Rattus norvegicus

167 known processes

Ak1

adenylate kinase 1

(Aliases: MGC108678)

Ak1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.192
single organism carbohydrate metabolic process GO:0044723 118 0.163
cellular carbohydrate metabolic process GO:0044262 72 0.163
carbohydrate metabolic process GO:0005975 130 0.163
energy derivation by oxidation of organic compounds GO:0015980 46 0.163
positive regulation of transport GO:0051050 245 0.147
organophosphate metabolic process GO:0019637 370 0.133
organic substance catabolic process GO:1901575 316 0.122
generation of precursor metabolites and energy GO:0006091 62 0.121
homeostatic process GO:0042592 331 0.114
response to monosaccharide GO:0034284 159 0.111
monosaccharide metabolic process GO:0005996 61 0.106
carboxylic acid metabolic process GO:0019752 289 0.101
protein complex biogenesis GO:0070271 263 0.100
organic acid metabolic process GO:0006082 292 0.096
cellular component assembly GO:0022607 360 0.096
apoptotic process GO:0006915 381 0.093
catabolic process GO:0009056 351 0.089
regulation of secretion GO:0051046 224 0.084
regulation of ion transport GO:0043269 245 0.081
single organism biosynthetic process GO:0044711 342 0.079
glycogen metabolic process GO:0005977 23 0.078
macromolecular complex subunit organization GO:0043933 339 0.076
neuron development GO:0048666 286 0.073
secretion GO:0046903 307 0.072
cell cell signaling GO:0007267 335 0.071
regulation of rna biosynthetic process GO:2001141 381 0.071
cellular response to oxygen containing compound GO:1901701 386 0.071
cellular component biogenesis GO:0044085 368 0.069
cation transport GO:0006812 382 0.069
response to glucose GO:0009749 136 0.068
regulation of cellular component organization GO:0051128 368 0.067
monocarboxylic acid metabolic process GO:0032787 152 0.067
cellular glucan metabolic process GO:0006073 23 0.066
cellular component morphogenesis GO:0032989 155 0.063
behavior GO:0007610 205 0.061
regulation of rna metabolic process GO:0051252 391 0.059
neuron differentiation GO:0030182 368 0.059
cellular lipid metabolic process GO:0044255 208 0.059
neurological system process GO:0050877 219 0.059
multi organism reproductive process GO:0044703 262 0.057
carbohydrate derivative metabolic process GO:1901135 346 0.056
oxidation reduction process GO:0055114 304 0.055
glucose metabolic process GO:0006006 52 0.054
carbohydrate catabolic process GO:0016052 40 0.053
secretion by cell GO:0032940 248 0.052
transmembrane transport GO:0055085 412 0.050
glucan metabolic process GO:0044042 23 0.050
macromolecular complex assembly GO:0065003 273 0.049
positive regulation of multicellular organismal process GO:0051240 387 0.048
single organism catabolic process GO:0044712 283 0.048
pyruvate metabolic process GO:0006090 27 0.046
transcription dna templated GO:0006351 377 0.046
synaptic transmission cholinergic GO:0007271 11 0.046
metal ion transport GO:0030001 289 0.046
signal release GO:0023061 145 0.046
response to hexose GO:0009746 144 0.044
cellular homeostasis GO:0019725 252 0.044
cellular chemical homeostasis GO:0055082 247 0.044
regulation of vesicle mediated transport GO:0060627 81 0.043
regulation of metal ion transport GO:0010959 118 0.042
synaptic transmission GO:0007268 235 0.042
protein autophosphorylation GO:0046777 66 0.042
energy reserve metabolic process GO:0006112 25 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
peptidyl threonine modification GO:0018210 7 0.042
nucleic acid templated transcription GO:0097659 379 0.041
regulation of secretion by cell GO:1903530 208 0.040
response to carbohydrate GO:0009743 183 0.040
single organism behavior GO:0044708 130 0.040
response to temperature stimulus GO:0009266 94 0.039
action potential GO:0001508 54 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.038
regulation of hormone secretion GO:0046883 106 0.038
cellular catabolic process GO:0044248 295 0.038
regulation of hydrolase activity GO:0051336 143 0.037
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.037
chemical homeostasis GO:0048878 292 0.037
protein complex subunit organization GO:0071822 302 0.037
reproduction GO:0000003 245 0.037
myelination GO:0042552 39 0.037
establishment of organelle localization GO:0051656 37 0.036
cell projection organization GO:0030030 302 0.036
fatty acid metabolic process GO:0006631 99 0.035
inorganic cation transmembrane transport GO:0098662 202 0.035
intracellular signal transduction GO:0035556 314 0.035
rna biosynthetic process GO:0032774 380 0.034
reproductive process GO:0022414 372 0.034
regulation of cellular localization GO:0060341 263 0.034
positive regulation of atpase activity GO:0032781 6 0.033
regulation of growth GO:0040008 105 0.033
microtubule cytoskeleton organization GO:0000226 25 0.033
hormone transport GO:0009914 121 0.033
cation transmembrane transport GO:0098655 263 0.033
glucose homeostasis GO:0042593 75 0.032
cellular polysaccharide metabolic process GO:0044264 23 0.032
regulation of ryanodine sensitive calcium release channel activity GO:0060314 5 0.032
regulation of ion transmembrane transporter activity GO:0032412 48 0.032
regulation of transmembrane transport GO:0034762 122 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
programmed cell death GO:0012501 392 0.031
response to nutrient GO:0007584 248 0.031
response to ketone GO:1901654 182 0.030
carbohydrate homeostasis GO:0033500 75 0.030
regulation of programmed cell death GO:0043067 341 0.029
neuron projection development GO:0031175 273 0.029
hexose biosynthetic process GO:0019319 15 0.029
axis specification GO:0009798 4 0.029
response to mineralocorticoid GO:0051385 49 0.029
multi multicellular organism process GO:0044706 138 0.029
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
calcium ion transport GO:0006816 131 0.028
regulation of system process GO:0044057 208 0.027
lipid metabolic process GO:0006629 283 0.027
cellular response to stress GO:0033554 269 0.027
hexose metabolic process GO:0019318 58 0.027
positive regulation of developmental process GO:0051094 283 0.027
chemosensory behavior GO:0007635 2 0.027
regulation of cell development GO:0060284 263 0.026
sexual reproduction GO:0019953 148 0.026
cellular calcium ion homeostasis GO:0006874 160 0.026
heterocycle catabolic process GO:0046700 167 0.026
regulation of cell maturation GO:1903429 3 0.026
positive regulation of secretion GO:0051047 140 0.026
divalent inorganic cation transport GO:0072511 134 0.026
regulation of camp metabolic process GO:0030814 43 0.025
single organism cellular localization GO:1902580 102 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
protein phosphorylation GO:0006468 345 0.025
peptide secretion GO:0002790 86 0.025
regulation of peptide transport GO:0090087 87 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
amide transport GO:0042886 105 0.024
regulation of nucleotide metabolic process GO:0006140 117 0.024
regulation of protein metabolic process GO:0051246 289 0.023
cellular response to external stimulus GO:0071496 118 0.023
cell projection morphogenesis GO:0048858 123 0.023
aromatic compound catabolic process GO:0019439 168 0.023
carbohydrate derivative biosynthetic process GO:1901137 124 0.023
nitrogen compound transport GO:0071705 229 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
organophosphate biosynthetic process GO:0090407 143 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
polysaccharide metabolic process GO:0005976 25 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
transmission of nerve impulse GO:0019226 42 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
regulation of anatomical structure size GO:0090066 135 0.022
regulation of gluconeogenesis GO:0006111 4 0.022
protein homooligomerization GO:0051260 91 0.022
rna metabolic process GO:0016070 406 0.022
gluconeogenesis GO:0006094 15 0.022
neuronal action potential GO:0019228 35 0.022
respiratory system process GO:0003016 3 0.022
protein localization GO:0008104 191 0.021
single organism carbohydrate catabolic process GO:0044724 40 0.021
regulation of transcription dna templated GO:0006355 374 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
regulation of synaptic plasticity GO:0048167 70 0.021
positive regulation of cell development GO:0010720 176 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
proteolysis GO:0006508 175 0.021
vesicle organization GO:0016050 29 0.020
response to nutrient levels GO:0031667 370 0.020
reactive nitrogen species metabolic process GO:2001057 1 0.020
exocytosis GO:0006887 60 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
regulation of protein kinase activity GO:0045859 105 0.020
negative regulation of gene expression GO:0010629 199 0.020
cellular response to insulin stimulus GO:0032869 81 0.020
multicellular organismal signaling GO:0035637 44 0.020
single organism reproductive process GO:0044702 297 0.020
multicellular organismal reproductive process GO:0048609 233 0.019
sensory perception GO:0007600 101 0.019
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.019
sodium ion transport GO:0006814 82 0.019
rna localization GO:0006403 4 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
peptidyl amino acid modification GO:0018193 126 0.019
calcium ion homeostasis GO:0055074 162 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.019
ion transmembrane transport GO:0034220 365 0.019
dephosphorylation GO:0016311 98 0.018
regulation of apoptotic process GO:0042981 335 0.018
protein complex assembly GO:0006461 263 0.018
regulation of peptide hormone secretion GO:0090276 80 0.018
positive regulation of molecular function GO:0044093 230 0.018
cellular polysaccharide biosynthetic process GO:0033692 15 0.018
positive regulation of cell death GO:0010942 184 0.018
olfactory behavior GO:0042048 2 0.018
respiratory gaseous exchange GO:0007585 4 0.018
regulation of blood vessel size GO:0050880 89 0.018
regulation of catalytic activity GO:0050790 304 0.017
regulation of organelle organization GO:0033043 80 0.017
hormone secretion GO:0046879 115 0.017
positive regulation of protein export from nucleus GO:0046827 3 0.017
carbohydrate biosynthetic process GO:0016051 42 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
nucleoside metabolic process GO:0009116 179 0.017
cellular ketone metabolic process GO:0042180 51 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
eating behavior GO:0042755 21 0.017
nucleotide metabolic process GO:0009117 279 0.017
regulation of cellular component biogenesis GO:0044087 86 0.017
organelle organization GO:0006996 266 0.016
cellular macromolecule localization GO:0070727 122 0.016
cellular response to peptide GO:1901653 133 0.016
peptide transport GO:0015833 97 0.016
regulation of neurogenesis GO:0050767 247 0.016
peptidyl serine phosphorylation GO:0018105 33 0.016
divalent metal ion transport GO:0070838 132 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
negative regulation of cell communication GO:0010648 158 0.016
glycogen biosynthetic process GO:0005978 15 0.016
establishment of vesicle localization GO:0051650 31 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
establishment of protein localization GO:0045184 141 0.016
synapse organization GO:0050808 46 0.016
regulation of sodium ion transport GO:0002028 21 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.016
positive regulation of catabolic process GO:0009896 78 0.016
growth GO:0040007 165 0.016
gtp metabolic process GO:0046039 72 0.016
regulation of high voltage gated calcium channel activity GO:1901841 3 0.016
regulation of cell differentiation GO:0045595 320 0.015
negative regulation of metabolic process GO:0009892 331 0.015
membrane fusion GO:0061025 26 0.015
embryonic axis specification GO:0000578 1 0.015
negative regulation of signaling GO:0023057 157 0.015
maintenance of location GO:0051235 17 0.015
memory GO:0007613 54 0.015
response to extracellular stimulus GO:0009991 380 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
cation homeostasis GO:0055080 195 0.015
insulin secretion GO:0030073 69 0.015
response to glucocorticoid GO:0051384 223 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
cell cycle GO:0007049 101 0.015
muscle system process GO:0003012 115 0.015
single organism organelle organization GO:1902589 180 0.015
cellular component maintenance GO:0043954 4 0.014
cellular response to carbohydrate stimulus GO:0071322 72 0.014
ion homeostasis GO:0050801 212 0.014
positive regulation of exocytosis GO:0045921 19 0.014
regulation of ion transmembrane transport GO:0034765 121 0.014
response to insecticide GO:0017085 21 0.014
cellular amine metabolic process GO:0044106 38 0.014
cell morphogenesis GO:0000902 142 0.014
cytoplasmic transport GO:0016482 115 0.014
cellular response to hexose stimulus GO:0071331 65 0.014
positive regulation of protein transport GO:0051222 41 0.014
regulation of tight junction assembly GO:2000810 2 0.014
positive regulation of nervous system development GO:0051962 178 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
response to heat GO:0009408 60 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
regulation of protein transport GO:0051223 68 0.014
learning or memory GO:0007611 90 0.014
peptidyl serine modification GO:0018209 34 0.014
cell cycle process GO:0022402 57 0.014
regulation of signal transduction GO:0009966 318 0.014
ras protein signal transduction GO:0007265 29 0.013
positive regulation of monooxygenase activity GO:0032770 5 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
regulation of synaptic transmission GO:0050804 141 0.013
regulation of intracellular transport GO:0032386 65 0.013
neuron projection morphogenesis GO:0048812 122 0.013
regulation of calcium ion transport GO:0051924 77 0.013
response to electrical stimulus GO:0051602 56 0.013
membrane organization GO:0061024 94 0.013
organelle localization GO:0051640 55 0.013
carbohydrate phosphorylation GO:0046835 16 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
wound healing GO:0042060 122 0.013
olfactory learning GO:0008355 1 0.013
ensheathment of neurons GO:0007272 40 0.013
mesoderm morphogenesis GO:0048332 1 0.013
negative regulation of molecular function GO:0044092 133 0.013
response to oxidative stress GO:0006979 186 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
protein oligomerization GO:0051259 191 0.013
regulation of meiotic cell cycle GO:0051445 3 0.013
muscle contraction GO:0006936 88 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.012
cell part morphogenesis GO:0032990 123 0.012
protein transport GO:0015031 132 0.012
multicellular organism reproduction GO:0032504 233 0.012
gamete generation GO:0007276 124 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
aging GO:0007568 241 0.012
regulation of molecular function GO:0065009 398 0.012
regulation of cell cycle g2 m phase transition GO:1902749 4 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
anion transport GO:0006820 178 0.012
embryonic pattern specification GO:0009880 1 0.012
formation of primary germ layer GO:0001704 1 0.012
intracellular transport GO:0046907 185 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of synaptic vesicle exocytosis GO:2000300 6 0.012
response to peptide hormone GO:0043434 278 0.012
heart process GO:0003015 57 0.012
cellular glucose homeostasis GO:0001678 66 0.012
vascular process in circulatory system GO:0003018 96 0.012
glucan biosynthetic process GO:0009250 15 0.012
regulation of membrane potential GO:0042391 110 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
cell growth GO:0016049 104 0.012
amine metabolic process GO:0009308 38 0.012
regulation of neurotransmitter levels GO:0001505 42 0.012
vesicle fusion GO:0006906 14 0.012
cellular protein localization GO:0034613 122 0.012
regulation of nervous system development GO:0051960 264 0.012
metal ion homeostasis GO:0055065 186 0.012
synaptic transmission glutamatergic GO:0035249 33 0.012
regulation of peptide secretion GO:0002791 82 0.012
organic acid biosynthetic process GO:0016053 83 0.012
axon ensheathment GO:0008366 40 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
glycolytic process GO:0006096 17 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
regulation of insulin secretion GO:0050796 65 0.012
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.012
rhythmic process GO:0048511 156 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
single organism intracellular transport GO:1902582 166 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.011
blood circulation GO:0008015 183 0.011
response to insulin GO:0032868 133 0.011
monosaccharide biosynthetic process GO:0046364 16 0.011
regulation of tube size GO:0035150 89 0.011
protein tetramerization GO:0051262 38 0.011
positive regulation of transcription factor import into nucleus GO:0042993 4 0.011
lipid biosynthetic process GO:0008610 128 0.011
peptide hormone secretion GO:0030072 84 0.011
response to corticosteroid GO:0031960 235 0.011
axon development GO:0061564 96 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
response to reactive oxygen species GO:0000302 120 0.011
regulation of hormone levels GO:0010817 187 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
second messenger mediated signaling GO:0019932 51 0.011
negative regulation of cell death GO:0060548 229 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
organelle fusion GO:0048284 17 0.011
lipid storage GO:0019915 1 0.011
mitotic spindle organization GO:0007052 2 0.011
vesicle localization GO:0051648 33 0.011
cellular response to monosaccharide stimulus GO:0071326 67 0.011
positive regulation of adenylate cyclase activity GO:0045762 12 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
antigen processing and presentation GO:0019882 2 0.010
regulation of developmental growth GO:0048638 45 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
regulation of exocytosis GO:0017157 37 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
positive regulation of protein modification process GO:0031401 142 0.010
regulation of response to stress GO:0080134 126 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
cytoskeleton organization GO:0007010 111 0.010
circadian rhythm GO:0007623 88 0.010
positive regulation of cell differentiation GO:0045597 217 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010

Ak1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.066
carbohydrate metabolic disorder DOID:2978 0 0.066
inherited metabolic disorder DOID:655 0 0.066
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
central nervous system disease DOID:331 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.011
glucose metabolism disease DOID:4194 0 0.011
acquired metabolic disease DOID:0060158 0 0.011