Rattus norvegicus

36 known processes

Vkorc1

vitamin K epoxide reductase complex, subunit 1

Vkorc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.384
peptidyl glutamic acid modification GO:0018200 1 0.160
Human
jak stat cascade GO:0007259 26 0.077
positive regulation of signaling GO:0023056 270 0.074
positive regulation of jak stat cascade GO:0046427 19 0.071
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 1 0.068
neuron apoptotic process GO:0051402 88 0.054
reproductive process GO:0022414 372 0.045
camera type eye development GO:0043010 48 0.045
response to ketone GO:1901654 182 0.044
positive regulation of intracellular signal transduction GO:1902533 138 0.042
response to vitamin k GO:0032571 4 0.041
cellular response to oxidative stress GO:0034599 76 0.041
regulation of protein metabolic process GO:0051246 289 0.039
positive regulation of cell communication GO:0010647 271 0.034
positive regulation of catalytic activity GO:0043085 184 0.032
regulation of molecular function GO:0065009 398 0.031
neuron death GO:0070997 127 0.031
secretion by cell GO:0032940 248 0.031
positive regulation of response to stimulus GO:0048584 285 0.030
negative regulation of neuron death GO:1901215 69 0.029
chemical homeostasis GO:0048878 292 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.028
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
response to acid chemical GO:0001101 222 0.026
secretion GO:0046903 307 0.026
regulation of neurogenesis GO:0050767 247 0.026
regulation of neuron differentiation GO:0045664 208 0.026
regulation of jak stat cascade GO:0046425 21 0.026
neuron differentiation GO:0030182 368 0.025
positive regulation of protein metabolic process GO:0051247 178 0.024
regulation of catalytic activity GO:0050790 304 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
regulation of hormone levels GO:0010817 187 0.023
defense response GO:0006952 194 0.022
response to cold GO:0009409 29 0.022
cellular response to stress GO:0033554 269 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
negative regulation of immune system process GO:0002683 39 0.021
protein complex assembly GO:0006461 263 0.020
hormone metabolic process GO:0042445 69 0.020
organic acid metabolic process GO:0006082 292 0.020
single organism reproductive process GO:0044702 297 0.019
pyrimidine nucleotide metabolic process GO:0006220 9 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
cellular homeostasis GO:0019725 252 0.019
multicellular organism reproduction GO:0032504 233 0.018
cellular component assembly GO:0022607 360 0.018
positive regulation of molecular function GO:0044093 230 0.018
reactive oxygen species metabolic process GO:0072593 37 0.018
regulation of neuron death GO:1901214 115 0.018
response to hexose GO:0009746 144 0.017
cell cell signaling GO:0007267 335 0.017
intracellular signal transduction GO:0035556 314 0.017
response to inorganic substance GO:0010035 377 0.017
regulation of behavior GO:0050795 61 0.017
pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 3 0.016
cellular response to hexose stimulus GO:0071331 65 0.016
immune system process GO:0002376 204 0.016
oxoacid metabolic process GO:0043436 290 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
signal release GO:0023061 145 0.016
gamete generation GO:0007276 124 0.016
regulation of nervous system development GO:0051960 264 0.016
regulation of neuron projection development GO:0010975 161 0.016
homeostatic process GO:0042592 331 0.015
response to oxidative stress GO:0006979 186 0.015
cellular chemical homeostasis GO:0055082 247 0.015
hormone secretion GO:0046879 115 0.014
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.014
cellular hormone metabolic process GO:0034754 49 0.014
regulation of cell aging GO:0090342 1 0.014
response to peptide hormone GO:0043434 278 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
response to ethanol GO:0045471 162 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
hydrogen peroxide metabolic process GO:0042743 13 0.013
regulation of proteolysis GO:0030162 66 0.013
carbohydrate homeostasis GO:0033500 75 0.013
proteolysis GO:0006508 175 0.013
sexual reproduction GO:0019953 148 0.013
multi organism reproductive process GO:0044703 262 0.013
positive regulation of apoptotic process GO:0043065 154 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
leukocyte differentiation GO:0002521 30 0.012
spermatogenesis GO:0007283 99 0.012
regulation of apoptotic process GO:0042981 335 0.012
regulation of peptidase activity GO:0052547 55 0.012
cellular response to carbohydrate stimulus GO:0071322 72 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
sodium ion transport GO:0006814 82 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
inflammatory response GO:0006954 150 0.012
metal ion transport GO:0030001 289 0.012
regulation of signal transduction GO:0009966 318 0.012
reproduction GO:0000003 245 0.012
glucose homeostasis GO:0042593 75 0.012
response to peptide GO:1901652 292 0.012
intestinal absorption GO:0050892 3 0.012
regulation of cellular component organization GO:0051128 368 0.011
negative regulation of defense response GO:0031348 19 0.011
male gamete generation GO:0048232 99 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.011
single organism behavior GO:0044708 130 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regulation of cell projection organization GO:0031344 175 0.011
regulation of cell development GO:0060284 263 0.011
positive regulation of developmental process GO:0051094 283 0.011
cellular glucose homeostasis GO:0001678 66 0.011
negative regulation of metabolic process GO:0009892 331 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.011
cellular cation homeostasis GO:0030003 180 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
response to purine containing compound GO:0014074 126 0.011
pyrimidine ribonucleoside triphosphate biosynthetic process GO:0009209 2 0.011
response to glucose GO:0009749 136 0.010
positive regulation of signal transduction GO:0009967 175 0.010
negative regulation of cell death GO:0060548 229 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010
negative regulation of protein modification by small protein conjugation or removal GO:1903321 4 0.010
ctp biosynthetic process GO:0006241 1 0.010
sulfur compound metabolic process GO:0006790 70 0.010

Vkorc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.053
bone disease DOID:0080001 0 0.053
disease of anatomical entity DOID:7 0 0.053
musculoskeletal system disease DOID:17 0 0.053
connective tissue disease DOID:65 0 0.053
disease of metabolism DOID:0014667 0 0.031
inherited metabolic disorder DOID:655 0 0.017