Rattus norvegicus

0 known processes

Hook1

hook homolog 1 (Drosophila)

Hook1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of multicellular organismal development GO:2000026 376 0.118
cellular amine metabolic process GO:0044106 38 0.070
oxoacid metabolic process GO:0043436 290 0.065
amine metabolic process GO:0009308 38 0.061
protein complex biogenesis GO:0070271 263 0.052
negative regulation of metabolic process GO:0009892 331 0.048
cellular lipid metabolic process GO:0044255 208 0.047
regulation of phosphate metabolic process GO:0019220 349 0.043
transcription from rna polymerase ii promoter GO:0006366 252 0.042
regulation of rna biosynthetic process GO:2001141 381 0.041
neuron projection development GO:0031175 273 0.040
cellular amino acid metabolic process GO:0006520 107 0.040
neuron development GO:0048666 286 0.037
cellular chemical homeostasis GO:0055082 247 0.037
homeostatic process GO:0042592 331 0.035
organophosphate biosynthetic process GO:0090407 143 0.035
single organism biosynthetic process GO:0044711 342 0.034
regulation of rna metabolic process GO:0051252 391 0.034
organic acid metabolic process GO:0006082 292 0.034
macromolecular complex subunit organization GO:0043933 339 0.034
protein complex subunit organization GO:0071822 302 0.033
regulation of programmed cell death GO:0043067 341 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
neuron differentiation GO:0030182 368 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.031
regulation of cellular component organization GO:0051128 368 0.031
positive regulation of cellular amine metabolic process GO:0033240 3 0.030
regulation of transcription dna templated GO:0006355 374 0.030
rna biosynthetic process GO:0032774 380 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.030
cell projection organization GO:0030030 302 0.029
regulation of proteasomal protein catabolic process GO:0061136 4 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
positive regulation of cellular component organization GO:0051130 200 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
response to nutrient levels GO:0031667 370 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
regulation of phosphorylation GO:0042325 248 0.027
cellular homeostasis GO:0019725 252 0.026
vesicle mediated transport GO:0016192 181 0.026
Human
cellular component assembly GO:0022607 360 0.026
cellular ketone metabolic process GO:0042180 51 0.026
positive regulation of developmental process GO:0051094 283 0.026
response to acid chemical GO:0001101 222 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
negative regulation of cell death GO:0060548 229 0.025
nucleic acid templated transcription GO:0097659 379 0.025
transmembrane transport GO:0055085 412 0.025
transcription dna templated GO:0006351 377 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
protein complex assembly GO:0006461 263 0.024
chemical homeostasis GO:0048878 292 0.024
regulation of cellular localization GO:0060341 263 0.024
macromolecular complex assembly GO:0065003 273 0.024
reproductive process GO:0022414 372 0.023
protein oligomerization GO:0051259 191 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
ion homeostasis GO:0050801 212 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
response to biotic stimulus GO:0009607 226 0.023
regulation of cell differentiation GO:0045595 320 0.023
cellular component biogenesis GO:0044085 368 0.022
negative regulation of signaling GO:0023057 157 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
regulation of neurogenesis GO:0050767 247 0.022
lipid biosynthetic process GO:0008610 128 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
response to inorganic substance GO:0010035 377 0.020
response to extracellular stimulus GO:0009991 380 0.020
regulation of signal transduction GO:0009966 318 0.020
response to corticosteroid GO:0031960 235 0.020
cellular cation homeostasis GO:0030003 180 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
protein localization GO:0008104 191 0.020
muscle system process GO:0003012 115 0.020
cell morphogenesis GO:0000902 142 0.020
positive regulation of gene expression GO:0010628 244 0.020
central nervous system development GO:0007417 311 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
reproduction GO:0000003 245 0.019
intracellular signal transduction GO:0035556 314 0.019
response to other organism GO:0051707 220 0.019
organophosphate metabolic process GO:0019637 370 0.018
cell cell signaling GO:0007267 335 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
positive regulation of nervous system development GO:0051962 178 0.018
protein phosphorylation GO:0006468 345 0.018
response to glucocorticoid GO:0051384 223 0.018
proteolysis GO:0006508 175 0.018
nucleotide metabolic process GO:0009117 279 0.018
neuron projection morphogenesis GO:0048812 122 0.018
rna metabolic process GO:0016070 406 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
regulation of nervous system development GO:0051960 264 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
single organism reproductive process GO:0044702 297 0.017
aging GO:0007568 241 0.017
lipid metabolic process GO:0006629 283 0.017
polyamine biosynthetic process GO:0006596 4 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
regulation of immune system process GO:0002682 123 0.017
regulation of cell development GO:0060284 263 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
regulation of cell projection organization GO:0031344 175 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
response to oxygen levels GO:0070482 265 0.016
response to carbohydrate GO:0009743 183 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
regulation of apoptotic process GO:0042981 335 0.016
regulation of membrane potential GO:0042391 110 0.016
response to metal ion GO:0010038 253 0.016
programmed cell death GO:0012501 392 0.016
glycerolipid metabolic process GO:0046486 67 0.015
response to decreased oxygen levels GO:0036293 237 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
response to bacterium GO:0009617 200 0.015
response to vitamin GO:0033273 131 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
ncrna processing GO:0034470 3 0.015
response to toxic substance GO:0009636 133 0.015
gamete generation GO:0007276 124 0.015
multicellular organism reproduction GO:0032504 233 0.014
regulation of neuron differentiation GO:0045664 208 0.014
multi organism reproductive process GO:0044703 262 0.014
positive regulation of transport GO:0051050 245 0.014
response to glucose GO:0009749 136 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
regulation of neuron projection development GO:0010975 161 0.014
coenzyme metabolic process GO:0006732 86 0.014
metal ion transport GO:0030001 289 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
cofactor metabolic process GO:0051186 95 0.013
positive regulation of cell development GO:0010720 176 0.013
nitrogen compound transport GO:0071705 229 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
behavior GO:0007610 205 0.013
jak stat cascade GO:0007259 26 0.013
cellular component morphogenesis GO:0032989 155 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
response to monosaccharide GO:0034284 159 0.013
macromolecule localization GO:0033036 252 0.013
cell part morphogenesis GO:0032990 123 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
gastrulation GO:0007369 2 0.013
negative regulation of molecular function GO:0044092 133 0.012
cytoplasmic transport GO:0016482 115 0.012
Human
eye morphogenesis GO:0048592 4 0.012
amide transport GO:0042886 105 0.012
axon development GO:0061564 96 0.012
cellular response to stress GO:0033554 269 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
response to external biotic stimulus GO:0043207 221 0.012
multi multicellular organism process GO:0044706 138 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
negative regulation of cell communication GO:0010648 158 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
regulation of homeostatic process GO:0032844 101 0.012
ion transmembrane transport GO:0034220 365 0.012
response to growth factor GO:0070848 189 0.012
cellular ion homeostasis GO:0006873 184 0.012
defense response GO:0006952 194 0.011
regulation of system process GO:0044057 208 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
head development GO:0060322 247 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
regulation of neuron death GO:1901214 115 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
response to nutrient GO:0007584 248 0.011
dendrite development GO:0016358 72 0.011
tissue development GO:0009888 252 0.011
gland development GO:0048732 155 0.011
biological adhesion GO:0022610 110 0.011
purine containing compound metabolic process GO:0072521 253 0.011
multicellular organism growth GO:0035264 1 0.011
secretion GO:0046903 307 0.011
response to acetate GO:0010034 3 0.011
regulation of mitotic sister chromatid segregation GO:0033047 1 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
response to ethanol GO:0045471 162 0.010
neuron death GO:0070997 127 0.010
peptidyl amino acid modification GO:0018193 126 0.010
cellular macromolecule localization GO:0070727 122 0.010
brain development GO:0007420 247 0.010
cytokinetic process GO:0032506 1 0.010
ras protein signal transduction GO:0007265 29 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
rhythmic process GO:0048511 156 0.010
response to hexose GO:0009746 144 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
anion transport GO:0006820 178 0.010

Hook1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
central nervous system disease DOID:331 0 0.012
disease of metabolism DOID:0014667 0 0.011