Rattus norvegicus

9 known processes

Col6a3

procollagen, type VI, alpha 3

Col6a3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell differentiation GO:0045595 320 0.078
regulation of phosphorylation GO:0042325 248 0.069
rna biosynthetic process GO:0032774 380 0.066
tissue development GO:0009888 252 0.058
regulation of nucleic acid templated transcription GO:1903506 380 0.057
reproductive process GO:0022414 372 0.056
regulation of cell proliferation GO:0042127 359 0.056
cell motility GO:0048870 202 0.055
regulation of molecular function GO:0065009 398 0.049
embryonic skeletal system development GO:0048706 3 0.048
nucleic acid templated transcription GO:0097659 379 0.048
cellular component movement GO:0006928 248 0.048
intracellular signal transduction GO:0035556 314 0.048
multi organism reproductive process GO:0044703 262 0.047
positive regulation of multicellular organismal process GO:0051240 387 0.046
transcription dna templated GO:0006351 377 0.046
multicellular organism reproduction GO:0032504 233 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
cellular amino acid metabolic process GO:0006520 107 0.043
regulation of immune system process GO:0002682 123 0.043
regulation of transcription dna templated GO:0006355 374 0.042
positive regulation of developmental process GO:0051094 283 0.042
regulation of signal transduction GO:0009966 318 0.038
embryonic skeletal system morphogenesis GO:0048704 3 0.038
locomotion GO:0040011 237 0.038
organic acid metabolic process GO:0006082 292 0.037
regulation of phosphate metabolic process GO:0019220 349 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
response to nutrient GO:0007584 248 0.036
positive regulation of cellular biosynthetic process GO:0031328 295 0.035
regulation of multicellular organismal development GO:2000026 376 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.035
regulation of rna metabolic process GO:0051252 391 0.034
reproduction GO:0000003 245 0.034
localization of cell GO:0051674 202 0.034
positive regulation of cell proliferation GO:0008284 249 0.033
response to corticosteroid GO:0031960 235 0.033
rna metabolic process GO:0016070 406 0.032
cell migration GO:0016477 197 0.031
regulation of locomotion GO:0040012 148 0.030
oxoacid metabolic process GO:0043436 290 0.030
cellular response to stress GO:0033554 269 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
positive regulation of molecular function GO:0044093 230 0.029
head development GO:0060322 247 0.029
central nervous system development GO:0007417 311 0.029
positive regulation of nervous system development GO:0051962 178 0.029
amine metabolic process GO:0009308 38 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
response to extracellular stimulus GO:0009991 380 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
regulation of programmed cell death GO:0043067 341 0.029
response to estradiol GO:0032355 164 0.029
anatomical structure morphogenesis GO:0009653 298 0.028
programmed cell death GO:0012501 392 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
response to glucocorticoid GO:0051384 223 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
protein phosphorylation GO:0006468 345 0.027
establishment of protein localization GO:0045184 141 0.027
cellular amine metabolic process GO:0044106 38 0.027
regulation of apoptotic process GO:0042981 335 0.027
regulation of nervous system development GO:0051960 264 0.027
response to estrogen GO:0043627 232 0.026
positive regulation of gene expression GO:0010628 244 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
response to vitamin GO:0033273 131 0.026
regulation of neurogenesis GO:0050767 247 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
neuron projection development GO:0031175 273 0.025
neuron differentiation GO:0030182 368 0.025
response to nutrient levels GO:0031667 370 0.025
positive regulation of cell development GO:0010720 176 0.025
multi multicellular organism process GO:0044706 138 0.025
negative regulation of metabolic process GO:0009892 331 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
brain development GO:0007420 247 0.024
positive regulation of neuron differentiation GO:0045666 126 0.024
immune system process GO:0002376 204 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
response to acid chemical GO:0001101 222 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
regulation of cell development GO:0060284 263 0.023
positive regulation of transport GO:0051050 245 0.023
nucleotide metabolic process GO:0009117 279 0.023
regulation of catalytic activity GO:0050790 304 0.023
cellular response to endogenous stimulus GO:0071495 377 0.022
regulation of protein modification process GO:0031399 194 0.022
chemical homeostasis GO:0048878 292 0.022
single organism intracellular transport GO:1902582 166 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
reactive oxygen species metabolic process GO:0072593 37 0.022
regulation of protein phosphorylation GO:0001932 183 0.021
regulation of osteoblast differentiation GO:0045667 14 0.021
metal ion homeostasis GO:0055065 186 0.021
regulation of cell activation GO:0050865 50 0.021
regulation of muscle system process GO:0090257 79 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
negative regulation of osteoblast differentiation GO:0045668 2 0.021
cellular ketone metabolic process GO:0042180 51 0.021
regulation of system process GO:0044057 208 0.021
response to inorganic substance GO:0010035 377 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
regulation of neuron differentiation GO:0045664 208 0.020
catabolic process GO:0009056 351 0.020
homeostatic process GO:0042592 331 0.020
response to oxygen levels GO:0070482 265 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
blood vessel morphogenesis GO:0048514 58 0.020
regulation of mesenchymal cell proliferation GO:0010464 4 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
response to peptide hormone GO:0043434 278 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
cellular catabolic process GO:0044248 295 0.019
rhythmic process GO:0048511 156 0.019
regulation of epithelial cell proliferation GO:0050678 49 0.019
apoptotic process GO:0006915 381 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
response to bacterium GO:0009617 200 0.019
female pregnancy GO:0007565 122 0.019
smooth muscle cell proliferation GO:0048659 77 0.019
regulation of cellular component organization GO:0051128 368 0.019
ras protein signal transduction GO:0007265 29 0.019
regulation of cell motility GO:2000145 131 0.018
ribonucleotide catabolic process GO:0009261 136 0.018
cellular component assembly GO:0022607 360 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
intracellular transport GO:0046907 185 0.018
regulation of neuron projection development GO:0010975 161 0.018
cellular component biogenesis GO:0044085 368 0.018
response to mechanical stimulus GO:0009612 134 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
macromolecule localization GO:0033036 252 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
cellular response to abiotic stimulus GO:0071214 85 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
protein localization GO:0008104 191 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
response to monosaccharide GO:0034284 159 0.017
neuron development GO:0048666 286 0.017
positive regulation of cell motility GO:2000147 97 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
negative regulation of developmental process GO:0051093 125 0.016
positive regulation of signal transduction GO:0009967 175 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
regulation of response to stress GO:0080134 126 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
organophosphate metabolic process GO:0019637 370 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
single organism catabolic process GO:0044712 283 0.016
response to ketone GO:1901654 182 0.016
ion transmembrane transport GO:0034220 365 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
epithelial cell proliferation GO:0050673 54 0.016
organ morphogenesis GO:0009887 75 0.015
regulation of transferase activity GO:0051338 123 0.015
positive regulation of signaling GO:0023056 270 0.015
cellular response to external stimulus GO:0071496 118 0.015
cell activation GO:0001775 97 0.015
skeletal system development GO:0001501 41 0.015
single organism reproductive process GO:0044702 297 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
nucleoside metabolic process GO:0009116 179 0.015
cell cycle checkpoint GO:0000075 2 0.015
circulatory system development GO:0072359 134 0.015
regulation of cell projection organization GO:0031344 175 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
neurological system process GO:0050877 219 0.015
multicellular organismal signaling GO:0035637 44 0.015
regulation of protein metabolic process GO:0051246 289 0.015
regulation of fat cell differentiation GO:0045598 3 0.015
muscle system process GO:0003012 115 0.015
organic cyclic compound catabolic process GO:1901361 175 0.014
cation transport GO:0006812 382 0.014
nucleotide catabolic process GO:0009166 139 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
response to decreased oxygen levels GO:0036293 237 0.014
leukocyte activation GO:0045321 76 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
positive regulation of kinase activity GO:0033674 77 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
response to cytokine GO:0034097 215 0.014
mesenchymal cell proliferation GO:0010463 4 0.014
positive regulation of protein modification process GO:0031401 142 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
response to oxidative stress GO:0006979 186 0.014
response to growth factor GO:0070848 189 0.014
connective tissue development GO:0061448 33 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
anterior posterior pattern specification GO:0009952 1 0.013
transmembrane transport GO:0055085 412 0.013
response to peptide GO:1901652 292 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
cation homeostasis GO:0055080 195 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
cell adhesion GO:0007155 110 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
regulation of kinase activity GO:0043549 117 0.013
formation of primary germ layer GO:0001704 1 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
mapk cascade GO:0000165 140 0.013
ion homeostasis GO:0050801 212 0.013
t cell activation GO:0042110 29 0.013
organic acid biosynthetic process GO:0016053 83 0.013
regulation of protein kinase activity GO:0045859 105 0.013
positive regulation of cell communication GO:0010647 271 0.013
osteoblast differentiation GO:0001649 26 0.013
response to radiation GO:0009314 137 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
regulation of cellular component movement GO:0051270 150 0.013
aromatic compound catabolic process GO:0019439 168 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
regulation of cell migration GO:0030334 128 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
cellular homeostasis GO:0019725 252 0.012
olfactory behavior GO:0042048 2 0.012
regulation of ossification GO:0030278 32 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
regulation of membrane potential GO:0042391 110 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
organophosphate catabolic process GO:0046434 148 0.012
gastrulation GO:0007369 2 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
peptidyl amino acid modification GO:0018193 126 0.012
eye morphogenesis GO:0048592 4 0.012
negative regulation of gene expression GO:0010629 199 0.012
salivary gland development GO:0007431 3 0.012
calcium ion homeostasis GO:0055074 162 0.012
cellular ion homeostasis GO:0006873 184 0.012
cell growth GO:0016049 104 0.012
mitotic cell cycle checkpoint GO:0007093 1 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
regulation of cellular localization GO:0060341 263 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
leukocyte migration GO:0050900 38 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
divalent inorganic cation transport GO:0072511 134 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
response to activity GO:0014823 73 0.011
eye development GO:0001654 50 0.011
cellular chemical homeostasis GO:0055082 247 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
nucleoside catabolic process GO:0009164 126 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
cell projection organization GO:0030030 302 0.011
cellular response to alcohol GO:0097306 87 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
response to wounding GO:0009611 254 0.011
defense response GO:0006952 194 0.011
female gonad development GO:0008585 53 0.011
immune system development GO:0002520 41 0.011
multicellular organism growth GO:0035264 1 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
lymphocyte activation GO:0046649 43 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
actin filament based process GO:0030029 86 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
response to lipopolysaccharide GO:0032496 191 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
chemosensory behavior GO:0007635 2 0.011
tube development GO:0035295 89 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
single organism biosynthetic process GO:0044711 342 0.011
camera type eye development GO:0043010 48 0.011
protein complex assembly GO:0006461 263 0.011
bmp signaling pathway GO:0030509 4 0.011
organ formation GO:0048645 3 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
response to hexose GO:0009746 144 0.011
sensory organ development GO:0007423 74 0.010
rho protein signal transduction GO:0007266 11 0.010
embryonic pattern specification GO:0009880 1 0.010
cell cycle GO:0007049 101 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
peptidyl tyrosine phosphorylation GO:0018108 72 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
response to interleukin 1 GO:0070555 55 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
metal ion transport GO:0030001 289 0.010
single organism organelle organization GO:1902589 180 0.010
positive regulation of endothelial cell migration GO:0010595 4 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
negative regulation of cell death GO:0060548 229 0.010
organelle organization GO:0006996 266 0.010
cellular cation homeostasis GO:0030003 180 0.010
response to reactive oxygen species GO:0000302 120 0.010
heart morphogenesis GO:0003007 3 0.010
salivary gland morphogenesis GO:0007435 1 0.010

Col6a3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
Human
musculoskeletal system disease DOID:17 0 0.043
Human
nervous system disease DOID:863 0 0.033
bone disease DOID:0080001 0 0.016
connective tissue disease DOID:65 0 0.016
central nervous system disease DOID:331 0 0.012
myopathy DOID:423 0 0.011
Human
muscular disease DOID:0080000 0 0.011
Human
muscle tissue disease DOID:66 0 0.011
Human
gastrointestinal system disease DOID:77 0 0.010