Rattus norvegicus

0 known processes

Lrrc4

leucine rich repeat containing 4

Lrrc4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
homeostatic process GO:0042592 331 0.063
neuron development GO:0048666 286 0.062
neuron differentiation GO:0030182 368 0.061
cellular response to oxygen containing compound GO:1901701 386 0.061
cellular component assembly GO:0022607 360 0.060
cellular component biogenesis GO:0044085 368 0.059
regulation of rna metabolic process GO:0051252 391 0.058
oxoacid metabolic process GO:0043436 290 0.056
rna metabolic process GO:0016070 406 0.055
regulation of nervous system development GO:0051960 264 0.054
programmed cell death GO:0012501 392 0.054
regulation of rna biosynthetic process GO:2001141 381 0.053
carbohydrate derivative metabolic process GO:1901135 346 0.051
regulation of cell development GO:0060284 263 0.050
cellular response to stress GO:0033554 269 0.048
protein complex assembly GO:0006461 263 0.047
organic substance catabolic process GO:1901575 316 0.046
regulation of molecular function GO:0065009 398 0.046
response to nutrient levels GO:0031667 370 0.045
protein complex subunit organization GO:0071822 302 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.044
regulation of catalytic activity GO:0050790 304 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
regulation of programmed cell death GO:0043067 341 0.042
regulation of multicellular organismal development GO:2000026 376 0.041
response to oxidative stress GO:0006979 186 0.040
positive regulation of developmental process GO:0051094 283 0.040
response to extracellular stimulus GO:0009991 380 0.040
reproductive process GO:0022414 372 0.039
regulation of transcription dna templated GO:0006355 374 0.039
amine metabolic process GO:0009308 38 0.038
nucleic acid templated transcription GO:0097659 379 0.038
macromolecular complex subunit organization GO:0043933 339 0.037
apoptotic process GO:0006915 381 0.037
neuron projection development GO:0031175 273 0.037
regulation of apoptotic process GO:0042981 335 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.037
transcription from rna polymerase ii promoter GO:0006366 252 0.036
catabolic process GO:0009056 351 0.036
multicellular organismal reproductive process GO:0048609 233 0.035
central nervous system development GO:0007417 311 0.035
single organism reproductive process GO:0044702 297 0.034
rna biosynthetic process GO:0032774 380 0.034
single organism catabolic process GO:0044712 283 0.034
regulation of cell differentiation GO:0045595 320 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
transcription dna templated GO:0006351 377 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
cellular ketone metabolic process GO:0042180 51 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
regulation of signal transduction GO:0009966 318 0.032
macromolecule localization GO:0033036 252 0.032
Mouse
reproduction GO:0000003 245 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
response to estrogen GO:0043627 232 0.032
divalent metal ion transport GO:0070838 132 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
head development GO:0060322 247 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
anion transport GO:0006820 178 0.031
organic acid metabolic process GO:0006082 292 0.030
regulation of intracellular signal transduction GO:1902531 218 0.030
negative regulation of cellular biosynthetic process GO:0031327 161 0.030
purine containing compound metabolic process GO:0072521 253 0.030
organonitrogen compound catabolic process GO:1901565 179 0.030
cellular amine metabolic process GO:0044106 38 0.030
response to oxygen levels GO:0070482 265 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
anatomical structure morphogenesis GO:0009653 298 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.029
regulation of cell proliferation GO:0042127 359 0.029
chemical homeostasis GO:0048878 292 0.029
cation transport GO:0006812 382 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
cellular catabolic process GO:0044248 295 0.029
positive regulation of cell development GO:0010720 176 0.029
protein complex biogenesis GO:0070271 263 0.028
defense response GO:0006952 194 0.028
brain development GO:0007420 247 0.028
positive regulation of molecular function GO:0044093 230 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
carboxylic acid metabolic process GO:0019752 289 0.028
negative regulation of metabolic process GO:0009892 331 0.028
macromolecular complex assembly GO:0065003 273 0.028
regulation of cellular component organization GO:0051128 368 0.028
Mouse
intracellular signal transduction GO:0035556 314 0.027
organelle organization GO:0006996 266 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
cellular component morphogenesis GO:0032989 155 0.027
developmental process involved in reproduction GO:0003006 159 0.027
cellular response to external stimulus GO:0071496 118 0.027
purine nucleoside metabolic process GO:0042278 169 0.027
cellular chemical homeostasis GO:0055082 247 0.027
response to nutrient GO:0007584 248 0.026
regulation of cell projection organization GO:0031344 175 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
organic cyclic compound catabolic process GO:1901361 175 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
cell projection organization GO:0030030 302 0.025
cellular response to lipid GO:0071396 201 0.025
cell motility GO:0048870 202 0.025
nucleotide catabolic process GO:0009166 139 0.025
protein phosphorylation GO:0006468 345 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
positive regulation of cell communication GO:0010647 271 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
sexual reproduction GO:0019953 148 0.024
aromatic compound catabolic process GO:0019439 168 0.024
multi organism reproductive process GO:0044703 262 0.024
multicellular organism reproduction GO:0032504 233 0.024
protein oligomerization GO:0051259 191 0.024
dendrite development GO:0016358 72 0.023
divalent inorganic cation transport GO:0072511 134 0.023
response to growth factor GO:0070848 189 0.023
response to carbohydrate GO:0009743 183 0.023
negative regulation of signaling GO:0023057 157 0.023
organic acid transport GO:0015849 116 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
heterocycle catabolic process GO:0046700 167 0.023
glycosyl compound metabolic process GO:1901657 182 0.023
cellular homeostasis GO:0019725 252 0.023
regulation of hormone levels GO:0010817 187 0.023
organophosphate metabolic process GO:0019637 370 0.023
purine nucleotide catabolic process GO:0006195 136 0.023
nucleoside metabolic process GO:0009116 179 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
response to inorganic substance GO:0010035 377 0.022
regulation of ion transport GO:0043269 245 0.022
axis specification GO:0009798 4 0.022
response to ethanol GO:0045471 162 0.022
purine ribonucleotide catabolic process GO:0009154 136 0.022
regulation of neurogenesis GO:0050767 247 0.022
action potential GO:0001508 54 0.022
intracellular transport GO:0046907 185 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.021
secretion GO:0046903 307 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
forebrain development GO:0030900 98 0.021
single organism organelle organization GO:1902589 180 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
lipid metabolic process GO:0006629 283 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
reproductive structure development GO:0048608 128 0.021
circulatory system development GO:0072359 134 0.021
response to hexose GO:0009746 144 0.020
aging GO:0007568 241 0.020
inorganic ion transmembrane transport GO:0098660 229 0.020
nucleoside catabolic process GO:0009164 126 0.020
cell morphogenesis GO:0000902 142 0.020
response to cytokine GO:0034097 215 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
response to monosaccharide GO:0034284 159 0.020
response to estradiol GO:0032355 164 0.020
negative regulation of cell communication GO:0010648 158 0.020
response to lipopolysaccharide GO:0032496 191 0.020
cell projection morphogenesis GO:0048858 123 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
regulation of neuron differentiation GO:0045664 208 0.019
carbohydrate derivative catabolic process GO:1901136 147 0.019
cellular component movement GO:0006928 248 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
multi multicellular organism process GO:0044706 138 0.019
response to decreased oxygen levels GO:0036293 237 0.018
positive regulation of cell death GO:0010942 184 0.018
organophosphate catabolic process GO:0046434 148 0.018
immune response GO:0006955 104 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
purine containing compound catabolic process GO:0072523 138 0.018
tube development GO:0035295 89 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
carboxylic acid transport GO:0046942 115 0.018
hormone secretion GO:0046879 115 0.018
reproductive system development GO:0061458 128 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
ribonucleotide catabolic process GO:0009261 136 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
vesicle mediated transport GO:0016192 181 0.017
lipid biosynthetic process GO:0008610 128 0.017
cation transmembrane transport GO:0098655 263 0.017
transmembrane transport GO:0055085 412 0.017
embryonic axis specification GO:0000578 1 0.017
tissue development GO:0009888 252 0.017
cellular protein localization GO:0034613 122 0.017
Mouse
regulation of neuron projection development GO:0010975 161 0.017
spindle organization GO:0007051 2 0.017
hormone transport GO:0009914 121 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
negative regulation of cell death GO:0060548 229 0.017
response to biotic stimulus GO:0009607 226 0.017
neuron death GO:0070997 127 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
ion homeostasis GO:0050801 212 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
response to radiation GO:0009314 137 0.016
positive regulation of signaling GO:0023056 270 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
anterior posterior pattern specification GO:0009952 1 0.016
organic anion transport GO:0015711 132 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
response to glucocorticoid GO:0051384 223 0.016
ras protein signal transduction GO:0007265 29 0.016
response to other organism GO:0051707 220 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
organ morphogenesis GO:0009887 75 0.016
regulation of cellular component biogenesis GO:0044087 86 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
gastrulation GO:0007369 2 0.016
regulation of protein modification process GO:0031399 194 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
response to glucose GO:0009749 136 0.016
nucleotide metabolic process GO:0009117 279 0.016
female pregnancy GO:0007565 122 0.015
positive regulation of gene expression GO:0010628 244 0.015
single organism intracellular transport GO:1902582 166 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
negative regulation of signal transduction GO:0009968 83 0.015
response to corticosteroid GO:0031960 235 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
cytoplasmic transport GO:0016482 115 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
synaptic transmission GO:0007268 235 0.015
Mouse
response to temperature stimulus GO:0009266 94 0.015
embryonic pattern specification GO:0009880 1 0.015
neuron projection morphogenesis GO:0048812 122 0.015
response to external biotic stimulus GO:0043207 221 0.015
ion transmembrane transport GO:0034220 365 0.015
chemosensory behavior GO:0007635 2 0.015
regeneration GO:0031099 163 0.015
calcium ion transport GO:0006816 131 0.015
urogenital system development GO:0001655 78 0.015
response to ketone GO:1901654 182 0.015
negative regulation of transport GO:0051051 136 0.015
metal ion transport GO:0030001 289 0.015
positive regulation of nervous system development GO:0051962 178 0.015
response to alkaloid GO:0043279 132 0.014
gamete generation GO:0007276 124 0.014
heart morphogenesis GO:0003007 3 0.014
response to peptide hormone GO:0043434 278 0.014
cell part morphogenesis GO:0032990 123 0.014
regulation of protein metabolic process GO:0051246 289 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
protein transport GO:0015031 132 0.014
inflammatory response GO:0006954 150 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
blood circulation GO:0008015 183 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
localization of cell GO:0051674 202 0.014
multicellular organismal homeostasis GO:0048871 49 0.014
negative regulation of molecular function GO:0044092 133 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
response to tumor cell GO:0002347 4 0.014
peptidyl amino acid modification GO:0018193 126 0.014
cellular response to alcohol GO:0097306 87 0.013
response to hydrogen peroxide GO:0042542 89 0.013
cellular ion homeostasis GO:0006873 184 0.013
response to peptide GO:1901652 292 0.013
regulation of hydrolase activity GO:0051336 143 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
cellular cation homeostasis GO:0030003 180 0.013
negative regulation of gene expression GO:0010629 199 0.013
lipid localization GO:0010876 62 0.013
dendrite morphogenesis GO:0048813 43 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
metal ion homeostasis GO:0055065 186 0.013
response to hypoxia GO:0001666 231 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
response to acid chemical GO:0001101 222 0.013
fatty acid metabolic process GO:0006631 99 0.013
cytoskeleton organization GO:0007010 111 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
axon development GO:0061564 96 0.013
negative regulation of innate immune response GO:0045824 4 0.012
regulation of membrane potential GO:0042391 110 0.012
regulation of organelle organization GO:0033043 80 0.012
negative regulation of response to tumor cell GO:0002835 2 0.012
regulation of transferase activity GO:0051338 123 0.012
establishment of tissue polarity GO:0007164 2 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
calcium ion homeostasis GO:0055074 162 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
regulation of system process GO:0044057 208 0.012
actin cytoskeleton organization GO:0030036 73 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
positive regulation of immune system process GO:0002684 90 0.012
glucose homeostasis GO:0042593 75 0.012
protein localization GO:0008104 191 0.012
Mouse
ovulation cycle GO:0042698 67 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
establishment of protein localization GO:0045184 141 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
response to vitamin GO:0033273 131 0.012
single organism cellular localization GO:1902580 102 0.012
Mouse
regulation of secretion by cell GO:1903530 208 0.012
cardiovascular system development GO:0072358 134 0.012
regulation of cellular localization GO:0060341 263 0.012
neurological system process GO:0050877 219 0.012
response to wounding GO:0009611 254 0.012
cell cell signaling GO:0007267 335 0.012
Mouse
response to interleukin 1 GO:0070555 55 0.012
response to starvation GO:0042594 59 0.012
regulation of cell migration GO:0030334 128 0.012
cell migration GO:0016477 197 0.012
renal system development GO:0072001 67 0.012
negative regulation of transcription dna templated GO:0045892 116 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
kidney development GO:0001822 67 0.011
digestive tract development GO:0048565 39 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
locomotion GO:0040011 237 0.011
alcohol metabolic process GO:0006066 77 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
olfactory behavior GO:0042048 2 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
sulfur compound metabolic process GO:0006790 70 0.011
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.011
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.011
telencephalon development GO:0021537 62 0.011
actin filament based process GO:0030029 86 0.011
regulation of neuron death GO:1901214 115 0.011
regulation of kinase activity GO:0043549 117 0.011
secretion by cell GO:0032940 248 0.011
small molecule biosynthetic process GO:0044283 124 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
mesoderm development GO:0007498 2 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
single organism behavior GO:0044708 130 0.011
neuron apoptotic process GO:0051402 88 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
regulation of locomotion GO:0040012 148 0.011
appendage morphogenesis GO:0035107 4 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
cell growth GO:0016049 104 0.011
regulation of catabolic process GO:0009894 113 0.011
epithelium development GO:0060429 96 0.011
regulation of dendrite development GO:0050773 59 0.011
response to purine containing compound GO:0014074 126 0.011
proteolysis GO:0006508 175 0.011
regulation of phosphorylation GO:0042325 248 0.011
lipid transport GO:0006869 61 0.010
digestive system development GO:0055123 41 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
protein targeting GO:0006605 61 0.010
response to bacterium GO:0009617 200 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
signal release GO:0023061 145 0.010
single organism biosynthetic process GO:0044711 342 0.010
positive regulation of transport GO:0051050 245 0.010
rna localization GO:0006403 4 0.010
mitotic spindle organization GO:0007052 2 0.010
regulation of hormone secretion GO:0046883 106 0.010
immune system process GO:0002376 204 0.010
response to reactive oxygen species GO:0000302 120 0.010
cell type specific apoptotic process GO:0097285 134 0.010
gland development GO:0048732 155 0.010
sequestering of calcium ion GO:0051208 8 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010
palate development GO:0060021 2 0.010
spermatogenesis GO:0007283 99 0.010
regulation of response to stress GO:0080134 126 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
peptide hormone secretion GO:0030072 84 0.010
positive regulation of cellular component biogenesis GO:0044089 55 0.010
response to ammonium ion GO:0060359 71 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010

Lrrc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
disease of metabolism DOID:0014667 0 0.012
central nervous system disease DOID:331 0 0.011