Rattus norvegicus

0 known processes

Bap1

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

Bap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.218
regulation of rna metabolic process GO:0051252 391 0.175
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.115
transcription from rna polymerase ii promoter GO:0006366 252 0.109
rna biosynthetic process GO:0032774 380 0.107
regulation of transcription dna templated GO:0006355 374 0.106
cell fate determination GO:0001709 2 0.105
protein phosphorylation GO:0006468 345 0.099
organelle organization GO:0006996 266 0.088
negative regulation of signaling GO:0023057 157 0.088
positive regulation of cellular biosynthetic process GO:0031328 295 0.087
regulation of rna biosynthetic process GO:2001141 381 0.086
transcription dna templated GO:0006351 377 0.079
positive regulation of transcription dna templated GO:0045893 197 0.075
single organism organelle organization GO:1902589 180 0.075
positive regulation of cellular protein metabolic process GO:0032270 167 0.069
positive regulation of gene expression GO:0010628 244 0.066
axis specification GO:0009798 4 0.065
g protein coupled receptor signaling pathway GO:0007186 242 0.063
organophosphate metabolic process GO:0019637 370 0.062
regulation of cellular amine metabolic process GO:0033238 8 0.059
positive regulation of nucleic acid templated transcription GO:1903508 197 0.059
single organism intracellular transport GO:1902582 166 0.056
intracellular protein transport GO:0006886 79 0.055
regulation of cellular ketone metabolic process GO:0010565 27 0.054
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.051
oxoacid metabolic process GO:0043436 290 0.050
amine metabolic process GO:0009308 38 0.050
regulation of cellular protein metabolic process GO:0032268 267 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.047
positive regulation of rna metabolic process GO:0051254 203 0.046
regulation of nucleic acid templated transcription GO:1903506 380 0.046
positive regulation of phosphorylation GO:0042327 177 0.044
multicellular organism growth GO:0035264 1 0.044
stress activated protein kinase signaling cascade GO:0031098 37 0.043
regulation of protein phosphorylation GO:0001932 183 0.042
intracellular transport GO:0046907 185 0.041
positive regulation of protein phosphorylation GO:0001934 135 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
aging GO:0007568 241 0.039
positive regulation of biosynthetic process GO:0009891 319 0.039
nucleic acid templated transcription GO:0097659 379 0.039
positive regulation of protein metabolic process GO:0051247 178 0.038
regulation of nervous system development GO:0051960 264 0.038
neuron development GO:0048666 286 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.038
cellular response to growth factor stimulus GO:0071363 162 0.036
action potential GO:0001508 54 0.035
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.035
cell cell signaling GO:0007267 335 0.035
negative regulation of cell communication GO:0010648 158 0.034
cellular response to stress GO:0033554 269 0.034
regulation of phosphorylation GO:0042325 248 0.034
regulation of protein modification process GO:0031399 194 0.032
nuclear import GO:0051170 35 0.032
cellular protein localization GO:0034613 122 0.032
protein transport GO:0015031 132 0.031
intracellular signal transduction GO:0035556 314 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
regulation of protein metabolic process GO:0051246 289 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.031
cellular amine metabolic process GO:0044106 38 0.031
single organism reproductive process GO:0044702 297 0.031
macromolecule localization GO:0033036 252 0.030
single organism nuclear import GO:1902593 35 0.030
cytoskeleton organization GO:0007010 111 0.030
protein oligomerization GO:0051259 191 0.030
positive regulation of neuron death GO:1901216 43 0.030
reproduction GO:0000003 245 0.029
regulation of jnk cascade GO:0046328 19 0.029
regulation of kinase activity GO:0043549 117 0.029
regulation of protein serine threonine kinase activity GO:0071900 64 0.029
negative regulation of rna biosynthetic process GO:1902679 118 0.029
regulation of transferase activity GO:0051338 123 0.029
vesicle mediated transport GO:0016192 181 0.028
regulation of protein kinase activity GO:0045859 105 0.028
cell cycle checkpoint GO:0000075 2 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.028
gastrulation GO:0007369 2 0.028
positive regulation of protein modification process GO:0031401 142 0.028
positive regulation of map kinase activity GO:0043406 46 0.027
positive regulation of kinase activity GO:0033674 77 0.027
apoptotic process GO:0006915 381 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
nucleoside metabolic process GO:0009116 179 0.026
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.026
chromatin assembly or disassembly GO:0006333 1 0.026
cell growth GO:0016049 104 0.026
positive regulation of rac gtpase activity GO:0032855 5 0.026
embryonic pattern specification GO:0009880 1 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
nuclear transport GO:0051169 49 0.026
regulation of intracellular signal transduction GO:1902531 218 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
establishment of protein localization GO:0045184 141 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
positive regulation of developmental process GO:0051094 283 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
activation of protein kinase activity GO:0032147 47 0.025
reproductive process GO:0022414 372 0.024
regulation of molecular function GO:0065009 398 0.024
negative regulation of ras gtpase activity GO:0034261 2 0.024
single organism cellular localization GO:1902580 102 0.024
positive regulation of ruffle assembly GO:1900029 1 0.024
regulation of mapk cascade GO:0043408 116 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
cellular ketone metabolic process GO:0042180 51 0.023
positive regulation of cellular component movement GO:0051272 102 0.023
protein localization to nucleus GO:0034504 39 0.023
actin filament based process GO:0030029 86 0.022
lipid metabolic process GO:0006629 283 0.022
cell morphogenesis GO:0000902 142 0.022
cellular component biogenesis GO:0044085 368 0.022
protein heterooligomerization GO:0051291 89 0.021
single organism catabolic process GO:0044712 283 0.021
dna metabolic process GO:0006259 96 0.021
peptidyl amino acid modification GO:0018193 126 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
neurological system process GO:0050877 219 0.021
positive regulation of intracellular signal transduction GO:1902533 138 0.021
defense response GO:0006952 194 0.020
cell migration GO:0016477 197 0.020
negative regulation of signal transduction GO:0009968 83 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
heart morphogenesis GO:0003007 3 0.020
ras protein signal transduction GO:0007265 29 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.020
multicellular organism reproduction GO:0032504 233 0.020
stress activated mapk cascade GO:0051403 35 0.020
positive regulation of transferase activity GO:0051347 81 0.020
protein targeting GO:0006605 61 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.019
protein complex biogenesis GO:0070271 263 0.019
protein import into nucleus GO:0006606 35 0.019
positive regulation of stress activated mapk cascade GO:0032874 17 0.019
cellular component morphogenesis GO:0032989 155 0.019
multi organism reproductive process GO:0044703 262 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
positive regulation of cell motility GO:2000147 97 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
cell projection organization GO:0030030 302 0.019
cellular component assembly GO:0022607 360 0.019
regulation of programmed cell death GO:0043067 341 0.018
chromatin organization GO:0006325 34 0.018
mitotic spindle organization GO:0007052 2 0.018
positive regulation of cellular catabolic process GO:0031331 71 0.018
response to extracellular stimulus GO:0009991 380 0.018
response to wounding GO:0009611 254 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
gliogenesis GO:0042063 93 0.018
sensory organ development GO:0007423 74 0.018
negative regulation of gene expression GO:0010629 199 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
protein localization GO:0008104 191 0.018
signal release GO:0023061 145 0.018
spindle organization GO:0007051 2 0.018
cytoplasmic transport GO:0016482 115 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
positive regulation of cell communication GO:0010647 271 0.017
growth GO:0040007 165 0.017
negative regulation of cell death GO:0060548 229 0.017
regulation of cellular component movement GO:0051270 150 0.017
regulation of homeostatic process GO:0032844 101 0.017
circulatory system development GO:0072359 134 0.017
protein catabolic process GO:0030163 30 0.017
regulation of bmp signaling pathway GO:0030510 2 0.017
axon cargo transport GO:0008088 1 0.017
gamete generation GO:0007276 124 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
positive regulation of signaling GO:0023056 270 0.017
nucleotide biosynthetic process GO:0009165 98 0.017
cellular component movement GO:0006928 248 0.017
erk1 and erk2 cascade GO:0070371 48 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
positive regulation of molecular function GO:0044093 230 0.016
cyclic purine nucleotide metabolic process GO:0052652 62 0.016
organic acid metabolic process GO:0006082 292 0.016
heart development GO:0007507 72 0.016
regulation of cell migration GO:0030334 128 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
chromosome segregation GO:0007059 2 0.016
protein modification by small protein conjugation GO:0032446 31 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
carboxylic acid metabolic process GO:0019752 289 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
regulation of peptide transport GO:0090087 87 0.015
protein complex subunit organization GO:0071822 302 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
chromosome organization GO:0051276 36 0.015
response to monosaccharide GO:0034284 159 0.015
negative regulation of response to nutrient levels GO:0032108 7 0.015
positive regulation of hydrolase activity GO:0051345 86 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
microtubule based process GO:0007017 36 0.015
ensheathment of neurons GO:0007272 40 0.015
dna replication GO:0006260 37 0.015
regulation of response to stress GO:0080134 126 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
positive regulation of cyclase activity GO:0031281 15 0.015
positive regulation of signal transduction GO:0009967 175 0.015
regulation of signal transduction GO:0009966 318 0.015
establishment of protein localization to organelle GO:0072594 44 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
regulation of map kinase activity GO:0043405 53 0.015
positive regulation of photoreceptor cell differentiation GO:0046534 2 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
regulation of synaptic plasticity GO:0048167 70 0.014
negative regulation of response to external stimulus GO:0032102 37 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
positive regulation of protein kinase activity GO:0045860 73 0.014
developmental growth GO:0048589 100 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
regulation of stress activated mapk cascade GO:0032872 23 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
regulation of cell proliferation GO:0042127 359 0.014
positive regulation of lyase activity GO:0051349 15 0.014
response to carbohydrate GO:0009743 183 0.014
multicellular organismal signaling GO:0035637 44 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
regulation of apoptotic process GO:0042981 335 0.014
regulation of cellular component organization GO:0051128 368 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
regulation of cell development GO:0060284 263 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
neuron death GO:0070997 127 0.013
negative regulation of metabolic process GO:0009892 331 0.013
transmission of nerve impulse GO:0019226 42 0.013
homeostatic process GO:0042592 331 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
peptide biosynthetic process GO:0043043 3 0.013
positive regulation of gtpase activity GO:0043547 47 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
macromolecule catabolic process GO:0009057 58 0.013
2 deoxyribonucleotide biosynthetic process GO:0009265 6 0.013
positive regulation of jnk cascade GO:0046330 13 0.013
protein dna complex disassembly GO:0032986 1 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
regulation of hormone levels GO:0010817 187 0.013
muscle structure development GO:0061061 87 0.013
response to cytokine GO:0034097 215 0.012
regulation of ion transport GO:0043269 245 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
muscle system process GO:0003012 115 0.012
lipid localization GO:0010876 62 0.012
response to glucose GO:0009749 136 0.012
protein autophosphorylation GO:0046777 66 0.012
protein targeting to nucleus GO:0044744 35 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
cardiovascular system development GO:0072358 134 0.012
regulation of hormone secretion GO:0046883 106 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
regulation of cellular response to stress GO:0080135 49 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 17 0.012
formation of primary germ layer GO:0001704 1 0.012
locomotion GO:0040011 237 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
microtubule cytoskeleton organization GO:0000226 25 0.012
cellular lipid metabolic process GO:0044255 208 0.012
rho protein signal transduction GO:0007266 11 0.012
regulation of organic acid transport GO:0032890 35 0.012
regulation of cell differentiation GO:0045595 320 0.012
establishment of organelle localization GO:0051656 37 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
regulation of response to external stimulus GO:0032101 106 0.012
cell type specific apoptotic process GO:0097285 134 0.012
cellular macromolecule localization GO:0070727 122 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
positive regulation of nervous system development GO:0051962 178 0.011
neuron projection development GO:0031175 273 0.011
regulation of catabolic process GO:0009894 113 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
positive regulation of cell death GO:0010942 184 0.011
developmental process involved in reproduction GO:0003006 159 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
positive regulation of dna metabolic process GO:0051054 39 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
organic substance catabolic process GO:1901575 316 0.011
retrograde axon cargo transport GO:0008090 1 0.011
lipid storage GO:0019915 1 0.011
tube development GO:0035295 89 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
single organism biosynthetic process GO:0044711 342 0.011
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.011
eye development GO:0001654 50 0.011
regulation of anion transport GO:0044070 43 0.011
protein dephosphorylation GO:0006470 38 0.011
cell cycle GO:0007049 101 0.011
anterior posterior pattern specification GO:0009952 1 0.011
lipid modification GO:0030258 52 0.011
catabolic process GO:0009056 351 0.011
regulation of anatomical structure size GO:0090066 135 0.011
syncytium formation by plasma membrane fusion GO:0000768 3 0.011
gonad development GO:0008406 104 0.011
synaptic transmission GO:0007268 235 0.011
autophagy GO:0006914 19 0.010
programmed cell death GO:0012501 392 0.010
regulation of peptide secretion GO:0002791 82 0.010
cellular amino acid metabolic process GO:0006520 107 0.010
macroautophagy GO:0016236 4 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.010
asymmetric protein localization GO:0008105 2 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
circulatory system process GO:0003013 183 0.010
regulation of growth GO:0040008 105 0.010
chromatin disassembly GO:0031498 1 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
anterograde axon cargo transport GO:0008089 1 0.010
regulation of fat cell differentiation GO:0045598 3 0.010
muscle contraction GO:0006936 88 0.010
positive regulation of cell development GO:0010720 176 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
embryo development GO:0009790 49 0.010
erythrocyte differentiation GO:0030218 1 0.010
mapk cascade GO:0000165 140 0.010
response to decreased oxygen levels GO:0036293 237 0.010

Bap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
thyroid carcinoma DOID:3963 0 0.011
endocrine gland cancer DOID:170 0 0.011
thyroid cancer DOID:1781 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
follicular thyroid carcinoma DOID:3962 0 0.011