Rattus norvegicus

0 known processes

LOC500876

LOC500876

LOC500876 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.051
carboxylic acid metabolic process GO:0019752 289 0.044
oxoacid metabolic process GO:0043436 290 0.040
neuron differentiation GO:0030182 368 0.033
response to inorganic substance GO:0010035 377 0.032
response to nutrient levels GO:0031667 370 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
cellular component assembly GO:0022607 360 0.031
reproductive process GO:0022414 372 0.031
response to extracellular stimulus GO:0009991 380 0.031
regulation of cell proliferation GO:0042127 359 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
cellular response to oxygen containing compound GO:1901701 386 0.030
regulation of cell differentiation GO:0045595 320 0.029
head development GO:0060322 247 0.029
amine metabolic process GO:0009308 38 0.029
single organism biosynthetic process GO:0044711 342 0.029
regulation of molecular function GO:0065009 398 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
homeostatic process GO:0042592 331 0.028
apoptotic process GO:0006915 381 0.028
single organism reproductive process GO:0044702 297 0.028
rna metabolic process GO:0016070 406 0.028
brain development GO:0007420 247 0.028
cellular ketone metabolic process GO:0042180 51 0.028
cellular homeostasis GO:0019725 252 0.027
cellular component biogenesis GO:0044085 368 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
cellular amine metabolic process GO:0044106 38 0.027
chemical homeostasis GO:0048878 292 0.027
transmembrane transport GO:0055085 412 0.026
negative regulation of metabolic process GO:0009892 331 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
regulation of rna biosynthetic process GO:2001141 381 0.025
regulation of catalytic activity GO:0050790 304 0.025
catabolic process GO:0009056 351 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
central nervous system development GO:0007417 311 0.025
lipid metabolic process GO:0006629 283 0.024
ion transmembrane transport GO:0034220 365 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
positive regulation of developmental process GO:0051094 283 0.024
regulation of programmed cell death GO:0043067 341 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
response to oxygen levels GO:0070482 265 0.024
regulation of neurogenesis GO:0050767 247 0.024
response to metal ion GO:0010038 253 0.024
regulation of apoptotic process GO:0042981 335 0.024
rna biosynthetic process GO:0032774 380 0.023
regulation of rna metabolic process GO:0051252 391 0.023
multi organism reproductive process GO:0044703 262 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
cation transport GO:0006812 382 0.023
regulation of transcription dna templated GO:0006355 374 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
regulation of cell development GO:0060284 263 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
metal ion transport GO:0030001 289 0.022
protein complex subunit organization GO:0071822 302 0.022
reproduction GO:0000003 245 0.022
multicellular organism reproduction GO:0032504 233 0.022
secretion GO:0046903 307 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
cellular response to stress GO:0033554 269 0.022
protein complex biogenesis GO:0070271 263 0.022
regulation of nervous system development GO:0051960 264 0.022
programmed cell death GO:0012501 392 0.022
macromolecular complex assembly GO:0065003 273 0.022
response to hypoxia GO:0001666 231 0.022
transcription dna templated GO:0006351 377 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
regulation of cellular component organization GO:0051128 368 0.021
regulation of neuron differentiation GO:0045664 208 0.021
neurological system process GO:0050877 219 0.021
secretion by cell GO:0032940 248 0.021
ion homeostasis GO:0050801 212 0.021
single organism catabolic process GO:0044712 283 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
protein complex assembly GO:0006461 263 0.021
neuron development GO:0048666 286 0.021
regulation of cellular localization GO:0060341 263 0.021
response to peptide hormone GO:0043434 278 0.021
response to corticosteroid GO:0031960 235 0.021
regulation of protein metabolic process GO:0051246 289 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
cellular catabolic process GO:0044248 295 0.021
cellular chemical homeostasis GO:0055082 247 0.021
nucleic acid templated transcription GO:0097659 379 0.021
positive regulation of molecular function GO:0044093 230 0.020
neuron projection development GO:0031175 273 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
response to estrogen GO:0043627 232 0.020
organophosphate metabolic process GO:0019637 370 0.020
aging GO:0007568 241 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
protein phosphorylation GO:0006468 345 0.020
intracellular signal transduction GO:0035556 314 0.020
response to decreased oxygen levels GO:0036293 237 0.020
cell cell signaling GO:0007267 335 0.020
cell projection organization GO:0030030 302 0.020
response to peptide GO:1901652 292 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
regulation of hormone levels GO:0010817 187 0.019
response to nutrient GO:0007584 248 0.019
regulation of system process GO:0044057 208 0.019
negative regulation of cell death GO:0060548 229 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
cellular lipid metabolic process GO:0044255 208 0.019
nitrogen compound transport GO:0071705 229 0.019
organic substance catabolic process GO:1901575 316 0.018
regulation of secretion by cell GO:1903530 208 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
response to acid chemical GO:0001101 222 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
positive regulation of gene expression GO:0010628 244 0.018
response to glucocorticoid GO:0051384 223 0.018
anion transport GO:0006820 178 0.018
response to carbohydrate GO:0009743 183 0.018
response to monosaccharide GO:0034284 159 0.017
regulation of phosphorylation GO:0042325 248 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
cation transmembrane transport GO:0098655 263 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
regulation of cell projection organization GO:0031344 175 0.017
response to bacterium GO:0009617 200 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
oxidation reduction process GO:0055114 304 0.017
regulation of signal transduction GO:0009966 318 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
response to ketone GO:1901654 182 0.017
proteolysis GO:0006508 175 0.017
cellular component movement GO:0006928 248 0.017
behavior GO:0007610 205 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
metal ion homeostasis GO:0055065 186 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
nucleotide metabolic process GO:0009117 279 0.016
cation homeostasis GO:0055080 195 0.016
regulation of secretion GO:0051046 224 0.016
response to hexose GO:0009746 144 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
purine containing compound metabolic process GO:0072521 253 0.016
response to other organism GO:0051707 220 0.016
blood circulation GO:0008015 183 0.016
anterior posterior pattern specification GO:0009952 1 0.016
macromolecule localization GO:0033036 252 0.016
response to external biotic stimulus GO:0043207 221 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
protein oligomerization GO:0051259 191 0.016
cellular response to lipid GO:0071396 201 0.016
rhythmic process GO:0048511 156 0.016
heart morphogenesis GO:0003007 3 0.016
defense response GO:0006952 194 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
positive regulation of transport GO:0051050 245 0.016
response to ethanol GO:0045471 162 0.016
cellular ion homeostasis GO:0006873 184 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.015
cellular cation homeostasis GO:0030003 180 0.015
response to glucose GO:0009749 136 0.015
response to growth factor GO:0070848 189 0.015
regulation of neuron projection development GO:0010975 161 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
synaptic transmission GO:0007268 235 0.015
positive regulation of cell development GO:0010720 176 0.015
calcium ion homeostasis GO:0055074 162 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
circulatory system process GO:0003013 183 0.015
negative regulation of cell communication GO:0010648 158 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
negative regulation of gene expression GO:0010629 199 0.015
response to estradiol GO:0032355 164 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
response to lipopolysaccharide GO:0032496 191 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
developmental process involved in reproduction GO:0003006 159 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
organic acid biosynthetic process GO:0016053 83 0.014
positive regulation of cell communication GO:0010647 271 0.014
sexual reproduction GO:0019953 148 0.014
response to wounding GO:0009611 254 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
regulation of membrane potential GO:0042391 110 0.014
multi multicellular organism process GO:0044706 138 0.014
positive regulation of nervous system development GO:0051962 178 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
intracellular transport GO:0046907 185 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
tissue development GO:0009888 252 0.014
positive regulation of cell death GO:0010942 184 0.014
organelle organization GO:0006996 266 0.014
gastrulation GO:0007369 2 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
axis specification GO:0009798 4 0.014
regulation of hydrolase activity GO:0051336 143 0.014
divalent inorganic cation transport GO:0072511 134 0.014
response to oxidative stress GO:0006979 186 0.014
response to biotic stimulus GO:0009607 226 0.014
cell motility GO:0048870 202 0.014
positive regulation of signaling GO:0023056 270 0.013
reproductive structure development GO:0048608 128 0.013
protein localization GO:0008104 191 0.013
cell migration GO:0016477 197 0.013
calcium ion transport GO:0006816 131 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
regeneration GO:0031099 163 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
small molecule biosynthetic process GO:0044283 124 0.013
signal release GO:0023061 145 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
reproductive system development GO:0061458 128 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
female pregnancy GO:0007565 122 0.013
response to cytokine GO:0034097 215 0.013
negative regulation of molecular function GO:0044092 133 0.013
localization of cell GO:0051674 202 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
ras protein signal transduction GO:0007265 29 0.013
cardiovascular system development GO:0072358 134 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
nucleoside metabolic process GO:0009116 179 0.013
gamete generation GO:0007276 124 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
single organism intracellular transport GO:1902582 166 0.013
regulation of protein modification process GO:0031399 194 0.013
divalent metal ion transport GO:0070838 132 0.013
locomotion GO:0040011 237 0.013
fatty acid metabolic process GO:0006631 99 0.013
response to vitamin GO:0033273 131 0.013
growth GO:0040007 165 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
mesoderm development GO:0007498 2 0.013
regulation of protein phosphorylation GO:0001932 183 0.012
heterocycle catabolic process GO:0046700 167 0.012
negative regulation of transport GO:0051051 136 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
regulation of synaptic transmission GO:0050804 141 0.012
cofactor metabolic process GO:0051186 95 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
positive regulation of protein modification process GO:0031401 142 0.012
circulatory system development GO:0072359 134 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
response to mechanical stimulus GO:0009612 134 0.012
hormone secretion GO:0046879 115 0.012
development of primary sexual characteristics GO:0045137 107 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
chromosome segregation GO:0007059 2 0.012
lipid biosynthetic process GO:0008610 128 0.012
response to alkaloid GO:0043279 132 0.012
appendage morphogenesis GO:0035107 4 0.012
gland development GO:0048732 155 0.012
regulation of ion transport GO:0043269 245 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
response to toxic substance GO:0009636 133 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
establishment of protein localization GO:0045184 141 0.012
regulation of cell migration GO:0030334 128 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
coenzyme metabolic process GO:0006732 86 0.011
immune system process GO:0002376 204 0.011
response to organophosphorus GO:0046683 102 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
response to radiation GO:0009314 137 0.011
cell adhesion GO:0007155 110 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
aromatic compound catabolic process GO:0019439 168 0.011
regulation of immune system process GO:0002682 123 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
embryonic pattern specification GO:0009880 1 0.011
single organism organelle organization GO:1902589 180 0.011
hormone transport GO:0009914 121 0.011
sensory perception GO:0007600 101 0.011
negative regulation of signaling GO:0023057 157 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
organ regeneration GO:0031100 101 0.011
regulation of anatomical structure size GO:0090066 135 0.011
sex differentiation GO:0007548 113 0.011
regulation of metal ion transport GO:0010959 118 0.011
circadian rhythm GO:0007623 88 0.011
amide transport GO:0042886 105 0.011
spermatogenesis GO:0007283 99 0.011
cytoplasmic transport GO:0016482 115 0.011
peptidyl amino acid modification GO:0018193 126 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
cell growth GO:0016049 104 0.011
positive regulation of secretion GO:0051047 140 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
regulation of hormone secretion GO:0046883 106 0.011
limb morphogenesis GO:0035108 4 0.011
regulation of body fluid levels GO:0050878 90 0.011
action potential GO:0001508 54 0.011
sequestering of metal ion GO:0051238 9 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
protein homooligomerization GO:0051260 91 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
regulation of cell motility GO:2000145 131 0.010
cellular response to alcohol GO:0097306 87 0.010
carbohydrate metabolic process GO:0005975 130 0.010
cellular component morphogenesis GO:0032989 155 0.010
transmission of nerve impulse GO:0019226 42 0.010
carboxylic acid transport GO:0046942 115 0.010
response to reactive oxygen species GO:0000302 120 0.010
forebrain development GO:0030900 98 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
gonad development GO:0008406 104 0.010
muscle system process GO:0003012 115 0.010
male gamete generation GO:0048232 99 0.010
cell morphogenesis GO:0000902 142 0.010
peptide transport GO:0015833 97 0.010
single organism behavior GO:0044708 130 0.010
regulation of kinase activity GO:0043549 117 0.010
lipid storage GO:0019915 1 0.010
regulation of cellular component movement GO:0051270 150 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
organic anion transport GO:0015711 132 0.010
negative regulation of innate immune response GO:0045824 4 0.010
organic acid transport GO:0015849 116 0.010
immune response GO:0006955 104 0.010
purine nucleoside metabolic process GO:0042278 169 0.010

LOC500876 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
sensory system disease DOID:0050155 0 0.018
retinal disease DOID:5679 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.014
central nervous system disease DOID:331 0 0.010