Rattus norvegicus

0 known processes

Pank2

pantothenate kinase 2 (Hallervorden-Spatz syndrome)

Pank2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
behavior GO:0007610 205 0.152
cellular response to endogenous stimulus GO:0071495 377 0.112
intracellular signal transduction GO:0035556 314 0.095
regulation of catalytic activity GO:0050790 304 0.092
heart morphogenesis GO:0003007 3 0.088
negative regulation of cellular metabolic process GO:0031324 281 0.084
regulation of signal transduction GO:0009966 318 0.080
single organism behavior GO:0044708 130 0.075
response to nutrient GO:0007584 248 0.072
nucleic acid templated transcription GO:0097659 379 0.072
regulation of protein modification process GO:0031399 194 0.067
negative regulation of metabolic process GO:0009892 331 0.067
tissue development GO:0009888 252 0.065
cellular ketone metabolic process GO:0042180 51 0.064
reproductive process GO:0022414 372 0.060
cellular response to hormone stimulus GO:0032870 247 0.059
single organism catabolic process GO:0044712 283 0.059
carboxylic acid metabolic process GO:0019752 289 0.058
cell projection organization GO:0030030 302 0.058
cellular amino acid metabolic process GO:0006520 107 0.058
negative regulation of macromolecule metabolic process GO:0010605 260 0.057
positive regulation of biosynthetic process GO:0009891 319 0.056
response to molecule of bacterial origin GO:0002237 194 0.056
negative regulation of biosynthetic process GO:0009890 168 0.055
regulation of neurogenesis GO:0050767 247 0.055
response to radiation GO:0009314 137 0.055
rna biosynthetic process GO:0032774 380 0.053
catabolic process GO:0009056 351 0.052
positive regulation of cell differentiation GO:0045597 217 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.052
response to ethanol GO:0045471 162 0.051
reproduction GO:0000003 245 0.051
hormone metabolic process GO:0042445 69 0.050
rna metabolic process GO:0016070 406 0.049
oxoacid metabolic process GO:0043436 290 0.049
organic acid metabolic process GO:0006082 292 0.048
negative regulation of cellular biosynthetic process GO:0031327 161 0.048
transcription dna templated GO:0006351 377 0.047
multicellular organism reproduction GO:0032504 233 0.047
regulation of nervous system development GO:0051960 264 0.047
regulation of nucleic acid templated transcription GO:1903506 380 0.046
secretion by cell GO:0032940 248 0.046
regulation of transcription dna templated GO:0006355 374 0.045
response to bacterium GO:0009617 200 0.045
central nervous system development GO:0007417 311 0.044
positive regulation of cell communication GO:0010647 271 0.044
response to extracellular stimulus GO:0009991 380 0.044
regulation of cell development GO:0060284 263 0.044
development of primary sexual characteristics GO:0045137 107 0.043
chromosome segregation GO:0007059 2 0.042
response to hypoxia GO:0001666 231 0.042
steroid metabolic process GO:0008202 73 0.042
response to external biotic stimulus GO:0043207 221 0.042
neuron differentiation GO:0030182 368 0.042
regulation of molecular function GO:0065009 398 0.041
regulation of cell differentiation GO:0045595 320 0.041
multicellular organismal reproductive process GO:0048609 233 0.039
regulation of neuron death GO:1901214 115 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.039
pallium development GO:0021543 42 0.038
regulation of multicellular organismal development GO:2000026 376 0.038
neuron development GO:0048666 286 0.038
regulation of transferase activity GO:0051338 123 0.038
transcription from rna polymerase ii promoter GO:0006366 252 0.038
positive regulation of gene expression GO:0010628 244 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
positive regulation of transcription dna templated GO:0045893 197 0.037
purine nucleotide metabolic process GO:0006163 229 0.037
organic substance catabolic process GO:1901575 316 0.036
response to other organism GO:0051707 220 0.036
positive regulation of cellular biosynthetic process GO:0031328 295 0.036
response to nutrient levels GO:0031667 370 0.036
positive regulation of phosphate metabolic process GO:0045937 262 0.036
regulation of rna metabolic process GO:0051252 391 0.036
positive regulation of intracellular signal transduction GO:1902533 138 0.035
sex differentiation GO:0007548 113 0.034
response to oxygen levels GO:0070482 265 0.034
cellular component assembly GO:0022607 360 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
cellular response to stress GO:0033554 269 0.034
positive regulation of signaling GO:0023056 270 0.033
regulation of hormone levels GO:0010817 187 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
response to decreased oxygen levels GO:0036293 237 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.033
single organism reproductive process GO:0044702 297 0.033
positive regulation of neurogenesis GO:0050769 165 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
nucleotide metabolic process GO:0009117 279 0.031
cellular component biogenesis GO:0044085 368 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
cellular component morphogenesis GO:0032989 155 0.031
ribonucleotide biosynthetic process GO:0009260 85 0.031
circulatory system process GO:0003013 183 0.031
response to peptide hormone GO:0043434 278 0.031
programmed cell death GO:0012501 392 0.030
regulation of proteasomal protein catabolic process GO:0061136 4 0.030
organophosphate metabolic process GO:0019637 370 0.030
cellular catabolic process GO:0044248 295 0.030
vesicle mediated transport GO:0016192 181 0.030
muscle structure development GO:0061061 87 0.030
regulation of protein phosphorylation GO:0001932 183 0.030
negative regulation of cell communication GO:0010648 158 0.029
progesterone metabolic process GO:0042448 8 0.029
cellular component movement GO:0006928 248 0.029
positive regulation of signal transduction GO:0009967 175 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
gonad development GO:0008406 104 0.029
response to lipopolysaccharide GO:0032496 191 0.029
regulation of phosphorylation GO:0042325 248 0.029
regulation of protein metabolic process GO:0051246 289 0.029
macromolecular complex assembly GO:0065003 273 0.029
regulation of apoptotic process GO:0042981 335 0.028
protein complex biogenesis GO:0070271 263 0.028
organelle organization GO:0006996 266 0.028
response to biotic stimulus GO:0009607 226 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
organic cyclic compound catabolic process GO:1901361 175 0.028
heterocycle catabolic process GO:0046700 167 0.027
positive regulation of nervous system development GO:0051962 178 0.027
response to cytokine GO:0034097 215 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
cardiac chamber development GO:0003205 1 0.027
mesenchymal to epithelial transition GO:0060231 3 0.026
aging GO:0007568 241 0.026
meiotic cell cycle process GO:1903046 3 0.026
neuron projection development GO:0031175 273 0.026
response to peptide GO:1901652 292 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
protein complex assembly GO:0006461 263 0.025
immune system process GO:0002376 204 0.025
organophosphate biosynthetic process GO:0090407 143 0.025
regulation of cytokine biosynthetic process GO:0042035 3 0.025
positive regulation of protein metabolic process GO:0051247 178 0.025
cellular hormone metabolic process GO:0034754 49 0.025
reactive oxygen species biosynthetic process GO:1903409 8 0.025
cardiac ventricle development GO:0003231 1 0.025
synaptic transmission GO:0007268 235 0.025
negative regulation of transcription dna templated GO:0045892 116 0.024
positive regulation of protein modification process GO:0031401 142 0.024
response to inorganic substance GO:0010035 377 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
blood circulation GO:0008015 183 0.024
negative regulation of nucleic acid templated transcription GO:1903507 117 0.024
response to alkaloid GO:0043279 132 0.024
regulation of locomotion GO:0040012 148 0.024
negative regulation of gene expression GO:0010629 199 0.024
amine metabolic process GO:0009308 38 0.024
response to ionizing radiation GO:0010212 59 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
negative regulation of rna metabolic process GO:0051253 123 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
oxidation reduction process GO:0055114 304 0.023
circadian rhythm GO:0007623 88 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
epithelial cell differentiation GO:0030855 71 0.022
regulation of cellular component organization GO:0051128 368 0.022
peptidyl amino acid modification GO:0018193 126 0.022
protein phosphorylation GO:0006468 345 0.022
cell migration GO:0016477 197 0.022
positive regulation of cell development GO:0010720 176 0.022
sexual reproduction GO:0019953 148 0.022
motor neuron axon guidance GO:0008045 1 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
positive regulation of molecular function GO:0044093 230 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
response to vitamin GO:0033273 131 0.021
cytokine biosynthetic process GO:0042089 3 0.021
muscle tissue development GO:0060537 58 0.021
apoptotic process GO:0006915 381 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
head development GO:0060322 247 0.020
regulation of protein kinase activity GO:0045859 105 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
cell part morphogenesis GO:0032990 123 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
regulation of cell projection organization GO:0031344 175 0.020
cell differentiation involved in kidney development GO:0061005 4 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
anterior posterior pattern specification GO:0009952 1 0.019
negative regulation of signaling GO:0023057 157 0.019
developmental growth GO:0048589 100 0.019
ras protein signal transduction GO:0007265 29 0.019
gliogenesis GO:0042063 93 0.019
regulation of catabolic process GO:0009894 113 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
neuron death GO:0070997 127 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
cellular amine metabolic process GO:0044106 38 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
regulation of kinase activity GO:0043549 117 0.018
response to ketone GO:1901654 182 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.018
epithelium development GO:0060429 96 0.018
cellular response to peptide GO:1901653 133 0.018
multi organism reproductive process GO:0044703 262 0.018
ribose phosphate biosynthetic process GO:0046390 87 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
intracellular transport GO:0046907 185 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
regulation of neuron differentiation GO:0045664 208 0.018
hepaticobiliary system development GO:0061008 90 0.018
protein complex subunit organization GO:0071822 302 0.018
developmental process involved in reproduction GO:0003006 159 0.018
purine containing compound biosynthetic process GO:0072522 85 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
nucleoside metabolic process GO:0009116 179 0.018
cellular response to cytokine stimulus GO:0071345 127 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.018
regulation of neuron projection development GO:0010975 161 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
response to insulin GO:0032868 133 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
heart development GO:0007507 72 0.017
embryonic pattern specification GO:0009880 1 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
single organism organelle organization GO:1902589 180 0.017
cytoskeleton organization GO:0007010 111 0.017
positive regulation of transferase activity GO:0051347 81 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
brain development GO:0007420 247 0.017
negative regulation of phosphorus metabolic process GO:0010563 80 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
positive regulation of developmental process GO:0051094 283 0.016
telencephalon development GO:0021537 62 0.016
liver development GO:0001889 90 0.016
aromatic compound catabolic process GO:0019439 168 0.016
male mating behavior GO:0060179 3 0.016
negative regulation of cell death GO:0060548 229 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
epithelial cell differentiation involved in kidney development GO:0035850 3 0.016
multicellular organism growth GO:0035264 1 0.016
dicarboxylic acid metabolic process GO:0043648 42 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
purine containing compound metabolic process GO:0072521 253 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
lipid metabolic process GO:0006629 283 0.016
cellular lipid metabolic process GO:0044255 208 0.016
purine ribonucleotide biosynthetic process GO:0009152 81 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
eye morphogenesis GO:0048592 4 0.015
regulation of cellular localization GO:0060341 263 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
regulation of lipid metabolic process GO:0019216 68 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
muscle contraction GO:0006936 88 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
cellular response to lipid GO:0071396 201 0.015
cell projection morphogenesis GO:0048858 123 0.015
multi multicellular organism process GO:0044706 138 0.015
nephron tubule epithelial cell differentiation GO:0072160 1 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
response to growth factor GO:0070848 189 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
cell morphogenesis GO:0000902 142 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
chemosensory behavior GO:0007635 2 0.015
phthalate metabolic process GO:0018963 8 0.015
neurological system process GO:0050877 219 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
embryonic axis specification GO:0000578 1 0.015
isoprenoid metabolic process GO:0006720 45 0.015
regulation of mapk cascade GO:0043408 116 0.015
mesenchymal cell proliferation GO:0010463 4 0.015
response to metal ion GO:0010038 253 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.014
tube development GO:0035295 89 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
eye development GO:0001654 50 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
negative regulation of signal transduction GO:0009968 83 0.014
response to estrogen GO:0043627 232 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
regulation of nucleotide biosynthetic process GO:0030808 47 0.014
muscle cell proliferation GO:0033002 84 0.014
steroid biosynthetic process GO:0006694 48 0.014
growth GO:0040007 165 0.014
defense response GO:0006952 194 0.014
positive regulation of transcription factor import into nucleus GO:0042993 4 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
mapk cascade GO:0000165 140 0.014
regulation of system process GO:0044057 208 0.014
response to glucose GO:0009749 136 0.014
digestive tract development GO:0048565 39 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
forebrain development GO:0030900 98 0.014
purine nucleoside metabolic process GO:0042278 169 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
regulation of growth GO:0040008 105 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
gamete generation GO:0007276 124 0.013
axis specification GO:0009798 4 0.013
single organism intracellular transport GO:1902582 166 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
c21 steroid hormone metabolic process GO:0008207 14 0.013
negative regulation of cell development GO:0010721 82 0.013
cell motility GO:0048870 202 0.013
response to acid chemical GO:0001101 222 0.013
chromosome separation GO:0051304 1 0.013
positive regulation of necroptotic process GO:0060545 2 0.013
response to oxidative stress GO:0006979 186 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
regulation of jak stat cascade GO:0046425 21 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
response to wounding GO:0009611 254 0.013
cytoplasmic transport GO:0016482 115 0.013
organ morphogenesis GO:0009887 75 0.013
proteolysis GO:0006508 175 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
gastrulation GO:0007369 2 0.012
olfactory behavior GO:0042048 2 0.012
purine containing compound catabolic process GO:0072523 138 0.012
microtubule organizing center organization GO:0031023 1 0.012
positive regulation of cell death GO:0010942 184 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
locomotion GO:0040011 237 0.012
single organism biosynthetic process GO:0044711 342 0.012
homeostatic process GO:0042592 331 0.012
peptidyl tyrosine modification GO:0018212 72 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
regulation of notch signaling pathway GO:0008593 3 0.012
transmission of nerve impulse GO:0019226 42 0.012
dephosphorylation GO:0016311 98 0.012
regulation of small gtpase mediated signal transduction GO:0051056 48 0.012
asymmetric protein localization GO:0008105 2 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
reproductive structure development GO:0048608 128 0.012
jak stat cascade GO:0007259 26 0.012
single organism cellular localization GO:1902580 102 0.011
male sex differentiation GO:0046661 64 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
amide transport GO:0042886 105 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
regulation of programmed cell death GO:0043067 341 0.011
limbic system development GO:0021761 38 0.011
regulation of cell proliferation GO:0042127 359 0.011
sister chromatid segregation GO:0000819 1 0.011
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.011
male gamete generation GO:0048232 99 0.011
erk1 and erk2 cascade GO:0070371 48 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
circulatory system development GO:0072359 134 0.011
cell cycle GO:0007049 101 0.011
localization of cell GO:0051674 202 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
reproductive system development GO:0061458 128 0.011
response to corticosteroid GO:0031960 235 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
regulation of nephron tubule epithelial cell differentiation GO:0072182 1 0.010
response to electrical stimulus involved in regulation of muscle adaptation GO:0014878 4 0.010
nucleotide catabolic process GO:0009166 139 0.010
axonogenesis GO:0007409 71 0.010
regulation of chromosome segregation GO:0051983 1 0.010
regulation of response to stress GO:0080134 126 0.010
cellular macromolecule localization GO:0070727 122 0.010
negative regulation of neuron death GO:1901215 69 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
biological adhesion GO:0022610 110 0.010
cell adhesion GO:0007155 110 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
cellular response to alcohol GO:0097306 87 0.010
regulation of metanephros development GO:0072215 4 0.010
response to glucocorticoid GO:0051384 223 0.010
response to monosaccharide GO:0034284 159 0.010
lipid biosynthetic process GO:0008610 128 0.010
negative regulation of cell differentiation GO:0045596 99 0.010

Pank2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
disease of anatomical entity DOID:7 0 0.010
Human
musculoskeletal system disease DOID:17 0 0.010