Rattus norvegicus

129 known processes

Dnmt3a

DNA (cytosine-5-)-methyltransferase 3 alpha

(Aliases: MGC109195)

Dnmt3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.094
Rat
transcription dna templated GO:0006351 377 0.074
Rat
cell projection organization GO:0030030 302 0.057
regulation of rna metabolic process GO:0051252 391 0.057
Rat
nucleic acid templated transcription GO:0097659 379 0.054
Rat
regulation of programmed cell death GO:0043067 341 0.053
apoptotic process GO:0006915 381 0.051
programmed cell death GO:0012501 392 0.050
cell cell signaling GO:0007267 335 0.046
neuron differentiation GO:0030182 368 0.043
transcription from rna polymerase ii promoter GO:0006366 252 0.043
central nervous system development GO:0007417 311 0.042
regulation of rna biosynthetic process GO:2001141 381 0.041
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.041
brain development GO:0007420 247 0.039
regulation of cell differentiation GO:0045595 320 0.038
Rat
negative regulation of gene expression GO:0010629 199 0.037
Rat
positive regulation of response to stimulus GO:0048584 285 0.036
positive regulation of signaling GO:0023056 270 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.035
regulation of transcription dna templated GO:0006355 374 0.035
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.035
establishment of protein localization GO:0045184 141 0.035
protein phosphorylation GO:0006468 345 0.035
negative regulation of biosynthetic process GO:0009890 168 0.035
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
positive regulation of rna biosynthetic process GO:1902680 197 0.033
neuron projection development GO:0031175 273 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
head development GO:0060322 247 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
positive regulation of signal transduction GO:0009967 175 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
positive regulation of cell communication GO:0010647 271 0.031
macromolecule localization GO:0033036 252 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
cellular amine metabolic process GO:0044106 38 0.030
organelle organization GO:0006996 266 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
cellular ketone metabolic process GO:0042180 51 0.029
synaptic transmission GO:0007268 235 0.029
negative regulation of rna biosynthetic process GO:1902679 118 0.029
Rat
rna metabolic process GO:0016070 406 0.028
Rat
protein complex subunit organization GO:0071822 302 0.028
negative regulation of nucleic acid templated transcription GO:1903507 117 0.028
Rat
negative regulation of metabolic process GO:0009892 331 0.028
Rat
regulation of cellular component organization GO:0051128 368 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
Rat
response to nutrient levels GO:0031667 370 0.027
amine metabolic process GO:0009308 38 0.027
protein complex biogenesis GO:0070271 263 0.027
regulation of apoptotic process GO:0042981 335 0.027
negative regulation of apoptotic process GO:0043066 181 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
regulation of cell development GO:0060284 263 0.027
Rat
protein complex assembly GO:0006461 263 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
Rat
reproductive process GO:0022414 372 0.026
carboxylic acid metabolic process GO:0019752 289 0.026
neuron development GO:0048666 286 0.025
regulation of signal transduction GO:0009966 318 0.025
regulation of nucleic acid templated transcription GO:1903506 380 0.025
Rat
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.025
regulation of molecular function GO:0065009 398 0.025
regulation of protein metabolic process GO:0051246 289 0.025
cell part morphogenesis GO:0032990 123 0.025
positive regulation of biosynthetic process GO:0009891 319 0.024
protein transport GO:0015031 132 0.024
cellular component biogenesis GO:0044085 368 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.024
Rat
positive regulation of molecular function GO:0044093 230 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
Rat
secretion GO:0046903 307 0.023
negative regulation of rna metabolic process GO:0051253 123 0.023
Rat
positive regulation of developmental process GO:0051094 283 0.023
Rat
positive regulation of transcription dna templated GO:0045893 197 0.023
anterior posterior pattern specification GO:0009952 1 0.023
oxoacid metabolic process GO:0043436 290 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
cellular response to stress GO:0033554 269 0.022
regulation of cell proliferation GO:0042127 359 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.021
nucleoside metabolic process GO:0009116 179 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
Rat
cell projection morphogenesis GO:0048858 123 0.021
regulation of cellular localization GO:0060341 263 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.020
synaptic growth at neuromuscular junction GO:0051124 1 0.020
development of primary sexual characteristics GO:0045137 107 0.020
regulation of catalytic activity GO:0050790 304 0.020
axon development GO:0061564 96 0.020
axis specification GO:0009798 4 0.020
signal release GO:0023061 145 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
response to peptide GO:1901652 292 0.020
macromolecular complex assembly GO:0065003 273 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
regulation of nervous system development GO:0051960 264 0.020
Rat
response to cytokine GO:0034097 215 0.020
organic acid metabolic process GO:0006082 292 0.020
growth GO:0040007 165 0.020
regulation of secretion by cell GO:1903530 208 0.019
single organism reproductive process GO:0044702 297 0.019
embryonic pattern specification GO:0009880 1 0.019
intracellular signal transduction GO:0035556 314 0.019
protein localization GO:0008104 191 0.019
single organism catabolic process GO:0044712 283 0.019
neurological system process GO:0050877 219 0.019
regulation of response to external stimulus GO:0032101 106 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
regulation of protein modification process GO:0031399 194 0.019
multi organism reproductive process GO:0044703 262 0.019
eye morphogenesis GO:0048592 4 0.019
regulation of neurogenesis GO:0050767 247 0.019
Rat
multicellular organism reproduction GO:0032504 233 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
neuron projection morphogenesis GO:0048812 122 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
response to acid chemical GO:0001101 222 0.019
chemical homeostasis GO:0048878 292 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
biological adhesion GO:0022610 110 0.018
response to extracellular stimulus GO:0009991 380 0.018
rhythmic process GO:0048511 156 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
Rat
positive regulation of cellular component organization GO:0051130 200 0.018
single organism behavior GO:0044708 130 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
cellular component movement GO:0006928 248 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
positive regulation of gene expression GO:0010628 244 0.018
multicellular organismal reproductive process GO:0048609 233 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
response to inorganic substance GO:0010035 377 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
response to peptide hormone GO:0043434 278 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.017
gonad development GO:0008406 104 0.017
positive regulation of transport GO:0051050 245 0.017
regulation of cell projection organization GO:0031344 175 0.017
cellular chemical homeostasis GO:0055082 247 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
Rat
intracellular transport GO:0046907 185 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
chemosensory behavior GO:0007635 2 0.017
aging GO:0007568 241 0.017
cell morphogenesis GO:0000902 142 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
regulation of phosphorylation GO:0042325 248 0.016
negative regulation of cell death GO:0060548 229 0.016
reproduction GO:0000003 245 0.016
response to oxidative stress GO:0006979 186 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
response to reactive oxygen species GO:0000302 120 0.016
regulation of neuron projection development GO:0010975 161 0.016
sex differentiation GO:0007548 113 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
neuron apoptotic process GO:0051402 88 0.016
developmental process involved in reproduction GO:0003006 159 0.016
intracellular protein transport GO:0006886 79 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
forebrain development GO:0030900 98 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
regulation of neuron differentiation GO:0045664 208 0.015
Rat
single organism intracellular transport GO:1902582 166 0.015
response to growth factor GO:0070848 189 0.015
behavior GO:0007610 205 0.015
cellular homeostasis GO:0019725 252 0.015
immune system process GO:0002376 204 0.015
response to mechanical stimulus GO:0009612 134 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
axonogenesis GO:0007409 71 0.015
regulation of hormone levels GO:0010817 187 0.015
response to decreased oxygen levels GO:0036293 237 0.015
organic substance catabolic process GO:1901575 316 0.015
aromatic compound catabolic process GO:0019439 168 0.015
cellular catabolic process GO:0044248 295 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
heterocycle catabolic process GO:0046700 167 0.014
cellular protein localization GO:0034613 122 0.014
developmental growth GO:0048589 100 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
response to carbohydrate GO:0009743 183 0.014
ras protein signal transduction GO:0007265 29 0.014
positive regulation of cell development GO:0010720 176 0.014
Rat
cellular response to peptide GO:1901653 133 0.014
secretion by cell GO:0032940 248 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
single organism biosynthetic process GO:0044711 342 0.014
cellular component assembly GO:0022607 360 0.014
cellular response to lipid GO:0071396 201 0.014
Rat
nucleotide metabolic process GO:0009117 279 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
positive regulation of protein modification process GO:0031401 142 0.014
regulation of system process GO:0044057 208 0.014
positive regulation of neurogenesis GO:0050769 165 0.013
Rat
telencephalon development GO:0021537 62 0.013
formation of primary germ layer GO:0001704 1 0.013
cellular component morphogenesis GO:0032989 155 0.013
regulation of secretion GO:0051046 224 0.013
positive regulation of nervous system development GO:0051962 178 0.013
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
Rat
vesicle mediated transport GO:0016192 181 0.013
regulation of kinase activity GO:0043549 117 0.013
regulation of protein kinase activity GO:0045859 105 0.013
sexual reproduction GO:0019953 148 0.013
circadian rhythm GO:0007623 88 0.013
response to monosaccharide GO:0034284 159 0.013
regulation of body fluid levels GO:0050878 90 0.013
organelle localization GO:0051640 55 0.013
adult locomotory behavior GO:0008344 4 0.013
regulation of transferase activity GO:0051338 123 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
Rat
positive regulation of programmed cell death GO:0043068 157 0.013
immune system development GO:0002520 41 0.013
cellular response to external stimulus GO:0071496 118 0.013
transmembrane transport GO:0055085 412 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
Rat
response to oxygen levels GO:0070482 265 0.012
regulation of neuron death GO:1901214 115 0.012
ion homeostasis GO:0050801 212 0.012
histone h3 acetylation GO:0043966 2 0.012
gamete generation GO:0007276 124 0.012
single organism organelle organization GO:1902589 180 0.012
male gamete generation GO:0048232 99 0.012
cellular macromolecule localization GO:0070727 122 0.012
purine containing compound metabolic process GO:0072521 253 0.012
locomotion GO:0040011 237 0.012
regulation of response to wounding GO:1903034 69 0.012
protein heterooligomerization GO:0051291 89 0.012
homeostatic process GO:0042592 331 0.012
salivary gland morphogenesis GO:0007435 1 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
gastrulation GO:0007369 2 0.012
hormone secretion GO:0046879 115 0.012
spermatogenesis GO:0007283 99 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.012
cytoplasmic transport GO:0016482 115 0.012
response to hydrogen peroxide GO:0042542 89 0.012
positive regulation of cell death GO:0010942 184 0.012
cation transport GO:0006812 382 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
nitrogen compound transport GO:0071705 229 0.012
organophosphate catabolic process GO:0046434 148 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
response to ketone GO:1901654 182 0.011
Rat
muscle system process GO:0003012 115 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
muscle structure development GO:0061061 87 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
cell migration GO:0016477 197 0.011
ion transmembrane transport GO:0034220 365 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
tissue development GO:0009888 252 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
metal ion homeostasis GO:0055065 186 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
catabolic process GO:0009056 351 0.011
cell type specific apoptotic process GO:0097285 134 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
negative regulation of developmental process GO:0051093 125 0.011
cell cycle GO:0007049 101 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
regulation of cell cycle GO:0051726 73 0.011
reproductive structure development GO:0048608 128 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
axon guidance GO:0007411 24 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
response to temperature stimulus GO:0009266 94 0.011
cognition GO:0050890 92 0.011
response to estrogen GO:0043627 232 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
regulation of immune system process GO:0002682 123 0.011
vesicle localization GO:0051648 33 0.011
calcium ion transport GO:0006816 131 0.011
hormone transport GO:0009914 121 0.011
salivary gland development GO:0007431 3 0.011
establishment of organelle localization GO:0051656 37 0.011
anion transport GO:0006820 178 0.011
calcium ion homeostasis GO:0055074 162 0.010
regulation of synaptic transmission GO:0050804 141 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
Rat
nucleotide catabolic process GO:0009166 139 0.010
proteolysis GO:0006508 175 0.010
peptide secretion GO:0002790 86 0.010
response to insulin GO:0032868 133 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
response to hypoxia GO:0001666 231 0.010
erythrocyte differentiation GO:0030218 1 0.010
embryonic axis specification GO:0000578 1 0.010
spindle organization GO:0007051 2 0.010
cell cycle checkpoint GO:0000075 2 0.010
olfactory behavior GO:0042048 2 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
nucleoside catabolic process GO:0009164 126 0.010
negative regulation of cell development GO:0010721 82 0.010
cell cycle process GO:0022402 57 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
cell adhesion GO:0007155 110 0.010
liver development GO:0001889 90 0.010
negative regulation of cell communication GO:0010648 158 0.010

Dnmt3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
central nervous system disease DOID:331 0 0.017
musculoskeletal system disease DOID:17 0 0.016