO:0003012 115 0.019
response to acid chemical GO:0001101 222 0.019
regulation of hormone levels GO:0010817 187 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.019
nucleotide metabolic process GO:0009117 279 0.019
response to carbohydrate GO:0009743 183 0.019
coenzyme metabolic process GO:0006732 86 0.019
regulation of secretion by cell GO:1903530 208 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
muscle contraction GO:0006936 88 0.018
cellular response to lipid GO:0071396 201 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
regulation of signal transduction GO:0009966 318 0.018
response to activity GO:0014823 73 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
gamete generation GO:0007276 124 0.018
organ morphogenesis GO:0009887 75 0.018
cell projection organization GO:0030030 302 0.018
hematopoietic or lymphoid organ development GO:0048534 36 0.018
leukocyte migration GO:0050900 38 0.018
glycerolipid metabolic process GO:0046486 67 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
female gonad development GO:0008585 53 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
sodium ion transport GO:0006814 82 0.018
response to peptide hormone GO:0043434 278 0.018
rhythmic process GO:0048511 156 0.018
response to light stimulus GO:0009416 52 0.018
mapk cascade GO:0000165 140 0.018
response to wounding GO:0009611 254 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
divalent inorganic cation transport GO:0072511 134 0.017
regulation of apoptotic process GO:0042981 335 0.017
positive regulation of protein modification process GO:0031401 142 0.017
regulation of lipid biosynthetic process GO:0046890 38 0.017
gland development GO:0048732 155 0.017
proteolysis GO:0006508 175 0.017
myeloid cell differentiation GO:0030099 22 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
glycerophospholipid metabolic process GO:0006650 47 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
positive regulation of kinase activity GO:0033674 77 0.017
muscle cell differentiation GO:0042692 52 0.017
regulation of transcription dna templated GO:0006355 374 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
positive regulation of cell death GO:0010942 184 0.017
protein complex subunit organization GO:0071822 302 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
cellular response to fluid shear stress GO:0071498 4 0.017
regulation of transporter activity GO:0032409 50 0.017
sexual reproduction GO:0019953 148 0.016
response to antibiotic GO:0046677 39 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
positive regulation of hydrolase activity GO:0051345 86 0.016
cofactor metabolic process GO:0051186 95 0.016
regulation of cellular component organization GO:0051128 368 0.016
positive regulation of secretion GO:0051047 140 0.016
reproductive structure development GO:0048608 128 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
organic substance catabolic process GO:1901575 316 0.016
synaptic transmission GO:0007268 235 0.016
regulation of blood circulation GO:1903522 110 0.016
smooth muscle cell proliferation GO:0048659 77 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
positive regulation of gene expression GO:0010628 244 0.016
cardiac muscle cell contraction GO:0086003 10 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
regulation of extracellular matrix constituent secretion GO:0003330 2 0.015
positive regulation of nervous system development GO:0051962 178 0.015
regulation of cardiac muscle contraction GO:0055117 17 0.015
vesicle mediated transport GO:0016192 181 0.015
angiogenesis GO:0001525 53 0.015
regulation of organ formation GO:0003156 2 0.015
regulation of cellular component movement GO:0051270 150 0.015
positive regulation of phagocytosis engulfment GO:0060100 4 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
rna biosynthetic process GO:0032774 380 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
neuronal action potential GO:0019228 35 0.014
heart development GO:0007507 72 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
biological adhesion GO:0022610 110 0.014
alcohol metabolic process GO:0006066 77 0.014
programmed cell death GO:0012501 392 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
locomotion GO:0040011 237 0.014
carbohydrate homeostasis GO:0033500 75 0.014
steroid metabolic process GO:0008202 73 0.014
regulation of phosphorylation GO:0042325 248 0.014
cellular amine metabolic process GO:0044106 38 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
regulation of cytokine production GO:0001817 56 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
multi multicellular organism process GO:0044706 138 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
vasoconstriction GO:0042310 54 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
regulation of potassium ion transport GO:0043266 29 0.013
t cell activation GO:0042110 29 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
cellular response to lipopolysaccharide GO:0071222 55 0.013
regulation of transferase activity GO:0051338 123 0.013
male gamete generation GO:0048232 99 0.013
carboxylic acid transport GO:0046942 115 0.013
neuromuscular process GO:0050905 2 0.013
organ induction GO:0001759 1 0.013
regulation of neuron differentiation GO:0045664 208 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
regulation of hydrolase activity GO:0051336 143 0.013
female sex differentiation GO:0046660 59 0.013
response to dexamethasone GO:0071548 49 0.013
negative regulation of molecular function GO:0044092 133 0.013
cellular response to gonadotropin stimulus GO:0071371 17 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
rho protein signal transduction GO:0007266 11 0.012
ras protein signal transduction GO:0007265 29 0.012
axis specification GO:0009798 4 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
monocarboxylic acid transport GO:0015718 52 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
protein oligomerization GO:0051259 191 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
wound healing GO:0042060 122 0.012
regulation of synaptic transmission GO:0050804 141 0.012
hemopoiesis GO:0030097 34 0.012
purine containing compound metabolic process GO:0072521 253 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
vascular process in circulatory system GO:0003018 96 0.012
regulation of cellular localization GO:0060341 263 0.012
insecticide metabolic process GO:0017143 4 0.012
amine metabolic process GO:0009308 38 0.012
regulation of mapk cascade GO:0043408 116 0.012
neuron death GO:0070997 127 0.012
epithelial cell proliferation GO:0050673 54 0.012
negative regulation of transport GO:0051051 136 0.012
transcription dna templated GO:0006351 377 0.012
cellular response to biotic stimulus GO:0071216 59 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.011
response to interleukin 1 GO:0070555 55 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
tube development GO:0035295 89 0.011
regulation of immune system process GO:0002682 123 0.011
response to growth factor GO:0070848 189 0.011
regulation of protein secretion GO:0050708 28 0.011
positive regulation of necrotic cell death GO:0010940 4 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
response to gonadotropin GO:0034698 34 0.011
immune response GO:0006955 104 0.011
single organism cell adhesion GO:0098602 46 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
Rat
purine containing compound biosynthetic process GO:0072522 85 0.011
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.011
organ formation GO:0048645 3 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
circulatory system development GO:0072359 134 0.011
potassium ion transport GO:0006813 97 0.011
sensory perception of bitter taste GO:0050913 4 0.011
cellular response to alcohol GO:0097306 87 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
calcium ion transport GO:0006816 131 0.011
head development GO:0060322 247 0.011
protein complex biogenesis GO:0070271 263 0.011
positive regulation of immune system process GO:0002684 90 0.011
regulation of striated muscle contraction GO:0006942 21 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
neuron development GO:0048666 286 0.011
sex differentiation GO:0007548 113 0.011
neurotransmitter gated ion channel clustering GO:0072578 3 0.011
organic hydroxy compound transport GO:0015850 77 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.010
development of primary female sexual characteristics GO:0046545 56 0.010
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.010
cytokine production GO:0001816 61 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
response to reactive oxygen species GO:0000302 120 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
regulation of body fluid levels GO:0050878 90 0.010
organic hydroxy compound biosynthetic process GO:1901617 51 0.010
negative regulation of multicellular organismal metabolic process GO:0044252 4 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
regulation of response to external stimulus GO:0032101 106 0.010
extracellular matrix constituent secretion GO:0070278 4 0.010
development of primary sexual characteristics GO:0045137 107 0.010
negative regulation of ion transmembrane transporter activity GO:0032413 12 0.010

Nppb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.019
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
nervous system disease DOID:863 0 0.016
eye disease DOID:5614 0 0.015
respiratory system disease DOID:1579 0 0.010
lower respiratory tract disease DOID:0050161 0 0.010
disease of metabolism DOID:0014667 0 0.010
muscular disease DOID:0080000 0 0.010