Rattus norvegicus

5 known processes

Serping1

serine (or cysteine) peptidase inhibitor, clade G, member 1

(Aliases: MGC72585)

Serping1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
complement activation GO:0006956 11 0.995
Human
immune effector process GO:0002252 53 0.861
Human
innate immune response GO:0045087 35 0.482
Human
response to nutrient levels GO:0031667 370 0.439
response to external biotic stimulus GO:0043207 221 0.342
protein activation cascade GO:0072376 12 0.334
Human
response to extracellular stimulus GO:0009991 380 0.298
response to other organism GO:0051707 220 0.278
jak stat cascade GO:0007259 26 0.264
response to molecule of bacterial origin GO:0002237 194 0.253
response to biotic stimulus GO:0009607 226 0.233
leukocyte mediated immunity GO:0002443 28 0.194
response to lipopolysaccharide GO:0032496 191 0.187
positive regulation of response to stimulus GO:0048584 285 0.173
Human Rat
cellular response to cytokine stimulus GO:0071345 127 0.159
response to metal ion GO:0010038 253 0.159
Rat
response to nutrient GO:0007584 248 0.158
response to interleukin 1 GO:0070555 55 0.156
coagulation GO:0050817 28 0.132
Rat
immune response GO:0006955 104 0.126
Human
activation of immune response GO:0002253 26 0.113
Human
cellular response to interleukin 1 GO:0071347 37 0.108
regulation of cell projection organization GO:0031344 175 0.105
Rat
response to glucose GO:0009749 136 0.104
Rat
response to camp GO:0051591 91 0.103
immune system process GO:0002376 204 0.101
Human
response to cytokine GO:0034097 215 0.097
negative regulation of multicellular organismal process GO:0051241 203 0.097
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.094
protein maturation GO:0051604 68 0.092
Human Mouse
cellular response to lipid GO:0071396 201 0.090
Rat
aging GO:0007568 241 0.087
antigen processing and presentation GO:0019882 2 0.084
response to interferon alpha GO:0035455 1 0.081
positive regulation of immune system process GO:0002684 90 0.080
Human
rna biosynthetic process GO:0032774 380 0.074
response to interferon beta GO:0035456 1 0.073
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.068
regulation of viral transcription GO:0046782 2 0.061
negative regulation of gene expression GO:0010629 199 0.059
Human Mouse Rat
multi organism reproductive process GO:0044703 262 0.056
cellular response to molecule of bacterial origin GO:0071219 56 0.055
peptide cross linking GO:0018149 1 0.055
response to hexose GO:0009746 144 0.050
Rat
response to bacterium GO:0009617 200 0.050
viral transcription GO:0019083 2 0.049
reactive oxygen species metabolic process GO:0072593 37 0.049
embryonic skeletal system development GO:0048706 3 0.046
regulation of nucleotide biosynthetic process GO:0030808 47 0.046
cellular catabolic process GO:0044248 295 0.046
carbohydrate derivative biosynthetic process GO:1901137 124 0.044
regulation of neurogenesis GO:0050767 247 0.044
Rat
lymphocyte mediated immunity GO:0002449 14 0.043
reproductive process GO:0022414 372 0.042
Rat
regulation of nervous system development GO:0051960 264 0.042
Rat
positive regulation of nervous system development GO:0051962 178 0.042
Rat
negative regulation of metabolic process GO:0009892 331 0.042
Human Mouse Rat
glial cell differentiation GO:0010001 65 0.042
cellular response to oxygen containing compound GO:1901701 386 0.041
Rat
viral gene expression GO:0019080 2 0.041
regulation of cell activation GO:0050865 50 0.040
very low density lipoprotein particle remodeling GO:0034372 1 0.040
positive regulation of neuron projection development GO:0010976 99 0.040
Rat
inflammatory response GO:0006954 150 0.040
Human Rat
negative regulation of developmental process GO:0051093 125 0.040
respiratory system development GO:0060541 45 0.038
regulation of tolerance induction to nonself antigen GO:0002655 1 0.037
regulation of viral entry into host cell GO:0046596 3 0.037
response to inorganic substance GO:0010035 377 0.037
Rat
rhythmic process GO:0048511 156 0.037
Rat
positive regulation of gene expression GO:0010628 244 0.036
cell part morphogenesis GO:0032990 123 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
morphogenesis of a polarized epithelium GO:0001738 1 0.036
negative regulation of cellular metabolic process GO:0031324 281 0.035
Human Mouse Rat
negative regulation of apoptotic process GO:0043066 181 0.035
organic substance catabolic process GO:1901575 316 0.035
viral genome replication GO:0019079 2 0.035
peptidyl amino acid modification GO:0018193 126 0.035
organonitrogen compound biosynthetic process GO:1901566 167 0.034
negative regulation of innate immune response GO:0045824 4 0.034
Human
positive regulation of neurogenesis GO:0050769 165 0.033
Rat
defense response GO:0006952 194 0.033
Human Rat
carbohydrate derivative metabolic process GO:1901135 346 0.033
negative regulation of viral entry into host cell GO:0046597 3 0.033
purine containing compound biosynthetic process GO:0072522 85 0.032
protein homotrimerization GO:0070207 15 0.032
negative regulation of proteolysis GO:0045861 41 0.032
Human Mouse Rat
skeletal system development GO:0001501 41 0.032
regulation of innate immune response GO:0045088 15 0.032
Human
chemical homeostasis GO:0048878 292 0.032
Rat
cellular amine metabolic process GO:0044106 38 0.031
regulation of purine nucleotide metabolic process GO:1900542 115 0.030
head development GO:0060322 247 0.030
programmed cell death GO:0012501 392 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
Rat
carbohydrate homeostasis GO:0033500 75 0.029
Rat
regulation of rna metabolic process GO:0051252 391 0.029
liver development GO:0001889 90 0.029
cellular response to interleukin 2 GO:0071352 1 0.029
glycosyl compound metabolic process GO:1901657 182 0.029
regulation of blood circulation GO:1903522 110 0.029
receptor mediated endocytosis GO:0006898 42 0.028
catabolic process GO:0009056 351 0.028
multi multicellular organism process GO:0044706 138 0.028
reproductive system development GO:0061458 128 0.028
anterior posterior pattern specification GO:0009952 1 0.028
rna metabolic process GO:0016070 406 0.028
lung development GO:0030324 43 0.027
b cell mediated immunity GO:0019724 4 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
Human Mouse Rat
intracellular signal transduction GO:0035556 314 0.027
immunoglobulin mediated immune response GO:0016064 4 0.027
tissue remodeling GO:0048771 40 0.027
response to glucocorticoid GO:0051384 223 0.026
Rat
regulation of cell differentiation GO:0045595 320 0.026
Rat
amine metabolic process GO:0009308 38 0.026
regulation of protein maturation GO:1903317 50 0.026
Human Mouse Rat
negative regulation of viral process GO:0048525 4 0.026
positive regulation of cell projection organization GO:0031346 111 0.026
Rat
cell projection morphogenesis GO:0048858 123 0.025
purine nucleotide biosynthetic process GO:0006164 83 0.025
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
response to ethanol GO:0045471 162 0.025
homeostatic process GO:0042592 331 0.025
Rat
response to hypoxia GO:0001666 231 0.025
regulation of protein metabolic process GO:0051246 289 0.025
Human Mouse Rat
response to purine containing compound GO:0014074 126 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
cell projection organization GO:0030030 302 0.024
Rat
kidney development GO:0001822 67 0.024
Rat
axon development GO:0061564 96 0.024
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
Human Mouse Rat
regulation of cellular component organization GO:0051128 368 0.022
Rat
t cell tolerance induction GO:0002517 3 0.022
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.022
organic acid metabolic process GO:0006082 292 0.022
camp metabolic process GO:0046058 63 0.022
tissue development GO:0009888 252 0.022
Rat
cyclic nucleotide metabolic process GO:0009187 80 0.022
response to interferon gamma GO:0034341 20 0.021
oxoacid metabolic process GO:0043436 290 0.021
regulation of peptidase activity GO:0052547 55 0.021
Human Mouse Rat
cyclic nucleotide biosynthetic process GO:0009190 63 0.021
neuron projection morphogenesis GO:0048812 122 0.021
regulation of camp biosynthetic process GO:0030817 38 0.021
chylomicron remodeling GO:0034371 1 0.020
multicellular organism reproduction GO:0032504 233 0.020
Rat
transmembrane transport GO:0055085 412 0.020
tolerance induction dependent upon immune response GO:0002461 2 0.020
negative regulation of protein metabolic process GO:0051248 114 0.019
Human Mouse Rat
regulation of proteolysis GO:0030162 66 0.019
Human Mouse Rat
cellular response to extracellular stimulus GO:0031668 73 0.019
adaptive immune response GO:0002250 14 0.019
macromolecular complex assembly GO:0065003 273 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
Rat
antigen processing and presentation of peptide antigen GO:0048002 2 0.019
cellular component assembly GO:0022607 360 0.018
mitotic spindle organization GO:0007052 2 0.018
regulation of signal transduction GO:0009966 318 0.018
negative regulation of cytokine production GO:0001818 16 0.018
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.018
regulation of developmental growth GO:0048638 45 0.018
signal transduction by phosphorylation GO:0023014 144 0.018
response to organophosphorus GO:0046683 102 0.018
cellular response to metal ion GO:0071248 55 0.017
Rat
negative regulation of neuron death GO:1901215 69 0.017
Rat
negative regulation of peptidase activity GO:0010466 38 0.017
Human Mouse Rat
proteolysis GO:0006508 175 0.017
Human Mouse Rat
striated muscle tissue development GO:0014706 58 0.017
cellular response to external stimulus GO:0071496 118 0.017
cellular response to hexose stimulus GO:0071331 65 0.017
Rat
response to interleukin 2 GO:0070669 1 0.016
axonogenesis GO:0007409 71 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
cellular response to alcohol GO:0097306 87 0.016
Rat
positive regulation of cyclase activity GO:0031281 15 0.016
lipid localization GO:0010876 62 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
ion homeostasis GO:0050801 212 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
negative regulation of molecular function GO:0044092 133 0.016
Human Mouse Rat
camp biosynthetic process GO:0006171 47 0.016
regulation of immune response GO:0050776 55 0.016
Human
response to wounding GO:0009611 254 0.016
Human Rat
purine nucleotide metabolic process GO:0006163 229 0.015
response to monosaccharide GO:0034284 159 0.015
Rat
response to decreased oxygen levels GO:0036293 237 0.015
positive regulation of immune response GO:0050778 42 0.015
Human
vasculogenesis GO:0001570 3 0.015
ras protein signal transduction GO:0007265 29 0.015
regulation of hydrolase activity GO:0051336 143 0.015
Human Mouse Rat
blood coagulation fibrin clot formation GO:0072378 1 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
regulation of extent of cell growth GO:0061387 25 0.015
positive regulation of cellular component organization GO:0051130 200 0.014
Rat
respiratory tube development GO:0030323 43 0.014
central nervous system development GO:0007417 311 0.014
growth GO:0040007 165 0.014
regulation of cell proliferation GO:0042127 359 0.014
negative regulation of endopeptidase activity GO:0010951 36 0.014
Human Mouse Rat
cellular response to endogenous stimulus GO:0071495 377 0.014
Rat
cellular response to stress GO:0033554 269 0.014
circulatory system development GO:0072359 134 0.014
ovulation cycle GO:0042698 67 0.014
Rat
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
regulation of catalytic activity GO:0050790 304 0.013
Human Mouse Rat
regulation of cell development GO:0060284 263 0.013
Rat
regulation of immune system process GO:0002682 123 0.013
Human
single organism reproductive process GO:0044702 297 0.013
Rat
positive regulation of developmental process GO:0051094 283 0.013
Rat
glucose homeostasis GO:0042593 75 0.013
Rat
endocytosis GO:0006897 84 0.013
regulation of activation of janus kinase activity GO:0010533 1 0.013
cellular response to biotic stimulus GO:0071216 59 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
Rat
negative regulation of catalytic activity GO:0043086 103 0.013
Human Mouse Rat
regulation of axonogenesis GO:0050770 37 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
response to estradiol GO:0032355 164 0.013
negative regulation of cell death GO:0060548 229 0.013
Rat
cellular chemical homeostasis GO:0055082 247 0.012
Rat
cellular response to nutrient levels GO:0031669 60 0.012
response to estrogen GO:0043627 232 0.012
purine nucleobase metabolic process GO:0006144 4 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
morphogenesis of an epithelium GO:0002009 20 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
heart development GO:0007507 72 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
protein complex biogenesis GO:0070271 263 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
developmental process involved in reproduction GO:0003006 159 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
response to retinoic acid GO:0032526 63 0.011
Rat
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
reproduction GO:0000003 245 0.011
Rat
single organism catabolic process GO:0044712 283 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
negative regulation of protein maturation GO:1903318 47 0.011
Human Mouse Rat
regulation of locomotion GO:0040012 148 0.011
Rat
positive regulation of cell differentiation GO:0045597 217 0.011
Rat
regulation of viral genome replication GO:0045069 2 0.011
positive regulation of molecular function GO:0044093 230 0.011
response to virus GO:0009615 17 0.011
regulation of tolerance induction GO:0002643 2 0.011
cardiovascular system development GO:0072358 134 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
brain development GO:0007420 247 0.011
cellular response to inorganic substance GO:0071241 65 0.011
Rat
regulation of endopeptidase activity GO:0052548 51 0.011
Human Mouse Rat
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
hepaticobiliary system development GO:0061008 90 0.010
regulation of catabolic process GO:0009894 113 0.010
regulation of neuron differentiation GO:0045664 208 0.010
Rat
negative regulation of viral genome replication GO:0045071 1 0.010
response to food GO:0032094 27 0.010
positive regulation of phosphorus metabolic process GO:0010562 262 0.010
regulation of rna biosynthetic process GO:2001141 381 0.010
response to corticosteroid GO:0031960 235 0.010
Rat
protein phosphorylation GO:0006468 345 0.010
male mating behavior GO:0060179 3 0.010
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.010
protein lipid complex remodeling GO:0034368 1 0.010

Serping1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
acquired metabolic disease DOID:0060158 0 0.025
disease of anatomical entity DOID:7 0 0.020
Human
vascular disease DOID:178 0 0.020
cardiovascular system disease DOID:1287 0 0.020
nervous system disease DOID:863 0 0.015
retinal disease DOID:5679 0 0.014
retinal degeneration DOID:8466 0 0.014
degeneration of macula and posterior pole DOID:2007 0 0.014
sensory system disease DOID:0050155 0 0.014
macular degeneration DOID:4448 0 0.014
eye and adnexa disease DOID:1492 0 0.014
age related macular degeneration DOID:10871 0 0.014
eye disease DOID:5614 0 0.014
artery disease DOID:0050828 0 0.013