Rattus norvegicus

96 known processes

Stat6

signal transducer and activator of transcription 6

Stat6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
localization of cell GO:0051674 202 0.642
Fly
regulation of cell proliferation GO:0042127 359 0.622
Mouse Rat Fly
rna metabolic process GO:0016070 406 0.560
cellular response to endogenous stimulus GO:0071495 377 0.471
Rat
response to acid chemical GO:0001101 222 0.445
transcription from rna polymerase ii promoter GO:0006366 252 0.422
macromolecule localization GO:0033036 252 0.392
protein complex assembly GO:0006461 263 0.384
response to external biotic stimulus GO:0043207 221 0.381
Rat Fly
regulation of transcription dna templated GO:0006355 374 0.381
response to estrogen GO:0043627 232 0.373
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.363
cellular component biogenesis GO:0044085 368 0.356
positive regulation of biosynthetic process GO:0009891 319 0.348
positive regulation of cell motility GO:2000147 97 0.338
cellular component assembly GO:0022607 360 0.335
response to corticosteroid GO:0031960 235 0.322
regulation of anatomical structure morphogenesis GO:0022603 141 0.319
Rat
regulation of rna biosynthetic process GO:2001141 381 0.314
aging GO:0007568 241 0.312
Rat
regeneration GO:0031099 163 0.307
intracellular signal transduction GO:0035556 314 0.301
Rat Fly
response to carbohydrate GO:0009743 183 0.297
cellular response to organic cyclic compound GO:0071407 202 0.297
regulation of cell motility GO:2000145 131 0.295
positive regulation of response to stimulus GO:0048584 285 0.288
Mouse
cell projection organization GO:0030030 302 0.284
positive regulation of cell death GO:0010942 184 0.281
transcription dna templated GO:0006351 377 0.280
positive regulation of cell communication GO:0010647 271 0.279
neuron differentiation GO:0030182 368 0.270
response to nutrient levels GO:0031667 370 0.266
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.263
Rat
cell motility GO:0048870 202 0.260
Fly
oxoacid metabolic process GO:0043436 290 0.260
response to other organism GO:0051707 220 0.254
Rat Fly
cellular response to hormone stimulus GO:0032870 247 0.254
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.252
response to peptide hormone GO:0043434 278 0.249
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.246
negative regulation of macromolecule metabolic process GO:0010605 260 0.236
Mouse Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.230
Mouse Rat
response to vitamin d GO:0033280 34 0.230
oxidation reduction process GO:0055114 304 0.229
response to nutrient GO:0007584 248 0.225
Rat
response to extracellular stimulus GO:0009991 380 0.219
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.218
Mouse
regulation of signal transduction GO:0009966 318 0.215
Fly
positive regulation of cellular component movement GO:0051272 102 0.206
Rat
response to bacterium GO:0009617 200 0.202
Rat Fly
negative regulation of cellular metabolic process GO:0031324 281 0.201
Mouse Rat
response to molecule of bacterial origin GO:0002237 194 0.198
Rat Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.196
regulation of nucleic acid templated transcription GO:1903506 380 0.196
positive regulation of cellular component organization GO:0051130 200 0.192
response to peptide GO:1901652 292 0.191
Rat
response to monosaccharide GO:0034284 159 0.190
negative regulation of gene expression GO:0010629 199 0.188
Mouse Rat
regulation of rna metabolic process GO:0051252 391 0.188
establishment of protein localization GO:0045184 141 0.187
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.187
positive regulation of cell migration GO:0030335 96 0.186
positive regulation of transcription dna templated GO:0045893 197 0.184
macromolecular complex subunit organization GO:0043933 339 0.184
negative regulation of developmental process GO:0051093 125 0.180
Rat Fly
response to glucocorticoid GO:0051384 223 0.180
positive regulation of gene expression GO:0010628 244 0.179
neuron projection development GO:0031175 273 0.178
negative regulation of metabolic process GO:0009892 331 0.174
Mouse Rat
response to hydrogen peroxide GO:0042542 89 0.173
regulation of protein metabolic process GO:0051246 289 0.172
regulation of locomotion GO:0040012 148 0.168
positive regulation of rna biosynthetic process GO:1902680 197 0.164
response to cytokine GO:0034097 215 0.163
cellular amino acid metabolic process GO:0006520 107 0.158
regulation of cell development GO:0060284 263 0.158
Rat
response to purine containing compound GO:0014074 126 0.158
Rat
renal system development GO:0072001 67 0.157
Rat
defense response GO:0006952 194 0.156
Rat Fly
cell migration GO:0016477 197 0.155
Fly
regulation of cellular protein metabolic process GO:0032268 267 0.154
protein complex subunit organization GO:0071822 302 0.153
carboxylic acid metabolic process GO:0019752 289 0.152
negative regulation of response to stimulus GO:0048585 155 0.151
Mouse Fly
negative regulation of rna metabolic process GO:0051253 123 0.150
Mouse Rat
organic acid metabolic process GO:0006082 292 0.149
rna biosynthetic process GO:0032774 380 0.149
cellular response to nitrogen compound GO:1901699 210 0.149
regulation of molecular function GO:0065009 398 0.148
protein transport GO:0015031 132 0.148
protein oligomerization GO:0051259 191 0.143
response to glucose GO:0009749 136 0.143
urogenital system development GO:0001655 78 0.142
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.140
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.140
Mouse Rat
nucleic acid templated transcription GO:0097659 379 0.138
positive regulation of cell differentiation GO:0045597 217 0.138
response to wounding GO:0009611 254 0.134
positive regulation of protein phosphorylation GO:0001934 135 0.129
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.129
response to mechanical stimulus GO:0009612 134 0.129
Rat
positive regulation of cell development GO:0010720 176 0.128
response to tumor necrosis factor GO:0034612 56 0.128
neuron development GO:0048666 286 0.128
regulation of cellular component organization GO:0051128 368 0.128
Rat
response to estradiol GO:0032355 164 0.126
Rat
regulation of cell projection organization GO:0031344 175 0.122
wound healing GO:0042060 122 0.122
protein complex biogenesis GO:0070271 263 0.116
response to vitamin GO:0033273 131 0.114
regulation of nervous system development GO:0051960 264 0.113
positive regulation of biomineral tissue development GO:0070169 4 0.113
muscle cell proliferation GO:0033002 84 0.113
Rat
response to interleukin 1 GO:0070555 55 0.112
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.111
Mouse Rat
central nervous system development GO:0007417 311 0.110
response to amino acid GO:0043200 75 0.109
macromolecular complex assembly GO:0065003 273 0.109
regulation of protein localization GO:0032880 81 0.108
cellular response to external stimulus GO:0071496 118 0.108
phospholipid metabolic process GO:0006644 61 0.107
protein localization GO:0008104 191 0.107
regulation of response to stress GO:0080134 126 0.105
Fly
reproductive system development GO:0061458 128 0.105
Rat
cellular response to oxygen containing compound GO:1901701 386 0.104
intracellular transport GO:0046907 185 0.104
Rat
response to hexose GO:0009746 144 0.103
neurological system process GO:0050877 219 0.103
Fly
cellular response to lipid GO:0071396 201 0.103
Fly
positive regulation of molecular function GO:0044093 230 0.102
negative regulation of biosynthetic process GO:0009890 168 0.100
Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.100
regulation of cellular component movement GO:0051270 150 0.099
Rat
anatomical structure morphogenesis GO:0009653 298 0.099
Mouse Rat Fly
regulation of protein phosphorylation GO:0001932 183 0.098
regulation of protein modification process GO:0031399 194 0.098
positive regulation of signaling GO:0023056 270 0.097
regulation of cell morphogenesis GO:0022604 77 0.097
Rat
cellular response to biotic stimulus GO:0071216 59 0.097
Fly
cellular amine metabolic process GO:0044106 38 0.097
response to camp GO:0051591 91 0.096
Rat
regulation of cell migration GO:0030334 128 0.096
cellular response to insulin stimulus GO:0032869 81 0.095
Rat
positive regulation of cell projection organization GO:0031346 111 0.095
positive regulation of protein metabolic process GO:0051247 178 0.095
lipid metabolic process GO:0006629 283 0.095
single organism biosynthetic process GO:0044711 342 0.095
Rat
homeostatic process GO:0042592 331 0.095
negative regulation of cell differentiation GO:0045596 99 0.094
Rat Fly
regulation of cellular component biogenesis GO:0044087 86 0.093
positive regulation of developmental process GO:0051094 283 0.092
Mouse
axon development GO:0061564 96 0.092
protein maturation GO:0051604 68 0.090
anatomical structure formation involved in morphogenesis GO:0048646 83 0.090
Fly
positive regulation of rna metabolic process GO:0051254 203 0.089
single organism reproductive process GO:0044702 297 0.088
Rat Fly
cellular component morphogenesis GO:0032989 155 0.088
Rat Fly
organic substance catabolic process GO:1901575 316 0.087
negative regulation of cell communication GO:0010648 158 0.087
Fly
apoptotic process GO:0006915 381 0.087
cell projection assembly GO:0030031 21 0.086
developmental process involved in reproduction GO:0003006 159 0.085
Rat Fly
regulation of membrane potential GO:0042391 110 0.084
regulation of intracellular signal transduction GO:1902531 218 0.082
Fly
blood vessel development GO:0001568 69 0.082
tissue development GO:0009888 252 0.081
Mouse Rat Fly
positive regulation of neurogenesis GO:0050769 165 0.081
response to reactive oxygen species GO:0000302 120 0.081
regulation of phosphate metabolic process GO:0019220 349 0.081
Rat
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.080
retinoic acid receptor signaling pathway GO:0048384 7 0.080
negative regulation of transcription dna templated GO:0045892 116 0.080
Mouse Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.080
Rat
regulation of neurogenesis GO:0050767 247 0.080
positive regulation of transferase activity GO:0051347 81 0.079
regulation of multicellular organismal development GO:2000026 376 0.079
Mouse Rat
negative regulation of signaling GO:0023057 157 0.078
Fly
cellular response to lipopolysaccharide GO:0071222 55 0.077
Fly
positive regulation of apoptotic process GO:0043065 154 0.076
positive regulation of cellular protein metabolic process GO:0032270 167 0.076
response to lipopolysaccharide GO:0032496 191 0.076
Rat Fly
regulation of cellular amine metabolic process GO:0033238 8 0.076
regulation of neuron differentiation GO:0045664 208 0.075
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.075
regulation of cellular ketone metabolic process GO:0010565 27 0.075
regulation of cell adhesion GO:0030155 52 0.075
negative regulation of cell development GO:0010721 82 0.075
Rat
catabolic process GO:0009056 351 0.074
generation of precursor metabolites and energy GO:0006091 62 0.074
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.074
Mouse Rat
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.074
regulation of neuron death GO:1901214 115 0.073
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.073
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.073
Rat
positive regulation of cell proliferation GO:0008284 249 0.072
Rat Fly
response to oxygen levels GO:0070482 265 0.072
Rat
regulation of catalytic activity GO:0050790 304 0.072
single organism catabolic process GO:0044712 283 0.071
response to inorganic substance GO:0010035 377 0.071
cell morphogenesis involved in differentiation GO:0000904 119 0.070
Rat Fly
cellular nitrogen compound catabolic process GO:0044270 163 0.070
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.070
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.070
Mouse Rat
activation of protein kinase activity GO:0032147 47 0.070
cellular carbohydrate metabolic process GO:0044262 72 0.069
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.069
response to ketone GO:1901654 182 0.068
positive regulation of signal transduction GO:0009967 175 0.068
head development GO:0060322 247 0.068
cellular response to tumor necrosis factor GO:0071356 46 0.067
organophosphate metabolic process GO:0019637 370 0.065
Rat
gliogenesis GO:0042063 93 0.065
regulation of protein secretion GO:0050708 28 0.065
purine containing compound metabolic process GO:0072521 253 0.064
Rat
cell activation GO:0001775 97 0.064
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.064
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 5 0.063
organonitrogen compound catabolic process GO:1901565 179 0.063
positive regulation of protein modification process GO:0031401 142 0.063
secretion GO:0046903 307 0.063
Rat
regulation of establishment of protein localization GO:0070201 69 0.062
protein phosphorylation GO:0006468 345 0.062
response to aluminum ion GO:0010044 10 0.061
cell adhesion GO:0007155 110 0.061
leukocyte activation GO:0045321 76 0.061
Mouse
purine ribonucleotide metabolic process GO:0009150 227 0.061
Rat
response to axon injury GO:0048678 59 0.061
regulation of apoptotic process GO:0042981 335 0.061
regulation of kinase activity GO:0043549 117 0.061
negative regulation of protein import into nucleus translocation GO:0033159 1 0.060
cellular response to steroid hormone stimulus GO:0071383 93 0.060
neuronal action potential GO:0019228 35 0.060
negative regulation of cellular biosynthetic process GO:0031327 161 0.060
Mouse Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.059
Rat
organ regeneration GO:0031100 101 0.059
calcium ion transport GO:0006816 131 0.059
mesenchymal cell proliferation GO:0010463 4 0.058
Rat
response to hypoxia GO:0001666 231 0.057
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.057
Rat
response to temperature stimulus GO:0009266 94 0.057
regulation of system process GO:0044057 208 0.057
single organism membrane organization GO:0044802 74 0.056
Rat
positive regulation of i kappab kinase nf kappab signaling GO:0043123 8 0.055
protein autophosphorylation GO:0046777 66 0.055
negative regulation of cellular protein metabolic process GO:0032269 106 0.055
purine nucleoside triphosphate catabolic process GO:0009146 122 0.054
regulation of lipid metabolic process GO:0019216 68 0.054
gland development GO:0048732 155 0.054
Mouse Rat Fly
positive regulation of mitochondrion organization GO:0010822 4 0.054
lymphocyte activation GO:0046649 43 0.054
Mouse
regulation of programmed cell death GO:0043067 341 0.054
ribonucleotide metabolic process GO:0009259 231 0.053
Rat
microvillus assembly GO:0030033 2 0.053
immune response GO:0006955 104 0.053
Mouse Fly
reproduction GO:0000003 245 0.053
Rat Fly
regulation of transferase activity GO:0051338 123 0.052
regulation of protein import into nucleus GO:0042306 24 0.052
response to mineralocorticoid GO:0051385 49 0.051
regulation of protein transport GO:0051223 68 0.051
biological adhesion GO:0022610 110 0.051
purine nucleotide metabolic process GO:0006163 229 0.050
Rat
salivary gland development GO:0007431 3 0.050
single organism intracellular transport GO:1902582 166 0.050
Rat
regulation of endocytosis GO:0030100 42 0.050
regulation of phosphorylation GO:0042325 248 0.050
cellular component movement GO:0006928 248 0.050
Rat Fly
intracellular protein transport GO:0006886 79 0.050
positive regulation of neuron projection development GO:0010976 99 0.049
positive regulation of nervous system development GO:0051962 178 0.049
macrophage chemotaxis GO:0048246 2 0.049
carbohydrate derivative metabolic process GO:1901135 346 0.049
Rat
female gonad development GO:0008585 53 0.049
Rat
response to insulin GO:0032868 133 0.049
Rat
negative regulation of cell death GO:0060548 229 0.049
Rat
cellular response to acid chemical GO:0071229 75 0.048
negative regulation of nervous system development GO:0051961 79 0.048
negative regulation of rna biosynthetic process GO:1902679 118 0.048
Mouse Rat
metal ion homeostasis GO:0055065 186 0.048
cellular response to organonitrogen compound GO:0071417 197 0.048
Rat
intracellular receptor signaling pathway GO:0030522 35 0.048
negative regulation of phosphorus metabolic process GO:0010563 80 0.048
negative regulation of cell proliferation GO:0008285 119 0.047
positive regulation of endothelial cell migration GO:0010595 4 0.047
reactive oxygen species metabolic process GO:0072593 37 0.047
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.047
cell morphogenesis GO:0000902 142 0.047
Rat Fly
response to biotic stimulus GO:0009607 226 0.047
Rat Fly
brain development GO:0007420 247 0.046
positive regulation of programmed cell death GO:0043068 157 0.046
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.046
Rat
protein targeting GO:0006605 61 0.046
nucleoside triphosphate metabolic process GO:0009141 144 0.045
Rat
ensheathment of neurons GO:0007272 40 0.045
liver development GO:0001889 90 0.045
Rat
response to retinoic acid GO:0032526 63 0.045
regulation of defense response GO:0031347 68 0.044
Fly
reproductive process GO:0022414 372 0.044
Rat Fly
regulation of cellular localization GO:0060341 263 0.044
regulation of translation GO:0006417 27 0.044
jak stat cascade GO:0007259 26 0.044
Rat Fly
behavior GO:0007610 205 0.044
Fly
regulation of protein kinase activity GO:0045859 105 0.043
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.043
memory GO:0007613 54 0.043
Fly
cell cell junction organization GO:0045216 20 0.042
locomotion GO:0040011 237 0.042
Fly
positive regulation of response to external stimulus GO:0032103 51 0.042
circulatory system development GO:0072359 134 0.042
positive regulation of cell adhesion GO:0045785 30 0.042
transmembrane transport GO:0055085 412 0.042
insulin receptor signaling pathway GO:0008286 24 0.042
programmed cell death GO:0012501 392 0.042
t cell homeostasis GO:0043029 2 0.042
protein homooligomerization GO:0051260 91 0.041
positive regulation of protein kinase activity GO:0045860 73 0.041
organic cyclic compound catabolic process GO:1901361 175 0.041
positive regulation of lipid kinase activity GO:0090218 2 0.041
reactive oxygen species biosynthetic process GO:1903409 8 0.041
Rat
cellular response to mechanical stimulus GO:0071260 48 0.041
negative regulation of protein phosphorylation GO:0001933 44 0.041
cellular homeostasis GO:0019725 252 0.041
membrane organization GO:0061024 94 0.041
Rat
cytoplasmic transport GO:0016482 115 0.040
regulation of cell differentiation GO:0045595 320 0.040
Rat Fly
regulation of protein targeting GO:1903533 28 0.040
peptidyl amino acid modification GO:0018193 126 0.040
activation of protein kinase b activity GO:0032148 3 0.040
cell projection morphogenesis GO:0048858 123 0.040
positive regulation of release of cytochrome c from mitochondria GO:0090200 3 0.039
cell junction organization GO:0034330 21 0.039
cellular protein localization GO:0034613 122 0.039
ribonucleoside triphosphate metabolic process GO:0009199 141 0.039
Rat
cellular response to molecule of bacterial origin GO:0071219 56 0.039
Fly
negative regulation of neuron apoptotic process GO:0043524 45 0.039
purine nucleoside metabolic process GO:0042278 169 0.039
Rat
regulation of smooth muscle cell proliferation GO:0048660 75 0.038
Rat
cellular response to peptide GO:1901653 133 0.038
Rat
alpha beta t cell differentiation GO:0046632 2 0.038
Mouse
gamete generation GO:0007276 124 0.038
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.038
cellular response to cytokine stimulus GO:0071345 127 0.037
appendage morphogenesis GO:0035107 4 0.037
blood circulation GO:0008015 183 0.037
Rat
cellular macromolecule localization GO:0070727 122 0.037
response to growth factor GO:0070848 189 0.036
Rat
regulation of response to external stimulus GO:0032101 106 0.036
Fly
positive regulation of kinase activity GO:0033674 77 0.036
vasculogenesis GO:0001570 3 0.036
axon ensheathment GO:0008366 40 0.036
protein heterooligomerization GO:0051291 89 0.036
purine containing compound catabolic process GO:0072523 138 0.036
organ formation GO:0048645 3 0.036
embryonic neurocranium morphogenesis GO:0048702 2 0.036
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.036
glial cell apoptotic process GO:0034349 8 0.035
ribonucleotide catabolic process GO:0009261 136 0.035
regulation of anatomical structure size GO:0090066 135 0.035
ameboidal type cell migration GO:0001667 26 0.035
Fly
cellular chemical homeostasis GO:0055082 247 0.035
dna metabolic process GO:0006259 96 0.035
Mouse
glycosyl compound metabolic process GO:1901657 182 0.035
Rat
vesicle mediated transport GO:0016192 181 0.034
secretion by cell GO:0032940 248 0.034
positive regulation of neuron differentiation GO:0045666 126 0.034
nucleoside phosphate metabolic process GO:0006753 283 0.034
Rat
positive regulation of bone mineralization GO:0030501 4 0.034
organelle organization GO:0006996 266 0.034
Rat
actin filament bundle organization GO:0061572 19 0.034
smooth muscle cell proliferation GO:0048659 77 0.034
Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.034
b cell differentiation GO:0030183 2 0.034
single organism behavior GO:0044708 130 0.034
Fly
cytokine production GO:0001816 61 0.033
positive regulation of protein secretion GO:0050714 19 0.033
regulation of response to wounding GO:1903034 69 0.033
regulation of vesicle mediated transport GO:0060627 81 0.033
smad protein complex assembly GO:0007183 1 0.033
regulation of neuron projection development GO:0010975 161 0.033
cellular catabolic process GO:0044248 295 0.033
glial cell differentiation GO:0010001 65 0.032
female pregnancy GO:0007565 122 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
Rat
spindle organization GO:0007051 2 0.032
nucleobase containing compound catabolic process GO:0034655 152 0.032
negative regulation of phosphate metabolic process GO:0045936 80 0.032
maintenance of location GO:0051235 17 0.032
negative regulation of signal transduction GO:0009968 83 0.032
Fly
multicellular organismal reproductive process GO:0048609 233 0.031
Rat Fly
cardiovascular system development GO:0072358 134 0.031
glycosyl compound catabolic process GO:1901658 126 0.031
positive regulation of smooth muscle cell migration GO:0014911 27 0.031
organ morphogenesis GO:0009887 75 0.031
Mouse Rat Fly
purine nucleoside triphosphate metabolic process GO:0009144 141 0.031
Rat
translation GO:0006412 35 0.031
neuron projection regeneration GO:0031102 35 0.031
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.031
tissue regeneration GO:0042246 36 0.031
negative regulation of protein metabolic process GO:0051248 114 0.031
formation of primary germ layer GO:0001704 1 0.031
fatty acid transmembrane transport GO:1902001 3 0.031
response to transition metal nanoparticle GO:1990267 122 0.030
embryonic cranial skeleton morphogenesis GO:0048701 2 0.030
rhythmic process GO:0048511 156 0.030
Rat
peptidyl tyrosine modification GO:0018212 72 0.030
vascular process in circulatory system GO:0003018 96 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.030
Rat
myelination GO:0042552 39 0.030
camera type eye development GO:0043010 48 0.030
sulfur compound metabolic process GO:0006790 70 0.030
regulation of immune system process GO:0002682 123 0.030
Mouse Fly
kidney development GO:0001822 67 0.030
Rat
protein import GO:0017038 37 0.030
chemotaxis GO:0006935 66 0.030
regulation of ion transport GO:0043269 245 0.029
negative regulation of transport GO:0051051 136 0.029
divalent inorganic cation transport GO:0072511 134 0.029
regulation of map kinase activity GO:0043405 53 0.029
protein localization to nucleus GO:0034504 39 0.029
polysaccharide metabolic process GO:0005976 25 0.029
negative regulation of programmed cell death GO:0043069 183 0.029
protein import into nucleus GO:0006606 35 0.029
positive regulation of locomotion GO:0040017 102 0.029
calcium ion homeostasis GO:0055074 162 0.028
bmp signaling pathway GO:0030509 4 0.028
synaptic growth at neuromuscular junction GO:0051124 1 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
cation transport GO:0006812 382 0.028
protein targeting to nucleus GO:0044744 35 0.028
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.028
sodium ion transport GO:0006814 82 0.028
response to transforming growth factor beta GO:0071559 46 0.027
reproductive structure development GO:0048608 128 0.027
Rat
positive regulation of immune system process GO:0002684 90 0.027
Mouse
cellular lipid metabolic process GO:0044255 208 0.027
neuron apoptotic process GO:0051402 88 0.027
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.027
Rat
monovalent inorganic cation transport GO:0015672 172 0.027
chemical homeostasis GO:0048878 292 0.027
nucleoside metabolic process GO:0009116 179 0.027
Rat
regulation of muscle organ development GO:0048634 26 0.026
positive regulation of secretion by cell GO:1903532 128 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
positive regulation of immunoglobulin production GO:0002639 4 0.026
Mouse
positive regulation of hydrolase activity GO:0051345 86 0.026
nucleoside phosphate catabolic process GO:1901292 140 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
cellular response to stress GO:0033554 269 0.026
learning or memory GO:0007611 90 0.026
Fly
negative regulation of cellular component organization GO:0051129 83 0.026
Rat
nuclear import GO:0051170 35 0.026
t cell tolerance induction GO:0002517 3 0.026
positive regulation of protein transport GO:0051222 41 0.026
cellular response to nutrient levels GO:0031669 60 0.026
positive regulation of transport GO:0051050 245 0.026
response to alkaloid GO:0043279 132 0.026
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.026
peptidyl tyrosine phosphorylation GO:0018108 72 0.026
organ growth GO:0035265 24 0.026
eye morphogenesis GO:0048592 4 0.025
response to organophosphorus GO:0046683 102 0.025
Rat
regulation of reactive oxygen species metabolic process GO:2000377 26 0.025
Rat
negative regulation of molecular function GO:0044092 133 0.025
positive regulation of map kinase activity GO:0043406 46 0.025
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.025
regulation of carbohydrate metabolic process GO:0006109 41 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.025
Mouse Rat
protein localization to organelle GO:0033365 57 0.025
regulation of blood vessel size GO:0050880 89 0.025
myeloid leukocyte differentiation GO:0002573 20 0.025
positive regulation of cellular catabolic process GO:0031331 71 0.025
negative regulation of intracellular signal transduction GO:1902532 38 0.025
single organism organelle organization GO:1902589 180 0.025
Rat
transmission of nerve impulse GO:0019226 42 0.025
gonad development GO:0008406 104 0.025
Rat
negative regulation of neuron differentiation GO:0045665 62 0.024
organophosphate catabolic process GO:0046434 148 0.024
mesoderm development GO:0007498 2 0.024
response to oxidative stress GO:0006979 186 0.024
positive regulation of cellular component biogenesis GO:0044089 55 0.024
nucleotide metabolic process GO:0009117 279 0.024
Rat
cellular response to extracellular stimulus GO:0031668 73 0.024
organonitrogen compound biosynthetic process GO:1901566 167 0.024
Rat
regulation of organ formation GO:0003156 2 0.024
male sex differentiation GO:0046661 64 0.024
regulation of hydrolase activity GO:0051336 143 0.024
dephosphorylation GO:0016311 98 0.024
nitrogen compound transport GO:0071705 229 0.024
telencephalon development GO:0021537 62 0.024
t cell activation GO:0042110 29 0.024
Mouse
cytoskeleton organization GO:0007010 111 0.024
cellular glucan metabolic process GO:0006073 23 0.023

Stat6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
large intestine cancer DOID:5672 0 0.024
colon cancer DOID:219 0 0.024
gastrointestinal system cancer DOID:3119 0 0.024
intestinal cancer DOID:10155 0 0.024
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024
colorectal cancer DOID:9256 0 0.024