Rattus norvegicus

0 known processes

Irx6

iroquois homeobox 6

(Aliases: RGD1564830)

Irx6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.042
transmembrane transport GO:0055085 412 0.040
reproductive process GO:0022414 372 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
response to nutrient levels GO:0031667 370 0.038
response to extracellular stimulus GO:0009991 380 0.038
single organism reproductive process GO:0044702 297 0.036
homeostatic process GO:0042592 331 0.034
response to inorganic substance GO:0010035 377 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
cellular component biogenesis GO:0044085 368 0.034
organic acid metabolic process GO:0006082 292 0.033
oxoacid metabolic process GO:0043436 290 0.033
intracellular signal transduction GO:0035556 314 0.032
carboxylic acid metabolic process GO:0019752 289 0.032
regulation of cell proliferation GO:0042127 359 0.032
cellular component assembly GO:0022607 360 0.032
ion transmembrane transport GO:0034220 365 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
apoptotic process GO:0006915 381 0.030
organophosphate metabolic process GO:0019637 370 0.030
central nervous system development GO:0007417 311 0.029
aging GO:0007568 241 0.029
secretion GO:0046903 307 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
Rat
anion transport GO:0006820 178 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
cell cell signaling GO:0007267 335 0.029
regulation of molecular function GO:0065009 398 0.029
programmed cell death GO:0012501 392 0.028
regulation of cell differentiation GO:0045595 320 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
response to decreased oxygen levels GO:0036293 237 0.027
cellular amine metabolic process GO:0044106 38 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
rna biosynthetic process GO:0032774 380 0.027
protein complex subunit organization GO:0071822 302 0.027
metal ion transport GO:0030001 289 0.027
nucleic acid templated transcription GO:0097659 379 0.027
regulation of rna metabolic process GO:0051252 391 0.027
multicellular organism reproduction GO:0032504 233 0.027
multi organism reproductive process GO:0044703 262 0.027
regulation of transcription dna templated GO:0006355 374 0.026
response to peptide GO:1901652 292 0.026
protein complex assembly GO:0006461 263 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
protein complex biogenesis GO:0070271 263 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
positive regulation of developmental process GO:0051094 283 0.026
chemical homeostasis GO:0048878 292 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
regulation of signal transduction GO:0009966 318 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
cellular response to stress GO:0033554 269 0.026
reproduction GO:0000003 245 0.026
response to oxygen levels GO:0070482 265 0.026
brain development GO:0007420 247 0.026
single organism biosynthetic process GO:0044711 342 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
regulation of programmed cell death GO:0043067 341 0.025
neuron differentiation GO:0030182 368 0.025
macromolecular complex assembly GO:0065003 273 0.025
cellular chemical homeostasis GO:0055082 247 0.025
rna metabolic process GO:0016070 406 0.025
rhythmic process GO:0048511 156 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
cellular homeostasis GO:0019725 252 0.025
response to acid chemical GO:0001101 222 0.025
regulation of catalytic activity GO:0050790 304 0.025
cellular catabolic process GO:0044248 295 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
regulation of apoptotic process GO:0042981 335 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
catabolic process GO:0009056 351 0.024
amine metabolic process GO:0009308 38 0.024
neuron development GO:0048666 286 0.024
negative regulation of metabolic process GO:0009892 331 0.024
response to peptide hormone GO:0043434 278 0.024
nucleotide metabolic process GO:0009117 279 0.024
response to metal ion GO:0010038 253 0.024
transcription dna templated GO:0006351 377 0.024
regulation of protein metabolic process GO:0051246 289 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
regulation of phosphorylation GO:0042325 248 0.024
response to estrogen GO:0043627 232 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
protein phosphorylation GO:0006468 345 0.023
ion homeostasis GO:0050801 212 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
secretion by cell GO:0032940 248 0.023
response to ketone GO:1901654 182 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
regulation of cell development GO:0060284 263 0.023
positive regulation of biosynthetic process GO:0009891 319 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
regulation of cellular component organization GO:0051128 368 0.022
single organism catabolic process GO:0044712 283 0.022
positive regulation of signaling GO:0023056 270 0.022
positive regulation of cell communication GO:0010647 271 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
cell projection organization GO:0030030 302 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
regulation of nervous system development GO:0051960 264 0.022
nitrogen compound transport GO:0071705 229 0.022
inorganic ion transmembrane transport GO:0098660 229 0.022
cation transmembrane transport GO:0098655 263 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.021
positive regulation of molecular function GO:0044093 230 0.021
protein oligomerization GO:0051259 191 0.021
neuron projection development GO:0031175 273 0.021
synaptic transmission GO:0007268 235 0.021
response to ethanol GO:0045471 162 0.021
organic substance catabolic process GO:1901575 316 0.021
positive regulation of transport GO:0051050 245 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
positive regulation of gene expression GO:0010628 244 0.021
head development GO:0060322 247 0.021
developmental process involved in reproduction GO:0003006 159 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.020
regulation of neurogenesis GO:0050767 247 0.020
response to wounding GO:0009611 254 0.020
regulation of secretion GO:0051046 224 0.020
regulation of ion transport GO:0043269 245 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
response to hypoxia GO:0001666 231 0.019
cellular cation homeostasis GO:0030003 180 0.019
negative regulation of cell death GO:0060548 229 0.019
cellular component movement GO:0006928 248 0.019
response to oxidative stress GO:0006979 186 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
proteolysis GO:0006508 175 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
cation homeostasis GO:0055080 195 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
response to nutrient GO:0007584 248 0.019
lipid metabolic process GO:0006629 283 0.019
organelle organization GO:0006996 266 0.019
organonitrogen compound catabolic process GO:1901565 179 0.018
neurological system process GO:0050877 219 0.018
regulation of neuron differentiation GO:0045664 208 0.018
cellular ion homeostasis GO:0006873 184 0.018
purine containing compound metabolic process GO:0072521 253 0.018
anterior posterior pattern specification GO:0009952 1 0.018
response to growth factor GO:0070848 189 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
cellular ketone metabolic process GO:0042180 51 0.018
response to corticosteroid GO:0031960 235 0.018
regulation of hormone levels GO:0010817 187 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
metal ion homeostasis GO:0055065 186 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
positive regulation of nervous system development GO:0051962 178 0.018
tissue development GO:0009888 252 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
ras protein signal transduction GO:0007265 29 0.017
regulation of secretion by cell GO:1903530 208 0.017
regulation of membrane potential GO:0042391 110 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
positive regulation of cell development GO:0010720 176 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
regulation of synaptic transmission GO:0050804 141 0.017
macromolecule localization GO:0033036 252 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
oxidation reduction process GO:0055114 304 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
calcium ion homeostasis GO:0055074 162 0.017
regulation of cellular localization GO:0060341 263 0.017
positive regulation of catalytic activity GO:0043085 184 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
regulation of system process GO:0044057 208 0.016
response to bacterium GO:0009617 200 0.016
signal release GO:0023061 145 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
defense response GO:0006952 194 0.016
organic anion transport GO:0015711 132 0.016
response to glucocorticoid GO:0051384 223 0.016
behavior GO:0007610 205 0.016
organic acid transport GO:0015849 116 0.016
response to carbohydrate GO:0009743 183 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
cellular lipid metabolic process GO:0044255 208 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
reproductive structure development GO:0048608 128 0.015
sexual reproduction GO:0019953 148 0.015
locomotion GO:0040011 237 0.015
regulation of protein modification process GO:0031399 194 0.015
regulation of cell projection organization GO:0031344 175 0.015
negative regulation of gene expression GO:0010629 199 0.015
response to estradiol GO:0032355 164 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
cellular response to lipid GO:0071396 201 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
heart morphogenesis GO:0003007 3 0.015
response to other organism GO:0051707 220 0.015
circulatory system process GO:0003013 183 0.015
response to purine containing compound GO:0014074 126 0.015
single organism organelle organization GO:1902589 180 0.015
blood circulation GO:0008015 183 0.015
divalent metal ion transport GO:0070838 132 0.015
negative regulation of cell communication GO:0010648 158 0.015
multi multicellular organism process GO:0044706 138 0.015
reproductive system development GO:0061458 128 0.015
localization of cell GO:0051674 202 0.015
appendage morphogenesis GO:0035107 4 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
limb morphogenesis GO:0035108 4 0.015
cell motility GO:0048870 202 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
positive regulation of signal transduction GO:0009967 175 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
response to cytokine GO:0034097 215 0.014
regulation of anatomical structure size GO:0090066 135 0.014
carboxylic acid transport GO:0046942 115 0.014
regulation of neuron projection development GO:0010975 161 0.014
small molecule biosynthetic process GO:0044283 124 0.014
response to hexose GO:0009746 144 0.014
mapk cascade GO:0000165 140 0.014
cellular response to peptide GO:1901653 133 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
circadian rhythm GO:0007623 88 0.014
regeneration GO:0031099 163 0.014
response to biotic stimulus GO:0009607 226 0.014
establishment of tissue polarity GO:0007164 2 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
divalent inorganic cation transport GO:0072511 134 0.014
immune system process GO:0002376 204 0.014
regulation of body fluid levels GO:0050878 90 0.014
response to external biotic stimulus GO:0043207 221 0.014
cell migration GO:0016477 197 0.014
heterocycle catabolic process GO:0046700 167 0.013
response to glucose GO:0009749 136 0.013
response to monosaccharide GO:0034284 159 0.013
response to radiation GO:0009314 137 0.013
regulation of locomotion GO:0040012 148 0.013
positive regulation of protein modification process GO:0031401 142 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
protein homooligomerization GO:0051260 91 0.013
sex differentiation GO:0007548 113 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
negative regulation of transport GO:0051051 136 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
regulation of hormone secretion GO:0046883 106 0.013
cellular component morphogenesis GO:0032989 155 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
wound healing GO:0042060 122 0.013
development of primary sexual characteristics GO:0045137 107 0.013
positive regulation of ion transport GO:0043270 94 0.013
positive regulation of secretion GO:0051047 140 0.013
nucleoside metabolic process GO:0009116 179 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
neuron projection morphogenesis GO:0048812 122 0.013
axis specification GO:0009798 4 0.013
Rat
glycosyl compound metabolic process GO:1901657 182 0.013
inflammatory response GO:0006954 150 0.013
gamete generation GO:0007276 124 0.013
response to reactive oxygen species GO:0000302 120 0.013
regulation of homeostatic process GO:0032844 101 0.013
response to vitamin GO:0033273 131 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
positive regulation of cell death GO:0010942 184 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
calcium ion transport GO:0006816 131 0.013
regulation of hydrolase activity GO:0051336 143 0.013
regulation of cell migration GO:0030334 128 0.013
cell part morphogenesis GO:0032990 123 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
gastrulation GO:0007369 2 0.012
mesoderm development GO:0007498 2 0.012
regulation of cellular component movement GO:0051270 150 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
regulation of cell motility GO:2000145 131 0.012
lipid biosynthetic process GO:0008610 128 0.012
regulation of mapk cascade GO:0043408 116 0.012
cell morphogenesis GO:0000902 142 0.012
negative regulation of signaling GO:0023057 157 0.012
embryonic appendage morphogenesis GO:0035113 4 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
hormone transport GO:0009914 121 0.012
response to lipopolysaccharide GO:0032496 191 0.012
female pregnancy GO:0007565 122 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
response to organophosphorus GO:0046683 102 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
regulation of transferase activity GO:0051338 123 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
growth GO:0040007 165 0.012
response to alkaloid GO:0043279 132 0.012
single organism intracellular transport GO:1902582 166 0.012
action potential GO:0001508 54 0.012
gonad development GO:0008406 104 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
single organism behavior GO:0044708 130 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
response to insulin GO:0032868 133 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
anion transmembrane transport GO:0098656 77 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
hormone secretion GO:0046879 115 0.011
aromatic compound catabolic process GO:0019439 168 0.011
regulation of metal ion transport GO:0010959 118 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
sequestering of metal ion GO:0051238 9 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
cell projection morphogenesis GO:0048858 123 0.011
vascular process in circulatory system GO:0003018 96 0.011
cellular response to external stimulus GO:0071496 118 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
non canonical wnt signaling pathway GO:0035567 3 0.011
chemosensory behavior GO:0007635 2 0.011
negative regulation of molecular function GO:0044092 133 0.011
cytoskeleton organization GO:0007010 111 0.011
cellular response to acid chemical GO:0071229 75 0.011
male gamete generation GO:0048232 99 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
organophosphate catabolic process GO:0046434 148 0.011
vesicle mediated transport GO:0016192 181 0.011
eye morphogenesis GO:0048592 4 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
response to mechanical stimulus GO:0009612 134 0.011
gland development GO:0048732 155 0.011
regulation of kinase activity GO:0043549 117 0.011
organ regeneration GO:0031100 101 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
regulation of blood vessel size GO:0050880 89 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
embryonic pattern specification GO:0009880 1 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
cellular response to alcohol GO:0097306 87 0.011
response to camp GO:0051591 91 0.011
regulation of establishment of planar polarity GO:0090175 2 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
amide transport GO:0042886 105 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
cell type specific apoptotic process GO:0097285 134 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
fatty acid metabolic process GO:0006631 99 0.011
lipid storage GO:0019915 1 0.011
peptide transport GO:0015833 97 0.010
spermatogenesis GO:0007283 99 0.010
intracellular transport GO:0046907 185 0.010
response to toxic substance GO:0009636 133 0.010
negative regulation of innate immune response GO:0045824 4 0.010
olfactory behavior GO:0042048 2 0.010
cell adhesion GO:0007155 110 0.010
cardiovascular system development GO:0072358 134 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
transmission of nerve impulse GO:0019226 42 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
cell growth GO:0016049 104 0.010
regulation of catabolic process GO:0009894 113 0.010
regulation of blood circulation GO:1903522 110 0.010
ovulation cycle GO:0042698 67 0.010
rho protein signal transduction GO:0007266 11 0.010
forebrain development GO:0030900 98 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of neuron death GO:1901214 115 0.010
protein localization GO:0008104 191 0.010
sequestering of calcium ion GO:0051208 8 0.010
circulatory system development GO:0072359 134 0.010
regulation of blood pressure GO:0008217 83 0.010
purine containing compound catabolic process GO:0072523 138 0.010
positive regulation of mapk cascade GO:0043410 92 0.010

Irx6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.015
sensory system disease DOID:0050155 0 0.013
central nervous system disease DOID:331 0 0.010