Rattus norvegicus

9 known processes

Col6a2

collagen, type VI, alpha 2

Col6a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to fluoride GO:1902617 3 0.443
response to growth factor GO:0070848 189 0.173
cartilage development involved in endochondral bone morphogenesis GO:0060351 3 0.169
embryonic skeletal system development GO:0048706 3 0.107
cellular response to growth factor stimulus GO:0071363 162 0.105
macromolecular complex subunit organization GO:0043933 339 0.098
Human
response to corticosteroid GO:0031960 235 0.097
response to ionizing radiation GO:0010212 59 0.086
response to estradiol GO:0032355 164 0.084
cellular response to vitamin e GO:0071306 3 0.083
endochondral bone morphogenesis GO:0060350 7 0.077
extracellular fibril organization GO:0043206 1 0.070
peptide cross linking GO:0018149 1 0.069
response to camp GO:0051591 91 0.067
collagen fibril organization GO:0030199 1 0.065
single organism biosynthetic process GO:0044711 342 0.063
response to purine containing compound GO:0014074 126 0.061
response to mechanical stimulus GO:0009612 134 0.056
positive regulation of gene expression GO:0010628 244 0.056
response to interleukin 2 GO:0070669 1 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.050
response to cytokine GO:0034097 215 0.047
muscle structure development GO:0061061 87 0.045
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.044
response to nutrient GO:0007584 248 0.044
macromolecular complex assembly GO:0065003 273 0.043
Human
response to nutrient levels GO:0031667 370 0.042
protein heterotrimerization GO:0070208 2 0.040
Human
growth plate cartilage development GO:0003417 2 0.040
tooth eruption GO:0044691 1 0.040
response to wounding GO:0009611 254 0.039
cellular component assembly GO:0022607 360 0.039
Human
cellular response to hormone stimulus GO:0032870 247 0.038
multi multicellular organism process GO:0044706 138 0.038
regulation of multicellular organismal development GO:2000026 376 0.038
response to extracellular stimulus GO:0009991 380 0.038
endochondral ossification GO:0001958 2 0.038
protein heterooligomerization GO:0051291 89 0.037
Human
cellular amine metabolic process GO:0044106 38 0.037
odontogenesis GO:0042476 32 0.034
bone development GO:0060348 25 0.034
cellular response to abiotic stimulus GO:0071214 85 0.034
response to oxygen levels GO:0070482 265 0.034
response to acid chemical GO:0001101 222 0.033
muscle organ development GO:0007517 50 0.032
response to organophosphorus GO:0046683 102 0.031
reproductive process GO:0022414 372 0.031
growth GO:0040007 165 0.030
cellular response to organic cyclic compound GO:0071407 202 0.030
cellular response to nicotine GO:0071316 7 0.030
response to glucocorticoid GO:0051384 223 0.029
cartilage development GO:0051216 22 0.029
protein oligomerization GO:0051259 191 0.029
Human
cellular response to interleukin 2 GO:0071352 1 0.028
female pregnancy GO:0007565 122 0.028
muscle tissue development GO:0060537 58 0.028
tissue development GO:0009888 252 0.028
protein complex assembly GO:0006461 263 0.027
Human
cellular response to lipid GO:0071396 201 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.027
protein complex subunit organization GO:0071822 302 0.027
Human
response to hyperoxia GO:0055093 45 0.027
rna biosynthetic process GO:0032774 380 0.026
response to vitamin GO:0033273 131 0.026
carboxylic acid metabolic process GO:0019752 289 0.026
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.025
urogenital system development GO:0001655 78 0.025
cation homeostasis GO:0055080 195 0.025
artery development GO:0060840 3 0.024
connective tissue development GO:0061448 33 0.024
cellular response to mechanical stimulus GO:0071260 48 0.023
chemical homeostasis GO:0048878 292 0.023
skeletal system morphogenesis GO:0048705 12 0.023
regulation of protein metabolic process GO:0051246 289 0.023
response to other organism GO:0051707 220 0.023
ossification GO:0001503 70 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
regeneration GO:0031099 163 0.023
cellular response to metal ion GO:0071248 55 0.022
cellular response to external stimulus GO:0071496 118 0.022
response to inorganic substance GO:0010035 377 0.022
response to transforming growth factor beta GO:0071559 46 0.021
regulation of cell motility GO:2000145 131 0.021
cellular response to glucocorticoid stimulus GO:0071385 68 0.020
regulation of rna metabolic process GO:0051252 391 0.020
kidney development GO:0001822 67 0.020
ras protein signal transduction GO:0007265 29 0.020
response to radiation GO:0009314 137 0.020
multi organism reproductive process GO:0044703 262 0.020
cellular response to cytokine stimulus GO:0071345 127 0.020
positive regulation of endothelial cell migration GO:0010595 4 0.019
positive regulation of stem cell differentiation GO:2000738 2 0.019
response to increased oxygen levels GO:0036296 45 0.019
rna metabolic process GO:0016070 406 0.019
cellular response to nutrient GO:0031670 30 0.019
multicellular organism reproduction GO:0032504 233 0.019
extracellular matrix organization GO:0030198 13 0.019
response to catecholamine GO:0071869 16 0.018
metal ion homeostasis GO:0055065 186 0.018
lipid metabolic process GO:0006629 283 0.018
skeletal system development GO:0001501 41 0.018
renal system development GO:0072001 67 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
head development GO:0060322 247 0.017
cellular response to tumor necrosis factor GO:0071356 46 0.017
secretion by cell GO:0032940 248 0.017
cellular response to acid chemical GO:0071229 75 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
response to peptide GO:1901652 292 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
proteolysis GO:0006508 175 0.017
wound healing GO:0042060 122 0.016
regulation of ossification GO:0030278 32 0.016
epithelial cell differentiation GO:0030855 71 0.016
epithelium development GO:0060429 96 0.016
positive regulation of developmental process GO:0051094 283 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
defense response GO:0006952 194 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
regulation of epithelial to mesenchymal transition GO:0010717 2 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
protein homooligomerization GO:0051260 91 0.015
skin morphogenesis GO:0043589 2 0.015
response to monosaccharide GO:0034284 159 0.015
striated muscle tissue development GO:0014706 58 0.015
cellular homeostasis GO:0019725 252 0.015
muscle tissue morphogenesis GO:0060415 1 0.015
organic acid metabolic process GO:0006082 292 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.014
response to activity GO:0014823 73 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
single organism reproductive process GO:0044702 297 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
cellular ion homeostasis GO:0006873 184 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
defense response to gram negative bacterium GO:0050829 3 0.014
oxoacid metabolic process GO:0043436 290 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
cellular component biogenesis GO:0044085 368 0.014
Human
cellular response to nutrient levels GO:0031669 60 0.014
response to ketone GO:1901654 182 0.014
aging GO:0007568 241 0.013
response to estrogen GO:0043627 232 0.013
cellular chemical homeostasis GO:0055082 247 0.013
embryo implantation GO:0007566 15 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
regulation of immune response GO:0050776 55 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
response to retinoic acid GO:0032526 63 0.013
cellular response to peptide GO:1901653 133 0.013
response to external biotic stimulus GO:0043207 221 0.013
amine metabolic process GO:0009308 38 0.013
reproduction GO:0000003 245 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
regulation of signal transduction GO:0009966 318 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
osteoblast differentiation GO:0001649 26 0.013
transcription dna templated GO:0006351 377 0.013
response to vitamin e GO:0033197 24 0.012
protein complex biogenesis GO:0070271 263 0.012
Human
transmembrane transport GO:0055085 412 0.012
negative regulation of metabolic process GO:0009892 331 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
response to oxidative stress GO:0006979 186 0.012
cellular response to fluoride GO:1902618 1 0.011
response to tumor necrosis factor GO:0034612 56 0.011
regulation of nervous system development GO:0051960 264 0.011
camera type eye morphogenesis GO:0048593 2 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
cellular component movement GO:0006928 248 0.011
cellular ketone metabolic process GO:0042180 51 0.011
regulation of cell differentiation GO:0045595 320 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
negative regulation of gene expression GO:0010629 199 0.011
appendage morphogenesis GO:0035107 4 0.011
central nervous system development GO:0007417 311 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
regulation of cell development GO:0060284 263 0.010
positive regulation of response to stimulus GO:0048584 285 0.010
response to peptide hormone GO:0043434 278 0.010
developmental growth GO:0048589 100 0.010
cellular response to vitamin GO:0071295 21 0.010
circulatory system development GO:0072359 134 0.010
regulation of embryonic development GO:0045995 2 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
homeostatic process GO:0042592 331 0.010
endochondral bone growth GO:0003416 3 0.010

Col6a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.350
disease of anatomical entity DOID:7 0 0.350
Human
musculoskeletal system disease DOID:17 0 0.350
Human
connective tissue disease DOID:65 0 0.350
bone development disease DOID:0080006 0 0.175
myopathy DOID:423 0 0.045
Human
muscular disease DOID:0080000 0 0.045
Human
muscular dystrophy DOID:9884 0 0.045
Human
muscle tissue disease DOID:66 0 0.045
Human
osteochondrodysplasia DOID:2256 0 0.042
nervous system disease DOID:863 0 0.019
collagen disease DOID:854 0 0.015
ehlers danlos syndrome DOID:13359 0 0.015
central nervous system disease DOID:331 0 0.010