Rattus norvegicus

197 known processes

Stat3

signal transducer and activator of transcription 3

(Aliases: MGC93551)

Stat3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 204 0.646
positive regulation of multicellular organismal process GO:0051240 387 0.511
Zebrafish
transcription dna templated GO:0006351 377 0.500
Human Mouse Rat
response to interleukin 1 GO:0070555 55 0.421
positive regulation of response to stimulus GO:0048584 285 0.396
Mouse
inflammatory response GO:0006954 150 0.379
programmed cell death GO:0012501 392 0.368
apoptotic process GO:0006915 381 0.368
intracellular signal transduction GO:0035556 314 0.363
Human Zebrafish Mouse Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.347
response to molecule of bacterial origin GO:0002237 194 0.340
Rat
negative regulation of metabolic process GO:0009892 331 0.324
cellular response to cytokine stimulus GO:0071345 127 0.307
Human Rat
positive regulation of signal transduction GO:0009967 175 0.304
Mouse
transcription from rna polymerase ii promoter GO:0006366 252 0.303
Human Mouse Rat
reproductive system development GO:0061458 128 0.301
Rat
regulation of apoptotic process GO:0042981 335 0.285
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.282
regulation of rna biosynthetic process GO:2001141 381 0.273
Human Mouse Rat
negative regulation of gene expression GO:0010629 199 0.262
Rat
regulation of protein metabolic process GO:0051246 289 0.259
aging GO:0007568 241 0.258
regulation of programmed cell death GO:0043067 341 0.250
cellular response to hormone stimulus GO:0032870 247 0.241
Human Mouse Rat
organic acid metabolic process GO:0006082 292 0.233
Mouse
negative regulation of apoptotic process GO:0043066 181 0.228
defense response GO:0006952 194 0.228
cytokine mediated signaling pathway GO:0019221 43 0.222
Human Rat
response to decreased oxygen levels GO:0036293 237 0.211
Rat
tumor necrosis factor superfamily cytokine production GO:0071706 13 0.207
cellular response to oxygen containing compound GO:1901701 386 0.199
Human Mouse Rat
response to cytokine GO:0034097 215 0.196
cell projection organization GO:0030030 302 0.194
Zebrafish
positive regulation of tyrosine phosphorylation of stat1 protein GO:0042511 1 0.194
response to peptide hormone GO:0043434 278 0.193
cellular response to lipopolysaccharide GO:0071222 55 0.186
cellular response to tumor necrosis factor GO:0071356 46 0.185
protein oligomerization GO:0051259 191 0.180
immune response GO:0006955 104 0.179
cytokine production GO:0001816 61 0.175
rna biosynthetic process GO:0032774 380 0.172
Human Mouse Rat
regulation of cellular protein metabolic process GO:0032268 267 0.171
circulatory system development GO:0072359 134 0.163
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.156
positive regulation of signaling GO:0023056 270 0.152
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.152
response to nutrient GO:0007584 248 0.152
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.152
regulation of cellular amine metabolic process GO:0033238 8 0.146
regulation of rna metabolic process GO:0051252 391 0.146
Human Mouse Rat
cellular homeostasis GO:0019725 252 0.146
rna metabolic process GO:0016070 406 0.145
Human Mouse Rat
carboxylic acid metabolic process GO:0019752 289 0.144
Mouse
cellular response to stress GO:0033554 269 0.143
Rat
tumor necrosis factor production GO:0032640 13 0.140
negative regulation of programmed cell death GO:0043069 183 0.138
response to transition metal nanoparticle GO:1990267 122 0.137
response to tumor necrosis factor GO:0034612 56 0.136
positive regulation of immune system process GO:0002684 90 0.135
regulation of cell proliferation GO:0042127 359 0.135
response to metal ion GO:0010038 253 0.134
regulation of molecular function GO:0065009 398 0.134
nucleic acid templated transcription GO:0097659 379 0.128
Human Mouse Rat
response to inorganic substance GO:0010035 377 0.126
Rat
positive regulation of biosynthetic process GO:0009891 319 0.126
negative regulation of cell death GO:0060548 229 0.126
positive regulation of cell communication GO:0010647 271 0.125
Mouse
cellular amino acid metabolic process GO:0006520 107 0.125
amine metabolic process GO:0009308 38 0.124
positive regulation of rna biosynthetic process GO:1902680 197 0.123
Human Mouse Rat
regulation of response to external stimulus GO:0032101 106 0.122
cellular catabolic process GO:0044248 295 0.120
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.119
positive regulation of i kappab kinase nf kappab signaling GO:0043123 8 0.119
cellular ketone metabolic process GO:0042180 51 0.117
anatomical structure morphogenesis GO:0009653 298 0.117
Zebrafish Mouse Rat
response to extracellular stimulus GO:0009991 380 0.116
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.116
Human Mouse Rat
cellular component assembly GO:0022607 360 0.115
response to oxygen levels GO:0070482 265 0.114
Rat
response to wounding GO:0009611 254 0.112
Zebrafish
response to peptide GO:1901652 292 0.108
macromolecule localization GO:0033036 252 0.108
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.108
Rat
peptidyl tyrosine phosphorylation GO:0018108 72 0.107
protein localization GO:0008104 191 0.107
Human
response to fluoride GO:1902617 3 0.107
cellular response to molecule of bacterial origin GO:0071219 56 0.107
protein complex subunit organization GO:0071822 302 0.106
protein phosphorylation GO:0006468 345 0.105
cellular response to nitrogen compound GO:1901699 210 0.105
Human Mouse Rat
regulation of cytokine production GO:0001817 56 0.105
regulation of intracellular signal transduction GO:1902531 218 0.103
macromolecular complex subunit organization GO:0043933 339 0.103
regulation of immune system process GO:0002682 123 0.102
regulation of multicellular organismal development GO:2000026 376 0.101
Zebrafish Mouse Rat
chemical homeostasis GO:0048878 292 0.097
Mouse
regulation of cellular component movement GO:0051270 150 0.097
Mouse Rat
tissue development GO:0009888 252 0.096
Zebrafish Rat
peptidyl amino acid modification GO:0018193 126 0.095
positive regulation of cell differentiation GO:0045597 217 0.094
Zebrafish
head development GO:0060322 247 0.094
cellular response to interleukin 1 GO:0071347 37 0.093
positive regulation of tumor necrosis factor production GO:0032760 8 0.092
regulation of cellular localization GO:0060341 263 0.091
homeostatic process GO:0042592 331 0.091
Mouse
catabolic process GO:0009056 351 0.090
Mouse
positive regulation of neurogenesis GO:0050769 165 0.090
Zebrafish
neuron projection development GO:0031175 273 0.090
Zebrafish
female sex differentiation GO:0046660 59 0.089
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.089
response to other organism GO:0051707 220 0.088
Rat
cation transport GO:0006812 382 0.087
regulation of smooth muscle cell proliferation GO:0048660 75 0.087
Rat
response to hypoxia GO:0001666 231 0.086
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.085
regulation of response to wounding GO:1903034 69 0.085
gonad development GO:0008406 104 0.084
Rat
protein complex assembly GO:0006461 263 0.084
cellular chemical homeostasis GO:0055082 247 0.084
cellular response to organonitrogen compound GO:0071417 197 0.082
Human Mouse Rat
regulation of catalytic activity GO:0050790 304 0.080
response to lipopolysaccharide GO:0032496 191 0.080
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.079
innate immune response GO:0045087 35 0.079
regulation of transcription dna templated GO:0006355 374 0.079
Human Mouse Rat
cell type specific apoptotic process GO:0097285 134 0.078
peptidyl tyrosine modification GO:0018212 72 0.077
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.076
Human Mouse
cellular response to endogenous stimulus GO:0071495 377 0.076
Human Mouse Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.075
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.075
Human Mouse Rat
negative regulation of cytokine production GO:0001818 16 0.075
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.075
Rat
reproductive process GO:0022414 372 0.074
Mouse Rat
multicellular organism reproduction GO:0032504 233 0.074
Rat
organic anion transport GO:0015711 132 0.074
central nervous system development GO:0007417 311 0.073
Mouse
positive regulation of humoral immune response GO:0002922 2 0.073
multi organism reproductive process GO:0044703 262 0.072
Mouse
development of primary female sexual characteristics GO:0046545 56 0.072
Rat
tetrapyrrole metabolic process GO:0033013 11 0.071
negative regulation of muscle cell apoptotic process GO:0010656 21 0.071
proteolysis GO:0006508 175 0.071
regulation of phosphorus metabolic process GO:0051174 349 0.071
regulation of signal transduction GO:0009966 318 0.070
Mouse
cellular response to biotic stimulus GO:0071216 59 0.069
ovulation cycle process GO:0022602 50 0.068
Rat
carbohydrate homeostasis GO:0033500 75 0.067
Mouse
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.067
positive regulation of defense response GO:0031349 37 0.067
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 13 0.066
cellular amine metabolic process GO:0044106 38 0.066
reactive oxygen species biosynthetic process GO:1903409 8 0.066
female gonad development GO:0008585 53 0.066
Rat
calcium ion transport GO:0006816 131 0.065
signal transduction by phosphorylation GO:0023014 144 0.064
liver development GO:0001889 90 0.064
Rat
secretion GO:0046903 307 0.064
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.063
intracellular transport GO:0046907 185 0.062
regulation of protein phosphorylation GO:0001932 183 0.062
organonitrogen compound biosynthetic process GO:1901566 167 0.062
positive regulation of developmental process GO:0051094 283 0.061
Zebrafish
macromolecular complex assembly GO:0065003 273 0.060
activation of immune response GO:0002253 26 0.060
nucleotide metabolic process GO:0009117 279 0.060
positive regulation of intracellular signal transduction GO:1902533 138 0.060
multicellular organismal reproductive process GO:0048609 233 0.060
Rat
reactive oxygen species metabolic process GO:0072593 37 0.060
regulation of canonical wnt signaling pathway GO:0060828 4 0.060
cardiovascular system development GO:0072358 134 0.059
cellular response to lipid GO:0071396 201 0.058
hepaticobiliary system development GO:0061008 90 0.058
Rat
sex differentiation GO:0007548 113 0.058
Rat
negative regulation of rna metabolic process GO:0051253 123 0.056
Rat
insulin receptor signaling pathway GO:0008286 24 0.056
urogenital system development GO:0001655 78 0.055
Rat
cellular metal ion homeostasis GO:0006875 172 0.055
regulation of protein localization GO:0032880 81 0.055
nucleobase containing small molecule metabolic process GO:0055086 316 0.054
positive regulation of phosphate metabolic process GO:0045937 262 0.053
regulation of hormone levels GO:0010817 187 0.053
single organism reproductive process GO:0044702 297 0.053
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.053
cytokine biosynthetic process GO:0042089 3 0.052
carbohydrate derivative biosynthetic process GO:1901137 124 0.052
response to external biotic stimulus GO:0043207 221 0.052
Rat
positive regulation of molecular function GO:0044093 230 0.051
enzyme linked receptor protein signaling pathway GO:0007167 116 0.051
Human Mouse
growth GO:0040007 165 0.051
Zebrafish Mouse
carbohydrate derivative metabolic process GO:1901135 346 0.050
single organism intracellular transport GO:1902582 166 0.050
jak stat cascade GO:0007259 26 0.050
Human Zebrafish Mouse Rat
secretion by cell GO:0032940 248 0.049
neuron differentiation GO:0030182 368 0.048
Zebrafish Mouse
lipid localization GO:0010876 62 0.048
cellular response to external stimulus GO:0071496 118 0.048
cellular component biogenesis GO:0044085 368 0.048
positive regulation of gene expression GO:0010628 244 0.048
Human Mouse Rat
brain development GO:0007420 247 0.047
positive regulation of phosphorylation GO:0042327 177 0.047
inflammatory response to antigenic stimulus GO:0002437 18 0.047
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.047
regulation of inflammatory response GO:0050727 48 0.046
positive regulation of programmed cell death GO:0043068 157 0.046
regulation of secretion by cell GO:1903530 208 0.046
response to bacterium GO:0009617 200 0.046
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.046
Rat
dendrite development GO:0016358 72 0.045
positive regulation of stress activated protein kinase signaling cascade GO:0070304 17 0.045
protein complex biogenesis GO:0070271 263 0.045
response to hexose GO:0009746 144 0.044
calcium ion homeostasis GO:0055074 162 0.044
response to oxidative stress GO:0006979 186 0.044
Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.044
Rat
regulation of defense response GO:0031347 68 0.043
cellular response to peptide hormone stimulus GO:0071375 120 0.043
Human Mouse Rat
cellular response to organic cyclic compound GO:0071407 202 0.043
metal ion transport GO:0030001 289 0.043
response to alkaloid GO:0043279 132 0.042
cellular divalent inorganic cation homeostasis GO:0072503 162 0.042
ribose phosphate metabolic process GO:0019693 235 0.042
positive regulation of transport GO:0051050 245 0.042
response to biotic stimulus GO:0009607 226 0.042
Rat
positive regulation of protein modification process GO:0031401 142 0.042
purine nucleotide metabolic process GO:0006163 229 0.042
cation transmembrane transport GO:0098655 263 0.041
negative regulation of molecular function GO:0044092 133 0.041
metal ion homeostasis GO:0055065 186 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
regulation of interleukin 6 production GO:0032675 12 0.041
immunoglobulin mediated immune response GO:0016064 4 0.041
protein transport GO:0015031 132 0.041
Human
negative regulation of protein metabolic process GO:0051248 114 0.041
cytosolic calcium ion homeostasis GO:0051480 140 0.040
negative regulation of catalytic activity GO:0043086 103 0.040
circulatory system process GO:0003013 183 0.040
Rat
positive regulation of protein transport GO:0051222 41 0.040
negative regulation of multicellular organismal process GO:0051241 203 0.039
Mouse Rat
response to cobalt ion GO:0032025 12 0.039
cation homeostasis GO:0055080 195 0.039
sexual reproduction GO:0019953 148 0.039
Mouse
response to estrogen GO:0043627 232 0.038
response to insulin GO:0032868 133 0.038
Rat
smooth muscle cell proliferation GO:0048659 77 0.038
Rat
regulation of tumor necrosis factor production GO:0032680 13 0.038
positive regulation of cellular component organization GO:0051130 200 0.038
developmental process involved in reproduction GO:0003006 159 0.038
Rat
cell morphogenesis GO:0000902 142 0.038
Zebrafish Rat
oxoacid metabolic process GO:0043436 290 0.038
Mouse
regulation of secretion GO:0051046 224 0.038
regulation of cell differentiation GO:0045595 320 0.037
Zebrafish Mouse Rat
positive regulation of apoptotic process GO:0043065 154 0.037
development of primary sexual characteristics GO:0045137 107 0.037
Rat
reproductive structure development GO:0048608 128 0.037
Rat
positive regulation of cellular component movement GO:0051272 102 0.037
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.037
Rat
regulation of protein modification process GO:0031399 194 0.037
regulation of response to stress GO:0080134 126 0.036
vitamin d biosynthetic process GO:0042368 2 0.036
ovulation cycle GO:0042698 67 0.036
Rat
positive regulation of rna metabolic process GO:0051254 203 0.036
Human Mouse Rat
lipid transport GO:0006869 61 0.036
regulation of protein transport GO:0051223 68 0.036
negative regulation of response to stimulus GO:0048585 155 0.036
cellular calcium ion homeostasis GO:0006874 160 0.036
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.036
Rat
rhythmic process GO:0048511 156 0.035
Rat
apoptotic signaling pathway GO:0097190 27 0.035
response to carbohydrate GO:0009743 183 0.035
digestive system development GO:0055123 41 0.035
Zebrafish
purine ribonucleotide metabolic process GO:0009150 227 0.034
cellular response to insulin stimulus GO:0032869 81 0.034
Rat
cellular response to peptide GO:1901653 133 0.034
Human Mouse Rat
negative regulation of cell communication GO:0010648 158 0.034
negative regulation of rna biosynthetic process GO:1902679 118 0.034
Rat
regulation of phosphorylation GO:0042325 248 0.034
response to nutrient levels GO:0031667 370 0.034
Rat
response to growth factor GO:0070848 189 0.034
Rat
regulation of locomotion GO:0040012 148 0.033
Mouse
response to radiation GO:0009314 137 0.033
transmembrane transport GO:0055085 412 0.033
negative regulation of transcription dna templated GO:0045892 116 0.033
Rat
organic cyclic compound catabolic process GO:1901361 175 0.033
mapk cascade GO:0000165 140 0.033
regulation of purine nucleotide metabolic process GO:1900542 115 0.033
organ regeneration GO:0031100 101 0.033
amide biosynthetic process GO:0043604 10 0.032
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.032
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.032
nucleocytoplasmic transport GO:0006913 48 0.032
Human
regulation of reactive oxygen species metabolic process GO:2000377 26 0.032
single organism cellular localization GO:1902580 102 0.032
Human
regulation of jak stat cascade GO:0046425 21 0.032
heart development GO:0007507 72 0.032
nitrogen compound transport GO:0071705 229 0.032
response to toxic substance GO:0009636 133 0.032
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.032
negative regulation of signaling GO:0023057 157 0.032
small molecule biosynthetic process GO:0044283 124 0.031
organophosphate metabolic process GO:0019637 370 0.031
ribonucleotide metabolic process GO:0009259 231 0.031
negative regulation of phosphorus metabolic process GO:0010563 80 0.031
positive regulation of transcription dna templated GO:0045893 197 0.031
Human Mouse Rat
glucose homeostasis GO:0042593 75 0.030
Mouse
positive regulation of mapk cascade GO:0043410 92 0.030
divalent metal ion transport GO:0070838 132 0.030
leukocyte activation GO:0045321 76 0.030
single organism behavior GO:0044708 130 0.030
regulation of cellular component organization GO:0051128 368 0.029
Rat
positive regulation of neuron projection development GO:0010976 99 0.029
multi multicellular organism process GO:0044706 138 0.029
embryo development GO:0009790 49 0.029
Zebrafish
regulation of nervous system development GO:0051960 264 0.029
Zebrafish Mouse
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.029
regulation of jnk cascade GO:0046328 19 0.029
localization of cell GO:0051674 202 0.029
Zebrafish Mouse
positive regulation of protein metabolic process GO:0051247 178 0.028
positive regulation of cell death GO:0010942 184 0.028
positive regulation of cell development GO:0010720 176 0.028
Zebrafish
immune effector process GO:0002252 53 0.028
leukocyte activation involved in immune response GO:0002366 16 0.028
protein processing GO:0016485 68 0.028
positive regulation of nervous system development GO:0051962 178 0.028
Zebrafish
skeletal system development GO:0001501 41 0.028
oxidation reduction process GO:0055114 304 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
Human Mouse Rat
cellular response to hexose stimulus GO:0071331 65 0.028
neuron development GO:0048666 286 0.028
Zebrafish
establishment of protein localization GO:0045184 141 0.028
Human
interleukin 12 production GO:0032615 3 0.028
response to fungus GO:0009620 8 0.028
cellular ion homeostasis GO:0006873 184 0.027
mirna metabolic process GO:0010586 1 0.027
positive regulation of jak stat cascade GO:0046427 19 0.027
mrna stabilization GO:0048255 2 0.027
response to glucose GO:0009749 136 0.027
hormone metabolic process GO:0042445 69 0.027
purine containing compound metabolic process GO:0072521 253 0.027
positive regulation of neuron apoptotic process GO:0043525 33 0.027
positive regulation of cytokine production GO:0001819 42 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
ion homeostasis GO:0050801 212 0.027
Mouse
response to ammonium ion GO:0060359 71 0.026
response to corticosteroid GO:0031960 235 0.026
purine containing compound biosynthetic process GO:0072522 85 0.026
regulation of apoptotic signaling pathway GO:2001233 13 0.026
muscle system process GO:0003012 115 0.026
cellular nitrogen compound catabolic process GO:0044270 163 0.026
protein heterooligomerization GO:0051291 89 0.026
carbohydrate metabolic process GO:0005975 130 0.026
Mouse
myeloid leukocyte differentiation GO:0002573 20 0.026
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.026
Rat
epithelium development GO:0060429 96 0.025
Zebrafish Rat
regulation of i kappab kinase nf kappab signaling GO:0043122 13 0.025
regulation of hydrolase activity GO:0051336 143 0.025
cytoplasmic transport GO:0016482 115 0.025
Human
negative regulation of response to external stimulus GO:0032102 37 0.025
ribonucleotide biosynthetic process GO:0009260 85 0.025
reproduction GO:0000003 245 0.024
Mouse Rat
regulation of cytokine biosynthetic process GO:0042035 3 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.024
kidney development GO:0001822 67 0.024
Rat
regulation of cell projection organization GO:0031344 175 0.024
leukocyte cell cell adhesion GO:0007159 4 0.024
regulation of metal ion transport GO:0010959 118 0.024
regulation of neuron differentiation GO:0045664 208 0.024
response to amino acid GO:0043200 75 0.024
cellular response to mechanical stimulus GO:0071260 48 0.023
blood vessel development GO:0001568 69 0.023
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.023
cyclic nucleotide metabolic process GO:0009187 80 0.023
positive regulation of response to external stimulus GO:0032103 51 0.023
regulation of cell development GO:0060284 263 0.023
Zebrafish Mouse Rat
divalent inorganic cation transport GO:0072511 134 0.023
positive regulation of nucleotide metabolic process GO:0045981 91 0.023
organelle organization GO:0006996 266 0.023
negative regulation of transport GO:0051051 136 0.023
positive regulation of secretion by cell GO:1903532 128 0.022
response to peptidoglycan GO:0032494 1 0.022
cell part morphogenesis GO:0032990 123 0.022
Zebrafish
female pregnancy GO:0007565 122 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
positive regulation of angiogenesis GO:0045766 28 0.022
axis specification GO:0009798 4 0.022
regulation of nucleotide metabolic process GO:0006140 117 0.022
defense response to other organism GO:0098542 17 0.022
tube development GO:0035295 89 0.022
Zebrafish Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.022
organ morphogenesis GO:0009887 75 0.022
Zebrafish Mouse Rat
cell adhesion GO:0007155 110 0.022
regulation of transforming growth factor beta3 production GO:0032910 2 0.022
positive regulation of immunoglobulin production GO:0002639 4 0.021
regulation of vesicle mediated transport GO:0060627 81 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
response to monosaccharide GO:0034284 159 0.021
response to acid chemical GO:0001101 222 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.020
regulation of stem cell proliferation GO:0072091 14 0.020
Rat
eye development GO:0001654 50 0.020
Zebrafish Mouse
response to glucocorticoid GO:0051384 223 0.020
regulation of mapk cascade GO:0043408 116 0.020
signal release GO:0023061 145 0.020
cellular component morphogenesis GO:0032989 155 0.020
Zebrafish Rat
organic acid transport GO:0015849 116 0.020
nucleoside phosphate biosynthetic process GO:1901293 102 0.020
response to molecule of fungal origin GO:0002238 3 0.020
positive regulation of locomotion GO:0040017 102 0.020
regulation of cell activation GO:0050865 50 0.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.020
protein secretion GO:0009306 34 0.020
muscle cell proliferation GO:0033002 84 0.020
vascular process in circulatory system GO:0003018 96 0.020
positive regulation of cytoplasmic transport GO:1903651 32 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.020
response to estradiol GO:0032355 164 0.019
nuclear import GO:0051170 35 0.019
Human
cell cell signaling GO:0007267 335 0.019
regulation of catabolic process GO:0009894 113 0.019
Mouse
nucleoside phosphate catabolic process GO:1901292 140 0.019
gamete generation GO:0007276 124 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
Human Mouse Rat
purine nucleotide biosynthetic process GO:0006164 83 0.019
locomotion GO:0040011 237 0.019
Zebrafish Mouse
anion transport GO:0006820 178 0.019
regulation of mrna 3 end processing GO:0031440 1 0.019
single organism organelle organization GO:1902589 180 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
Human Mouse Rat
cellular response to glucose stimulus GO:0071333 65 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
Rat
regulation of neuron projection development GO:0010975 161 0.018
negative regulation of response to wounding GO:1903035 23 0.018
regulation of cell adhesion GO:0030155 52 0.018
cellular response to abiotic stimulus GO:0071214 85 0.018
positive regulation of necroptotic process GO:0060545 2 0.018
stress activated mapk cascade GO:0051403 35 0.018
positive regulation of jnk cascade GO:0046330 13 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
dephosphorylation GO:0016311 98 0.018
glycosaminoglycan biosynthetic process GO:0006024 4 0.018
regulation of interleukin 12 production GO:0032655 3 0.018
ossification GO:0001503 70 0.018
positive regulation of biomineral tissue development GO:0070169 4 0.017
organic hydroxy compound transport GO:0015850 77 0.017
neuron projection morphogenesis GO:0048812 122 0.017
Zebrafish
organic substance catabolic process GO:1901575 316 0.017
Mouse
heterocycle catabolic process GO:0046700 167 0.017
b cell activation involved in immune response GO:0002312 1 0.017
regulation of proteolysis GO:0030162 66 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
behavior GO:0007610 205 0.017
Mouse
regulation of wnt signaling pathway GO:0030111 8 0.017
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.017
rna stabilization GO:0043489 2 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.017
vitamin d metabolic process GO:0042359 4 0.017
interleukin 6 production GO:0032635 12 0.017
defense response to gram negative bacterium GO:0050829 3 0.017
cellular response to oxygen levels GO:0071453 60 0.017
positive regulation of protein localization to nucleus GO:1900182 15 0.017
epithelial cell differentiation involved in kidney development GO:0035850 3 0.017
Rat
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.017
Rat
adult locomotory behavior GO:0008344 4 0.017
cellular response to carbohydrate stimulus GO:0071322 72 0.016
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
regulation of cellular response to insulin stimulus GO:1900076 16 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
Rat
regulation of alpha beta t cell activation GO:0046634 2 0.016
positive regulation of immune response GO:0050778 42 0.016
positive regulation of ossification GO:0045778 17 0.016
cellular response to amino acid starvation GO:0034198 1 0.016
regulation of cellular component biogenesis GO:0044087 86 0.016
cellular cation homeostasis GO:0030003 180 0.016
regulation of system process GO:0044057 208 0.016
protein localization to organelle GO:0033365 57 0.016
Human
regulation of ion transport GO:0043269 245 0.016
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.016
positive regulation of secretion GO:0051047 140 0.016
immune system development GO:0002520 41 0.016
regulation of synaptic transmission GO:0050804 141 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
Zebrafish Rat
anterior posterior pattern specification GO:0009952 1 0.016
cell activation GO:0001775 97 0.016
fat soluble vitamin biosynthetic process GO:0042362 2 0.016
regeneration GO:0031099 163 0.016
Zebrafish
blood vessel morphogenesis GO:0048514 58 0.016

Stat3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
Human
nervous system disease DOID:863 0 0.029
disease of cellular proliferation DOID:14566 0 0.023
central nervous system disease DOID:331 0 0.021
disease of metabolism DOID:0014667 0 0.020
acquired metabolic disease DOID:0060158 0 0.020
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.017