Rattus norvegicus

20 known processes

Mylpf

myosin light chain, phosphorylatable, fast skeletal muscle

(Aliases: MLC2,Myolc1,Myl2)

Mylpf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue development GO:0009888 252 0.331
muscle system process GO:0003012 115 0.276
Worm
striated muscle contraction GO:0006941 44 0.221
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.205
nucleotide catabolic process GO:0009166 139 0.202
musculoskeletal movement GO:0050881 17 0.202
glycosyl compound metabolic process GO:1901657 182 0.199
muscle tissue development GO:0060537 58 0.177
single organism organelle organization GO:1902589 180 0.173
purine nucleotide metabolic process GO:0006163 229 0.171
muscle contraction GO:0006936 88 0.169
Worm
ribonucleotide catabolic process GO:0009261 136 0.165
actin filament based process GO:0030029 86 0.162
purine ribonucleotide metabolic process GO:0009150 227 0.148
aromatic compound catabolic process GO:0019439 168 0.146
atp catabolic process GO:0006200 54 0.136
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.129
organic substance catabolic process GO:1901575 316 0.126
actin cytoskeleton organization GO:0030036 73 0.122
cellular catabolic process GO:0044248 295 0.112
actin myosin filament sliding GO:0033275 2 0.109
purine ribonucleoside metabolic process GO:0046128 168 0.105
cellular nitrogen compound catabolic process GO:0044270 163 0.105
skeletal muscle tissue development GO:0007519 31 0.100
actin crosslink formation GO:0051764 3 0.097
nucleoside phosphate metabolic process GO:0006753 283 0.095
catabolic process GO:0009056 351 0.093
carbohydrate derivative metabolic process GO:1901135 346 0.091
response to metal ion GO:0010038 253 0.090
purine nucleoside triphosphate catabolic process GO:0009146 122 0.089
oxoacid metabolic process GO:0043436 290 0.088
organelle organization GO:0006996 266 0.087
muscle filament sliding GO:0030049 2 0.084
nucleotide metabolic process GO:0009117 279 0.084
organonitrogen compound catabolic process GO:1901565 179 0.083
ribonucleoside triphosphate metabolic process GO:0009199 141 0.080
carboxylic acid metabolic process GO:0019752 289 0.079
purine nucleoside metabolic process GO:0042278 169 0.079
actin filament based movement GO:0030048 16 0.079
rna metabolic process GO:0016070 406 0.078
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.078
cardiac muscle contraction GO:0060048 27 0.077
ribonucleoside metabolic process GO:0009119 174 0.076
cellular component biogenesis GO:0044085 368 0.076
purine nucleoside monophosphate catabolic process GO:0009128 55 0.073
response to wounding GO:0009611 254 0.071
nucleobase containing small molecule metabolic process GO:0055086 316 0.071
macromolecular complex subunit organization GO:0043933 339 0.070
purine nucleoside catabolic process GO:0006152 124 0.068
nucleoside triphosphate metabolic process GO:0009141 144 0.067
anatomical structure morphogenesis GO:0009653 298 0.066
twitch skeletal muscle contraction GO:0014721 3 0.066
atp metabolic process GO:0046034 72 0.065
nucleoside metabolic process GO:0009116 179 0.064
intracellular transport GO:0046907 185 0.062
voluntary skeletal muscle contraction GO:0003010 3 0.061
circulatory system process GO:0003013 183 0.061
nucleoside catabolic process GO:0009164 126 0.061
regulation of nucleic acid templated transcription GO:1903506 380 0.059
purine containing compound metabolic process GO:0072521 253 0.059
heterocycle catabolic process GO:0046700 167 0.058
organophosphate metabolic process GO:0019637 370 0.058
cellular component morphogenesis GO:0032989 155 0.058
purine containing compound catabolic process GO:0072523 138 0.057
purine nucleoside monophosphate metabolic process GO:0009126 84 0.057
ribonucleoside triphosphate catabolic process GO:0009203 122 0.057
response to hypoxia GO:0001666 231 0.056
carbohydrate derivative catabolic process GO:1901136 147 0.056
slow twitch skeletal muscle fiber contraction GO:0031444 2 0.055
response to external biotic stimulus GO:0043207 221 0.055
striated muscle tissue development GO:0014706 58 0.053
response to extracellular stimulus GO:0009991 380 0.053
multicellular organism reproduction GO:0032504 233 0.050
Worm
nucleoside triphosphate catabolic process GO:0009143 123 0.050
nucleoside monophosphate catabolic process GO:0009125 56 0.048
regulation of rna metabolic process GO:0051252 391 0.047
protein complex subunit organization GO:0071822 302 0.047
nucleoside monophosphate metabolic process GO:0009123 93 0.046
cellular component assembly GO:0022607 360 0.046
chemical homeostasis GO:0048878 292 0.045
nucleoside phosphate catabolic process GO:1901292 140 0.045
ribose phosphate metabolic process GO:0019693 235 0.045
cytoskeleton organization GO:0007010 111 0.044
single organism catabolic process GO:0044712 283 0.044
rna biosynthetic process GO:0032774 380 0.044
ribonucleoside monophosphate catabolic process GO:0009158 55 0.044
regulation of sarcomere organization GO:0060297 2 0.043
glycosyl compound catabolic process GO:1901658 126 0.042
regulation of system process GO:0044057 208 0.042
Worm
organic cyclic compound catabolic process GO:1901361 175 0.041
muscle structure development GO:0061061 87 0.041
reproduction GO:0000003 245 0.041
Worm
positive regulation of rna metabolic process GO:0051254 203 0.041
purine ribonucleoside catabolic process GO:0046130 124 0.040
nitrogen compound transport GO:0071705 229 0.039
purine ribonucleotide catabolic process GO:0009154 136 0.039
regulation of cellular localization GO:0060341 263 0.038
anatomical structure formation involved in morphogenesis GO:0048646 83 0.038
multi organism reproductive process GO:0044703 262 0.038
Worm
cellular response to oxygen containing compound GO:1901701 386 0.038
regulation of rna biosynthetic process GO:2001141 381 0.037
muscle organ development GO:0007517 50 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.037
ribonucleoside monophosphate metabolic process GO:0009161 88 0.037
organic acid metabolic process GO:0006082 292 0.036
cellular protein localization GO:0034613 122 0.036
myosin filament organization GO:0031033 2 0.036
protein complex biogenesis GO:0070271 263 0.036
cellular amino acid biosynthetic process GO:0008652 32 0.036
regulation of muscle contraction GO:0006937 53 0.035
Worm
protein complex assembly GO:0006461 263 0.035
regulation of cellular component organization GO:0051128 368 0.035
cell morphogenesis involved in differentiation GO:0000904 119 0.034
response to oxygen levels GO:0070482 265 0.034
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.033
single organism biosynthetic process GO:0044711 342 0.033
response to hexose GO:0009746 144 0.033
muscle cell differentiation GO:0042692 52 0.032
cellular modified amino acid biosynthetic process GO:0042398 18 0.032
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
cellular component assembly involved in morphogenesis GO:0010927 17 0.031
response to lipopolysaccharide GO:0032496 191 0.031
nucleobase containing compound catabolic process GO:0034655 152 0.030
growth GO:0040007 165 0.030
muscle organ morphogenesis GO:0048644 1 0.029
amine metabolic process GO:0009308 38 0.029
sensory organ development GO:0007423 74 0.028
transmembrane transport GO:0055085 412 0.028
myosin filament assembly GO:0031034 1 0.028
regulation of transcription dna templated GO:0006355 374 0.028
ribonucleotide metabolic process GO:0009259 231 0.028
multicellular organismal reproductive process GO:0048609 233 0.027
Worm
negative regulation of metabolic process GO:0009892 331 0.027
purine nucleoside triphosphate metabolic process GO:0009144 141 0.027
homeostatic process GO:0042592 331 0.027
camera type eye development GO:0043010 48 0.027
cellular ion homeostasis GO:0006873 184 0.027
skeletal muscle contraction GO:0003009 17 0.026
blood circulation GO:0008015 183 0.026
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.026
ion transmembrane transport GO:0034220 365 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
purine nucleotide catabolic process GO:0006195 136 0.026
response to peptide GO:1901652 292 0.026
organophosphate catabolic process GO:0046434 148 0.026
single organism intracellular transport GO:1902582 166 0.026
heart morphogenesis GO:0003007 3 0.025
monosaccharide metabolic process GO:0005996 61 0.025
embryonic skeletal system development GO:0048706 3 0.025
regulation of cell morphogenesis GO:0022604 77 0.025
nucleotide transmembrane transport GO:1901679 2 0.025
response to estrogen GO:0043627 232 0.025
cell projection organization GO:0030030 302 0.025
response to heat GO:0009408 60 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
head development GO:0060322 247 0.024
hepaticobiliary system development GO:0061008 90 0.024
gland development GO:0048732 155 0.023
nucleic acid templated transcription GO:0097659 379 0.023
response to inorganic substance GO:0010035 377 0.023
positive regulation of developmental process GO:0051094 283 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
neuron differentiation GO:0030182 368 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
striated muscle cell differentiation GO:0051146 39 0.022
heart contraction GO:0060047 57 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
cellular modified amino acid metabolic process GO:0006575 61 0.022
macromolecular complex assembly GO:0065003 273 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
regulation of neuron projection development GO:0010975 161 0.021
actomyosin structure organization GO:0031032 22 0.021
response to nutrient GO:0007584 248 0.021
response to peptide hormone GO:0043434 278 0.021
regulation of ion transport GO:0043269 245 0.021
gastrulation GO:0007369 2 0.020
eye development GO:0001654 50 0.020
negative regulation of gene expression GO:0010629 199 0.019
response to interleukin 1 GO:0070555 55 0.019
cellular chemical homeostasis GO:0055082 247 0.019
ribonucleoside catabolic process GO:0042454 126 0.019
liver development GO:0001889 90 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
multicellular organismal movement GO:0050879 17 0.019
regulation of secretion by cell GO:1903530 208 0.019
regulation of molecular function GO:0065009 398 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
cellular macromolecular complex assembly GO:0034622 58 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
cellular component movement GO:0006928 248 0.019
organophosphate biosynthetic process GO:0090407 143 0.018
calcium ion transport GO:0006816 131 0.018
sequestering of calcium ion GO:0051208 8 0.018
striated muscle cell development GO:0055002 26 0.018
organic acid biosynthetic process GO:0016053 83 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
protein oligomerization GO:0051259 191 0.018
positive regulation of gene expression GO:0010628 244 0.018
retina development in camera type eye GO:0060041 27 0.018
muscle cell proliferation GO:0033002 84 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
negative regulation of signaling GO:0023057 157 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
diaphragm contraction GO:0002086 2 0.016
regulation of cell differentiation GO:0045595 320 0.016
secretion by cell GO:0032940 248 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
apoptotic process GO:0006915 381 0.016
organ morphogenesis GO:0009887 75 0.016
cell cell signaling GO:0007267 335 0.016
regulation of cell development GO:0060284 263 0.016
mesoderm development GO:0007498 2 0.016
cellular protein complex assembly GO:0043623 44 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
epithelial cell proliferation GO:0050673 54 0.016
response to ethanol GO:0045471 162 0.015
anterior posterior pattern specification GO:0009952 1 0.015
rhythmic process GO:0048511 156 0.015
organelle assembly GO:0070925 22 0.015
response to ketone GO:1901654 182 0.015
heart development GO:0007507 72 0.015
epithelium development GO:0060429 96 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
actin mediated cell contraction GO:0070252 12 0.015
single organism reproductive process GO:0044702 297 0.015
negative regulation of cell communication GO:0010648 158 0.015
response to nutrient levels GO:0031667 370 0.015
brain development GO:0007420 247 0.015
response to glucose GO:0009749 136 0.015
regeneration GO:0031099 163 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
gamete generation GO:0007276 124 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
cardiac chamber development GO:0003205 1 0.015
skeletal muscle organ development GO:0060538 33 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.014
neural crest cell development GO:0014032 2 0.014
response to zinc ion GO:0010043 39 0.014
negative regulation of transport GO:0051051 136 0.014
cellular response to fluid shear stress GO:0071498 4 0.014
regulation of extracellular matrix constituent secretion GO:0003330 2 0.014
response to electrical stimulus GO:0051602 56 0.014
axon development GO:0061564 96 0.014
cellular amine metabolic process GO:0044106 38 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
axonogenesis GO:0007409 71 0.014
negative regulation of organ growth GO:0046621 3 0.014
sexual reproduction GO:0019953 148 0.013
cation transport GO:0006812 382 0.013
regulation of neuron differentiation GO:0045664 208 0.013
divalent metal ion transport GO:0070838 132 0.013
actin filament organization GO:0007015 42 0.013
divalent inorganic cation transport GO:0072511 134 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
renin angiotensin regulation of aldosterone production GO:0002018 3 0.013
cell growth GO:0016049 104 0.013
response to starvation GO:0042594 59 0.013
regulation of growth GO:0040008 105 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
cellular homeostasis GO:0019725 252 0.013
myoblast fusion GO:0007520 2 0.013
ovulation cycle GO:0042698 67 0.013
muscle cell development GO:0055001 26 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
carbohydrate metabolic process GO:0005975 130 0.013
positive regulation of signaling GO:0023056 270 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
response to monosaccharide GO:0034284 159 0.013
cardiac myofibril assembly GO:0055003 1 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.012
neuron projection morphogenesis GO:0048812 122 0.012
response to other organism GO:0051707 220 0.012
cardiac muscle tissue morphogenesis GO:0055008 1 0.012
regulation of cell growth GO:0001558 85 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
heart process GO:0003015 57 0.012
cellular response to interleukin 1 GO:0071347 37 0.012
regulation of muscle filament sliding GO:0032971 1 0.012
response to amino acid GO:0043200 75 0.012
response to biotic stimulus GO:0009607 226 0.012
reproductive process GO:0022414 372 0.012
Worm
negative regulation of cell death GO:0060548 229 0.012
programmed cell death GO:0012501 392 0.012
response to radiation GO:0009314 137 0.012
cell part morphogenesis GO:0032990 123 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
aging GO:0007568 241 0.012
tissue regeneration GO:0042246 36 0.012
erythrocyte differentiation GO:0030218 1 0.012
formation of primary germ layer GO:0001704 1 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
chordate embryonic development GO:0043009 18 0.011
cellular response to peptide GO:1901653 133 0.011
syncytium formation by plasma membrane fusion GO:0000768 3 0.011
central nervous system development GO:0007417 311 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of epithelial cell proliferation GO:0050680 16 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
developmental growth GO:0048589 100 0.011
hematopoietic or lymphoid organ development GO:0048534 36 0.011
response to activity GO:0014823 73 0.011
amide transport GO:0042886 105 0.011
palate development GO:0060021 2 0.011
transcription dna templated GO:0006351 377 0.011
organic acid catabolic process GO:0016054 49 0.011
regulation of signal transduction GO:0009966 318 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
regulation of cell projection organization GO:0031344 175 0.011
maintenance of location GO:0051235 17 0.011
axis specification GO:0009798 4 0.011
secretion GO:0046903 307 0.011
generation of precursor metabolites and energy GO:0006091 62 0.010
developmental process involved in reproduction GO:0003006 159 0.010
dicarboxylic acid metabolic process GO:0043648 42 0.010
regulation of apoptotic process GO:0042981 335 0.010
negative regulation of molecular function GO:0044092 133 0.010
regulation of ion homeostasis GO:2000021 63 0.010
embryonic skeletal system morphogenesis GO:0048704 3 0.010
cardiovascular system development GO:0072358 134 0.010
cation homeostasis GO:0055080 195 0.010
protein phosphorylation GO:0006468 345 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
sequestering of metal ion GO:0051238 9 0.010

Mylpf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.069
musculoskeletal system disease DOID:17 0 0.069
muscular disease DOID:0080000 0 0.050
muscle tissue disease DOID:66 0 0.050
nervous system disease DOID:863 0 0.020
myopathy DOID:423 0 0.018
heart disease DOID:114 0 0.018
cardiomyopathy DOID:0050700 0 0.018
intrinsic cardiomyopathy DOID:0060036 0 0.018
cardiovascular system disease DOID:1287 0 0.018
sensory system disease DOID:0050155 0 0.011
disease of metabolism DOID:0014667 0 0.010