Rattus norvegicus

56 known processes

Serpina3k

serine (or cysteine) peptidase inhibitor, clade A, member 3K

(Aliases: SPI2,Spin2b,CPi-21,Spin2)

Serpina3k biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of serine type peptidase activity GO:1902572 1 0.998
Rat
negative regulation of serine type endopeptidase activity GO:1900004 1 0.997
Rat
response to vitamin b6 GO:0034516 1 0.992
Rat
response to methanol GO:0033986 1 0.953
Rat
regulation of serine type peptidase activity GO:1902571 1 0.946
Rat
regulation of serine type endopeptidase activity GO:1900003 1 0.847
Rat
response to peptide GO:1901652 292 0.845
Mouse Rat
extracellular matrix constituent secretion GO:0070278 4 0.829
Rat
artery smooth muscle contraction GO:0014824 4 0.794
Rat
multi multicellular organism process GO:0044706 138 0.773
Rat
response to organophosphorus GO:0046683 102 0.743
Rat
response to peptide hormone GO:0043434 278 0.739
Mouse Rat
response to chromate GO:0046687 3 0.706
Rat
brain renin angiotensin system GO:0002035 3 0.697
Rat
response to purine containing compound GO:0014074 126 0.686
Rat
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.670
Rat
stress activated protein kinase signaling cascade GO:0031098 37 0.669
Rat
cellular response to organonitrogen compound GO:0071417 197 0.647
Rat
response to extracellular stimulus GO:0009991 380 0.617
Rat
angiotensin mediated drinking behavior GO:0003051 2 0.612
Rat
response to glucocorticoid GO:0051384 223 0.611
Rat
positive regulation of extracellular matrix organization GO:1903055 4 0.595
Rat
regulation of extracellular matrix constituent secretion GO:0003330 2 0.586
Rat
response to estrogen GO:0043627 232 0.581
Rat
response to triglyceride GO:0034014 3 0.567
Rat
naphthalene metabolic process GO:0018931 2 0.551
cellular response to nitrogen compound GO:1901699 210 0.545
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.542
Rat
response to acid chemical GO:0001101 222 0.525
Rat
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.507
Rat
defense response GO:0006952 194 0.497
Rat
response to cesium ion GO:0010164 2 0.489
regulation of hydrolase activity GO:0051336 143 0.465
Rat
response to corticosteroid GO:0031960 235 0.439
Rat
response to camp GO:0051591 91 0.430
Rat
response to nutrient GO:0007584 248 0.417
Rat
regulation of molecular function GO:0065009 398 0.413
Rat
cellular response to interleukin 6 GO:0071354 9 0.411
Rat
regulation of system process GO:0044057 208 0.385
Rat
renin angiotensin regulation of aldosterone production GO:0002018 3 0.380
Rat
synaptic transmission GO:0007268 235 0.371
Rat
regulation of secretion GO:0051046 224 0.365
Rat
response to inorganic substance GO:0010035 377 0.365
Rat
regulation of cellular component organization GO:0051128 368 0.362
Rat
angiogenesis GO:0001525 53 0.352
response to oxygen levels GO:0070482 265 0.347
Rat
response to mineralocorticoid GO:0051385 49 0.344
Rat
cellular response to hormone stimulus GO:0032870 247 0.344
Rat
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.335
Rat
cellular response to organic cyclic compound GO:0071407 202 0.320
Rat
trichloroethylene metabolic process GO:0018979 1 0.319
positive regulation of catalytic activity GO:0043085 184 0.316
Rat
regulation of angiogenesis GO:0045765 39 0.309
response to estradiol GO:0032355 164 0.302
Rat
amine transport GO:0015837 57 0.302
Rat
cellular response to peptide GO:1901653 133 0.302
monoamine transport GO:0015844 43 0.299
Rat
liver development GO:0001889 90 0.299
cellular response to lipid GO:0071396 201 0.298
Rat
circulatory system process GO:0003013 183 0.294
Rat
cellular response to oxygen containing compound GO:1901701 386 0.287
Rat
response to decreased oxygen levels GO:0036293 237 0.284
Rat
negative regulation of blood vessel morphogenesis GO:2000181 10 0.282
naphthalene containing compound metabolic process GO:0090420 2 0.277
response to metal ion GO:0010038 253 0.270
Rat
response to transition metal nanoparticle GO:1990267 122 0.270
Rat
reproductive process GO:0022414 372 0.269
Rat
regulation of catalytic activity GO:0050790 304 0.268
Rat
cellular protein localization GO:0034613 122 0.268
Rat
organic hydroxy compound transport GO:0015850 77 0.259
Rat
negative regulation of vasculature development GO:1901343 11 0.254
cellular response to interleukin 1 GO:0071347 37 0.250
Rat
divalent inorganic cation transport GO:0072511 134 0.235
Rat
response to insulin GO:0032868 133 0.232
tonic smooth muscle contraction GO:0014820 4 0.231
Rat
homeostatic process GO:0042592 331 0.227
Rat
oxidation reduction process GO:0055114 304 0.224
negative regulation of cellular metabolic process GO:0031324 281 0.223
Rat
response to lead ion GO:0010288 33 0.218
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.214
regulation of ion transport GO:0043269 245 0.214
Rat
organic substance catabolic process GO:1901575 316 0.213
positive regulation of transport GO:0051050 245 0.213
Rat
oxoacid metabolic process GO:0043436 290 0.213
cation homeostasis GO:0055080 195 0.208
Rat
organic acid metabolic process GO:0006082 292 0.207
renal sodium excretion GO:0035812 20 0.204
Rat
response to corticosterone GO:0051412 40 0.199
Rat
divalent metal ion transport GO:0070838 132 0.199
Rat
response to ketone GO:1901654 182 0.199
Rat
response to carbohydrate GO:0009743 183 0.199
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.192
Rat
positive regulation of hydrolase activity GO:0051345 86 0.191
Rat
icosanoid metabolic process GO:0006690 38 0.190
macromolecule localization GO:0033036 252 0.185
Rat
response to nutrient levels GO:0031667 370 0.180
Rat
positive regulation of secretion GO:0051047 140 0.180
Rat
regulation of synaptic plasticity GO:0048167 70 0.176
Rat
renal system process GO:0003014 40 0.175
Rat
cellular catabolic process GO:0044248 295 0.169
g protein coupled receptor signaling pathway GO:0007186 242 0.166
Rat
calcium ion transport GO:0006816 131 0.166
Rat
cellular chemical homeostasis GO:0055082 247 0.166
Rat
response to alkaloid GO:0043279 132 0.163
cell cell signaling GO:0007267 335 0.160
Rat
muscle contraction GO:0006936 88 0.159
Rat
cellular macromolecule localization GO:0070727 122 0.156
Rat
response to ethanol GO:0045471 162 0.156
catecholamine secretion GO:0050432 33 0.155
Rat
ion transmembrane transport GO:0034220 365 0.155
cellular response to endogenous stimulus GO:0071495 377 0.151
Rat
response to lipopolysaccharide GO:0032496 191 0.151
Rat
acylglycerol metabolic process GO:0006639 21 0.150
secretion GO:0046903 307 0.147
Rat
growth GO:0040007 165 0.142
Rat
protein transport GO:0015031 132 0.138
Rat
cellular response to cytokine stimulus GO:0071345 127 0.137
Rat
cellular response to stress GO:0033554 269 0.137
Rat
hepaticobiliary system development GO:0061008 90 0.135
monocarboxylic acid metabolic process GO:0032787 152 0.134
cellular response to insulin stimulus GO:0032869 81 0.132
endothelial cell proliferation GO:0001935 20 0.130
behavior GO:0007610 205 0.129
Rat
regulation of cell growth GO:0001558 85 0.125
Rat
chemical homeostasis GO:0048878 292 0.125
Rat
positive regulation of fibroblast proliferation GO:0048146 15 0.125
Rat
organ regeneration GO:0031100 101 0.125
smooth muscle contraction GO:0006939 37 0.124
Rat
c21 steroid hormone biosynthetic process GO:0006700 10 0.121
regulation of amine transport GO:0051952 54 0.120
Rat
response to hexose GO:0009746 144 0.118
cellular response to external stimulus GO:0071496 118 0.118
Rat
long chain fatty acid metabolic process GO:0001676 32 0.118
vasculature development GO:0001944 70 0.117
regulation of blood pressure GO:0008217 83 0.117
Rat
response to cytokine GO:0034097 215 0.115
Mouse Rat
cellular homeostasis GO:0019725 252 0.114
Rat
blood vessel morphogenesis GO:0048514 58 0.114
fatty acid derivative metabolic process GO:1901568 38 0.114
single organism catabolic process GO:0044712 283 0.113
cellular response to interferon gamma GO:0071346 14 0.110
Rat
neutral lipid metabolic process GO:0006638 21 0.109
response to starvation GO:0042594 59 0.108
catabolic process GO:0009056 351 0.108
catecholamine transport GO:0051937 37 0.108
Rat
positive regulation of secretion by cell GO:1903532 128 0.106
Rat
excretion GO:0007588 24 0.105
Rat
cell growth GO:0016049 104 0.105
Rat
metal ion transport GO:0030001 289 0.105
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.104
Rat
macromolecular complex subunit organization GO:0043933 339 0.103
fatty acid metabolic process GO:0006631 99 0.101
vasoconstriction GO:0042310 54 0.100
Rat
drug metabolic process GO:0017144 11 0.099
carbohydrate metabolic process GO:0005975 130 0.098
protein localization GO:0008104 191 0.097
Rat
intracellular protein transport GO:0006886 79 0.096
Rat
organic acid biosynthetic process GO:0016053 83 0.095
protein complex biogenesis GO:0070271 263 0.094
cardiac cell development GO:0055006 16 0.093
Rat
testosterone biosynthetic process GO:0061370 5 0.093
positive regulation of molecular function GO:0044093 230 0.093
Rat
intracellular signal transduction GO:0035556 314 0.092
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.092
protein complex assembly GO:0006461 263 0.092
regulation of muscle system process GO:0090257 79 0.091
Rat
glycerolipid metabolic process GO:0046486 67 0.091
carboxylic acid metabolic process GO:0019752 289 0.091
metal ion homeostasis GO:0055065 186 0.091
Rat
positive regulation of blood circulation GO:1903524 65 0.091
Rat
organonitrogen compound catabolic process GO:1901565 179 0.090
secretion by cell GO:0032940 248 0.090
Rat
female pregnancy GO:0007565 122 0.090
Rat
blood circulation GO:0008015 183 0.089
Rat
cardiac muscle cell development GO:0055013 16 0.089
Rat
establishment of protein localization GO:0045184 141 0.088
Rat
exogenous drug catabolic process GO:0042738 1 0.088
response to herbicide GO:0009635 16 0.088
negative regulation of peptidase activity GO:0010466 38 0.088
Rat
organic hydroxy compound biosynthetic process GO:1901617 51 0.084
protein complex subunit organization GO:0071822 302 0.084
cellular response to camp GO:0071320 26 0.084
Rat
negative regulation of protein metabolic process GO:0051248 114 0.083
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.083
feeding behavior GO:0007631 53 0.082
Rat
response to mechanical stimulus GO:0009612 134 0.082
Rat
regulation of synaptic transmission GO:0050804 141 0.082
Rat
cellular metal ion homeostasis GO:0006875 172 0.081
Rat
regeneration GO:0031099 163 0.080
cellular cation homeostasis GO:0030003 180 0.080
Rat
epoxygenase p450 pathway GO:0019373 1 0.080
cellular amine metabolic process GO:0044106 38 0.078
organophosphate catabolic process GO:0046434 148 0.078
response to glucose GO:0009749 136 0.077
response to food GO:0032094 27 0.077
regulation of excretion GO:0044062 21 0.076
Rat
regulation of cellular localization GO:0060341 263 0.076
Rat
regulation of multicellular organismal development GO:2000026 376 0.075
response to interleukin 1 GO:0070555 55 0.075
Rat
cellular ketone metabolic process GO:0042180 51 0.073
aging GO:0007568 241 0.073
Rat
response to monosaccharide GO:0034284 159 0.073
gland development GO:0048732 155 0.072
response to activity GO:0014823 73 0.069
Rat
cellular sodium ion homeostasis GO:0006883 4 0.066
Rat
lipid biosynthetic process GO:0008610 128 0.065
regulation of protein processing GO:0070613 50 0.065
Rat
ion homeostasis GO:0050801 212 0.064
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.063
halogenated hydrocarbon metabolic process GO:0042197 4 0.062
single organism nuclear import GO:1902593 35 0.062
Rat
vascular process in circulatory system GO:0003018 96 0.062
Rat
small molecule biosynthetic process GO:0044283 124 0.061
negative regulation of macromolecule metabolic process GO:0010605 260 0.060
Rat
regulation of hormone levels GO:0010817 187 0.059
cation transport GO:0006812 382 0.059
Rat
single organism biosynthetic process GO:0044711 342 0.059
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.058
response to hypoxia GO:0001666 231 0.058
Rat
isoprenoid metabolic process GO:0006720 45 0.058
nitrogen compound transport GO:0071705 229 0.057
Rat
regulation of norepinephrine secretion GO:0014061 15 0.057
Rat
cellular lipid metabolic process GO:0044255 208 0.057
protein oligomerization GO:0051259 191 0.057
monocarboxylic acid transport GO:0015718 52 0.056
regulation of catecholamine secretion GO:0050433 32 0.056
Rat
carboxylic acid catabolic process GO:0046395 49 0.055
mapk cascade GO:0000165 140 0.055
Rat
estrogen biosynthetic process GO:0006703 6 0.055
reactive nitrogen species metabolic process GO:2001057 1 0.054
response to vitamin GO:0033273 131 0.054
Rat
amine metabolic process GO:0009308 38 0.054
steroid biosynthetic process GO:0006694 48 0.054
programmed cell death GO:0012501 392 0.053
cellular amino acid metabolic process GO:0006520 107 0.052
cellular lipid catabolic process GO:0044242 37 0.052
multi organism reproductive process GO:0044703 262 0.052
Rat
response to sulfur dioxide GO:0010477 3 0.052
response to reactive oxygen species GO:0000302 120 0.051
negative regulation of phosphorus metabolic process GO:0010563 80 0.051
alkaloid metabolic process GO:0009820 3 0.050
sensory perception GO:0007600 101 0.050
proteolysis GO:0006508 175 0.050
Rat
protein targeting GO:0006605 61 0.049
Rat
regulation of apoptotic process GO:0042981 335 0.049
regulation of calcium ion transport GO:0051924 77 0.049
Rat
cardiovascular system development GO:0072358 134 0.048
regulation of renal sodium excretion GO:0035813 20 0.048
Rat
negative regulation of response to stimulus GO:0048585 155 0.048
negative regulation of angiogenesis GO:0016525 10 0.048
macromolecular complex assembly GO:0065003 273 0.047
regulation of cellular amino acid metabolic process GO:0006521 2 0.047
positive regulation of apoptotic process GO:0043065 154 0.047
negative regulation of metabolic process GO:0009892 331 0.047
Rat
muscle system process GO:0003012 115 0.046
Rat
regulation of blood circulation GO:1903522 110 0.046
Rat
regulation of blood vessel size GO:0050880 89 0.046
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.046
Rat
protein maturation GO:0051604 68 0.046
Rat
negative regulation of molecular function GO:0044092 133 0.046
Rat
norepinephrine secretion GO:0048243 16 0.046
Rat
regulation of programmed cell death GO:0043067 341 0.045
cellular response to abiotic stimulus GO:0071214 85 0.045
Rat
regulation of secretion by cell GO:1903530 208 0.045
Rat
cellular response to corticosteroid stimulus GO:0071384 69 0.045
Rat
protein processing GO:0016485 68 0.045
Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.045
Rat
heart development GO:0007507 72 0.044
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.044
Rat
regulation of growth GO:0040008 105 0.043
Rat
reactive oxygen species metabolic process GO:0072593 37 0.043
Rat
unsaturated fatty acid metabolic process GO:0033559 39 0.043
blood vessel development GO:0001568 69 0.043
establishment of protein localization to organelle GO:0072594 44 0.043
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.043
organonitrogen compound biosynthetic process GO:1901566 167 0.042
circulatory system development GO:0072359 134 0.042
lipid metabolic process GO:0006629 283 0.042
chlorinated hydrocarbon metabolic process GO:0042196 4 0.041
rhythmic process GO:0048511 156 0.041
organophosphate metabolic process GO:0019637 370 0.040
regulation of neurological system process GO:0031644 43 0.040
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.040
Rat
diterpenoid metabolic process GO:0016101 33 0.040
response to toxic substance GO:0009636 133 0.040
regulation of tube size GO:0035150 89 0.039
Rat
endocrine process GO:0050886 32 0.039
Rat
negative regulation of epithelial cell proliferation GO:0050680 16 0.039
steroid metabolic process GO:0008202 73 0.039
purine ribonucleoside metabolic process GO:0046128 168 0.039
drug catabolic process GO:0042737 1 0.039
glycosyl compound metabolic process GO:1901657 182 0.038
glycogen metabolic process GO:0005977 23 0.038
cellular carbohydrate metabolic process GO:0044262 72 0.038
uterine smooth muscle contraction GO:0070471 10 0.037
Rat
alpha amino acid metabolic process GO:1901605 71 0.037
aromatic amino acid family catabolic process GO:0009074 7 0.037
regulation of hemostasis GO:1900046 9 0.037
regulation of lipid biosynthetic process GO:0046890 38 0.037
negative regulation of catalytic activity GO:0043086 103 0.037
Rat
energy derivation by oxidation of organic compounds GO:0015980 46 0.036
regulation of neuronal synaptic plasticity GO:0048168 31 0.036
Rat
protein localization to organelle GO:0033365 57 0.036
Rat
anion transport GO:0006820 178 0.036
lipid transport GO:0006869 61 0.036
protein phosphorylation GO:0006468 345 0.035
small molecule catabolic process GO:0044282 59 0.035
triglyceride metabolic process GO:0006641 21 0.035
reactive oxygen species biosynthetic process GO:1903409 8 0.035
smooth muscle cell proliferation GO:0048659 77 0.035
Rat
energy reserve metabolic process GO:0006112 25 0.035
phenol containing compound metabolic process GO:0018958 30 0.034
response to calcium ion GO:0051592 59 0.034
regulation of metal ion transport GO:0010959 118 0.034
Rat
regulation of anatomical structure size GO:0090066 135 0.034
Rat
response to radiation GO:0009314 137 0.034
plasminogen activation GO:0031639 2 0.034
single organism behavior GO:0044708 130 0.034
urinary tract smooth muscle contraction GO:0014848 4 0.034
positive regulation of long term synaptic potentiation GO:1900273 4 0.033
negative regulation of developmental process GO:0051093 125 0.033
nucleoside metabolic process GO:0009116 179 0.033
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 13 0.033
Rat
cellular component biogenesis GO:0044085 368 0.032
response to temperature stimulus GO:0009266 94 0.032
regulation of systemic arterial blood pressure GO:0003073 30 0.032
Rat
insecticide metabolic process GO:0017143 4 0.031
linoleic acid metabolic process GO:0043651 4 0.031
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.031
negative regulation of gene expression GO:0010629 199 0.031
Rat
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.031
positive regulation of phospholipase c activity GO:0010863 8 0.031
Rat
regulation of protein metabolic process GO:0051246 289 0.031
Rat
negative regulation of protein maturation GO:1903318 47 0.031
Rat
cardiocyte differentiation GO:0035051 22 0.031
Rat
purine ribonucleoside catabolic process GO:0046130 124 0.031
regulation of endothelial cell proliferation GO:0001936 18 0.030
response to ammonium ion GO:0060359 71 0.030
small gtpase mediated signal transduction GO:0007264 36 0.030
ras protein signal transduction GO:0007265 29 0.030
aromatic compound catabolic process GO:0019439 168 0.030
sodium ion homeostasis GO:0055078 23 0.030
Rat
purine nucleoside metabolic process GO:0042278 169 0.030
cellular response to mechanical stimulus GO:0071260 48 0.029
Rat
regulation of cell projection organization GO:0031344 175 0.029
protein targeting to nucleus GO:0044744 35 0.029
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.029
response to cocaine GO:0042220 39 0.029
monosaccharide metabolic process GO:0005996 61 0.029
response to cold GO:0009409 29 0.029
generation of precursor metabolites and energy GO:0006091 62 0.029
organic cyclic compound catabolic process GO:1901361 175 0.028
regulation of cell proliferation GO:0042127 359 0.028
heterocycle catabolic process GO:0046700 167 0.028
nuclear transport GO:0051169 49 0.028
Rat
coenzyme metabolic process GO:0006732 86 0.028
cellular response to glucocorticoid stimulus GO:0071385 68 0.028
Rat
carbohydrate catabolic process GO:0016052 40 0.028
response to other organism GO:0051707 220 0.028
Rat
transmission of nerve impulse GO:0019226 42 0.028
Rat
androgen biosynthetic process GO:0006702 10 0.027
regulation of vasodilation GO:0042312 36 0.027
Rat
regulation of homeostatic process GO:0032844 101 0.027
Rat
cellular response to metal ion GO:0071248 55 0.027
peptide secretion GO:0002790 86 0.027
lipid localization GO:0010876 62 0.027
regulation of long term neuronal synaptic plasticity GO:0048169 15 0.026
Rat
response to molecule of bacterial origin GO:0002237 194 0.026
Rat
telencephalon development GO:0021537 62 0.026
vasodilation GO:0042311 44 0.026
Rat
regulation of endothelial cell apoptotic process GO:2000351 3 0.026
positive regulation of neuron projection development GO:0010976 99 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
hexose metabolic process GO:0019318 58 0.026
response to oxidative stress GO:0006979 186 0.026
cellular component assembly GO:0022607 360 0.026
protein import into nucleus GO:0006606 35 0.026
Rat
positive regulation of programmed cell death GO:0043068 157 0.026
regulation of vasculature development GO:1901342 44 0.026
negative regulation of systemic arterial blood pressure GO:0003085 4 0.025
positive regulation of vasodilation GO:0045909 29 0.025
Rat
neurological system process GO:0050877 219 0.025
Rat
cytokine production GO:0001816 61 0.025
Rat
response to acetate GO:0010034 3 0.025
locomotion GO:0040011 237 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.024
cardiac muscle tissue morphogenesis GO:0055008 1 0.024
positive regulation of cell projection organization GO:0031346 111 0.024
single organism carbohydrate metabolic process GO:0044723 118 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
positive regulation of ion transport GO:0043270 94 0.024
response to biotic stimulus GO:0009607 226 0.024
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
potassium ion transport GO:0006813 97 0.024
vesicle mediated transport GO:0016192 181 0.023
regulation of nitric oxide biosynthetic process GO:0045428 20 0.023
Rat
cellular polysaccharide metabolic process GO:0044264 23 0.023
regulation of peptidase activity GO:0052547 55 0.023
Rat
positive regulation of cellular component organization GO:0051130 200 0.023
Rat
regulation of nervous system development GO:0051960 264 0.023
cation transmembrane transport GO:0098655 263 0.023
regulation of phospholipase activity GO:0010517 12 0.023
Rat
regulation of phosphorylation GO:0042325 248 0.023
response to testosterone GO:0033574 55 0.023
apoptotic process GO:0006915 381 0.023
positive regulation of blood pressure GO:0045777 31 0.023
Rat
positive regulation of homeostatic process GO:0032846 49 0.023
Rat
response to hyperoxia GO:0055093 45 0.023
cellular response to gonadotropin stimulus GO:0071371 17 0.023
positive regulation of protein modification process GO:0031401 142 0.023
response to growth factor GO:0070848 189 0.022
response to amphetamine GO:0001975 25 0.022
ribonucleotide catabolic process GO:0009261 136 0.022
isoquinoline alkaloid metabolic process GO:0033076 2 0.022
glucose homeostasis GO:0042593 75 0.022
lipid catabolic process GO:0016042 46 0.022
multicellular organism growth GO:0035264 1 0.022
retinoid metabolic process GO:0001523 24 0.022
androgen metabolic process GO:0008209 14 0.022
heart morphogenesis GO:0003007 3 0.022
cellular response to alcohol GO:0097306 87 0.022
single organism intracellular transport GO:1902582 166 0.022
Rat
transmembrane transport GO:0055085 412 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
positive regulation of biosynthetic process GO:0009891 319 0.021
Rat
cardiac muscle tissue development GO:0048738 26 0.021
Rat
muscle tissue development GO:0060537 58 0.021
Rat
cellular glucan metabolic process GO:0006073 23 0.021
nucleoside phosphate catabolic process GO:1901292 140 0.021
neuron projection development GO:0031175 273 0.021
innate immune response GO:0045087 35 0.021
Rat
regulation of nucleotide catabolic process GO:0030811 65 0.021
muscle structure development GO:0061061 87 0.021
Rat
negative regulation of cell communication GO:0010648 158 0.021
monocarboxylic acid biosynthetic process GO:0072330 48 0.020
response to amine GO:0014075 46 0.020
positive regulation of cell communication GO:0010647 271 0.020
positive regulation of developmental process GO:0051094 283 0.020
regulation of response to stress GO:0080134 126 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
positive regulation of gene expression GO:0010628 244 0.020
acid secretion GO:0046717 48 0.020
regulation of lipid metabolic process GO:0019216 68 0.020
response to nicotine GO:0035094 51 0.019
negative regulation of growth GO:0045926 37 0.019
Rat
c21 steroid hormone metabolic process GO:0008207 14 0.019
carbohydrate homeostasis GO:0033500 75 0.019
multicellular organismal signaling GO:0035637 44 0.019
Rat
positive regulation of protein metabolic process GO:0051247 178 0.019
gonad development GO:0008406 104 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
choline transport GO:0015871 4 0.018
response to fatty acid GO:0070542 65 0.018
Rat
developmental growth GO:0048589 100 0.018
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
chylomicron remodeling GO:0034371 1 0.018
gamma aminobutyric acid transport GO:0015812 8 0.018
monovalent inorganic cation homeostasis GO:0055067 36 0.018
Rat
cartilage condensation GO:0001502 2 0.018
regulation of neurotransmitter levels GO:0001505 42 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
Rat
n methyl d aspartate receptor clustering GO:0097114 2 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.018
nucleoside triphosphate metabolic process GO:0009141 144 0.018
carboxylic acid transport GO:0046942 115 0.017
purine nucleoside monophosphate catabolic process GO:0009128 55 0.017
central nervous system development GO:0007417 311 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.017
negative regulation of endothelial cell proliferation GO:0001937 5 0.017
behavioral response to cocaine GO:0048148 6 0.017
regulation of reactive oxygen species metabolic process GO:2000377 26 0.017
Rat
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
regulation of neurotransmitter uptake GO:0051580 1 0.017
drinking behavior GO:0042756 11 0.017
Rat
protein secretion GO:0009306 34 0.017
Rat
insulin receptor signaling pathway GO:0008286 24 0.017
arginine metabolic process GO:0006525 6 0.017
negative regulation of hydrolase activity GO:0051346 52 0.017
Rat
ribonucleoside monophosphate metabolic process GO:0009161 88 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
neuron neuron synaptic transmission GO:0007270 60 0.017
negative regulation of cell growth GO:0030308 33 0.016
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
regulation of protein maturation GO:1903317 50 0.016
Rat
muscle tissue morphogenesis GO:0060415 1 0.016
regulation of ion homeostasis GO:2000021 63 0.016
Rat
neuron differentiation GO:0030182 368 0.016
response to wounding GO:0009611 254 0.016
response to increased oxygen levels GO:0036296 45 0.016
nucleic acid templated transcription GO:0097659 379 0.016

Serpina3k disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
vascular disease DOID:178 0 0.017
cardiovascular system disease DOID:1287 0 0.017