Rattus norvegicus

7 known processes

Numa1

nuclear mitotic apparatus protein 1

Numa1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.099
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.095
negative regulation of biosynthetic process GO:0009890 168 0.094
rna biosynthetic process GO:0032774 380 0.088
nucleic acid templated transcription GO:0097659 379 0.080
organelle organization GO:0006996 266 0.080
negative regulation of gene expression GO:0010629 199 0.075
regulation of rna metabolic process GO:0051252 391 0.073
regulation of nucleic acid templated transcription GO:1903506 380 0.065
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.062
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.061
regulation of cell projection organization GO:0031344 175 0.057
transcription dna templated GO:0006351 377 0.055
regulation of cell differentiation GO:0045595 320 0.055
negative regulation of metabolic process GO:0009892 331 0.053
negative regulation of cellular metabolic process GO:0031324 281 0.053
negative regulation of rna metabolic process GO:0051253 123 0.053
regulation of multicellular organismal development GO:2000026 376 0.051
anterior posterior pattern specification GO:0009952 1 0.050
negative regulation of rna biosynthetic process GO:1902679 118 0.050
transcription from rna polymerase ii promoter GO:0006366 252 0.047
cell projection organization GO:0030030 302 0.047
positive regulation of multicellular organismal process GO:0051240 387 0.046
chromosome organization GO:0051276 36 0.046
regulation of neurogenesis GO:0050767 247 0.045
macromolecular complex subunit organization GO:0043933 339 0.045
negative regulation of transcription dna templated GO:0045892 116 0.045
regulation of neuron projection development GO:0010975 161 0.043
neuron differentiation GO:0030182 368 0.042
regulation of rna biosynthetic process GO:2001141 381 0.042
regulation of transcription dna templated GO:0006355 374 0.042
negative regulation of nucleic acid templated transcription GO:1903507 117 0.040
regulation of anatomical structure morphogenesis GO:0022603 141 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
negative regulation of cellular biosynthetic process GO:0031327 161 0.037
regulation of nervous system development GO:0051960 264 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
regulation of protein metabolic process GO:0051246 289 0.035
cellular amino acid metabolic process GO:0006520 107 0.034
regulation of cellular protein metabolic process GO:0032268 267 0.034
single organism behavior GO:0044708 130 0.034
programmed cell death GO:0012501 392 0.034
positive regulation of apoptotic process GO:0043065 154 0.033
regulation of neuron differentiation GO:0045664 208 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.031
response to extracellular stimulus GO:0009991 380 0.031
cellular component biogenesis GO:0044085 368 0.031
cellular component assembly GO:0022607 360 0.031
regulation of cell development GO:0060284 263 0.031
cellular amine metabolic process GO:0044106 38 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
positive regulation of nervous system development GO:0051962 178 0.030
cellular ketone metabolic process GO:0042180 51 0.030
protein transport GO:0015031 132 0.030
response to lipopolysaccharide GO:0032496 191 0.030
anatomical structure morphogenesis GO:0009653 298 0.029
regulation of cellular component organization GO:0051128 368 0.029
single organism reproductive process GO:0044702 297 0.029
behavior GO:0007610 205 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.028
positive regulation of gene expression GO:0010628 244 0.028
neuron projection development GO:0031175 273 0.028
positive regulation of neurogenesis GO:0050769 165 0.028
chromatin modification GO:0016568 33 0.028
positive regulation of cellular component organization GO:0051130 200 0.027
spindle organization GO:0007051 2 0.027
macromolecule localization GO:0033036 252 0.027
regulation of cellular localization GO:0060341 263 0.026
regulation of catalytic activity GO:0050790 304 0.026
neuron projection morphogenesis GO:0048812 122 0.026
positive regulation of cell development GO:0010720 176 0.026
cell migration GO:0016477 197 0.026
positive regulation of neuron differentiation GO:0045666 126 0.026
response to hexose GO:0009746 144 0.025
cognition GO:0050890 92 0.025
regulation of apoptotic process GO:0042981 335 0.025
response to monosaccharide GO:0034284 159 0.025
response to molecule of bacterial origin GO:0002237 194 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
protein localization GO:0008104 191 0.024
single organism organelle organization GO:1902589 180 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.024
cell part morphogenesis GO:0032990 123 0.024
positive regulation of programmed cell death GO:0043068 157 0.023
amine metabolic process GO:0009308 38 0.023
positive regulation of developmental process GO:0051094 283 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
cellular component movement GO:0006928 248 0.023
protein complex subunit organization GO:0071822 302 0.023
protein complex biogenesis GO:0070271 263 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
cell motility GO:0048870 202 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.022
cellular protein localization GO:0034613 122 0.022
motor neuron axon guidance GO:0008045 1 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.021
organic acid metabolic process GO:0006082 292 0.021
neurological system process GO:0050877 219 0.021
positive regulation of cell death GO:0010942 184 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
homeostatic process GO:0042592 331 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
apoptotic process GO:0006915 381 0.020
secretion by cell GO:0032940 248 0.020
purine containing compound metabolic process GO:0072521 253 0.020
regulation of protein modification process GO:0031399 194 0.020
regulation of canonical wnt signaling pathway GO:0060828 4 0.020
ras protein signal transduction GO:0007265 29 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
regulation of programmed cell death GO:0043067 341 0.019
localization of cell GO:0051674 202 0.019
head development GO:0060322 247 0.019
response to carbohydrate GO:0009743 183 0.019
intracellular signal transduction GO:0035556 314 0.018
locomotion GO:0040011 237 0.018
central nervous system development GO:0007417 311 0.018
response to growth factor GO:0070848 189 0.018
cellular response to stress GO:0033554 269 0.018
regulation of cell migration GO:0030334 128 0.018
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.018
cellular component morphogenesis GO:0032989 155 0.017
reproductive process GO:0022414 372 0.017
tissue development GO:0009888 252 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
neuron development GO:0048666 286 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
cell projection morphogenesis GO:0048858 123 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
positive regulation of response to stimulus GO:0048584 285 0.016
peptidyl amino acid modification GO:0018193 126 0.016
growth GO:0040007 165 0.016
response to biotic stimulus GO:0009607 226 0.016
establishment of protein localization GO:0045184 141 0.016
eye morphogenesis GO:0048592 4 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
regulation of cell proliferation GO:0042127 359 0.015
response to other organism GO:0051707 220 0.015
response to nutrient levels GO:0031667 370 0.015
secretion GO:0046903 307 0.015
embryonic pattern specification GO:0009880 1 0.015
brain development GO:0007420 247 0.015
regulation of cellular component movement GO:0051270 150 0.015
response to bacterium GO:0009617 200 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
positive regulation of dendrite development GO:1900006 35 0.014
dendrite morphogenesis GO:0048813 43 0.014
axis specification GO:0009798 4 0.014
oxoacid metabolic process GO:0043436 290 0.014
multicellular organism reproduction GO:0032504 233 0.014
cardiovascular system development GO:0072358 134 0.014
regulation of dendrite morphogenesis GO:0048814 33 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
reproduction GO:0000003 245 0.014
bmp signaling pathway GO:0030509 4 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
tube development GO:0035295 89 0.013
multi organism reproductive process GO:0044703 262 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
proteolysis GO:0006508 175 0.013
salivary gland development GO:0007431 3 0.013
neuron death GO:0070997 127 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
axon development GO:0061564 96 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
response to metal ion GO:0010038 253 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.013
positive regulation of dendrite morphogenesis GO:0050775 21 0.013
chromatin organization GO:0006325 34 0.013
cellular macromolecule localization GO:0070727 122 0.012
cellular chemical homeostasis GO:0055082 247 0.012
protein complex assembly GO:0006461 263 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
cellular homeostasis GO:0019725 252 0.012
chemical homeostasis GO:0048878 292 0.012
response to external biotic stimulus GO:0043207 221 0.012
chromatin assembly or disassembly GO:0006333 1 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
nucleosome organization GO:0034728 1 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
response to oxygen levels GO:0070482 265 0.012
heterocycle catabolic process GO:0046700 167 0.012
regulation of system process GO:0044057 208 0.011
response to estradiol GO:0032355 164 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
embryonic skeletal system development GO:0048706 3 0.011
covalent chromatin modification GO:0016569 30 0.011
regulation of synaptic transmission GO:0050804 141 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
cell morphogenesis GO:0000902 142 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
response to cytokine GO:0034097 215 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
cellular response to lipid GO:0071396 201 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
catabolic process GO:0009056 351 0.011
dna metabolic process GO:0006259 96 0.011
learning or memory GO:0007611 90 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
cellular catabolic process GO:0044248 295 0.011
response to estrogen GO:0043627 232 0.010
purine ribonucleotide biosynthetic process GO:0009152 81 0.010
histone modification GO:0016570 30 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010
regulation of signal transduction GO:0009966 318 0.010
synaptic transmission GO:0007268 235 0.010
macromolecular complex assembly GO:0065003 273 0.010
organ formation GO:0048645 3 0.010
regulation of molecular function GO:0065009 398 0.010
cation homeostasis GO:0055080 195 0.010
chromatin remodeling GO:0006338 3 0.010
aging GO:0007568 241 0.010
positive regulation of molecular function GO:0044093 230 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
regulation of locomotion GO:0040012 148 0.010

Numa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.014
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
cardiovascular system disease DOID:1287 0 0.013