Rattus norvegicus

40 known processes

Aars

alanyl-tRNA synthetase

Aars biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
trna aminoacylation GO:0043039 3 0.379
amino acid activation GO:0043038 3 0.373
trna aminoacylation for protein translation GO:0006418 3 0.281
trna metabolic process GO:0006399 4 0.252
organic acid metabolic process GO:0006082 292 0.161
carboxylic acid metabolic process GO:0019752 289 0.149
cellular amino acid metabolic process GO:0006520 107 0.143
translation GO:0006412 35 0.130
oxoacid metabolic process GO:0043436 290 0.128
organophosphate metabolic process GO:0019637 370 0.086
nucleoside phosphate metabolic process GO:0006753 283 0.075
nucleotide metabolic process GO:0009117 279 0.072
mitochondrial rna metabolic process GO:0000959 1 0.070
nucleobase containing small molecule metabolic process GO:0055086 316 0.062
ncrna metabolic process GO:0034660 8 0.057
multicellular organism growth GO:0035264 1 0.050
cation transport GO:0006812 382 0.047
single organism biosynthetic process GO:0044711 342 0.045
regulation of apoptotic process GO:0042981 335 0.045
Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.043
cellular response to stress GO:0033554 269 0.042
Mouse
growth GO:0040007 165 0.042
response to nutrient levels GO:0031667 370 0.041
regulation of multicellular organismal development GO:2000026 376 0.041
intracellular signal transduction GO:0035556 314 0.040
apoptotic process GO:0006915 381 0.040
Mouse
metal ion transport GO:0030001 289 0.038
response to decreased oxygen levels GO:0036293 237 0.037
regulation of intracellular signal transduction GO:1902531 218 0.035
regulation of protein metabolic process GO:0051246 289 0.035
Mouse
regulation of cellular protein metabolic process GO:0032268 267 0.034
Mouse
carbohydrate derivative metabolic process GO:1901135 346 0.033
purine containing compound metabolic process GO:0072521 253 0.032
regulation of programmed cell death GO:0043067 341 0.032
Mouse
regulation of signal transduction GO:0009966 318 0.031
positive regulation of developmental process GO:0051094 283 0.031
aromatic compound catabolic process GO:0019439 168 0.030
macromolecule localization GO:0033036 252 0.029
central nervous system development GO:0007417 311 0.029
Mouse
amine metabolic process GO:0009308 38 0.029
regulation of cellular component organization GO:0051128 368 0.028
neuron differentiation GO:0030182 368 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
cellular amine metabolic process GO:0044106 38 0.028
regulation of cell differentiation GO:0045595 320 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
regulation of cell development GO:0060284 263 0.026
response to extracellular stimulus GO:0009991 380 0.026
nucleobase containing compound catabolic process GO:0034655 152 0.025
response to peptide GO:1901652 292 0.025
cellular component biogenesis GO:0044085 368 0.025
cellular catabolic process GO:0044248 295 0.025
reproduction GO:0000003 245 0.024
cation transmembrane transport GO:0098655 263 0.024
organelle organization GO:0006996 266 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
cellular response to oxygen containing compound GO:1901701 386 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
homeostatic process GO:0042592 331 0.023
cellular component movement GO:0006928 248 0.022
nucleoside metabolic process GO:0009116 179 0.022
transmembrane transport GO:0055085 412 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
response to other organism GO:0051707 220 0.022
ion transmembrane transport GO:0034220 365 0.022
positive regulation of response to stimulus GO:0048584 285 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
purine ribonucleoside catabolic process GO:0046130 124 0.021
programmed cell death GO:0012501 392 0.021
Mouse
organonitrogen compound catabolic process GO:1901565 179 0.021
nucleoside phosphate biosynthetic process GO:1901293 102 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
cellular ketone metabolic process GO:0042180 51 0.020
head development GO:0060322 247 0.020
Mouse
catabolic process GO:0009056 351 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
carbohydrate metabolic process GO:0005975 130 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
regulation of phosphate metabolic process GO:0019220 349 0.019
single organism intracellular transport GO:1902582 166 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
chemical homeostasis GO:0048878 292 0.019
single organism catabolic process GO:0044712 283 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
inorganic cation transmembrane transport GO:0098662 202 0.018
double strand break repair GO:0006302 1 0.018
positive regulation of gene expression GO:0010628 244 0.018
regulation of nervous system development GO:0051960 264 0.018
oxidation reduction process GO:0055114 304 0.018
ion homeostasis GO:0050801 212 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
response to nutrient GO:0007584 248 0.018
intracellular transport GO:0046907 185 0.017
protein localization GO:0008104 191 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
response to hypoxia GO:0001666 231 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
tissue development GO:0009888 252 0.017
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
regulation of neurogenesis GO:0050767 247 0.017
regulation of catalytic activity GO:0050790 304 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
organic substance catabolic process GO:1901575 316 0.016
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
sexual reproduction GO:0019953 148 0.016
response to inorganic substance GO:0010035 377 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
regulation of molecular function GO:0065009 398 0.016
positive regulation of cell death GO:0010942 184 0.016
response to oxygen levels GO:0070482 265 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
positive regulation of nervous system development GO:0051962 178 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of phosphorylation GO:0042325 248 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
Mouse
negative regulation of cell death GO:0060548 229 0.016
Mouse
diadenosine polyphosphate metabolic process GO:0015959 2 0.016
rna metabolic process GO:0016070 406 0.016
organic anion transport GO:0015711 132 0.015
brain development GO:0007420 247 0.015
Mouse
nucleic acid templated transcription GO:0097659 379 0.015
regulation of growth GO:0040008 105 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
single organism organelle organization GO:1902589 180 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
gastrulation GO:0007369 2 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
cellular protein localization GO:0034613 122 0.015
lipid metabolic process GO:0006629 283 0.015
protein complex subunit organization GO:0071822 302 0.015
cell projection organization GO:0030030 302 0.015
protein complex assembly GO:0006461 263 0.015
hepaticobiliary system development GO:0061008 90 0.015
neuron development GO:0048666 286 0.015
cellular component assembly GO:0022607 360 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
cellular response to endogenous stimulus GO:0071495 377 0.014
neural crest cell development GO:0014032 2 0.014
regulation of catabolic process GO:0009894 113 0.014
cardiovascular system development GO:0072358 134 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
regulation of rna metabolic process GO:0051252 391 0.014
macromolecular complex assembly GO:0065003 273 0.014
regulation of cell growth GO:0001558 85 0.014
organophosphate catabolic process GO:0046434 148 0.014
developmental growth GO:0048589 100 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
maintenance of location GO:0051235 17 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
positive regulation of signaling GO:0023056 270 0.013
positive regulation of molecular function GO:0044093 230 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
cellular chemical homeostasis GO:0055082 247 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
cellular ion homeostasis GO:0006873 184 0.013
neuron projection development GO:0031175 273 0.013
positive regulation of cell development GO:0010720 176 0.013
multicellular organism reproduction GO:0032504 233 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
negative regulation of developmental process GO:0051093 125 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
Mouse
protein phosphorylation GO:0006468 345 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
lipid storage GO:0019915 1 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
amino acid transport GO:0006865 70 0.013
cellular response to external stimulus GO:0071496 118 0.013
regulation of ion transport GO:0043269 245 0.013
carboxylic acid transport GO:0046942 115 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
cellular homeostasis GO:0019725 252 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
glycerolipid metabolic process GO:0046486 67 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
aging GO:0007568 241 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
rna biosynthetic process GO:0032774 380 0.012
eye morphogenesis GO:0048592 4 0.012
sex differentiation GO:0007548 113 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
transcription dna templated GO:0006351 377 0.012
regulation of protein modification process GO:0031399 194 0.012
negative regulation of transport GO:0051051 136 0.012
response to external biotic stimulus GO:0043207 221 0.012
neuron death GO:0070997 127 0.012
Mouse
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.012
nucleoside catabolic process GO:0009164 126 0.012
gamete generation GO:0007276 124 0.012
mitochondrion organization GO:0007005 35 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
protein complex biogenesis GO:0070271 263 0.012
branched chain amino acid transport GO:0015803 2 0.012
metal ion homeostasis GO:0055065 186 0.012
response to biotic stimulus GO:0009607 226 0.012
mapk cascade GO:0000165 140 0.012
nucleotide catabolic process GO:0009166 139 0.011
cation homeostasis GO:0055080 195 0.011
chromosome segregation GO:0007059 2 0.011
organic acid transport GO:0015849 116 0.011
atp metabolic process GO:0046034 72 0.011
response to metal ion GO:0010038 253 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
response to acid chemical GO:0001101 222 0.011
Mouse
regulation of neuron differentiation GO:0045664 208 0.011
purine containing compound catabolic process GO:0072523 138 0.011
circulatory system process GO:0003013 183 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
reproductive process GO:0022414 372 0.011
membrane organization GO:0061024 94 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
locomotion GO:0040011 237 0.011
negative regulation of signaling GO:0023057 157 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
multi organism reproductive process GO:0044703 262 0.011
coenzyme metabolic process GO:0006732 86 0.011
tube development GO:0035295 89 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
cellular response to peptide GO:1901653 133 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
nitrogen compound transport GO:0071705 229 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
alcohol metabolic process GO:0006066 77 0.010
response to oxidative stress GO:0006979 186 0.010
negative regulation of metabolic process GO:0009892 331 0.010
single organism reproductive process GO:0044702 297 0.010
regulation of membrane potential GO:0042391 110 0.010

Aars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.118
Human
disease of anatomical entity DOID:7 0 0.118
Human
charcot marie tooth disease DOID:10595 0 0.118
Human
nervous system disease DOID:863 0 0.118
Human
neuropathy DOID:870 0 0.118
Human
central nervous system disease DOID:331 0 0.017
disease of metabolism DOID:0014667 0 0.012
disease of cellular proliferation DOID:14566 0 0.011
sensory system disease DOID:0050155 0 0.010