Rattus norvegicus

20 known processes

Hemgn

hemogen

(Aliases: Hgn,Edag1,RP59,Edag-1)

Hemgn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of multicellular organismal process GO:0051240 387 0.195
protein heterooligomerization GO:0051291 89 0.190
oxoacid metabolic process GO:0043436 290 0.160
regulation of multicellular organismal development GO:2000026 376 0.130
organic acid metabolic process GO:0006082 292 0.124
positive regulation of cell proliferation GO:0008284 249 0.107
cation transport GO:0006812 382 0.106
positive regulation of biosynthetic process GO:0009891 319 0.101
negative regulation of multicellular organismal process GO:0051241 203 0.099
cation homeostasis GO:0055080 195 0.087
carboxylic acid metabolic process GO:0019752 289 0.084
homeostatic process GO:0042592 331 0.083
single organism reproductive process GO:0044702 297 0.080
regulation of cellular protein metabolic process GO:0032268 267 0.080
negative regulation of cell death GO:0060548 229 0.079
positive regulation of phosphorus metabolic process GO:0010562 262 0.078
nitrogen compound transport GO:0071705 229 0.075
regulation of protein metabolic process GO:0051246 289 0.075
regulation of system process GO:0044057 208 0.074
regulation of programmed cell death GO:0043067 341 0.073
amine metabolic process GO:0009308 38 0.073
regulation of cellular localization GO:0060341 263 0.071
neuron differentiation GO:0030182 368 0.071
positive regulation of phosphate metabolic process GO:0045937 262 0.071
cellular response to lipid GO:0071396 201 0.069
growth GO:0040007 165 0.066
inorganic ion transmembrane transport GO:0098660 229 0.066
cellular response to endogenous stimulus GO:0071495 377 0.066
response to inorganic substance GO:0010035 377 0.062
regulation of transcription dna templated GO:0006355 374 0.061
regulation of homeostatic process GO:0032844 101 0.059
multicellular organismal homeostasis GO:0048871 49 0.059
positive regulation of protein modification process GO:0031401 142 0.058
regulation of cell differentiation GO:0045595 320 0.057
protein oligomerization GO:0051259 191 0.055
response to cytokine GO:0034097 215 0.054
positive regulation of developmental process GO:0051094 283 0.054
positive regulation of phosphorylation GO:0042327 177 0.052
organic acid transport GO:0015849 116 0.052
regulation of phosphate metabolic process GO:0019220 349 0.052
regulation of cellular component organization GO:0051128 368 0.052
response to oxygen levels GO:0070482 265 0.052
reproductive process GO:0022414 372 0.051
regulation of muscle system process GO:0090257 79 0.051
protein complex assembly GO:0006461 263 0.050
anion transmembrane transport GO:0098656 77 0.049
regulation of apoptotic process GO:0042981 335 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.049
nucleoside phosphate metabolic process GO:0006753 283 0.048
negative regulation of metabolic process GO:0009892 331 0.047
developmental process involved in reproduction GO:0003006 159 0.046
positive regulation of molecular function GO:0044093 230 0.046
synaptic transmission GO:0007268 235 0.046
positive regulation of signaling GO:0023056 270 0.046
cellular amino acid metabolic process GO:0006520 107 0.046
rna metabolic process GO:0016070 406 0.046
multicellular organism reproduction GO:0032504 233 0.046
regulation of cell projection size GO:0032536 1 0.045
ion transmembrane transport GO:0034220 365 0.045
ion homeostasis GO:0050801 212 0.045
positive regulation of cell communication GO:0010647 271 0.044
proteolysis GO:0006508 175 0.044
programmed cell death GO:0012501 392 0.043
cellular divalent inorganic cation homeostasis GO:0072503 162 0.042
cellular component morphogenesis GO:0032989 155 0.041
cell migration GO:0016477 197 0.040
cellular amine metabolic process GO:0044106 38 0.040
nucleobase containing small molecule metabolic process GO:0055086 316 0.039
response to biotic stimulus GO:0009607 226 0.039
defense response GO:0006952 194 0.039
head development GO:0060322 247 0.039
cellular ketone metabolic process GO:0042180 51 0.039
regulation of catalytic activity GO:0050790 304 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
response to nutrient levels GO:0031667 370 0.039
muscle system process GO:0003012 115 0.038
chemical homeostasis GO:0048878 292 0.038
regulation of body fluid levels GO:0050878 90 0.038
regulation of organic acid transport GO:0032890 35 0.038
regulation of ossification GO:0030278 32 0.037
macromolecular complex assembly GO:0065003 273 0.037
metal ion homeostasis GO:0055065 186 0.037
blood vessel development GO:0001568 69 0.037
cellular response to growth factor stimulus GO:0071363 162 0.036
cellular response to oxygen containing compound GO:1901701 386 0.036
cellular ion homeostasis GO:0006873 184 0.036
cellular lipid metabolic process GO:0044255 208 0.035
organic anion transport GO:0015711 132 0.035
positive regulation of protein phosphorylation GO:0001934 135 0.034
cellular response to stress GO:0033554 269 0.034
response to wounding GO:0009611 254 0.034
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
anatomical structure morphogenesis GO:0009653 298 0.033
response to other organism GO:0051707 220 0.033
metal ion transport GO:0030001 289 0.032
cell morphogenesis GO:0000902 142 0.032
aging GO:0007568 241 0.032
response to external biotic stimulus GO:0043207 221 0.032
cell projection organization GO:0030030 302 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
response to decreased oxygen levels GO:0036293 237 0.031
intracellular signal transduction GO:0035556 314 0.031
negative regulation of gene expression GO:0010629 199 0.031
antibiotic transport GO:0042891 2 0.030
cofactor metabolic process GO:0051186 95 0.030
cellular chemical homeostasis GO:0055082 247 0.029
cellular component assembly GO:0022607 360 0.029
regulation of neuron death GO:1901214 115 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
regulation of anatomical structure morphogenesis GO:0022603 141 0.029
heterocycle catabolic process GO:0046700 167 0.029
urogenital system development GO:0001655 78 0.029
cellular homeostasis GO:0019725 252 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
response to mechanical stimulus GO:0009612 134 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
response to transition metal nanoparticle GO:1990267 122 0.028
regulation of molecular function GO:0065009 398 0.028
regulation of cell proliferation GO:0042127 359 0.028
regulation of cellular component movement GO:0051270 150 0.027
secretion GO:0046903 307 0.027
regulation of response to wounding GO:1903034 69 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
reproduction GO:0000003 245 0.027
single organism biosynthetic process GO:0044711 342 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
positive regulation of ion transport GO:0043270 94 0.026
positive regulation of synaptic transmission GO:0050806 62 0.026
response to radiation GO:0009314 137 0.026
neurological system process GO:0050877 219 0.026
carboxylic acid transport GO:0046942 115 0.026
inorganic cation transmembrane transport GO:0098662 202 0.025
reproductive system development GO:0061458 128 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
localization of cell GO:0051674 202 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
male sex differentiation GO:0046661 64 0.025
immune response GO:0006955 104 0.025
gonad development GO:0008406 104 0.024
metestrus GO:0060210 1 0.024
blood circulation GO:0008015 183 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
nucleotide metabolic process GO:0009117 279 0.024
anatomical structure homeostasis GO:0060249 29 0.024
response to testosterone GO:0033574 55 0.024
apoptotic process GO:0006915 381 0.024
cell growth GO:0016049 104 0.024
skeletal muscle tissue development GO:0007519 31 0.024
potassium ion transmembrane transport GO:0071805 71 0.024
protein complex biogenesis GO:0070271 263 0.024
cellular cation homeostasis GO:0030003 180 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
vesicle mediated transport GO:0016192 181 0.024
cellular response to nitrogen compound GO:1901699 210 0.023
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
regulation of blood circulation GO:1903522 110 0.023
response to ethanol GO:0045471 162 0.023
regulation of cell development GO:0060284 263 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
purine containing compound metabolic process GO:0072521 253 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.023
regulation of cell activation GO:0050865 50 0.023
positive regulation of signal transduction GO:0009967 175 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
response to peptide GO:1901652 292 0.022
response to peptide hormone GO:0043434 278 0.022
response to hypoxia GO:0001666 231 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
signal transduction by phosphorylation GO:0023014 144 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
cell adhesion GO:0007155 110 0.022
lipid metabolic process GO:0006629 283 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.021
organophosphate metabolic process GO:0019637 370 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
regulation of response to stress GO:0080134 126 0.021
circulatory system development GO:0072359 134 0.021
regulation of hormone levels GO:0010817 187 0.021
protein maturation GO:0051604 68 0.021
multi organism reproductive process GO:0044703 262 0.021
cellular response to oxidative stress GO:0034599 76 0.021
cell activation GO:0001775 97 0.021
cellular component movement GO:0006928 248 0.021
positive regulation of cell projection organization GO:0031346 111 0.021
regulation of phosphorylation GO:0042325 248 0.021
regulation of hydrolase activity GO:0051336 143 0.020
response to bacterium GO:0009617 200 0.020
positive regulation of protein kinase activity GO:0045860 73 0.020
neuron projection development GO:0031175 273 0.020
neuron development GO:0048666 286 0.020
monovalent inorganic cation transport GO:0015672 172 0.019
response to purine containing compound GO:0014074 126 0.019
regulation of rna metabolic process GO:0051252 391 0.019
gland development GO:0048732 155 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
transcription dna templated GO:0006351 377 0.019
erk1 and erk2 cascade GO:0070371 48 0.019
positive regulation of map kinase activity GO:0043406 46 0.019
response to extracellular stimulus GO:0009991 380 0.019
fatty acid biosynthetic process GO:0006633 33 0.019
dephosphorylation GO:0016311 98 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
amine transport GO:0015837 57 0.019
cell cell signaling GO:0007267 335 0.018
regulation of neuron apoptotic process GO:0043523 83 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
sexual reproduction GO:0019953 148 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
carboxylic acid biosynthetic process GO:0046394 83 0.018
defense response to other organism GO:0098542 17 0.018
regulation of ion transport GO:0043269 245 0.018
regulation of immune system process GO:0002682 123 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.018
regulation of cell projection organization GO:0031344 175 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
circulatory system process GO:0003013 183 0.018
regulation of synaptic transmission GO:0050804 141 0.018
reproductive structure development GO:0048608 128 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
cofactor biosynthetic process GO:0051188 28 0.018
response to oxidative stress GO:0006979 186 0.018
gamete generation GO:0007276 124 0.018
rna biosynthetic process GO:0032774 380 0.017
sex differentiation GO:0007548 113 0.017
cardiovascular system development GO:0072358 134 0.017
regulation of cell migration GO:0030334 128 0.017
development of primary sexual characteristics GO:0045137 107 0.017
biological adhesion GO:0022610 110 0.017
positive regulation of gene expression GO:0010628 244 0.017
leukocyte cell cell adhesion GO:0007159 4 0.017
learning or memory GO:0007611 90 0.017
catabolic process GO:0009056 351 0.017
regulation of locomotion GO:0040012 148 0.017
cell motility GO:0048870 202 0.017
response to growth factor GO:0070848 189 0.017
mapk cascade GO:0000165 140 0.017
positive regulation of nervous system development GO:0051962 178 0.016
anion transport GO:0006820 178 0.016
kidney development GO:0001822 67 0.016
acid secretion GO:0046717 48 0.015
regulation of protein modification process GO:0031399 194 0.015
regulation of muscle contraction GO:0006937 53 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
response to interleukin 13 GO:0035962 3 0.015
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.015
positive regulation of cell activation GO:0050867 34 0.015
regulation of blood pressure GO:0008217 83 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
amino acid transport GO:0006865 70 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
anterior posterior pattern specification GO:0009952 1 0.015
response to organophosphorus GO:0046683 102 0.015
organelle organization GO:0006996 266 0.015
regulation of cell motility GO:2000145 131 0.015
regulation of neurogenesis GO:0050767 247 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.014
tube development GO:0035295 89 0.014
regulation of secretion GO:0051046 224 0.014
neuron death GO:0070997 127 0.014
chloride transmembrane transport GO:1902476 24 0.014
regulation of cell cycle GO:0051726 73 0.014
potassium ion transport GO:0006813 97 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
embryonic pattern specification GO:0009880 1 0.014
immune system process GO:0002376 204 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
female sex differentiation GO:0046660 59 0.014
regulation of signal transduction GO:0009966 318 0.014
positive regulation of secretion GO:0051047 140 0.014
protein phosphorylation GO:0006468 345 0.014
regulation of heterotypic cell cell adhesion GO:0034114 2 0.014
small molecule catabolic process GO:0044282 59 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of cell development GO:0010720 176 0.014
calcium ion homeostasis GO:0055074 162 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
negative regulation of protein maturation GO:1903318 47 0.013
brain development GO:0007420 247 0.013
small molecule biosynthetic process GO:0044283 124 0.013
protein processing GO:0016485 68 0.013
muscle contraction GO:0006936 88 0.013
negative regulation of transport GO:0051051 136 0.013
nucleoside metabolic process GO:0009116 179 0.013
regulation of proteolysis GO:0030162 66 0.013
response to estrogen GO:0043627 232 0.013
regulation of protein maturation GO:1903317 50 0.013
hematopoietic progenitor cell differentiation GO:0002244 2 0.013
hepaticobiliary system development GO:0061008 90 0.013
spermatogenesis GO:0007283 99 0.013
male gonad development GO:0008584 59 0.013
regulation of protein processing GO:0070613 50 0.013
epithelial cell differentiation GO:0030855 71 0.013
positive regulation of epithelial cell migration GO:0010634 13 0.012
regulation of endocytosis GO:0030100 42 0.012
cellular response to fluid shear stress GO:0071498 4 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
developmental growth GO:0048589 100 0.012
response to alkaloid GO:0043279 132 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
axis specification GO:0009798 4 0.012
rhythmic process GO:0048511 156 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of isotype switching GO:0045830 1 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
hormone metabolic process GO:0042445 69 0.012
organic substance catabolic process GO:1901575 316 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
nucleoside catabolic process GO:0009164 126 0.012
response to tumor necrosis factor GO:0034612 56 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
protein modification by small protein conjugation or removal GO:0070647 35 0.012
erythrocyte homeostasis GO:0034101 2 0.012
response to zinc ion GO:0010043 39 0.012
cell type specific apoptotic process GO:0097285 134 0.012
somatic diversification of immunoglobulins involved in immune response GO:0002208 1 0.012
response to muscle stretch GO:0035994 2 0.012
coenzyme metabolic process GO:0006732 86 0.012
nucleic acid templated transcription GO:0097659 379 0.012
positive regulation of stress activated mapk cascade GO:0032874 17 0.012
regulation of embryonic development GO:0045995 2 0.012
regulation of membrane potential GO:0042391 110 0.012
regulation of b cell differentiation GO:0045577 1 0.012
liver development GO:0001889 90 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of anion transport GO:0044070 43 0.011
regulation of mapk cascade GO:0043408 116 0.011
positive regulation of cell migration GO:0030335 96 0.011
vasculature development GO:0001944 70 0.011
regulation of defense response GO:0031347 68 0.011
regulation of jun kinase activity GO:0043506 10 0.011
negative regulation of ion transport GO:0043271 51 0.011
dna integrity checkpoint GO:0031570 2 0.011
memory GO:0007613 54 0.011
embryonic axis specification GO:0000578 1 0.011
heart contraction GO:0060047 57 0.011
regulation of epithelial cell proliferation GO:0050678 49 0.011
protein complex subunit organization GO:0071822 302 0.011
leukocyte activation GO:0045321 76 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
negative regulation of biomineral tissue development GO:0070168 2 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
regulation of cellular response to stress GO:0080135 49 0.011
positive regulation of growth GO:0045927 55 0.010
cellular response to molecule of bacterial origin GO:0071219 56 0.010
regulation of anatomical structure size GO:0090066 135 0.010
response to hyperoxia GO:0055093 45 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
tissue homeostasis GO:0001894 28 0.010
platelet aggregation GO:0070527 4 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
male gamete generation GO:0048232 99 0.010
defense response to fungus GO:0050832 1 0.010
regulation of immune response GO:0050776 55 0.010
organic acid biosynthetic process GO:0016053 83 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
regulation of peptidase activity GO:0052547 55 0.010
striated muscle contraction GO:0006941 44 0.010
organic hydroxy compound transport GO:0015850 77 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
synaptic vesicle transport GO:0048489 23 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
regulation of behavior GO:0050795 61 0.010
tissue regeneration GO:0042246 36 0.010
circadian rhythm GO:0007623 88 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
positive regulation of transport GO:0051050 245 0.010
positive regulation of leukocyte activation GO:0002696 30 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010

Hemgn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016