Rattus norvegicus

32 known processes

Il18bp

interleukin 18 binding protein

(Aliases: Igifbp)

Il18bp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of response to stimulus GO:0048584 285 0.282
response to lipopolysaccharide GO:0032496 191 0.224
response to cytokine GO:0034097 215 0.207
response to bacterium GO:0009617 200 0.192
response to other organism GO:0051707 220 0.182
response to biotic stimulus GO:0009607 226 0.178
response to nutrient levels GO:0031667 370 0.124
response to external biotic stimulus GO:0043207 221 0.124
response to peptide GO:1901652 292 0.118
response to nutrient GO:0007584 248 0.103
response to extracellular stimulus GO:0009991 380 0.100
rna biosynthetic process GO:0032774 380 0.097
nucleic acid templated transcription GO:0097659 379 0.094
rna metabolic process GO:0016070 406 0.093
positive regulation of multicellular organismal process GO:0051240 387 0.089
positive regulation of signaling GO:0023056 270 0.087
regulation of phosphate metabolic process GO:0019220 349 0.085
cellular response to stress GO:0033554 269 0.083
regulation of cell differentiation GO:0045595 320 0.082
regulation of cell development GO:0060284 263 0.082
response to peptide hormone GO:0043434 278 0.078
regulation of cellular component movement GO:0051270 150 0.076
transcription from rna polymerase ii promoter GO:0006366 252 0.073
defense response GO:0006952 194 0.071
regulation of transcription dna templated GO:0006355 374 0.071
immune system process GO:0002376 204 0.070
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.067
immune response GO:0006955 104 0.066
regulation of rna metabolic process GO:0051252 391 0.065
regulation of rna biosynthetic process GO:2001141 381 0.062
positive regulation of signal transduction GO:0009967 175 0.062
response to glucocorticoid GO:0051384 223 0.062
neurological system process GO:0050877 219 0.060
positive regulation of cell communication GO:0010647 271 0.059
behavior GO:0007610 205 0.059
regulation of nervous system development GO:0051960 264 0.059
regulation of response to stress GO:0080134 126 0.058
metal ion homeostasis GO:0055065 186 0.055
positive regulation of nervous system development GO:0051962 178 0.055
homeostatic process GO:0042592 331 0.053
ion homeostasis GO:0050801 212 0.053
response to corticosteroid GO:0031960 235 0.053
gland development GO:0048732 155 0.052
regulation of locomotion GO:0040012 148 0.051
positive regulation of immune system process GO:0002684 90 0.051
carboxylic acid metabolic process GO:0019752 289 0.051
response to amino acid GO:0043200 75 0.050
aging GO:0007568 241 0.049
regulation of cell proliferation GO:0042127 359 0.048
catabolic process GO:0009056 351 0.047
lipid metabolic process GO:0006629 283 0.047
positive regulation of biosynthetic process GO:0009891 319 0.047
innate immune response GO:0045087 35 0.047
response to vitamin GO:0033273 131 0.047
response to acid chemical GO:0001101 222 0.046
neuron differentiation GO:0030182 368 0.046
regulation of multicellular organismal development GO:2000026 376 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.045
central nervous system development GO:0007417 311 0.045
macromolecular complex subunit organization GO:0043933 339 0.044
cellular homeostasis GO:0019725 252 0.044
cellular ion homeostasis GO:0006873 184 0.044
regulation of phosphorylation GO:0042325 248 0.043
amine metabolic process GO:0009308 38 0.043
reproductive process GO:0022414 372 0.043
regulation of nucleic acid templated transcription GO:1903506 380 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.042
positive regulation of developmental process GO:0051094 283 0.042
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.042
negative regulation of cell death GO:0060548 229 0.041
intracellular signal transduction GO:0035556 314 0.041
negative regulation of multicellular organismal process GO:0051241 203 0.040
regulation of behavior GO:0050795 61 0.039
brain development GO:0007420 247 0.039
cellular catabolic process GO:0044248 295 0.039
response to inorganic substance GO:0010035 377 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
cellular ketone metabolic process GO:0042180 51 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
cell migration GO:0016477 197 0.038
regulation of neuron death GO:1901214 115 0.038
response to camp GO:0051591 91 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.037
rhythmic process GO:0048511 156 0.037
cellular cation homeostasis GO:0030003 180 0.036
acute inflammatory response GO:0002526 58 0.036
macromolecular complex assembly GO:0065003 273 0.036
macromolecule localization GO:0033036 252 0.036
cellular component movement GO:0006928 248 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.036
regulation of intracellular signal transduction GO:1902531 218 0.036
response to molecule of bacterial origin GO:0002237 194 0.036
intracellular transport GO:0046907 185 0.035
cation homeostasis GO:0055080 195 0.035
response to metal ion GO:0010038 253 0.035
cellular amine metabolic process GO:0044106 38 0.035
response to growth factor GO:0070848 189 0.035
oxoacid metabolic process GO:0043436 290 0.035
response to purine containing compound GO:0014074 126 0.035
neuron death GO:0070997 127 0.035
response to carbohydrate GO:0009743 183 0.035
positive regulation of rna biosynthetic process GO:1902680 197 0.034
regulation of cellular component organization GO:0051128 368 0.034
protein complex assembly GO:0006461 263 0.034
inflammatory response GO:0006954 150 0.034
response to hydrogen peroxide GO:0042542 89 0.034
cellular response to lipid GO:0071396 201 0.034
protein complex biogenesis GO:0070271 263 0.034
organophosphate metabolic process GO:0019637 370 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
protein transport GO:0015031 132 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
circulatory system process GO:0003013 183 0.033
positive regulation of neurogenesis GO:0050769 165 0.032
transcription dna templated GO:0006351 377 0.032
cellular component assembly GO:0022607 360 0.032
response to wounding GO:0009611 254 0.032
response to mechanical stimulus GO:0009612 134 0.032
positive regulation of cell development GO:0010720 176 0.032
anion transport GO:0006820 178 0.032
positive regulation of response to external stimulus GO:0032103 51 0.031
tissue development GO:0009888 252 0.031
regulation of programmed cell death GO:0043067 341 0.031
organic acid metabolic process GO:0006082 292 0.031
protein phosphorylation GO:0006468 345 0.031
positive regulation of cell differentiation GO:0045597 217 0.030
multi organism reproductive process GO:0044703 262 0.030
negative regulation of metabolic process GO:0009892 331 0.030
cellular response to growth factor stimulus GO:0071363 162 0.030
regulation of cell migration GO:0030334 128 0.030
negative regulation of gene expression GO:0010629 199 0.030
immune effector process GO:0002252 53 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
response to temperature stimulus GO:0009266 94 0.029
protein localization GO:0008104 191 0.029
protein complex subunit organization GO:0071822 302 0.029
positive regulation of gene expression GO:0010628 244 0.029
regulation of neurogenesis GO:0050767 247 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
organelle organization GO:0006996 266 0.028
cellular response to organic cyclic compound GO:0071407 202 0.028
neuron development GO:0048666 286 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
reactive oxygen species biosynthetic process GO:1903409 8 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
regulation of immune system process GO:0002682 123 0.028
cellular response to cytokine stimulus GO:0071345 127 0.028
regulation of protein modification process GO:0031399 194 0.028
negative regulation of developmental process GO:0051093 125 0.028
regulation of protein metabolic process GO:0051246 289 0.028
response to radiation GO:0009314 137 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
regulation of hormone levels GO:0010817 187 0.027
response to oxidative stress GO:0006979 186 0.027
positive regulation of neuron differentiation GO:0045666 126 0.027
response to ethanol GO:0045471 162 0.027
purine containing compound metabolic process GO:0072521 253 0.027
cellular chemical homeostasis GO:0055082 247 0.027
regulation of response to external stimulus GO:0032101 106 0.026
response to interleukin 1 GO:0070555 55 0.026
regulation of catalytic activity GO:0050790 304 0.026
cardiovascular system development GO:0072358 134 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
lipid biosynthetic process GO:0008610 128 0.026
negative regulation of rna metabolic process GO:0051253 123 0.026
cell projection organization GO:0030030 302 0.025
amide transport GO:0042886 105 0.025
programmed cell death GO:0012501 392 0.025
cellular response to biotic stimulus GO:0071216 59 0.025
cellular lipid metabolic process GO:0044255 208 0.025
cell motility GO:0048870 202 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
head development GO:0060322 247 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.025
multicellular organism reproduction GO:0032504 233 0.024
single organism intracellular transport GO:1902582 166 0.024
single organism biosynthetic process GO:0044711 342 0.024
proteolysis GO:0006508 175 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
learning or memory GO:0007611 90 0.024
regulation of chemotaxis GO:0050920 29 0.024
regulation of molecular function GO:0065009 398 0.024
single organism reproductive process GO:0044702 297 0.024
cytokine mediated signaling pathway GO:0019221 43 0.024
fatty acid metabolic process GO:0006631 99 0.024
reproduction GO:0000003 245 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
localization of cell GO:0051674 202 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
response to estrogen GO:0043627 232 0.023
response to ketone GO:1901654 182 0.023
cognition GO:0050890 92 0.023
nitrogen compound transport GO:0071705 229 0.023
locomotion GO:0040011 237 0.023
cellular response to oxidative stress GO:0034599 76 0.023
anatomical structure morphogenesis GO:0009653 298 0.022
organic substance catabolic process GO:1901575 316 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
chemical homeostasis GO:0048878 292 0.022
single organism catabolic process GO:0044712 283 0.022
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
response to organophosphorus GO:0046683 102 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
positive regulation of defense response GO:0031349 37 0.021
cytosolic calcium ion homeostasis GO:0051480 140 0.021
intracellular protein transport GO:0006886 79 0.021
reactive nitrogen species metabolic process GO:2001057 1 0.021
spindle organization GO:0007051 2 0.021
cellular component biogenesis GO:0044085 368 0.021
neuron projection development GO:0031175 273 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
single organism organelle organization GO:1902589 180 0.021
regulation of cell morphogenesis GO:0022604 77 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
developmental process involved in reproduction GO:0003006 159 0.021
response to decreased oxygen levels GO:0036293 237 0.021
response to reactive oxygen species GO:0000302 120 0.020
single organism behavior GO:0044708 130 0.020
regulation of neuron differentiation GO:0045664 208 0.020
positive regulation of cell death GO:0010942 184 0.020
negative regulation of innate immune response GO:0045824 4 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
establishment of protein localization GO:0045184 141 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.019
organic hydroxy compound metabolic process GO:1901615 115 0.019
positive regulation of mapk cascade GO:0043410 92 0.019
regulation of cell motility GO:2000145 131 0.019
blood circulation GO:0008015 183 0.019
gastrulation GO:0007369 2 0.019
hormone metabolic process GO:0042445 69 0.019
regulation of defense response GO:0031347 68 0.019
sodium ion transport GO:0006814 82 0.019
organic anion transport GO:0015711 132 0.019
regulation of signal transduction GO:0009966 318 0.019
regulation of secretion by cell GO:1903530 208 0.019
glycosyl compound metabolic process GO:1901657 182 0.018
defense response to gram positive bacterium GO:0050830 2 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.018
response to oxygen levels GO:0070482 265 0.018
response to monosaccharide GO:0034284 159 0.018
glial cell differentiation GO:0010001 65 0.018
response to glucose GO:0009749 136 0.018
secretion GO:0046903 307 0.018
response to interferon gamma GO:0034341 20 0.018
liver development GO:0001889 90 0.018
cell cell signaling GO:0007267 335 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
salivary gland development GO:0007431 3 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
cation transport GO:0006812 382 0.017
lipid catabolic process GO:0016042 46 0.017
development of primary sexual characteristics GO:0045137 107 0.017
t cell tolerance induction GO:0002517 3 0.017
cellular response to molecule of bacterial origin GO:0071219 56 0.017
metal ion transport GO:0030001 289 0.017
cytoplasmic transport GO:0016482 115 0.017
regulation of immune response GO:0050776 55 0.017
peptide transport GO:0015833 97 0.017
cellular response to tumor necrosis factor GO:0071356 46 0.017
negative regulation of cell communication GO:0010648 158 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
maintenance of location GO:0051235 17 0.017
organic acid transport GO:0015849 116 0.017
ras protein signal transduction GO:0007265 29 0.017
circulatory system development GO:0072359 134 0.017
signal transduction by phosphorylation GO:0023014 144 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
apoptotic process GO:0006915 381 0.016
positive regulation of molecular function GO:0044093 230 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
transmembrane transport GO:0055085 412 0.016
regulation of mapk cascade GO:0043408 116 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
protein oligomerization GO:0051259 191 0.016
response to ammonium ion GO:0060359 71 0.016
regulation of apoptotic process GO:0042981 335 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
gonad development GO:0008406 104 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
jak stat cascade GO:0007259 26 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
gliogenesis GO:0042063 93 0.015
regulation of organelle organization GO:0033043 80 0.015
response to hexose GO:0009746 144 0.015
circadian rhythm GO:0007623 88 0.015
multicellular organism growth GO:0035264 1 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
regeneration GO:0031099 163 0.015
positive regulation of cytokine production GO:0001819 42 0.015
regulation of cell projection organization GO:0031344 175 0.015
carboxylic acid transport GO:0046942 115 0.015
regulation of ion transport GO:0043269 245 0.015
cellular response to external stimulus GO:0071496 118 0.014
cellular response to lipopolysaccharide GO:0071222 55 0.014
cell projection morphogenesis GO:0048858 123 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
regulation of hydrolase activity GO:0051336 143 0.014
sexual reproduction GO:0019953 148 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
negative regulation of molecular function GO:0044092 133 0.014
defense response to gram negative bacterium GO:0050829 3 0.014
response to toxic substance GO:0009636 133 0.014
lipid storage GO:0019915 1 0.014
regulation of body fluid levels GO:0050878 90 0.014
cytokine production GO:0001816 61 0.014
hepaticobiliary system development GO:0061008 90 0.014
response to alkaloid GO:0043279 132 0.014
response to tumor necrosis factor GO:0034612 56 0.014
sex differentiation GO:0007548 113 0.013
protein homooligomerization GO:0051260 91 0.013
regulation of cellular localization GO:0060341 263 0.013
positive regulation of protein modification process GO:0031401 142 0.013
leukocyte activation GO:0045321 76 0.013
blood vessel morphogenesis GO:0048514 58 0.013
response to heat GO:0009408 60 0.013
ion transmembrane transport GO:0034220 365 0.013
cell type specific apoptotic process GO:0097285 134 0.013
nucleoside metabolic process GO:0009116 179 0.013
negative regulation of signaling GO:0023057 157 0.013
wound healing GO:0042060 122 0.013
positive regulation of immune response GO:0050778 42 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
cellular response to nutrient levels GO:0031669 60 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
regulation of transferase activity GO:0051338 123 0.013
olfactory behavior GO:0042048 2 0.013
secretion by cell GO:0032940 248 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
myeloid leukocyte activation GO:0002274 36 0.013
chemotaxis GO:0006935 66 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
nucleotide metabolic process GO:0009117 279 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
regulation of secretion GO:0051046 224 0.013
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.013
response to estradiol GO:0032355 164 0.013
cell part morphogenesis GO:0032990 123 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
negative regulation of programmed cell death GO:0043069 183 0.012
negative regulation of cell development GO:0010721 82 0.012
positive regulation of behavior GO:0048520 38 0.012
response to virus GO:0009615 17 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
response to hypoxia GO:0001666 231 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
organ morphogenesis GO:0009887 75 0.012
response to nicotine GO:0035094 51 0.012
growth GO:0040007 165 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
axis specification GO:0009798 4 0.012
defense response to other organism GO:0098542 17 0.012
regulation of protein transport GO:0051223 68 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
response to insulin GO:0032868 133 0.012
mitotic spindle organization GO:0007052 2 0.012
innate immune response activating signal transduction GO:0002758 9 0.012
taxis GO:0042330 67 0.012
cellular component morphogenesis GO:0032989 155 0.012
response to ionizing radiation GO:0010212 59 0.012
positive regulation of catalytic activity GO:0043085 184 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
acute phase response GO:0006953 20 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
regulation of peptide transport GO:0090087 87 0.011
regulation of homeostatic process GO:0032844 101 0.011
positive regulation of protein transport GO:0051222 41 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
memory GO:0007613 54 0.011
cell chemotaxis GO:0060326 31 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
gamete generation GO:0007276 124 0.011
regulation of kinase activity GO:0043549 117 0.011
neuron projection morphogenesis GO:0048812 122 0.011
regulation of interferon gamma production GO:0032649 3 0.011
regulation of transmembrane transport GO:0034762 122 0.011
embryonic pattern specification GO:0009880 1 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
negative regulation of viral process GO:0048525 4 0.011
regulation of response to wounding GO:1903034 69 0.011
organ regeneration GO:0031100 101 0.011
peptide secretion GO:0002790 86 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
alcohol metabolic process GO:0006066 77 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
calcium ion homeostasis GO:0055074 162 0.011
developmental growth GO:0048589 100 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
anterior posterior pattern specification GO:0009952 1 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
cellular response to organonitrogen compound GO:0071417 197 0.010
eye morphogenesis GO:0048592 4 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
female pregnancy GO:0007565 122 0.010
actin filament based process GO:0030029 86 0.010
cellular response to reactive oxygen species GO:0034614 55 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
regulation of neuron projection development GO:0010975 161 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
regulation of anatomical structure size GO:0090066 135 0.010
positive regulation of transport GO:0051050 245 0.010
cellular response to interleukin 1 GO:0071347 37 0.010
cell cycle checkpoint GO:0000075 2 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
neuron apoptotic process GO:0051402 88 0.010

Il18bp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.013
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.013
nervous system disease DOID:863 0 0.011
disease of metabolism DOID:0014667 0 0.011
gastrointestinal system cancer DOID:3119 0 0.010
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010