Rattus norvegicus

0 known processes

Lrp10

low-density lipoprotein receptor-related protein 10

(Aliases: MGC124814)

Lrp10 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.266
positive regulation of jnk cascade GO:0046330 13 0.253
peptide biosynthetic process GO:0043043 3 0.219
store operated calcium entry GO:0002115 2 0.164
positive regulation of response to stimulus GO:0048584 285 0.094
response to metal ion GO:0010038 253 0.084
regulation of cellular localization GO:0060341 263 0.077
protein heterooligomerization GO:0051291 89 0.075
positive regulation of i kappab kinase nf kappab signaling GO:0043123 8 0.070
apoptotic process GO:0006915 381 0.067
positive regulation of protein transport GO:0051222 41 0.061
macromolecule localization GO:0033036 252 0.059
Mouse
positive regulation of cell communication GO:0010647 271 0.056
response to tumor necrosis factor GO:0034612 56 0.049
protein phosphorylation GO:0006468 345 0.049
establishment of protein localization GO:0045184 141 0.048
intracellular signal transduction GO:0035556 314 0.047
positive regulation of cell death GO:0010942 184 0.045
negative regulation of odontogenesis of dentin containing tooth GO:0042489 1 0.044
locomotion GO:0040011 237 0.043
regulation of signal transduction GO:0009966 318 0.043
positive regulation of neuron death GO:1901216 43 0.042
cellular response to tumor necrosis factor GO:0071356 46 0.042
response to growth factor GO:0070848 189 0.042
cellular response to nitrogen compound GO:1901699 210 0.041
cellular response to endogenous stimulus GO:0071495 377 0.041
macromolecular complex subunit organization GO:0043933 339 0.041
regulation of response to stress GO:0080134 126 0.041
cellular response to hormone stimulus GO:0032870 247 0.041
regulation of apoptotic process GO:0042981 335 0.040
protein complex assembly GO:0006461 263 0.040
cellular component movement GO:0006928 248 0.040
organic substance catabolic process GO:1901575 316 0.039
protein oligomerization GO:0051259 191 0.038
organonitrogen compound biosynthetic process GO:1901566 167 0.038
positive regulation of intracellular signal transduction GO:1902533 138 0.037
carbohydrate derivative biosynthetic process GO:1901137 124 0.037
nucleotide metabolic process GO:0009117 279 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.036
cellular chemical homeostasis GO:0055082 247 0.034
oxoacid metabolic process GO:0043436 290 0.034
positive regulation of biosynthetic process GO:0009891 319 0.034
cellular response to abiotic stimulus GO:0071214 85 0.033
cellular component assembly GO:0022607 360 0.033
programmed cell death GO:0012501 392 0.032
response to acid chemical GO:0001101 222 0.032
chemical homeostasis GO:0048878 292 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
positive regulation of phosphate metabolic process GO:0045937 262 0.032
cell projection organization GO:0030030 302 0.032
homeostatic process GO:0042592 331 0.032
response to mechanical stimulus GO:0009612 134 0.032
extrinsic apoptotic signaling pathway GO:0097191 10 0.031
negative regulation of bone resorption GO:0045779 5 0.031
carbohydrate derivative catabolic process GO:1901136 147 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
response to magnesium ion GO:0032026 20 0.030
cytokine mediated signaling pathway GO:0019221 43 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.030
positive regulation of signaling GO:0023056 270 0.029
response to peptide hormone GO:0043434 278 0.029
ribose phosphate metabolic process GO:0019693 235 0.028
response to hypoxia GO:0001666 231 0.028
defense response to other organism GO:0098542 17 0.028
cellular response to external stimulus GO:0071496 118 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
liver development GO:0001889 90 0.027
single organism biosynthetic process GO:0044711 342 0.027
cellular response to organonitrogen compound GO:0071417 197 0.027
single organism membrane organization GO:0044802 74 0.026
response to lipopolysaccharide GO:0032496 191 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
cellular response to mechanical stimulus GO:0071260 48 0.026
reproductive process GO:0022414 372 0.026
reproduction GO:0000003 245 0.026
immune system process GO:0002376 204 0.025
hepaticobiliary system development GO:0061008 90 0.025
cellular homeostasis GO:0019725 252 0.025
protein transport GO:0015031 132 0.025
aging GO:0007568 241 0.024
regulation of phosphorylation GO:0042325 248 0.024
catabolic process GO:0009056 351 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
bone remodeling GO:0046849 23 0.024
gland development GO:0048732 155 0.024
positive regulation of tyrosine phosphorylation of stat1 protein GO:0042511 1 0.024
positive regulation of cell projection organization GO:0031346 111 0.023
positive regulation of developmental process GO:0051094 283 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
secretion by cell GO:0032940 248 0.023
cellular response to cytokine stimulus GO:0071345 127 0.023
regulation of jnk cascade GO:0046328 19 0.022
response to estrogen GO:0043627 232 0.022
ion homeostasis GO:0050801 212 0.022
negative regulation of odontogenesis GO:0042483 1 0.022
multicellular organismal homeostasis GO:0048871 49 0.022
response to peptide GO:1901652 292 0.022
localization of cell GO:0051674 202 0.021
protein complex biogenesis GO:0070271 263 0.021
cellular macromolecule localization GO:0070727 122 0.021
cation transport GO:0006812 382 0.020
purine containing compound metabolic process GO:0072521 253 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
negative regulation of metabolic process GO:0009892 331 0.020
cellular amide metabolic process GO:0043603 44 0.020
response to alkaloid GO:0043279 132 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.019
response to cytokine GO:0034097 215 0.019
cell motility GO:0048870 202 0.019
macromolecular complex assembly GO:0065003 273 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 7 0.019
negative regulation of innate immune response GO:0045824 4 0.019
regulation of mapk cascade GO:0043408 116 0.019
regulation of locomotion GO:0040012 148 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
negative regulation of signaling GO:0023057 157 0.018
secretion GO:0046903 307 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
development of primary female sexual characteristics GO:0046545 56 0.017
purine containing compound catabolic process GO:0072523 138 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
positive regulation of signal transduction GO:0009967 175 0.017
response to hydrogen peroxide GO:0042542 89 0.017
negative regulation of rna splicing GO:0033119 3 0.017
protein import GO:0017038 37 0.017
anatomical structure homeostasis GO:0060249 29 0.017
transmembrane transport GO:0055085 412 0.017
cation homeostasis GO:0055080 195 0.017
lipid biosynthetic process GO:0008610 128 0.016
craniofacial suture morphogenesis GO:0097094 4 0.016
tissue homeostasis GO:0001894 28 0.016
blood circulation GO:0008015 183 0.015
regulation of immune system process GO:0002682 123 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
response to nutrient GO:0007584 248 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
cellular catabolic process GO:0044248 295 0.015
anion transport GO:0006820 178 0.015
single fertilization GO:0007338 3 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
regulation of membrane potential GO:0042391 110 0.014
regulation of odontogenesis GO:0042481 4 0.014
gliogenesis GO:0042063 93 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
tissue remodeling GO:0048771 40 0.014
positive regulation of molecular function GO:0044093 230 0.014
protein localization GO:0008104 191 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
establishment of tissue polarity GO:0007164 2 0.014
regulation of catalytic activity GO:0050790 304 0.014
amine metabolic process GO:0009308 38 0.014
regulation of cell proliferation GO:0042127 359 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
metal ion homeostasis GO:0055065 186 0.013
cation transmembrane transport GO:0098655 263 0.013
protein targeting GO:0006605 61 0.013
response to fluoride GO:1902617 3 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
negative regulation of cell death GO:0060548 229 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
regulation of protein metabolic process GO:0051246 289 0.013
multi organism reproductive process GO:0044703 262 0.013
innate immune response GO:0045087 35 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
single organism behavior GO:0044708 130 0.013
positive regulation of intracellular protein transport GO:0090316 20 0.013
regulation of molecular function GO:0065009 398 0.013
cellular response to oxygen containing compound GO:1901701 386 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
single organism cellular localization GO:1902580 102 0.013
regulation of protein transport GO:0051223 68 0.013
hematopoietic or lymphoid organ development GO:0048534 36 0.013
intracellular protein transport GO:0006886 79 0.012
single organism intracellular transport GO:1902582 166 0.012
regulation of programmed cell death GO:0043067 341 0.012
organic acid metabolic process GO:0006082 292 0.012
regulation of hormone levels GO:0010817 187 0.012
head development GO:0060322 247 0.012
circulatory system process GO:0003013 183 0.012
regulation of transcription dna templated GO:0006355 374 0.012
nucleotide catabolic process GO:0009166 139 0.012
meiotic cell cycle process GO:1903046 3 0.012
response to transforming growth factor beta GO:0071559 46 0.012
response to oxidative stress GO:0006979 186 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
negative regulation of transport GO:0051051 136 0.011
defense response to gram positive bacterium GO:0050830 2 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
response to inorganic substance GO:0010035 377 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
positive regulation of cytoplasmic transport GO:1903651 32 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
cellular cation homeostasis GO:0030003 180 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
protein complex subunit organization GO:0071822 302 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
response to ammonium ion GO:0060359 71 0.011
regulation of homeostatic process GO:0032844 101 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
cellular lipid metabolic process GO:0044255 208 0.010
cellular amine metabolic process GO:0044106 38 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
actin filament branching GO:0090135 1 0.010
gtp catabolic process GO:0006184 71 0.010
positive regulation of transport GO:0051050 245 0.010
glycosyl compound metabolic process GO:1901657 182 0.010

Lrp10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.071
nervous system disease DOID:863 0 0.071
cardiovascular system disease DOID:1287 0 0.069
muscular disease DOID:0080000 0 0.067
musculoskeletal system disease DOID:17 0 0.067
muscle tissue disease DOID:66 0 0.067
nephritis DOID:10952 0 0.060
glomerulonephritis DOID:2921 0 0.060
kidney disease DOID:557 0 0.060
urinary system disease DOID:18 0 0.060
central nervous system disease DOID:331 0 0.028
myopathy DOID:423 0 0.026
heart disease DOID:114 0 0.026
cardiomyopathy DOID:0050700 0 0.026
dilated cardiomyopathy DOID:12930 0 0.026
intrinsic cardiomyopathy DOID:0060036 0 0.026
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
lipodystrophy DOID:811 0 0.017
skin disease DOID:37 0 0.017
integumentary system disease DOID:16 0 0.017
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.014
lipid storage disease DOID:9455 0 0.011
lysosomal storage disease DOID:3211 0 0.011