Rattus norvegicus

79 known processes

Epo

erythropoietin

Epo biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient levels GO:0031667 370 0.473
regulation of ion transport GO:0043269 245 0.415
cellular response to oxygen containing compound GO:1901701 386 0.406
programmed cell death GO:0012501 392 0.379
response to biotic stimulus GO:0009607 226 0.365
response to lipopolysaccharide GO:0032496 191 0.313
positive regulation of transport GO:0051050 245 0.288
lipid metabolic process GO:0006629 283 0.275
cellular response to lipid GO:0071396 201 0.272
regulation of cell proliferation GO:0042127 359 0.270
synaptic transmission GO:0007268 235 0.264
regulation of neurogenesis GO:0050767 247 0.248
cellular response to hormone stimulus GO:0032870 247 0.227
cellular homeostasis GO:0019725 252 0.225
metal ion transport GO:0030001 289 0.221
regulation of cell development GO:0060284 263 0.219
response to molecule of bacterial origin GO:0002237 194 0.218
regulation of behavior GO:0050795 61 0.211
response to extracellular stimulus GO:0009991 380 0.210
cellular response to endogenous stimulus GO:0071495 377 0.197
response to wounding GO:0009611 254 0.190
response to bacterium GO:0009617 200 0.178
response to purine containing compound GO:0014074 126 0.173
regulation of cellular component organization GO:0051128 368 0.170
neurological system process GO:0050877 219 0.166
regulation of nucleic acid templated transcription GO:1903506 380 0.165
regulation of hormone levels GO:0010817 187 0.164
response to estradiol GO:0032355 164 0.163
apoptotic process GO:0006915 381 0.162
positive regulation of biosynthetic process GO:0009891 319 0.158
regulation of multicellular organismal development GO:2000026 376 0.156
positive regulation of nervous system development GO:0051962 178 0.149
transmembrane transport GO:0055085 412 0.148
cation transport GO:0006812 382 0.144
cell cell signaling GO:0007267 335 0.135
response to carbohydrate GO:0009743 183 0.133
divalent inorganic cation homeostasis GO:0072507 165 0.128
cellular response to steroid hormone stimulus GO:0071383 93 0.128
protein complex biogenesis GO:0070271 263 0.124
response to glucocorticoid GO:0051384 223 0.120
positive regulation of multicellular organismal process GO:0051240 387 0.119
ion homeostasis GO:0050801 212 0.118
regulation of rna metabolic process GO:0051252 391 0.115
ion transmembrane transport GO:0034220 365 0.114
response to organophosphorus GO:0046683 102 0.113
response to peptide GO:1901652 292 0.111
transcription dna templated GO:0006351 377 0.111
response to corticosteroid GO:0031960 235 0.110
response to acid chemical GO:0001101 222 0.108
regulation of programmed cell death GO:0043067 341 0.104
cellular cation homeostasis GO:0030003 180 0.100
response to monosaccharide GO:0034284 159 0.100
positive regulation of neurogenesis GO:0050769 165 0.100
neuron differentiation GO:0030182 368 0.100
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.100
positive regulation of cell death GO:0010942 184 0.095
positive regulation of cell development GO:0010720 176 0.093
signal release GO:0023061 145 0.091
multicellular organism reproduction GO:0032504 233 0.090
regulation of cellular localization GO:0060341 263 0.087
positive regulation of apoptotic process GO:0043065 154 0.084
regulation of rna biosynthetic process GO:2001141 381 0.083
positive regulation of rna biosynthetic process GO:1902680 197 0.080
secretion GO:0046903 307 0.080
cellular response to organic cyclic compound GO:0071407 202 0.080
nucleic acid templated transcription GO:0097659 379 0.079
regulation of apoptotic process GO:0042981 335 0.078
reproduction GO:0000003 245 0.078
regulation of metal ion transport GO:0010959 118 0.075
nitrogen compound transport GO:0071705 229 0.075
cellular ion homeostasis GO:0006873 184 0.074
aging GO:0007568 241 0.074
reproductive process GO:0022414 372 0.072
response to nutrient GO:0007584 248 0.071
growth GO:0040007 165 0.071
response to ethanol GO:0045471 162 0.070
response to hexose GO:0009746 144 0.069
response to estrogen GO:0043627 232 0.069
positive regulation of transcription dna templated GO:0045893 197 0.068
multi organism reproductive process GO:0044703 262 0.068
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.067
positive regulation of gene expression GO:0010628 244 0.067
positive regulation of cell proliferation GO:0008284 249 0.067
central nervous system development GO:0007417 311 0.067
cation homeostasis GO:0055080 195 0.066
brain development GO:0007420 247 0.066
tissue development GO:0009888 252 0.065
cytosolic calcium ion homeostasis GO:0051480 140 0.065
macromolecular complex subunit organization GO:0043933 339 0.062
secretion by cell GO:0032940 248 0.061
chemical homeostasis GO:0048878 292 0.059
neuron projection development GO:0031175 273 0.059
negative regulation of response to stimulus GO:0048585 155 0.059
neuron development GO:0048666 286 0.058
multicellular organismal response to stress GO:0033555 25 0.058
cell motility GO:0048870 202 0.057
positive regulation of cellular biosynthetic process GO:0031328 295 0.056
cellular chemical homeostasis GO:0055082 247 0.056
cellular divalent inorganic cation homeostasis GO:0072503 162 0.056
regulation of transcription dna templated GO:0006355 374 0.054
response to decreased oxygen levels GO:0036293 237 0.054
cellular response to nitrogen compound GO:1901699 210 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.053
cellular response to stress GO:0033554 269 0.053
negative regulation of gene expression GO:0010629 199 0.052
regulation of response to wounding GO:1903034 69 0.051
inorganic ion transmembrane transport GO:0098660 229 0.050
response to camp GO:0051591 91 0.050
rna biosynthetic process GO:0032774 380 0.050
tube development GO:0035295 89 0.050
behavior GO:0007610 205 0.049
circadian rhythm GO:0007623 88 0.049
regulation of phosphate metabolic process GO:0019220 349 0.048
multicellular organismal reproductive process GO:0048609 233 0.048
cyclic nucleotide metabolic process GO:0009187 80 0.048
regulation of synaptic transmission GO:0050804 141 0.048
regulation of nervous system development GO:0051960 264 0.047
glutamate receptor signaling pathway GO:0007215 43 0.047
sexual reproduction GO:0019953 148 0.047
positive regulation of nucleic acid templated transcription GO:1903508 197 0.046
peptide secretion GO:0002790 86 0.046
anion transport GO:0006820 178 0.046
muscle contraction GO:0006936 88 0.045
positive regulation of signaling GO:0023056 270 0.045
rhythmic process GO:0048511 156 0.045
calcium ion homeostasis GO:0055074 162 0.045
response to glucose GO:0009749 136 0.044
cell projection organization GO:0030030 302 0.044
positive regulation of secretion GO:0051047 140 0.044
protein heterooligomerization GO:0051291 89 0.044
cation transmembrane transport GO:0098655 263 0.043
localization of cell GO:0051674 202 0.043
response to inorganic substance GO:0010035 377 0.043
regulation of system process GO:0044057 208 0.042
metal ion homeostasis GO:0055065 186 0.042
regulation of membrane potential GO:0042391 110 0.042
regulation of cell differentiation GO:0045595 320 0.042
protein oligomerization GO:0051259 191 0.041
homeostatic process GO:0042592 331 0.041
regulation of phosphorus metabolic process GO:0051174 349 0.041
response to hypoxia GO:0001666 231 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.041
calcium ion transport GO:0006816 131 0.041
response to peptide hormone GO:0043434 278 0.040
cellular response to organonitrogen compound GO:0071417 197 0.040
cellular response to glucocorticoid stimulus GO:0071385 68 0.040
negative regulation of metabolic process GO:0009892 331 0.040
cellular component movement GO:0006928 248 0.040
regulation of camp biosynthetic process GO:0030817 38 0.039
cellular response to external stimulus GO:0071496 118 0.038
single organism biosynthetic process GO:0044711 342 0.038
response to insulin GO:0032868 133 0.038
reproductive system development GO:0061458 128 0.038
divalent metal ion transport GO:0070838 132 0.038
positive regulation of developmental process GO:0051094 283 0.038
cellular response to alcohol GO:0097306 87 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.037
positive regulation of behavior GO:0048520 38 0.036
salivary gland development GO:0007431 3 0.036
positive regulation of cell differentiation GO:0045597 217 0.036
organic acid transport GO:0015849 116 0.036
regulation of secretion GO:0051046 224 0.035
rna metabolic process GO:0016070 406 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
cell activation GO:0001775 97 0.034
response to radiation GO:0009314 137 0.034
neuropeptide signaling pathway GO:0007218 29 0.034
cellular component biogenesis GO:0044085 368 0.034
hormone transport GO:0009914 121 0.034
head development GO:0060322 247 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.033
protein complex assembly GO:0006461 263 0.032
positive regulation of locomotion GO:0040017 102 0.032
cellular response to growth factor stimulus GO:0071363 162 0.032
regulation of neuron differentiation GO:0045664 208 0.032
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.031
sensory perception GO:0007600 101 0.031
regulation of neuron death GO:1901214 115 0.031
regulation of peptide hormone secretion GO:0090276 80 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
positive regulation of rna metabolic process GO:0051254 203 0.030
response to light stimulus GO:0009416 52 0.030
cellular response to hexose stimulus GO:0071331 65 0.030
negative regulation of programmed cell death GO:0043069 183 0.030
gland development GO:0048732 155 0.030
regulation of secretion by cell GO:1903530 208 0.030
positive regulation of programmed cell death GO:0043068 157 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
regulation of peptide secretion GO:0002791 82 0.029
response to other organism GO:0051707 220 0.028
myeloid leukocyte activation GO:0002274 36 0.028
cellular response to interleukin 6 GO:0071354 9 0.028
nucleoside phosphate biosynthetic process GO:1901293 102 0.028
organic acid metabolic process GO:0006082 292 0.028
cell type specific apoptotic process GO:0097285 134 0.028
regulation of chemotaxis GO:0050920 29 0.027
oxoacid metabolic process GO:0043436 290 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
locomotion GO:0040011 237 0.027
sensory organ development GO:0007423 74 0.027
hormone secretion GO:0046879 115 0.027
regeneration GO:0031099 163 0.026
neuron apoptotic process GO:0051402 88 0.026
neuron death GO:0070997 127 0.026
regulation of phosphorylation GO:0042325 248 0.026
negative regulation of cell proliferation GO:0008285 119 0.026
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.026
regulation of cell projection organization GO:0031344 175 0.026
wound healing GO:0042060 122 0.026
regulation of neuron projection development GO:0010975 161 0.026
cellular response to peptide hormone stimulus GO:0071375 120 0.026
regulation of cellular component movement GO:0051270 150 0.026
anion transmembrane transport GO:0098656 77 0.026
response to oxidative stress GO:0006979 186 0.025
ovulation cycle GO:0042698 67 0.025
regulation of dendrite development GO:0050773 59 0.025
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.024
developmental growth GO:0048589 100 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
positive regulation of neuron differentiation GO:0045666 126 0.024
cellular response to extracellular stimulus GO:0031668 73 0.024
protein complex subunit organization GO:0071822 302 0.024
response to axon injury GO:0048678 59 0.023
regulation of catalytic activity GO:0050790 304 0.023
inflammatory response to antigenic stimulus GO:0002437 18 0.023
response to calcium ion GO:0051592 59 0.023
response to transition metal nanoparticle GO:1990267 122 0.023
monovalent inorganic cation transport GO:0015672 172 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
regulation of cell motility GO:2000145 131 0.022
organic anion transport GO:0015711 132 0.022
spermatogenesis GO:0007283 99 0.022
signal transduction by phosphorylation GO:0023014 144 0.022
positive regulation of molecular function GO:0044093 230 0.022
macromolecular complex assembly GO:0065003 273 0.022
positive regulation of secretion by cell GO:1903532 128 0.022
leukocyte activation GO:0045321 76 0.022
divalent inorganic cation transport GO:0072511 134 0.022
forebrain development GO:0030900 98 0.022
gamete generation GO:0007276 124 0.022
ribonucleotide biosynthetic process GO:0009260 85 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
response to fatty acid GO:0070542 65 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
muscle system process GO:0003012 115 0.021
regulation of blood circulation GO:1903522 110 0.021
lipid biosynthetic process GO:0008610 128 0.021
insulin secretion GO:0030073 69 0.021
response to starvation GO:0042594 59 0.021
cardiac conduction GO:0061337 2 0.021
cyclic purine nucleotide metabolic process GO:0052652 62 0.021
cell growth GO:0016049 104 0.021
saliva secretion GO:0046541 3 0.021
single organism reproductive process GO:0044702 297 0.020
regulation of ion transmembrane transporter activity GO:0032412 48 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
response to cytokine GO:0034097 215 0.020
positive regulation of peptide hormone secretion GO:0090277 50 0.020
proteolysis GO:0006508 175 0.020
cellular response to drug GO:0035690 30 0.020
heart contraction GO:0060047 57 0.020
circulatory system development GO:0072359 134 0.020
cell migration GO:0016477 197 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
regulation of muscle system process GO:0090257 79 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
peptide hormone secretion GO:0030072 84 0.019
glucose homeostasis GO:0042593 75 0.019
thyroid gland development GO:0030878 1 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
acid secretion GO:0046717 48 0.019
cellular component assembly GO:0022607 360 0.019
activation of protein kinase activity GO:0032147 47 0.019
negative regulation of cell death GO:0060548 229 0.018
response to hyperoxia GO:0055093 45 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
response to mineralocorticoid GO:0051385 49 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
vesicle mediated transport GO:0016192 181 0.018
activation of janus kinase activity GO:0042976 5 0.018
response to external biotic stimulus GO:0043207 221 0.018
regulation of calcium ion transport GO:0051924 77 0.018
carboxylic acid transport GO:0046942 115 0.018
establishment of organelle localization GO:0051656 37 0.018
ribose phosphate biosynthetic process GO:0046390 87 0.017
organic hydroxy compound metabolic process GO:1901615 115 0.017
hepaticobiliary system development GO:0061008 90 0.017
negative regulation of phosphorus metabolic process GO:0010563 80 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
motor neuron axon guidance GO:0008045 1 0.017
lung development GO:0030324 43 0.017
response to toxic substance GO:0009636 133 0.017
n methyl d aspartate receptor clustering GO:0097114 2 0.017
organ growth GO:0035265 24 0.016
monocarboxylic acid transport GO:0015718 52 0.016
regulation of protein metabolic process GO:0051246 289 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
cellular response to estradiol stimulus GO:0071392 16 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
response to prostaglandin f GO:0034696 4 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
female pregnancy GO:0007565 122 0.015
phasic smooth muscle contraction GO:0014821 3 0.015
negative regulation of signaling GO:0023057 157 0.015
cellular response to lipopolysaccharide GO:0071222 55 0.015
telencephalon development GO:0021537 62 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
epithelium development GO:0060429 96 0.015
regulation of response to stress GO:0080134 126 0.015
negative regulation of cell projection organization GO:0031345 50 0.015
cellular amine metabolic process GO:0044106 38 0.015
peptide transport GO:0015833 97 0.015
regulation of anatomical structure size GO:0090066 135 0.015
regulation of response to external stimulus GO:0032101 106 0.015
visual perception GO:0007601 3 0.015
oxidation reduction process GO:0055114 304 0.014
inflammatory response GO:0006954 150 0.014
drinking behavior GO:0042756 11 0.014
male gamete generation GO:0048232 99 0.014
regulation of locomotion GO:0040012 148 0.014
purine ribonucleotide biosynthetic process GO:0009152 81 0.014
epithelial cell differentiation GO:0030855 71 0.014
response to hydrogen peroxide GO:0042542 89 0.014
organophosphate metabolic process GO:0019637 370 0.014
regulation of glutamate secretion GO:0014048 17 0.014
negative regulation of neuron death GO:1901215 69 0.014
striated muscle contraction GO:0006941 44 0.014
regulation of tube size GO:0035150 89 0.014
regulation of saliva secretion GO:0046877 3 0.014
regulation of insulin secretion GO:0050796 65 0.014
regulation of vasculature development GO:1901342 44 0.014
metanephric tubule morphogenesis GO:0072173 2 0.014
acute inflammatory response GO:0002526 58 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.014
response to growth factor GO:0070848 189 0.013
regulation of transmembrane transporter activity GO:0022898 49 0.013
cellular lipid metabolic process GO:0044255 208 0.013
intracellular signal transduction GO:0035556 314 0.013
regulation of feeding behavior GO:0060259 14 0.013
catabolic process GO:0009056 351 0.013
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
positive regulation of ion transport GO:0043270 94 0.013
regulation of cell growth GO:0001558 85 0.013
cellular response to carbohydrate stimulus GO:0071322 72 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
long term synaptic potentiation GO:0060291 21 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
cellular ketone metabolic process GO:0042180 51 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
regulation of cell migration GO:0030334 128 0.013
response to oxygen levels GO:0070482 265 0.013
positive regulation of biomineral tissue development GO:0070169 4 0.013
carbohydrate homeostasis GO:0033500 75 0.013
negative regulation of molecular function GO:0044092 133 0.013
action potential GO:0001508 54 0.013
response to alkaloid GO:0043279 132 0.013
cyclic nucleotide biosynthetic process GO:0009190 63 0.012
positive regulation of cell migration GO:0030335 96 0.012
urogenital system development GO:0001655 78 0.012
response to ionizing radiation GO:0010212 59 0.012
cellular response to oxidative stress GO:0034599 76 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
positive regulation of leukocyte migration GO:0002687 21 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
protein phosphorylation GO:0006468 345 0.012
muscle structure development GO:0061061 87 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
sex differentiation GO:0007548 113 0.012
nucleotide metabolic process GO:0009117 279 0.012
body fluid secretion GO:0007589 41 0.012
small molecule catabolic process GO:0044282 59 0.012
somatostatin receptor signaling pathway GO:0038169 4 0.012
positive regulation of calcium ion transport GO:0051928 36 0.012
sensory perception of light stimulus GO:0050953 3 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
locomotory exploration behavior GO:0035641 1 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
cellular response to glucose stimulus GO:0071333 65 0.011
taxis GO:0042330 67 0.011
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.011
circulatory system process GO:0003013 183 0.011
positive regulation of response to food GO:0032097 3 0.011
single organism organelle organization GO:1902589 180 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
neuron migration GO:0001764 21 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
ossification GO:0001503 70 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
biological adhesion GO:0022610 110 0.011
cell chemotaxis GO:0060326 31 0.011
regulation of signal transduction GO:0009966 318 0.011
defense response GO:0006952 194 0.011
regulation of ossification GO:0030278 32 0.011
response to progesterone GO:0032570 48 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
cellular response to monosaccharide stimulus GO:0071326 67 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
regulation of muscle contraction GO:0006937 53 0.010
acute inflammatory response to antigenic stimulus GO:0002438 9 0.010
lipid transport GO:0006869 61 0.010
membrane depolarization GO:0051899 32 0.010
negative regulation of chronic inflammatory response GO:0002677 2 0.010
small molecule biosynthetic process GO:0044283 124 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
regulation of epithelial cell proliferation GO:0050678 49 0.010
positive regulation of peptide secretion GO:0002793 52 0.010
cellular response to peptide GO:1901653 133 0.010
exploration behavior GO:0035640 1 0.010
actin filament based process GO:0030029 86 0.010
myeloid cell activation involved in immune response GO:0002275 13 0.010
maternal process involved in female pregnancy GO:0060135 38 0.010
amine metabolic process GO:0009308 38 0.010
negative regulation of developmental process GO:0051093 125 0.010
negative regulation of nervous system development GO:0051961 79 0.010
s shaped body morphogenesis GO:0072050 2 0.010
negative regulation of protein processing GO:0010955 47 0.010

Epo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
kidney disease DOID:557 0 0.035
disease of anatomical entity DOID:7 0 0.035
urinary system disease DOID:18 0 0.035
substance related disorder DOID:303 0 0.024
disease of mental health DOID:150 0 0.024