Rattus norvegicus

64 known processes

Npm2

nucleophosmin/nucleoplasmin 2

Npm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
reproductive process GO:0022414 372 0.042
cellular response to oxygen containing compound GO:1901701 386 0.039
response to nutrient levels GO:0031667 370 0.039
cellular component biogenesis GO:0044085 368 0.038
response to inorganic substance GO:0010035 377 0.038
nucleic acid templated transcription GO:0097659 379 0.037
response to extracellular stimulus GO:0009991 380 0.036
programmed cell death GO:0012501 392 0.036
Rat
organic acid metabolic process GO:0006082 292 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.035
neuron differentiation GO:0030182 368 0.035
cellular response to endogenous stimulus GO:0071495 377 0.034
apoptotic process GO:0006915 381 0.034
Rat
cellular component assembly GO:0022607 360 0.034
single organism reproductive process GO:0044702 297 0.033
protein phosphorylation GO:0006468 345 0.032
response to oxygen levels GO:0070482 265 0.032
secretion GO:0046903 307 0.032
regulation of apoptotic process GO:0042981 335 0.031
Rat
oxoacid metabolic process GO:0043436 290 0.031
regulation of multicellular organismal development GO:2000026 376 0.031
negative regulation of metabolic process GO:0009892 331 0.031
intracellular signal transduction GO:0035556 314 0.030
regulation of cellular component organization GO:0051128 368 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
carboxylic acid metabolic process GO:0019752 289 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.029
homeostatic process GO:0042592 331 0.029
regulation of phosphate metabolic process GO:0019220 349 0.029
cellular catabolic process GO:0044248 295 0.029
rna biosynthetic process GO:0032774 380 0.029
regulation of transcription dna templated GO:0006355 374 0.029
regulation of molecular function GO:0065009 398 0.028
regulation of protein metabolic process GO:0051246 289 0.028
regulation of programmed cell death GO:0043067 341 0.028
Rat
cation transport GO:0006812 382 0.028
response to decreased oxygen levels GO:0036293 237 0.027
reproduction GO:0000003 245 0.027
regulation of cell proliferation GO:0042127 359 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
positive regulation of transport GO:0051050 245 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
multicellular organismal reproductive process GO:0048609 233 0.027
chemical homeostasis GO:0048878 292 0.027
regulation of cell differentiation GO:0045595 320 0.027
rna metabolic process GO:0016070 406 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
response to metal ion GO:0010038 253 0.027
organic substance catabolic process GO:1901575 316 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
macromolecular complex assembly GO:0065003 273 0.026
cellular homeostasis GO:0019725 252 0.026
cellular chemical homeostasis GO:0055082 247 0.025
organophosphate metabolic process GO:0019637 370 0.025
central nervous system development GO:0007417 311 0.025
regulation of rna metabolic process GO:0051252 391 0.025
response to hypoxia GO:0001666 231 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
regulation of signal transduction GO:0009966 318 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
protein complex biogenesis GO:0070271 263 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
cellular amine metabolic process GO:0044106 38 0.025
neurological system process GO:0050877 219 0.025
regulation of catalytic activity GO:0050790 304 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
multicellular organism reproduction GO:0032504 233 0.024
neuron projection development GO:0031175 273 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
neuron development GO:0048666 286 0.024
single organism catabolic process GO:0044712 283 0.024
multi organism reproductive process GO:0044703 262 0.024
tissue development GO:0009888 252 0.024
response to acid chemical GO:0001101 222 0.024
response to corticosteroid GO:0031960 235 0.024
cellular ketone metabolic process GO:0042180 51 0.024
cell projection organization GO:0030030 302 0.024
protein complex subunit organization GO:0071822 302 0.024
catabolic process GO:0009056 351 0.024
cellular response to organic cyclic compound GO:0071407 202 0.024
response to nutrient GO:0007584 248 0.024
amine metabolic process GO:0009308 38 0.023
cell cell signaling GO:0007267 335 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
protein complex assembly GO:0006461 263 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
ion homeostasis GO:0050801 212 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
positive regulation of developmental process GO:0051094 283 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
secretion by cell GO:0032940 248 0.023
transcription dna templated GO:0006351 377 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
regulation of protein modification process GO:0031399 194 0.023
response to growth factor GO:0070848 189 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
aging GO:0007568 241 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
response to peptide GO:1901652 292 0.023
regulation of nervous system development GO:0051960 264 0.023
response to peptide hormone GO:0043434 278 0.022
response to wounding GO:0009611 254 0.022
metal ion transport GO:0030001 289 0.022
transmembrane transport GO:0055085 412 0.022
macromolecule localization GO:0033036 252 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
response to estrogen GO:0043627 232 0.022
regulation of system process GO:0044057 208 0.022
positive regulation of molecular function GO:0044093 230 0.022
negative regulation of gene expression GO:0010629 199 0.022
regulation of neurogenesis GO:0050767 247 0.022
regulation of cellular localization GO:0060341 263 0.022
single organism biosynthetic process GO:0044711 342 0.022
cellular response to lipid GO:0071396 201 0.022
brain development GO:0007420 247 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
head development GO:0060322 247 0.021
regulation of cell development GO:0060284 263 0.021
organelle organization GO:0006996 266 0.021
nucleotide metabolic process GO:0009117 279 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
developmental process involved in reproduction GO:0003006 159 0.021
proteolysis GO:0006508 175 0.021
ion transmembrane transport GO:0034220 365 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
response to glucocorticoid GO:0051384 223 0.020
regulation of secretion GO:0051046 224 0.020
cellular response to stress GO:0033554 269 0.020
circulatory system process GO:0003013 183 0.020
regulation of secretion by cell GO:1903530 208 0.020
regulation of neuron differentiation GO:0045664 208 0.020
response to carbohydrate GO:0009743 183 0.019
cellular ion homeostasis GO:0006873 184 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
negative regulation of cell death GO:0060548 229 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
cation homeostasis GO:0055080 195 0.019
regulation of phosphorylation GO:0042325 248 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
regulation of hormone levels GO:0010817 187 0.019
purine containing compound metabolic process GO:0072521 253 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
protein oligomerization GO:0051259 191 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
positive regulation of cell communication GO:0010647 271 0.018
response to ketone GO:1901654 182 0.018
response to hexose GO:0009746 144 0.018
positive regulation of signaling GO:0023056 270 0.018
regulation of cell projection organization GO:0031344 175 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
response to monosaccharide GO:0034284 159 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
blood circulation GO:0008015 183 0.018
cellular cation homeostasis GO:0030003 180 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
positive regulation of gene expression GO:0010628 244 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
rhythmic process GO:0048511 156 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
lipid metabolic process GO:0006629 283 0.017
protein localization GO:0008104 191 0.017
metal ion homeostasis GO:0055065 186 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
signal release GO:0023061 145 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
sexual reproduction GO:0019953 148 0.017
cellular component movement GO:0006928 248 0.017
positive regulation of nervous system development GO:0051962 178 0.017
reproductive structure development GO:0048608 128 0.017
nitrogen compound transport GO:0071705 229 0.017
reproductive system development GO:0061458 128 0.017
response to estradiol GO:0032355 164 0.017
response to oxidative stress GO:0006979 186 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
purine nucleotide metabolic process GO:0006163 229 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
growth GO:0040007 165 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
calcium ion homeostasis GO:0055074 162 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
response to biotic stimulus GO:0009607 226 0.016
behavior GO:0007610 205 0.016
muscle system process GO:0003012 115 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
gland development GO:0048732 155 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
anterior posterior pattern specification GO:0009952 1 0.016
positive regulation of protein modification process GO:0031401 142 0.016
oxidation reduction process GO:0055114 304 0.016
positive regulation of cell death GO:0010942 184 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
gamete generation GO:0007276 124 0.015
response to vitamin GO:0033273 131 0.015
regeneration GO:0031099 163 0.015
axis specification GO:0009798 4 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
synaptic transmission GO:0007268 235 0.015
regulation of ion transport GO:0043269 245 0.015
response to external biotic stimulus GO:0043207 221 0.015
calcium ion transport GO:0006816 131 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
positive regulation of cell development GO:0010720 176 0.015
vesicle mediated transport GO:0016192 181 0.015
response to glucose GO:0009749 136 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
locomotion GO:0040011 237 0.015
single organism organelle organization GO:1902589 180 0.015
cellular component morphogenesis GO:0032989 155 0.015
sex differentiation GO:0007548 113 0.015
intracellular transport GO:0046907 185 0.015
defense response GO:0006952 194 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
cellular lipid metabolic process GO:0044255 208 0.015
ras protein signal transduction GO:0007265 29 0.015
response to radiation GO:0009314 137 0.015
cation transmembrane transport GO:0098655 263 0.015
response to bacterium GO:0009617 200 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
regulation of hydrolase activity GO:0051336 143 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
localization of cell GO:0051674 202 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
response to alkaloid GO:0043279 132 0.014
regulation of neuron projection development GO:0010975 161 0.014
positive regulation of secretion GO:0051047 140 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
negative regulation of cell communication GO:0010648 158 0.014
response to other organism GO:0051707 220 0.014
anion transport GO:0006820 178 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
gastrulation GO:0007369 2 0.014
hormone transport GO:0009914 121 0.014
heterocycle catabolic process GO:0046700 167 0.014
negative regulation of signaling GO:0023057 157 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
nucleoside metabolic process GO:0009116 179 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
multi multicellular organism process GO:0044706 138 0.014
organonitrogen compound catabolic process GO:1901565 179 0.013
regulation of hormone secretion GO:0046883 106 0.013
negative regulation of transport GO:0051051 136 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
cell migration GO:0016477 197 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
negative regulation of innate immune response GO:0045824 4 0.013
response to ethanol GO:0045471 162 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
response to purine containing compound GO:0014074 126 0.013
response to cytokine GO:0034097 215 0.013
heart morphogenesis GO:0003007 3 0.013
response to lipopolysaccharide GO:0032496 191 0.013
regulation of membrane potential GO:0042391 110 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
circulatory system development GO:0072359 134 0.013
single organism intracellular transport GO:1902582 166 0.013
regulation of anatomical structure size GO:0090066 135 0.013
development of primary sexual characteristics GO:0045137 107 0.013
response to toxic substance GO:0009636 133 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
cell motility GO:0048870 202 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
epithelium development GO:0060429 96 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
single organism behavior GO:0044708 130 0.012
gonad development GO:0008406 104 0.012
aromatic compound catabolic process GO:0019439 168 0.012
regulation of synaptic transmission GO:0050804 141 0.012
cell morphogenesis GO:0000902 142 0.012
developmental growth GO:0048589 100 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
divalent inorganic cation transport GO:0072511 134 0.012
wound healing GO:0042060 122 0.012
carbohydrate metabolic process GO:0005975 130 0.012
embryonic pattern specification GO:0009880 1 0.012
hormone secretion GO:0046879 115 0.012
peptide transport GO:0015833 97 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
response to reactive oxygen species GO:0000302 120 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
divalent metal ion transport GO:0070838 132 0.012
regulation of mapk cascade GO:0043408 116 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
positive regulation of signal transduction GO:0009967 175 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
spermatogenesis GO:0007283 99 0.012
regulation of blood circulation GO:1903522 110 0.012
amide transport GO:0042886 105 0.012
male gamete generation GO:0048232 99 0.012
neuron death GO:0070997 127 0.012
Rat
immune system process GO:0002376 204 0.012
cell part morphogenesis GO:0032990 123 0.012
cell type specific apoptotic process GO:0097285 134 0.012
Rat
positive regulation of cell projection organization GO:0031346 111 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
regulation of body fluid levels GO:0050878 90 0.011
dna metabolic process GO:0006259 96 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
female pregnancy GO:0007565 122 0.011
cardiovascular system development GO:0072358 134 0.011
regulation of neuron death GO:1901214 115 0.011
Rat
cytoplasmic transport GO:0016482 115 0.011
eye morphogenesis GO:0048592 4 0.011
cellular response to acid chemical GO:0071229 75 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
protein homooligomerization GO:0051260 91 0.011
negative regulation of molecular function GO:0044092 133 0.011
lipid storage GO:0019915 1 0.011
epithelial cell differentiation GO:0030855 71 0.011
circadian rhythm GO:0007623 88 0.011
action potential GO:0001508 54 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
cellular protein localization GO:0034613 122 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
cellular response to external stimulus GO:0071496 118 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
purine containing compound catabolic process GO:0072523 138 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
transmission of nerve impulse GO:0019226 42 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
regulation of transferase activity GO:0051338 123 0.011
muscle contraction GO:0006936 88 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
chemosensory behavior GO:0007635 2 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
response to retinoic acid GO:0032526 63 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
multicellular organism growth GO:0035264 1 0.010
hepaticobiliary system development GO:0061008 90 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
organ regeneration GO:0031100 101 0.010
regulation of blood vessel size GO:0050880 89 0.010
regulation of kinase activity GO:0043549 117 0.010
cellular response to alcohol GO:0097306 87 0.010
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.010
response to organophosphorus GO:0046683 102 0.010
organophosphate catabolic process GO:0046434 148 0.010
peptidyl amino acid modification GO:0018193 126 0.010
salivary gland development GO:0007431 3 0.010
peptide hormone secretion GO:0030072 84 0.010
establishment of protein localization GO:0045184 141 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
neuron projection morphogenesis GO:0048812 122 0.010
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.010
limb morphogenesis GO:0035108 4 0.010
protein transport GO:0015031 132 0.010
neuronal action potential GO:0019228 35 0.010
sensory perception GO:0007600 101 0.010
chromosome segregation GO:0007059 2 0.010
multicellular organismal signaling GO:0035637 44 0.010
sequestering of calcium ion GO:0051208 8 0.010

Npm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
sensory system disease DOID:0050155 0 0.021
musculoskeletal system disease DOID:17 0 0.019
disease of metabolism DOID:0014667 0 0.014
eye disease DOID:5614 0 0.014
retinal disease DOID:5679 0 0.014
eye and adnexa disease DOID:1492 0 0.014
retinal degeneration DOID:8466 0 0.011
connective tissue disease DOID:65 0 0.010
central nervous system disease DOID:331 0 0.010