Rattus norvegicus

5 known processes

Tmlhe

trimethyllysine hydroxylase, epsilon

(Aliases: MGC94841,Tmlh)

Tmlhe biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.126
organic acid metabolic process GO:0006082 292 0.097
intracellular signal transduction GO:0035556 314 0.094
carboxylic acid metabolic process GO:0019752 289 0.087
lipid metabolic process GO:0006629 283 0.069
aging GO:0007568 241 0.067
single organism biosynthetic process GO:0044711 342 0.060
rna metabolic process GO:0016070 406 0.059
organic substance catabolic process GO:1901575 316 0.056
regulation of signal transduction GO:0009966 318 0.054
organophosphate metabolic process GO:0019637 370 0.051
small molecule catabolic process GO:0044282 59 0.051
cellular amino acid metabolic process GO:0006520 107 0.050
catabolic process GO:0009056 351 0.050
nucleic acid templated transcription GO:0097659 379 0.049
regulation of molecular function GO:0065009 398 0.048
regulation of transcription dna templated GO:0006355 374 0.048
cellular response to endogenous stimulus GO:0071495 377 0.047
regulation of phosphate metabolic process GO:0019220 349 0.047
cellular lipid metabolic process GO:0044255 208 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.044
apoptotic process GO:0006915 381 0.044
cellular catabolic process GO:0044248 295 0.042
homeostatic process GO:0042592 331 0.041
sulfur compound metabolic process GO:0006790 70 0.040
cellular response to stress GO:0033554 269 0.039
regulation of intracellular signal transduction GO:1902531 218 0.039
nucleobase containing small molecule metabolic process GO:0055086 316 0.039
cellular component biogenesis GO:0044085 368 0.038
regulation of phosphorus metabolic process GO:0051174 349 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.037
regulation of rna metabolic process GO:0051252 391 0.037
response to oxygen levels GO:0070482 265 0.036
oxidation reduction process GO:0055114 304 0.036
transcription dna templated GO:0006351 377 0.036
regulation of nucleic acid templated transcription GO:1903506 380 0.036
response to inorganic substance GO:0010035 377 0.036
cellular response to oxygen containing compound GO:1901701 386 0.036
protein phosphorylation GO:0006468 345 0.036
positive regulation of molecular function GO:0044093 230 0.035
programmed cell death GO:0012501 392 0.035
rna biosynthetic process GO:0032774 380 0.035
macromolecular complex assembly GO:0065003 273 0.033
response to peptide hormone GO:0043434 278 0.033
alpha amino acid metabolic process GO:1901605 71 0.033
single organism catabolic process GO:0044712 283 0.032
response to estrogen GO:0043627 232 0.032
positive regulation of phosphate metabolic process GO:0045937 262 0.032
response to nutrient levels GO:0031667 370 0.032
coenzyme metabolic process GO:0006732 86 0.032
regulation of secretion by cell GO:1903530 208 0.032
positive regulation of catalytic activity GO:0043085 184 0.032
response to decreased oxygen levels GO:0036293 237 0.031
endocytosis GO:0006897 84 0.031
regulation of cell differentiation GO:0045595 320 0.031
chemical homeostasis GO:0048878 292 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.030
vesicle mediated transport GO:0016192 181 0.030
secretion GO:0046903 307 0.030
cellular component assembly GO:0022607 360 0.030
positive regulation of cell communication GO:0010647 271 0.030
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
cellular ketone metabolic process GO:0042180 51 0.028
single organism reproductive process GO:0044702 297 0.027
regulation of catalytic activity GO:0050790 304 0.027
response to metal ion GO:0010038 253 0.027
secretion by cell GO:0032940 248 0.027
positive regulation of phosphorylation GO:0042327 177 0.027
purine containing compound metabolic process GO:0072521 253 0.027
regulation of neuron death GO:1901214 115 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
response to extracellular stimulus GO:0009991 380 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
organophosphate biosynthetic process GO:0090407 143 0.026
regulation of phosphorylation GO:0042325 248 0.026
regulation of multicellular organismal development GO:2000026 376 0.026
amine metabolic process GO:0009308 38 0.025
cellular homeostasis GO:0019725 252 0.025
negative regulation of cell death GO:0060548 229 0.025
positive regulation of protein metabolic process GO:0051247 178 0.025
protein complex biogenesis GO:0070271 263 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
reproductive process GO:0022414 372 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
regulation of cellular component organization GO:0051128 368 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
regulation of programmed cell death GO:0043067 341 0.024
cellular amine metabolic process GO:0044106 38 0.024
central nervous system development GO:0007417 311 0.024
regulation of protein phosphorylation GO:0001932 183 0.024
protein oligomerization GO:0051259 191 0.024
regulation of secretion GO:0051046 224 0.024
positive regulation of developmental process GO:0051094 283 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
multicellular organism reproduction GO:0032504 233 0.023
ion homeostasis GO:0050801 212 0.023
neuron differentiation GO:0030182 368 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
tissue development GO:0009888 252 0.023
response to lipopolysaccharide GO:0032496 191 0.023
response to growth factor GO:0070848 189 0.023
response to radiation GO:0009314 137 0.023
head development GO:0060322 247 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
protein complex assembly GO:0006461 263 0.022
brain development GO:0007420 247 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
regulation of protein modification process GO:0031399 194 0.022
carbohydrate metabolic process GO:0005975 130 0.022
cellular response to lipid GO:0071396 201 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.021
regulation of cell proliferation GO:0042127 359 0.021
negative regulation of transport GO:0051051 136 0.021
response to oxidative stress GO:0006979 186 0.020
dicarboxylic acid metabolic process GO:0043648 42 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
organic acid catabolic process GO:0016054 49 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
organelle organization GO:0006996 266 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
response to acid chemical GO:0001101 222 0.020
single organism intracellular transport GO:1902582 166 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
reproduction GO:0000003 245 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
response to ketone GO:1901654 182 0.019
positive regulation of signal transduction GO:0009967 175 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
monocarboxylic acid metabolic process GO:0032787 152 0.019
nucleoside metabolic process GO:0009116 179 0.019
negative regulation of cell communication GO:0010648 158 0.019
regulation of protein metabolic process GO:0051246 289 0.019
behavior GO:0007610 205 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
axis specification GO:0009798 4 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
cell cell signaling GO:0007267 335 0.018
response to ethanol GO:0045471 162 0.018
ion transmembrane transport GO:0034220 365 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
retinal metabolic process GO:0042574 3 0.018
positive regulation of signaling GO:0023056 270 0.018
regulation of kinase activity GO:0043549 117 0.018
neuron development GO:0048666 286 0.018
blood circulation GO:0008015 183 0.018
cell projection organization GO:0030030 302 0.018
positive regulation of protein modification process GO:0031401 142 0.018
cellular chemical homeostasis GO:0055082 247 0.018
response to peptide GO:1901652 292 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
negative regulation of metabolic process GO:0009892 331 0.018
regulation of apoptotic process GO:0042981 335 0.018
heart morphogenesis GO:0003007 3 0.018
fatty acid metabolic process GO:0006631 99 0.018
metal ion transport GO:0030001 289 0.018
intracellular transport GO:0046907 185 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
response to alkaloid GO:0043279 132 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
positive regulation of cell death GO:0010942 184 0.017
nitrogen compound transport GO:0071705 229 0.017
protein complex subunit organization GO:0071822 302 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
regulation of transferase activity GO:0051338 123 0.017
neuron death GO:0070997 127 0.017
mapk cascade GO:0000165 140 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
hormone transport GO:0009914 121 0.017
negative regulation of signaling GO:0023057 157 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
cation transport GO:0006812 382 0.017
positive regulation of gene expression GO:0010628 244 0.017
cellular response to oxidative stress GO:0034599 76 0.017
cellular ion homeostasis GO:0006873 184 0.017
ras protein signal transduction GO:0007265 29 0.017
regulation of hormone levels GO:0010817 187 0.016
neuron projection development GO:0031175 273 0.016
embryonic pattern specification GO:0009880 1 0.016
synaptic transmission GO:0007268 235 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
response to estradiol GO:0032355 164 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
growth GO:0040007 165 0.016
alcohol metabolic process GO:0006066 77 0.016
multi organism reproductive process GO:0044703 262 0.016
nucleotide metabolic process GO:0009117 279 0.016
rhythmic process GO:0048511 156 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.015
cation homeostasis GO:0055080 195 0.015
carboxylic acid catabolic process GO:0046395 49 0.015
transmembrane transport GO:0055085 412 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
small molecule biosynthetic process GO:0044283 124 0.015
protein localization GO:0008104 191 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
positive regulation of transport GO:0051050 245 0.015
macromolecule localization GO:0033036 252 0.015
eye morphogenesis GO:0048592 4 0.015
response to nutrient GO:0007584 248 0.015
single organism behavior GO:0044708 130 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
immune system process GO:0002376 204 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
regulation of growth GO:0040008 105 0.015
learning or memory GO:0007611 90 0.014
gonad development GO:0008406 104 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
regulation of neurogenesis GO:0050767 247 0.014
single organism organelle organization GO:1902589 180 0.014
response to hypoxia GO:0001666 231 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
multicellular organism growth GO:0035264 1 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
negative regulation of gene expression GO:0010629 199 0.014
monosaccharide metabolic process GO:0005996 61 0.014
neurological system process GO:0050877 219 0.014
regulation of mapk cascade GO:0043408 116 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
regulation of immune system process GO:0002682 123 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
regulation of catabolic process GO:0009894 113 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
reproductive structure development GO:0048608 128 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
regulation of cellular localization GO:0060341 263 0.014
circulatory system development GO:0072359 134 0.013
cardiovascular system development GO:0072358 134 0.013
glycerolipid metabolic process GO:0046486 67 0.013
proteolysis GO:0006508 175 0.013
metal ion homeostasis GO:0055065 186 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
positive regulation of cell development GO:0010720 176 0.013
cellular macromolecule localization GO:0070727 122 0.013
response to corticosteroid GO:0031960 235 0.013
anion transport GO:0006820 178 0.013
regulation of protein kinase activity GO:0045859 105 0.013
cellular protein localization GO:0034613 122 0.013
anterior posterior pattern specification GO:0009952 1 0.013
cytoplasmic transport GO:0016482 115 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
locomotion GO:0040011 237 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
dephosphorylation GO:0016311 98 0.013
signal release GO:0023061 145 0.013
cellular cation homeostasis GO:0030003 180 0.012
retina morphogenesis in camera type eye GO:0060042 1 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
response to glucocorticoid GO:0051384 223 0.012
response to insulin GO:0032868 133 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
response to glucose GO:0009749 136 0.012
organ morphogenesis GO:0009887 75 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
response to external biotic stimulus GO:0043207 221 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
fatty acid catabolic process GO:0009062 26 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
regulation of nervous system development GO:0051960 264 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
regeneration GO:0031099 163 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
protein heterooligomerization GO:0051291 89 0.012
muscle cell proliferation GO:0033002 84 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
cellular lipid catabolic process GO:0044242 37 0.012
regulation of cell development GO:0060284 263 0.012
establishment of protein localization GO:0045184 141 0.012
response to monosaccharide GO:0034284 159 0.012
positive regulation of secretion by cell GO:1903532 128 0.011
sex differentiation GO:0007548 113 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
biological adhesion GO:0022610 110 0.011
cation transmembrane transport GO:0098655 263 0.011
cell adhesion GO:0007155 110 0.011
renal system development GO:0072001 67 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
receptor mediated endocytosis GO:0006898 42 0.011
memory GO:0007613 54 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
cell morphogenesis GO:0000902 142 0.011
cellular component movement GO:0006928 248 0.011
circadian rhythm GO:0007623 88 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
cellular amino acid catabolic process GO:0009063 21 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
regulation of system process GO:0044057 208 0.011
response to hexose GO:0009746 144 0.011
neuron apoptotic process GO:0051402 88 0.011
heterocycle catabolic process GO:0046700 167 0.011
cognition GO:0050890 92 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
response to mechanical stimulus GO:0009612 134 0.011
amide transport GO:0042886 105 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
protein transport GO:0015031 132 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
developmental process involved in reproduction GO:0003006 159 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
regulation of neuron projection development GO:0010975 161 0.011
circulatory system process GO:0003013 183 0.011
response to biotic stimulus GO:0009607 226 0.011
embryonic limb morphogenesis GO:0030326 4 0.011
organophosphate catabolic process GO:0046434 148 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
response to vitamin GO:0033273 131 0.011
sexual reproduction GO:0019953 148 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
development of primary sexual characteristics GO:0045137 107 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
embryonic axis specification GO:0000578 1 0.010
regulation of synaptic transmission GO:0050804 141 0.010
regulation of transmembrane transport GO:0034762 122 0.010
development of primary female sexual characteristics GO:0046545 56 0.010
response to carbohydrate GO:0009743 183 0.010
positive regulation of catabolic process GO:0009896 78 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
single organism cellular localization GO:1902580 102 0.010
positive regulation of secretion GO:0051047 140 0.010
regulation of anatomical structure size GO:0090066 135 0.010
regulation of cell projection organization GO:0031344 175 0.010
cell type specific apoptotic process GO:0097285 134 0.010
developmental growth GO:0048589 100 0.010
adult locomotory behavior GO:0008344 4 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010

Tmlhe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.028
inherited metabolic disorder DOID:655 0 0.028
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.011