Rattus norvegicus

23 known processes

Klks3

kallikrein, submaxillary gland S3

(Aliases: rGK-9,Klk9,Klk1c9,rK9)

Klks3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid biosynthetic process GO:0016053 83 0.127
protein phosphorylation GO:0006468 345 0.116
positive regulation of signaling GO:0023056 270 0.101
hormone metabolic process GO:0042445 69 0.090
circulatory system process GO:0003013 183 0.086
organic acid metabolic process GO:0006082 292 0.081
carboxylic acid metabolic process GO:0019752 289 0.066
reproductive process GO:0022414 372 0.064
multi organism reproductive process GO:0044703 262 0.064
regulation of multicellular organismal development GO:2000026 376 0.063
Rat
negative regulation of cardiac muscle tissue development GO:0055026 3 0.063
reproductive structure development GO:0048608 128 0.062
regulation of cellular component organization GO:0051128 368 0.061
Rat
oxoacid metabolic process GO:0043436 290 0.059
positive regulation of multicellular organismal process GO:0051240 387 0.057
cellular component biogenesis GO:0044085 368 0.056
carbohydrate derivative metabolic process GO:1901135 346 0.056
positive regulation of cell communication GO:0010647 271 0.052
regulation of system process GO:0044057 208 0.052
carboxylic acid biosynthetic process GO:0046394 83 0.051
regeneration GO:0031099 163 0.049
response to peptide hormone GO:0043434 278 0.049
insecticide metabolic process GO:0017143 4 0.048
small molecule biosynthetic process GO:0044283 124 0.045
reproduction GO:0000003 245 0.044
epithelial cell proliferation GO:0050673 54 0.043
single organism biosynthetic process GO:0044711 342 0.042
cell cycle GO:0007049 101 0.042
regulation of cell proliferation GO:0042127 359 0.041
g protein coupled receptor signaling pathway GO:0007186 242 0.041
regulation of hormone levels GO:0010817 187 0.039
macromolecular complex subunit organization GO:0043933 339 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.039
Mouse
cellular amino acid metabolic process GO:0006520 107 0.037
cell projection organization GO:0030030 302 0.037
Rat
peptide biosynthetic process GO:0043043 3 0.037
Mouse
neuron projection development GO:0031175 273 0.037
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
response to extracellular stimulus GO:0009991 380 0.037
Rat
regulation of neuron death GO:1901214 115 0.036
regulation of phosphorylation GO:0042325 248 0.036
Mouse
negative regulation of multicellular organismal process GO:0051241 203 0.036
catabolic process GO:0009056 351 0.034
neuron development GO:0048666 286 0.033
Rat
regulation of molecular function GO:0065009 398 0.032
Mouse
cellular response to fluid shear stress GO:0071498 4 0.032
regulation of blood circulation GO:1903522 110 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
cellular ketone metabolic process GO:0042180 51 0.031
cellular component assembly GO:0022607 360 0.031
macromolecular complex assembly GO:0065003 273 0.031
regulation of epithelial cell proliferation GO:0050678 49 0.031
cellular catabolic process GO:0044248 295 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.030
Mouse
respiratory system development GO:0060541 45 0.030
central nervous system development GO:0007417 311 0.030
cellular amino acid biosynthetic process GO:0008652 32 0.030
regulation of cell projection organization GO:0031344 175 0.029
Rat
localization of cell GO:0051674 202 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
intestinal absorption GO:0050892 3 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
positive regulation of gene expression GO:0010628 244 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
female pregnancy GO:0007565 122 0.028
tissue development GO:0009888 252 0.028
Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.027
response to purine containing compound GO:0014074 126 0.027
Rat
regulation of neurogenesis GO:0050767 247 0.027
Rat
regulation of neuron projection development GO:0010975 161 0.027
Rat
positive regulation of cell death GO:0010942 184 0.027
transmembrane transport GO:0055085 412 0.027
neuron differentiation GO:0030182 368 0.027
Rat
response to wounding GO:0009611 254 0.026
cardiovascular system development GO:0072358 134 0.026
Mouse
response to estrogen GO:0043627 232 0.026
regulation of transferase activity GO:0051338 123 0.026
Mouse
acrosome assembly GO:0001675 3 0.026
neuron death GO:0070997 127 0.025
digestive system development GO:0055123 41 0.025
olfactory learning GO:0008355 1 0.025
cell morphogenesis GO:0000902 142 0.025
single organism reproductive process GO:0044702 297 0.025
peptidyl amino acid modification GO:0018193 126 0.024
biological adhesion GO:0022610 110 0.024
gastrulation GO:0007369 2 0.024
heart morphogenesis GO:0003007 3 0.024
Mouse
cellular response to stress GO:0033554 269 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
cellular response to alcohol GO:0097306 87 0.023
regulation of blood pressure GO:0008217 83 0.023
Mouse
regulation of metal ion transport GO:0010959 118 0.023
regulation of ossification GO:0030278 32 0.023
single organism catabolic process GO:0044712 283 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
intracellular signal transduction GO:0035556 314 0.022
Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
Mouse
secretion by cell GO:0032940 248 0.022
cardiac ventricle development GO:0003231 1 0.021
Mouse
vesicle mediated transport GO:0016192 181 0.021
response to fluid shear stress GO:0034405 16 0.021
response to activity GO:0014823 73 0.021
blood circulation GO:0008015 183 0.021
cellular nitrogen compound catabolic process GO:0044270 163 0.021
dna metabolic process GO:0006259 96 0.021
regulation of ion transport GO:0043269 245 0.021
amide biosynthetic process GO:0043604 10 0.021
Mouse
cellular component morphogenesis GO:0032989 155 0.021
cardiac muscle tissue morphogenesis GO:0055008 1 0.020
Mouse
positive regulation of developmental process GO:0051094 283 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
amine metabolic process GO:0009308 38 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
cation transmembrane transport GO:0098655 263 0.020
lipid biosynthetic process GO:0008610 128 0.019
alpha amino acid metabolic process GO:1901605 71 0.019
negative regulation of organ growth GO:0046621 3 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
single organism organelle organization GO:1902589 180 0.019
ion homeostasis GO:0050801 212 0.019
sexual reproduction GO:0019953 148 0.019
oxidation reduction process GO:0055114 304 0.019
circulatory system development GO:0072359 134 0.019
Mouse
positive regulation of signal transduction GO:0009967 175 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
protein complex assembly GO:0006461 263 0.019
synapse organization GO:0050808 46 0.018
protein complex subunit organization GO:0071822 302 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
cellular amine metabolic process GO:0044106 38 0.018
response to ketone GO:1901654 182 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
Mouse
anion transport GO:0006820 178 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
ossification GO:0001503 70 0.018
alpha amino acid biosynthetic process GO:1901607 23 0.017
rna biosynthetic process GO:0032774 380 0.017
transformation of host cell by virus GO:0019087 4 0.017
negative regulation of nervous system development GO:0051961 79 0.017
rna metabolic process GO:0016070 406 0.017
regulation of cell development GO:0060284 263 0.017
Rat
brain development GO:0007420 247 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
positive regulation of cell development GO:0010720 176 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
chemosensory behavior GO:0007635 2 0.017
appendage morphogenesis GO:0035107 4 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
nucleotide metabolic process GO:0009117 279 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.016
lipid metabolic process GO:0006629 283 0.016
Mouse
olfactory behavior GO:0042048 2 0.016
tube development GO:0035295 89 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
regulation of catalytic activity GO:0050790 304 0.016
Mouse
regulation of rna metabolic process GO:0051252 391 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
programmed cell death GO:0012501 392 0.016
anterior posterior pattern specification GO:0009952 1 0.016
jak stat cascade GO:0007259 26 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
regulation of lipid metabolic process GO:0019216 68 0.016
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 88 0.015
response to insulin GO:0032868 133 0.015
peptidyl tyrosine modification GO:0018212 72 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
regulation of protein modification process GO:0031399 194 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
Mouse
wound healing GO:0042060 122 0.015
mesoderm development GO:0007498 2 0.015
fatty acid metabolic process GO:0006631 99 0.015
hormone biosynthetic process GO:0042446 25 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
multicellular organism reproduction GO:0032504 233 0.015
regulation of synaptic transmission GO:0050804 141 0.015
head development GO:0060322 247 0.015
ion transmembrane transport GO:0034220 365 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
regulation of protein phosphorylation GO:0001932 183 0.014
response to peptide GO:1901652 292 0.014
embryo development GO:0009790 49 0.014
regulation of striated muscle tissue development GO:0016202 25 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
multi multicellular organism process GO:0044706 138 0.014
steroid metabolic process GO:0008202 73 0.014
steroid biosynthetic process GO:0006694 48 0.014
response to decreased oxygen levels GO:0036293 237 0.014
lung development GO:0030324 43 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
apoptotic process GO:0006915 381 0.014
aromatic compound catabolic process GO:0019439 168 0.014
cell cell signaling GO:0007267 335 0.014
multicellular organism growth GO:0035264 1 0.014
regulation of cell differentiation GO:0045595 320 0.014
Rat
transcription dna templated GO:0006351 377 0.014
negative regulation of metabolic process GO:0009892 331 0.014
response to glucocorticoid GO:0051384 223 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
formation of primary germ layer GO:0001704 1 0.013
regulation of secretion GO:0051046 224 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
sex differentiation GO:0007548 113 0.013
maternal process involved in female pregnancy GO:0060135 38 0.013
heterocycle catabolic process GO:0046700 167 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.013
response to corticosteroid GO:0031960 235 0.013
sulfur amino acid metabolic process GO:0000096 9 0.013
regulation of signal transduction GO:0009966 318 0.013
regulation of programmed cell death GO:0043067 341 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
Mouse
regulation of ion homeostasis GO:2000021 63 0.013
cation transport GO:0006812 382 0.013
muscle structure development GO:0061061 87 0.013
Mouse
meiotic cell cycle process GO:1903046 3 0.013
cellular amide metabolic process GO:0043603 44 0.013
Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.013
response to nutrient levels GO:0031667 370 0.013
Rat
positive regulation of cell differentiation GO:0045597 217 0.012
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
calcium ion transport GO:0006816 131 0.012
cell growth GO:0016049 104 0.012
metal ion transport GO:0030001 289 0.012
regulation of growth GO:0040008 105 0.012
positive regulation of growth GO:0045927 55 0.012
organic substance catabolic process GO:1901575 316 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
response to interleukin 1 GO:0070555 55 0.012
negative regulation of serine type endopeptidase activity GO:1900004 1 0.012
regulation of developmental growth GO:0048638 45 0.012
negative regulation of growth GO:0045926 37 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
Mouse
organic hydroxy compound transport GO:0015850 77 0.012
lipid localization GO:0010876 62 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
Mouse
nucleoside monophosphate metabolic process GO:0009123 93 0.012
protein oligomerization GO:0051259 191 0.012
hindbrain morphogenesis GO:0021575 2 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
synaptic transmission GO:0007268 235 0.012
neuron neuron synaptic transmission GO:0007270 60 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
cellular component movement GO:0006928 248 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
response to lipopolysaccharide GO:0032496 191 0.011
protein complex biogenesis GO:0070271 263 0.011
single organism membrane organization GO:0044802 74 0.011
rhythmic process GO:0048511 156 0.011
positive regulation of protein modification process GO:0031401 142 0.011
cell adhesion GO:0007155 110 0.011
nucleoside metabolic process GO:0009116 179 0.011
striated muscle tissue development GO:0014706 58 0.011
Mouse
organophosphate biosynthetic process GO:0090407 143 0.011
response to estradiol GO:0032355 164 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
mesoderm morphogenesis GO:0048332 1 0.011
limb morphogenesis GO:0035108 4 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
regulation of blood vessel size GO:0050880 89 0.011
response to glucose GO:0009749 136 0.011
respiratory tube development GO:0030323 43 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.011
gamete generation GO:0007276 124 0.011
tetrapyrrole metabolic process GO:0033013 11 0.011
cellular chemical homeostasis GO:0055082 247 0.011
glutamine family amino acid metabolic process GO:0009064 15 0.011
locomotion GO:0040011 237 0.011
receptor metabolic process GO:0043112 18 0.011
negative regulation of secretion GO:0051048 82 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
defense response GO:0006952 194 0.011
Mouse
cell cycle checkpoint GO:0000075 2 0.011
axon development GO:0061564 96 0.011
cellular cation homeostasis GO:0030003 180 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
kidney development GO:0001822 67 0.011
regulation of anatomical structure size GO:0090066 135 0.010
cell projection morphogenesis GO:0048858 123 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
embryonic pattern specification GO:0009880 1 0.010
organic acid transport GO:0015849 116 0.010
positive regulation of response to stimulus GO:0048584 285 0.010
negative regulation of transport GO:0051051 136 0.010
vascular process in circulatory system GO:0003018 96 0.010
spindle organization GO:0007051 2 0.010
male gamete generation GO:0048232 99 0.010
rho protein signal transduction GO:0007266 11 0.010
regulation of cell adhesion GO:0030155 52 0.010
chromosome segregation GO:0007059 2 0.010
muscle system process GO:0003012 115 0.010
Mouse
multicellular organismal response to stress GO:0033555 25 0.010
protein autophosphorylation GO:0046777 66 0.010
carboxylic acid transport GO:0046942 115 0.010
endocytosis GO:0006897 84 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
purine containing compound metabolic process GO:0072521 253 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
negative regulation of heart growth GO:0061117 3 0.010
negative regulation of molecular function GO:0044092 133 0.010
regulation of protein metabolic process GO:0051246 289 0.010
pteridine containing compound metabolic process GO:0042558 14 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
divalent metal ion transport GO:0070838 132 0.010

Klks3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
musculoskeletal system disease DOID:17 0 0.045
muscle tissue disease DOID:66 0 0.025
muscular disease DOID:0080000 0 0.025
cardiovascular system disease DOID:1287 0 0.020
sensory system disease DOID:0050155 0 0.014
nervous system disease DOID:863 0 0.014
myopathy DOID:423 0 0.013
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011