Rattus norvegicus

0 known processes

Hs2st1

heparan sulfate 2-O-sulfotransferase 1

Hs2st1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular component movement GO:0006928 248 0.066
locomotion GO:0040011 237 0.062
neuron differentiation GO:0030182 368 0.060
cellular response to endogenous stimulus GO:0071495 377 0.059
carboxylic acid metabolic process GO:0019752 289 0.058
regulation of protein metabolic process GO:0051246 289 0.056
negative regulation of metabolic process GO:0009892 331 0.055
protein complex subunit organization GO:0071822 302 0.054
regulation of nucleic acid templated transcription GO:1903506 380 0.054
transcription dna templated GO:0006351 377 0.053
organic acid metabolic process GO:0006082 292 0.051
intracellular signal transduction GO:0035556 314 0.050
protein phosphorylation GO:0006468 345 0.050
regulation of phosphorus metabolic process GO:0051174 349 0.049
programmed cell death GO:0012501 392 0.048
positive regulation of response to stimulus GO:0048584 285 0.046
response to extracellular stimulus GO:0009991 380 0.045
regulation of phosphate metabolic process GO:0019220 349 0.044
nucleobase containing small molecule metabolic process GO:0055086 316 0.043
regulation of multicellular organismal development GO:2000026 376 0.043
protein complex biogenesis GO:0070271 263 0.043
cellular component assembly GO:0022607 360 0.042
regulation of cellular component organization GO:0051128 368 0.042
positive regulation of phosphate metabolic process GO:0045937 262 0.042
macromolecular complex subunit organization GO:0043933 339 0.041
neuron projection development GO:0031175 273 0.040
regulation of cellular amine metabolic process GO:0033238 8 0.040
regulation of cellular amino acid metabolic process GO:0006521 2 0.039
positive regulation of cellular protein metabolic process GO:0032270 167 0.039
regulation of phosphorylation GO:0042325 248 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.038
amine metabolic process GO:0009308 38 0.038
neuron development GO:0048666 286 0.038
cellular component biogenesis GO:0044085 368 0.038
cellular amine metabolic process GO:0044106 38 0.037
cell projection organization GO:0030030 302 0.037
negative regulation of signaling GO:0023057 157 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
response to nutrient levels GO:0031667 370 0.036
response to estrogen GO:0043627 232 0.036
regulation of cell migration GO:0030334 128 0.035
rna biosynthetic process GO:0032774 380 0.035
regulation of rna biosynthetic process GO:2001141 381 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.035
positive regulation of cell communication GO:0010647 271 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
regulation of signal transduction GO:0009966 318 0.035
regulation of catalytic activity GO:0050790 304 0.034
organelle organization GO:0006996 266 0.034
rna metabolic process GO:0016070 406 0.034
apoptotic process GO:0006915 381 0.034
lipid metabolic process GO:0006629 283 0.034
positive regulation of signaling GO:0023056 270 0.033
positive regulation of molecular function GO:0044093 230 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.033
macromolecular complex assembly GO:0065003 273 0.033
positive regulation of developmental process GO:0051094 283 0.033
negative regulation of cellular biosynthetic process GO:0031327 161 0.033
protein complex assembly GO:0006461 263 0.032
cellular ketone metabolic process GO:0042180 51 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
cell morphogenesis GO:0000902 142 0.032
anatomical structure morphogenesis GO:0009653 298 0.032
regulation of nervous system development GO:0051960 264 0.032
regulation of rna metabolic process GO:0051252 391 0.031
regulation of cell development GO:0060284 263 0.031
cell migration GO:0016477 197 0.031
behavior GO:0007610 205 0.030
cation transport GO:0006812 382 0.030
oxoacid metabolic process GO:0043436 290 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.030
catabolic process GO:0009056 351 0.030
synaptic growth at neuromuscular junction GO:0051124 1 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.030
regulation of neuron differentiation GO:0045664 208 0.029
organophosphate metabolic process GO:0019637 370 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
central nervous system development GO:0007417 311 0.029
regulation of protein modification process GO:0031399 194 0.029
regulation of molecular function GO:0065009 398 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.028
small gtpase mediated signal transduction GO:0007264 36 0.028
localization of cell GO:0051674 202 0.028
negative regulation of biosynthetic process GO:0009890 168 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
positive regulation of signal transduction GO:0009967 175 0.028
cellular response to cytokine stimulus GO:0071345 127 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
positive regulation of intracellular signal transduction GO:1902533 138 0.027
cell motility GO:0048870 202 0.027
cellular response to organonitrogen compound GO:0071417 197 0.026
response to growth factor GO:0070848 189 0.026
ion homeostasis GO:0050801 212 0.026
regulation of apoptotic process GO:0042981 335 0.026
dephosphorylation GO:0016311 98 0.026
tissue development GO:0009888 252 0.026
cell morphogenesis involved in differentiation GO:0000904 119 0.026
homeostatic process GO:0042592 331 0.026
inorganic cation transmembrane transport GO:0098662 202 0.025
regulation of cell differentiation GO:0045595 320 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
single organism catabolic process GO:0044712 283 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
regulation of protein phosphorylation GO:0001932 183 0.025
regulation of transcription dna templated GO:0006355 374 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
regulation of neurogenesis GO:0050767 247 0.025
cellular response to nitrogen compound GO:1901699 210 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
nucleotide metabolic process GO:0009117 279 0.024
metal ion homeostasis GO:0055065 186 0.024
cell cell signaling GO:0007267 335 0.024
peptidyl amino acid modification GO:0018193 126 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
cellular catabolic process GO:0044248 295 0.024
anterior posterior pattern specification GO:0009952 1 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
cation transmembrane transport GO:0098655 263 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
ras protein signal transduction GO:0007265 29 0.024
macromolecule localization GO:0033036 252 0.024
purine containing compound metabolic process GO:0072521 253 0.024
ion transmembrane transport GO:0034220 365 0.024
intracellular transport GO:0046907 185 0.024
positive regulation of phosphorylation GO:0042327 177 0.023
regulation of cellular component movement GO:0051270 150 0.023
single organism biosynthetic process GO:0044711 342 0.023
negative regulation of cell death GO:0060548 229 0.023
aging GO:0007568 241 0.023
single organism cellular localization GO:1902580 102 0.023
regulation of locomotion GO:0040012 148 0.023
cellular chemical homeostasis GO:0055082 247 0.023
nucleic acid templated transcription GO:0097659 379 0.023
cellular component morphogenesis GO:0032989 155 0.023
transmembrane transport GO:0055085 412 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
neurological system process GO:0050877 219 0.022
negative regulation of gene expression GO:0010629 199 0.022
regulation of hormone levels GO:0010817 187 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
protein oligomerization GO:0051259 191 0.022
metal ion transport GO:0030001 289 0.022
chemical homeostasis GO:0048878 292 0.022
inorganic ion transmembrane transport GO:0098660 229 0.022
cellular protein localization GO:0034613 122 0.022
organic substance catabolic process GO:1901575 316 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
brain development GO:0007420 247 0.022
cytokine mediated signaling pathway GO:0019221 43 0.021
cellular ion homeostasis GO:0006873 184 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
glycosyl compound metabolic process GO:1901657 182 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.021
immune response GO:0006955 104 0.021
mapk cascade GO:0000165 140 0.021
response to nutrient GO:0007584 248 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
cellular response to stress GO:0033554 269 0.020
protein localization GO:0008104 191 0.020
regulation of cellular localization GO:0060341 263 0.020
negative regulation of rna metabolic process GO:0051253 123 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
response to cytokine GO:0034097 215 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
response to glucocorticoid GO:0051384 223 0.019
gastrulation GO:0007369 2 0.019
negative regulation of cell communication GO:0010648 158 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
single organism intracellular transport GO:1902582 166 0.019
cellular lipid metabolic process GO:0044255 208 0.019
regulation of neuron projection development GO:0010975 161 0.019
regulation of cell proliferation GO:0042127 359 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
positive regulation of protein modification process GO:0031401 142 0.018
negative regulation of transcription dna templated GO:0045892 116 0.018
reproduction GO:0000003 245 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
motor neuron axon guidance GO:0008045 1 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
cellular cation homeostasis GO:0030003 180 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
negative regulation of transport GO:0051051 136 0.018
single organism behavior GO:0044708 130 0.018
cell part morphogenesis GO:0032990 123 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
negative regulation of molecular function GO:0044092 133 0.018
positive regulation of nervous system development GO:0051962 178 0.018
chromosome segregation GO:0007059 2 0.018
reproductive process GO:0022414 372 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
central nervous system neuron axonogenesis GO:0021955 1 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.017
regulation of small gtpase mediated signal transduction GO:0051056 48 0.017
response to external biotic stimulus GO:0043207 221 0.017
cellular homeostasis GO:0019725 252 0.017
response to wounding GO:0009611 254 0.017
response to oxygen levels GO:0070482 265 0.017
positive regulation of cell development GO:0010720 176 0.017
cell projection morphogenesis GO:0048858 123 0.017
embryonic pattern specification GO:0009880 1 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
regulation of synaptic transmission GO:0050804 141 0.017
nitrogen compound transport GO:0071705 229 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
response to corticosteroid GO:0031960 235 0.017
regulation of protein kinase activity GO:0045859 105 0.017
positive regulation of neurogenesis GO:0050769 165 0.016
proteolysis GO:0006508 175 0.016
cation homeostasis GO:0055080 195 0.016
regulation of protein localization GO:0032880 81 0.016
cellular response to peptide GO:1901653 133 0.016
bmp signaling pathway GO:0030509 4 0.016
nucleoside metabolic process GO:0009116 179 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
regulation of establishment of protein localization GO:0070201 69 0.016
response to other organism GO:0051707 220 0.016
regulation of cell motility GO:2000145 131 0.016
regulation of cell projection organization GO:0031344 175 0.016
adult locomotory behavior GO:0008344 4 0.016
cytoplasmic transport GO:0016482 115 0.016
oxidation reduction process GO:0055114 304 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
anion transport GO:0006820 178 0.015
negative regulation of developmental process GO:0051093 125 0.015
regulation of establishment of planar polarity GO:0090175 2 0.015
circulatory system process GO:0003013 183 0.015
response to peptide GO:1901652 292 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
growth GO:0040007 165 0.015
negative regulation of signal transduction GO:0009968 83 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
response to oxidative stress GO:0006979 186 0.015
regulation of programmed cell death GO:0043067 341 0.015
establishment of protein localization GO:0045184 141 0.015
cellular response to external stimulus GO:0071496 118 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
defense response GO:0006952 194 0.015
secretion by cell GO:0032940 248 0.015
regulation of kinase activity GO:0043549 117 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
response to peptide hormone GO:0043434 278 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
cellular macromolecule localization GO:0070727 122 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
response to carbohydrate GO:0009743 183 0.014
response to decreased oxygen levels GO:0036293 237 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
epithelium development GO:0060429 96 0.014
multicellular organism reproduction GO:0032504 233 0.014
calcium ion homeostasis GO:0055074 162 0.014
chemosensory behavior GO:0007635 2 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
response to insulin GO:0032868 133 0.014
axis specification GO:0009798 4 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
synaptic transmission GO:0007268 235 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
response to inorganic substance GO:0010035 377 0.014
cell type specific apoptotic process GO:0097285 134 0.014
protein heterooligomerization GO:0051291 89 0.013
response to estradiol GO:0032355 164 0.013
axon development GO:0061564 96 0.013
single organism organelle organization GO:1902589 180 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
regulation of catabolic process GO:0009894 113 0.013
response to biotic stimulus GO:0009607 226 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
response to toxic substance GO:0009636 133 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
axonogenesis GO:0007409 71 0.013
sex differentiation GO:0007548 113 0.013
cellular response to oxidative stress GO:0034599 76 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
response to acid chemical GO:0001101 222 0.013
eye morphogenesis GO:0048592 4 0.013
divalent inorganic cation transport GO:0072511 134 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
positive regulation of cell migration GO:0030335 96 0.013
epithelial cell differentiation GO:0030855 71 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
response to metal ion GO:0010038 253 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
positive regulation of cell death GO:0010942 184 0.013
heterocycle catabolic process GO:0046700 167 0.013
single organism reproductive process GO:0044702 297 0.013
positive regulation of rna metabolic process GO:0051254 203 0.012
neuron projection morphogenesis GO:0048812 122 0.012
actin filament based process GO:0030029 86 0.012
macromolecule catabolic process GO:0009057 58 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
organ formation GO:0048645 3 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
stress activated protein kinase signaling cascade GO:0031098 37 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
protein autophosphorylation GO:0046777 66 0.012
chromosome organization GO:0051276 36 0.012
development of primary sexual characteristics GO:0045137 107 0.012
regulation of transferase activity GO:0051338 123 0.012
regulation of hydrolase activity GO:0051336 143 0.012
signal release GO:0023061 145 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
peptide transport GO:0015833 97 0.012
gonad development GO:0008406 104 0.012
protein transport GO:0015031 132 0.012
secretion GO:0046903 307 0.012
regulation of response to stress GO:0080134 126 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
chromatin organization GO:0006325 34 0.012
olfactory behavior GO:0042048 2 0.012
carbohydrate metabolic process GO:0005975 130 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
developmental process involved in reproduction GO:0003006 159 0.012
response to hypoxia GO:0001666 231 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
positive regulation of kinase activity GO:0033674 77 0.011
cell growth GO:0016049 104 0.011
nucleotide catabolic process GO:0009166 139 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
response to ketone GO:1901654 182 0.011
organic anion transport GO:0015711 132 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
gamete generation GO:0007276 124 0.011
multi organism reproductive process GO:0044703 262 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
cell cycle GO:0007049 101 0.011
positive regulation of cell motility GO:2000147 97 0.011
positive regulation of transport GO:0051050 245 0.011
establishment of tissue polarity GO:0007164 2 0.011
sensory perception GO:0007600 101 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
aromatic compound catabolic process GO:0019439 168 0.011
camp metabolic process GO:0046058 63 0.011
mitotic spindle organization GO:0007052 2 0.011
cytokine biosynthetic process GO:0042089 3 0.011
response to lipopolysaccharide GO:0032496 191 0.011
response to ethanol GO:0045471 162 0.011
gtp catabolic process GO:0006184 71 0.011
response to alkaloid GO:0043279 132 0.011
reproductive structure development GO:0048608 128 0.011
positive regulation of gene expression GO:0010628 244 0.011
head development GO:0060322 247 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
salivary gland development GO:0007431 3 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
regulation of cellular response to stress GO:0080135 49 0.011
regeneration GO:0031099 163 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
response to vitamin GO:0033273 131 0.010
cytoskeleton dependent cytokinesis GO:0061640 2 0.010
cardiovascular system development GO:0072358 134 0.010
cell adhesion GO:0007155 110 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
regulation of neuron death GO:1901214 115 0.010
organ regeneration GO:0031100 101 0.010
positive regulation of locomotion GO:0040017 102 0.010
circulatory system development GO:0072359 134 0.010
regulation of transporter activity GO:0032409 50 0.010
regulation of system process GO:0044057 208 0.010
nuclear import GO:0051170 35 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
blood circulation GO:0008015 183 0.010
hormone secretion GO:0046879 115 0.010
rhythmic process GO:0048511 156 0.010
potassium ion transport GO:0006813 97 0.010
behavioral response to ethanol GO:0048149 1 0.010
regulation of secretion by cell GO:1903530 208 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
response to glucose GO:0009749 136 0.010

Hs2st1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
disease of metabolism DOID:0014667 0 0.012