Rattus norvegicus

0 known processes

Epx

eosinophil peroxidase

Epx biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
anatomical structure morphogenesis GO:0009653 298 0.164
regulation of cell proliferation GO:0042127 359 0.152
negative regulation of cell proliferation GO:0008285 119 0.138
positive regulation of multicellular organismal process GO:0051240 387 0.113
regulation of anatomical structure morphogenesis GO:0022603 141 0.104
neuron differentiation GO:0030182 368 0.085
cell motility GO:0048870 202 0.081
regulation of multicellular organismal development GO:2000026 376 0.080
negative regulation of multicellular organismal process GO:0051241 203 0.080
tissue development GO:0009888 252 0.071
response to oxygen levels GO:0070482 265 0.069
cell projection organization GO:0030030 302 0.067
regulation of cell development GO:0060284 263 0.066
urogenital system development GO:0001655 78 0.064
cellular response to lipid GO:0071396 201 0.064
locomotion GO:0040011 237 0.064
nucleobase containing small molecule metabolic process GO:0055086 316 0.063
regulation of apoptotic process GO:0042981 335 0.062
regulation of cell differentiation GO:0045595 320 0.059
head development GO:0060322 247 0.056
epithelium development GO:0060429 96 0.055
regulation of cell projection organization GO:0031344 175 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
cell migration GO:0016477 197 0.051
apoptotic process GO:0006915 381 0.050
regulation of phosphate metabolic process GO:0019220 349 0.050
cellular response to oxygen containing compound GO:1901701 386 0.048
positive regulation of cell proliferation GO:0008284 249 0.047
response to retinoic acid GO:0032526 63 0.046
cellular component movement GO:0006928 248 0.045
response to bacterium GO:0009617 200 0.045
Rat
tube development GO:0035295 89 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
regulation of cellular component organization GO:0051128 368 0.043
negative regulation of developmental process GO:0051093 125 0.043
single organism reproductive process GO:0044702 297 0.042
rna metabolic process GO:0016070 406 0.042
rna biosynthetic process GO:0032774 380 0.042
localization of cell GO:0051674 202 0.041
negative regulation of gene expression GO:0010629 199 0.041
positive regulation of programmed cell death GO:0043068 157 0.040
regulation of neuron differentiation GO:0045664 208 0.040
reproduction GO:0000003 245 0.038
positive regulation of cell death GO:0010942 184 0.038
regulation of neurogenesis GO:0050767 247 0.038
intracellular signal transduction GO:0035556 314 0.038
negative regulation of cell differentiation GO:0045596 99 0.037
regulation of nucleic acid templated transcription GO:1903506 380 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.036
positive regulation of cellular component organization GO:0051130 200 0.036
single organism biosynthetic process GO:0044711 342 0.036
response to wounding GO:0009611 254 0.035
cellular component biogenesis GO:0044085 368 0.035
nucleotide metabolic process GO:0009117 279 0.035
positive regulation of developmental process GO:0051094 283 0.035
reproductive process GO:0022414 372 0.034
formation of primary germ layer GO:0001704 1 0.033
protein localization GO:0008104 191 0.033
neuron projection development GO:0031175 273 0.033
cellular component assembly GO:0022607 360 0.032
regulation of molecular function GO:0065009 398 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
central nervous system development GO:0007417 311 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.031
positive regulation of gene expression GO:0010628 244 0.030
organ regeneration GO:0031100 101 0.030
regulation of rna metabolic process GO:0051252 391 0.030
female pregnancy GO:0007565 122 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.029
regulation of cell motility GO:2000145 131 0.029
response to extracellular stimulus GO:0009991 380 0.029
Rat
regulation of neuron projection development GO:0010975 161 0.029
cellular ketone metabolic process GO:0042180 51 0.029
cation transport GO:0006812 382 0.028
cellular protein localization GO:0034613 122 0.028
homeostatic process GO:0042592 331 0.028
cellular response to organonitrogen compound GO:0071417 197 0.028
regulation of transcription dna templated GO:0006355 374 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
negative regulation of metabolic process GO:0009892 331 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
regulation of vasculature development GO:1901342 44 0.027
proteolysis GO:0006508 175 0.027
response to peptide GO:1901652 292 0.027
transcription dna templated GO:0006351 377 0.027
response to nutrient GO:0007584 248 0.027
negative regulation of synaptic transmission dopaminergic GO:0032227 4 0.027
positive regulation of apoptotic process GO:0043065 154 0.027
multicellular organismal signaling GO:0035637 44 0.027
gastrulation GO:0007369 2 0.027
myelination GO:0042552 39 0.026
response to hypoxia GO:0001666 231 0.026
response to lipopolysaccharide GO:0032496 191 0.026
Rat
blood vessel morphogenesis GO:0048514 58 0.026
cellular component morphogenesis GO:0032989 155 0.026
protein complex assembly GO:0006461 263 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
multi organism reproductive process GO:0044703 262 0.025
smooth muscle cell proliferation GO:0048659 77 0.025
ribonucleoside metabolic process GO:0009119 174 0.025
anatomical structure formation involved in morphogenesis GO:0048646 83 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
response to nutrient levels GO:0031667 370 0.025
Rat
regulation of nervous system development GO:0051960 264 0.025
regulation of programmed cell death GO:0043067 341 0.024
aromatic compound catabolic process GO:0019439 168 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
gamete generation GO:0007276 124 0.024
negative regulation of signaling GO:0023057 157 0.024
response to metal ion GO:0010038 253 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
response to acid chemical GO:0001101 222 0.024
gland development GO:0048732 155 0.024
cell morphogenesis involved in differentiation GO:0000904 119 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
macromolecule localization GO:0033036 252 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
angiogenesis GO:0001525 53 0.023
oxoacid metabolic process GO:0043436 290 0.023
purine containing compound metabolic process GO:0072521 253 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
single organism cellular localization GO:1902580 102 0.022
macromolecular complex assembly GO:0065003 273 0.022
multicellular organism reproduction GO:0032504 233 0.022
regulation of catalytic activity GO:0050790 304 0.022
response to organophosphorus GO:0046683 102 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
positive regulation of cell migration GO:0030335 96 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
cardiovascular system development GO:0072358 134 0.022
nucleic acid templated transcription GO:0097659 379 0.021
regulation of anatomical structure size GO:0090066 135 0.021
behavior GO:0007610 205 0.021
neuron development GO:0048666 286 0.021
response to peptide hormone GO:0043434 278 0.021
hepaticobiliary system development GO:0061008 90 0.021
response to biotic stimulus GO:0009607 226 0.021
Rat
regulation of cell migration GO:0030334 128 0.021
regulation of hydrolase activity GO:0051336 143 0.021
response to radiation GO:0009314 137 0.021
chemical homeostasis GO:0048878 292 0.020
brain development GO:0007420 247 0.020
negative regulation of rna metabolic process GO:0051253 123 0.020
cellular response to retinoic acid GO:0071300 27 0.020
regulation of signal transduction GO:0009966 318 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
protein complex biogenesis GO:0070271 263 0.020
vasculature development GO:0001944 70 0.020
organic acid biosynthetic process GO:0016053 83 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
positive regulation of nervous system development GO:0051962 178 0.020
regulation of protein metabolic process GO:0051246 289 0.019
response to estrogen GO:0043627 232 0.019
response to hexose GO:0009746 144 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
forebrain development GO:0030900 98 0.019
liver development GO:0001889 90 0.019
rhythmic process GO:0048511 156 0.019
response to decreased oxygen levels GO:0036293 237 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
cell type specific apoptotic process GO:0097285 134 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
developmental process involved in reproduction GO:0003006 159 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
positive regulation of neuron projection development GO:0010976 99 0.019
negative regulation of cell communication GO:0010648 158 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
positive regulation of cell development GO:0010720 176 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
response to inorganic substance GO:0010035 377 0.018
regulation of cellular component movement GO:0051270 150 0.018
response to vitamin GO:0033273 131 0.018
negative regulation of neurogenesis GO:0050768 78 0.018
transmission of nerve impulse GO:0019226 42 0.018
protein homooligomerization GO:0051260 91 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
regulation of system process GO:0044057 208 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
protein phosphorylation GO:0006468 345 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
negative regulation of protein metabolic process GO:0051248 114 0.017
regeneration GO:0031099 163 0.017
cellular response to peptide GO:1901653 133 0.017
reproductive structure development GO:0048608 128 0.017
cellular response to external stimulus GO:0071496 118 0.017
ensheathment of neurons GO:0007272 40 0.017
response to camp GO:0051591 91 0.017
response to mechanical stimulus GO:0009612 134 0.017
Rat
response to oxidative stress GO:0006979 186 0.017
Rat
organ morphogenesis GO:0009887 75 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
cellular homeostasis GO:0019725 252 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
catabolic process GO:0009056 351 0.017
tongue morphogenesis GO:0043587 3 0.016
response to toxic substance GO:0009636 133 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
neuronal action potential GO:0019228 35 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
negative regulation of cell development GO:0010721 82 0.016
regulation of neural precursor cell proliferation GO:2000177 16 0.016
sensory organ development GO:0007423 74 0.016
aging GO:0007568 241 0.016
Rat
salivary gland morphogenesis GO:0007435 1 0.016
organic acid metabolic process GO:0006082 292 0.016
response to purine containing compound GO:0014074 126 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
response to monosaccharide GO:0034284 159 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
single organism organelle organization GO:1902589 180 0.015
ossification GO:0001503 70 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
plasminogen activation GO:0031639 2 0.015
non canonical wnt signaling pathway GO:0035567 3 0.015
response to corticosteroid GO:0031960 235 0.015
establishment of tissue polarity GO:0007164 2 0.015
epithelial cell differentiation GO:0030855 71 0.015
establishment of protein localization GO:0045184 141 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
cellular response to alcohol GO:0097306 87 0.015
purine nucleoside metabolic process GO:0042278 169 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
axon development GO:0061564 96 0.014
organophosphate metabolic process GO:0019637 370 0.014
glycosaminoglycan biosynthetic process GO:0006024 4 0.014
cell morphogenesis GO:0000902 142 0.014
vascular process in circulatory system GO:0003018 96 0.014
metestrus GO:0060210 1 0.014
response to growth factor GO:0070848 189 0.014
vesicle mediated transport GO:0016192 181 0.014
regulation of blood circulation GO:1903522 110 0.014
circulatory system process GO:0003013 183 0.014
synaptic transmission GO:0007268 235 0.014
response to glucose GO:0009749 136 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
growth GO:0040007 165 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
organic substance catabolic process GO:1901575 316 0.013
response to increased oxygen levels GO:0036296 45 0.013
response to ketone GO:1901654 182 0.013
response to ethanol GO:0045471 162 0.013
neurological system process GO:0050877 219 0.013
mesoderm development GO:0007498 2 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
circadian rhythm GO:0007623 88 0.013
regulation of locomotion GO:0040012 148 0.013
nucleoside metabolic process GO:0009116 179 0.013
neurotransmitter uptake GO:0001504 3 0.013
response to hyperoxia GO:0055093 45 0.013
multicellular organism growth GO:0035264 1 0.013
male gamete generation GO:0048232 99 0.013
reproductive system development GO:0061458 128 0.013
osteoblast differentiation GO:0001649 26 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
carboxylic acid biosynthetic process GO:0046394 83 0.012
positive regulation of signal transduction GO:0009967 175 0.012
regulation of establishment of planar polarity GO:0090175 2 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
amine metabolic process GO:0009308 38 0.012
response to external biotic stimulus GO:0043207 221 0.012
Rat
kidney development GO:0001822 67 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
cellular catabolic process GO:0044248 295 0.012
cellular response to stress GO:0033554 269 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of signaling GO:0023056 270 0.012
limb morphogenesis GO:0035108 4 0.012
embryonic skeletal system development GO:0048706 3 0.012
protein complex subunit organization GO:0071822 302 0.012
negative regulation of nervous system development GO:0051961 79 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
lung development GO:0030324 43 0.012
embryonic skeletal system morphogenesis GO:0048704 3 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
negative regulation of cell death GO:0060548 229 0.012
ras protein signal transduction GO:0007265 29 0.012
programmed cell death GO:0012501 392 0.012
regulation of angiogenesis GO:0045765 39 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
neuron projection morphogenesis GO:0048812 122 0.012
response to glucocorticoid GO:0051384 223 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
response to activity GO:0014823 73 0.012
regulation of protein modification process GO:0031399 194 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
intracellular transport GO:0046907 185 0.011
regulation of kinase activity GO:0043549 117 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of molecular function GO:0044093 230 0.011
ion transmembrane transport GO:0034220 365 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
response to calcium ion GO:0051592 59 0.011
regulation of peptidase activity GO:0052547 55 0.011
intracellular protein transport GO:0006886 79 0.011
regulation of synaptic transmission GO:0050804 141 0.011
positive regulation of gamma aminobutyric acid secretion GO:0014054 4 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
negative regulation of signal transduction GO:0009968 83 0.011
renal system development GO:0072001 67 0.011
prostate gland epithelium morphogenesis GO:0060740 2 0.011
response to other organism GO:0051707 220 0.011
Rat
regulation of tube size GO:0035150 89 0.011
blood circulation GO:0008015 183 0.011
response to insulin GO:0032868 133 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
cellular response to fluid shear stress GO:0071498 4 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of endocytosis GO:0030100 42 0.011
choline transport GO:0015871 4 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
response to cytokine GO:0034097 215 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
endocytosis GO:0006897 84 0.011
eye morphogenesis GO:0048592 4 0.011
positive regulation of endothelial cell migration GO:0010595 4 0.010
cellular amide metabolic process GO:0043603 44 0.010
cytoplasmic transport GO:0016482 115 0.010
defense response GO:0006952 194 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
gliogenesis GO:0042063 93 0.010
regulation of proteolysis GO:0030162 66 0.010
inner ear morphogenesis GO:0042472 1 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
cellular response to cgmp GO:0071321 2 0.010
meiotic cell cycle process GO:1903046 3 0.010
learning or memory GO:0007611 90 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
feeding behavior GO:0007631 53 0.010
cognition GO:0050890 92 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010

Epx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.039
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.039
retinal disease DOID:5679 0 0.024
eye and adnexa disease DOID:1492 0 0.024
eye disease DOID:5614 0 0.024
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
disease of metabolism DOID:0014667 0 0.010