Rattus norvegicus

15 known processes

Phactr1

phosphatase and actin regulator 1

(Aliases: MGC112561)

Phactr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell projection organization GO:0030030 302 0.104
neuron development GO:0048666 286 0.077
regulation of cellular component organization GO:0051128 368 0.074
regulation of multicellular organismal development GO:2000026 376 0.071
negative regulation of neuron differentiation GO:0045665 62 0.064
regulation of phosphate metabolic process GO:0019220 349 0.063
regulation of nervous system development GO:0051960 264 0.058
regulation of neurogenesis GO:0050767 247 0.057
head development GO:0060322 247 0.056
intracellular signal transduction GO:0035556 314 0.054
neurological system process GO:0050877 219 0.053
regulation of cell differentiation GO:0045595 320 0.051
negative regulation of nervous system development GO:0051961 79 0.050
positive regulation of phosphorus metabolic process GO:0010562 262 0.050
regulation of molecular function GO:0065009 398 0.050
behavior GO:0007610 205 0.050
regulation of apoptotic process GO:0042981 335 0.049
positive regulation of multicellular organismal process GO:0051240 387 0.049
neuron differentiation GO:0030182 368 0.048
positive regulation of cellular component organization GO:0051130 200 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
regulation of neuron differentiation GO:0045664 208 0.047
inorganic ion transmembrane transport GO:0098660 229 0.047
negative regulation of macromolecule metabolic process GO:0010605 260 0.046
regulation of cell development GO:0060284 263 0.046
multi organism reproductive process GO:0044703 262 0.046
neuron projection development GO:0031175 273 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.044
cation transmembrane transport GO:0098655 263 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.043
anatomical structure morphogenesis GO:0009653 298 0.043
regulation of neuron projection development GO:0010975 161 0.042
nucleic acid templated transcription GO:0097659 379 0.042
regulation of cell proliferation GO:0042127 359 0.042
regulation of cell projection organization GO:0031344 175 0.041
calcium ion transport GO:0006816 131 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.040
cognition GO:0050890 92 0.040
cell motility GO:0048870 202 0.039
regulation of rna biosynthetic process GO:2001141 381 0.038
apoptotic process GO:0006915 381 0.038
inorganic cation transmembrane transport GO:0098662 202 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.038
regulation of signal transduction GO:0009966 318 0.037
cellular amine metabolic process GO:0044106 38 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
central nervous system development GO:0007417 311 0.037
regulation of programmed cell death GO:0043067 341 0.037
cellular component movement GO:0006928 248 0.036
nucleotide metabolic process GO:0009117 279 0.036
cellular component biogenesis GO:0044085 368 0.036
Mouse
localization of cell GO:0051674 202 0.036
response to carbohydrate GO:0009743 183 0.036
negative regulation of developmental process GO:0051093 125 0.035
amine metabolic process GO:0009308 38 0.035
brain development GO:0007420 247 0.035
chemical homeostasis GO:0048878 292 0.035
positive regulation of cell differentiation GO:0045597 217 0.035
regulation of rna metabolic process GO:0051252 391 0.034
cellular ketone metabolic process GO:0042180 51 0.034
cellular component assembly GO:0022607 360 0.034
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.034
transmembrane transport GO:0055085 412 0.033
regulation of ion transport GO:0043269 245 0.033
purine containing compound metabolic process GO:0072521 253 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
positive regulation of nervous system development GO:0051962 178 0.033
organophosphate metabolic process GO:0019637 370 0.032
negative regulation of neurogenesis GO:0050768 78 0.032
divalent metal ion transport GO:0070838 132 0.032
negative regulation of multicellular organismal process GO:0051241 203 0.032
response to inorganic substance GO:0010035 377 0.031
transcription dna templated GO:0006351 377 0.031
response to extracellular stimulus GO:0009991 380 0.031
response to metal ion GO:0010038 253 0.031
metal ion transport GO:0030001 289 0.031
programmed cell death GO:0012501 392 0.030
response to estrogen GO:0043627 232 0.030
negative regulation of metabolic process GO:0009892 331 0.030
locomotion GO:0040011 237 0.030
single organism reproductive process GO:0044702 297 0.030
cation transport GO:0006812 382 0.030
regulation of intracellular signal transduction GO:1902531 218 0.030
regulation of phosphorylation GO:0042325 248 0.030
sexual reproduction GO:0019953 148 0.030
multicellular organism reproduction GO:0032504 233 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
positive regulation of developmental process GO:0051094 283 0.029
reproductive process GO:0022414 372 0.029
protein phosphorylation GO:0006468 345 0.029
positive regulation of gene expression GO:0010628 244 0.028
negative regulation of cell development GO:0010721 82 0.028
regulation of transcription dna templated GO:0006355 374 0.028
negative regulation of response to stimulus GO:0048585 155 0.027
rna biosynthetic process GO:0032774 380 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
reproduction GO:0000003 245 0.027
oxoacid metabolic process GO:0043436 290 0.027
gliogenesis GO:0042063 93 0.027
single organism behavior GO:0044708 130 0.027
response to wounding GO:0009611 254 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
single organism catabolic process GO:0044712 283 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
regulation of catalytic activity GO:0050790 304 0.026
negative regulation of cell differentiation GO:0045596 99 0.026
small gtpase mediated signal transduction GO:0007264 36 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
single organism biosynthetic process GO:0044711 342 0.026
negative regulation of gene expression GO:0010629 199 0.026
positive regulation of cell communication GO:0010647 271 0.025
protein complex assembly GO:0006461 263 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
positive regulation of molecular function GO:0044093 230 0.025
organic substance catabolic process GO:1901575 316 0.025
circulatory system process GO:0003013 183 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
cell migration GO:0016477 197 0.025
cellular component morphogenesis GO:0032989 155 0.025
rna metabolic process GO:0016070 406 0.025
carboxylic acid metabolic process GO:0019752 289 0.025
ion homeostasis GO:0050801 212 0.025
monovalent inorganic cation transport GO:0015672 172 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
positive regulation of intracellular signal transduction GO:1902533 138 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
positive regulation of cell projection organization GO:0031346 111 0.024
cellular chemical homeostasis GO:0055082 247 0.024
positive regulation of cell development GO:0010720 176 0.024
response to nutrient levels GO:0031667 370 0.024
negative regulation of cell communication GO:0010648 158 0.024
response to hypoxia GO:0001666 231 0.024
carbohydrate metabolic process GO:0005975 130 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
regulation of membrane potential GO:0042391 110 0.023
organic acid metabolic process GO:0006082 292 0.023
cellular catabolic process GO:0044248 295 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
regulation of cellular component movement GO:0051270 150 0.023
cellular homeostasis GO:0019725 252 0.023
neuronal action potential GO:0019228 35 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.022
ion transmembrane transport GO:0034220 365 0.022
cellular response to stress GO:0033554 269 0.022
response to growth factor GO:0070848 189 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
aging GO:0007568 241 0.022
catabolic process GO:0009056 351 0.022
macromolecular complex subunit organization GO:0043933 339 0.021
Mouse
positive regulation of phosphorylation GO:0042327 177 0.021
transmission of nerve impulse GO:0019226 42 0.021
regulation of system process GO:0044057 208 0.021
glycosyl compound metabolic process GO:1901657 182 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
positive regulation of signaling GO:0023056 270 0.021
cellular cation homeostasis GO:0030003 180 0.021
signal transduction by phosphorylation GO:0023014 144 0.021
cellular response to external stimulus GO:0071496 118 0.021
macromolecule localization GO:0033036 252 0.020
regulation of hydrolase activity GO:0051336 143 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
response to monosaccharide GO:0034284 159 0.020
gamete generation GO:0007276 124 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
ras protein signal transduction GO:0007265 29 0.020
intracellular transport GO:0046907 185 0.020
multi multicellular organism process GO:0044706 138 0.020
response to acid chemical GO:0001101 222 0.020
divalent inorganic cation homeostasis GO:0072507 165 0.020
homeostatic process GO:0042592 331 0.020
action potential GO:0001508 54 0.020
nucleoside phosphate catabolic process GO:1901292 140 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
response to oxygen levels GO:0070482 265 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
learning or memory GO:0007611 90 0.019
cellular response to peptide GO:1901653 133 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
single organism intracellular transport GO:1902582 166 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
tissue development GO:0009888 252 0.019
ribonucleotide catabolic process GO:0009261 136 0.019
vesicle mediated transport GO:0016192 181 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
growth GO:0040007 165 0.019
regulation of anatomical structure size GO:0090066 135 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
peptidyl amino acid modification GO:0018193 126 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
protein localization GO:0008104 191 0.018
protein complex biogenesis GO:0070271 263 0.018
positive regulation of transport GO:0051050 245 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
multicellular organismal signaling GO:0035637 44 0.018
response to decreased oxygen levels GO:0036293 237 0.018
regulation of protein modification process GO:0031399 194 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
macromolecular complex assembly GO:0065003 273 0.018
response to peptide GO:1901652 292 0.018
cell part morphogenesis GO:0032990 123 0.018
response to oxidative stress GO:0006979 186 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
cell growth GO:0016049 104 0.018
nitrogen compound transport GO:0071705 229 0.018
regulation of metal ion transport GO:0010959 118 0.017
potassium ion transport GO:0006813 97 0.017
regulation of catabolic process GO:0009894 113 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
positive regulation of cell death GO:0010942 184 0.017
secretion by cell GO:0032940 248 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
divalent inorganic cation transport GO:0072511 134 0.017
calcium ion homeostasis GO:0055074 162 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
response to nutrient GO:0007584 248 0.017
learning GO:0007612 33 0.017
positive regulation of programmed cell death GO:0043068 157 0.016
cellular macromolecule localization GO:0070727 122 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
blood circulation GO:0008015 183 0.016
cell projection morphogenesis GO:0048858 123 0.016
response to peptide hormone GO:0043434 278 0.016
negative regulation of cell death GO:0060548 229 0.016
circulatory system development GO:0072359 134 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
dephosphorylation GO:0016311 98 0.016
maintenance of location GO:0051235 17 0.016
response to reactive oxygen species GO:0000302 120 0.016
organophosphate catabolic process GO:0046434 148 0.016
negative regulation of signaling GO:0023057 157 0.016
negative regulation of signal transduction GO:0009968 83 0.015
chemosensory behavior GO:0007635 2 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
response to cytokine GO:0034097 215 0.015
purine containing compound catabolic process GO:0072523 138 0.015
regulation of cellular localization GO:0060341 263 0.015
response to hexose GO:0009746 144 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
muscle structure development GO:0061061 87 0.015
regulation of response to external stimulus GO:0032101 106 0.015
motor neuron axon guidance GO:0008045 1 0.015
positive regulation of signal transduction GO:0009967 175 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
developmental process involved in reproduction GO:0003006 159 0.015
forebrain development GO:0030900 98 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
secretion GO:0046903 307 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
olfactory behavior GO:0042048 2 0.014
sequestering of calcium ion GO:0051208 8 0.014
cardiovascular system development GO:0072358 134 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
cellular ion homeostasis GO:0006873 184 0.014
response to alkaloid GO:0043279 132 0.014
regulation of ion transmembrane transport GO:0034765 121 0.014
axon development GO:0061564 96 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
negative regulation of transport GO:0051051 136 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
regulation of blood circulation GO:1903522 110 0.014
regulation of cell migration GO:0030334 128 0.013
organelle organization GO:0006996 266 0.013
Mouse
negative regulation of cellular component organization GO:0051129 83 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
protein complex subunit organization GO:0071822 302 0.013
Mouse
mapk cascade GO:0000165 140 0.013
regulation of transmembrane transport GO:0034762 122 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
cation homeostasis GO:0055080 195 0.013
regulation of cell growth GO:0001558 85 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
nucleoside catabolic process GO:0009164 126 0.013
sequestering of metal ion GO:0051238 9 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
regulation of protein metabolic process GO:0051246 289 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
alternative mrna splicing via spliceosome GO:0000380 4 0.013
response to purine containing compound GO:0014074 126 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
response to glucose GO:0009749 136 0.013
dna metabolic process GO:0006259 96 0.013
positive regulation of protein modification process GO:0031401 142 0.013
cellular response to mechanical stimulus GO:0071260 48 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
regulation of homeostatic process GO:0032844 101 0.012
male gamete generation GO:0048232 99 0.012
epithelium development GO:0060429 96 0.012
response to ethanol GO:0045471 162 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
regulation of blood pressure GO:0008217 83 0.012
nucleotide catabolic process GO:0009166 139 0.012
regulation of growth GO:0040008 105 0.012
glial cell differentiation GO:0010001 65 0.012
response to estradiol GO:0032355 164 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of secretion by cell GO:1903530 208 0.012
eye morphogenesis GO:0048592 4 0.012
multicellular organism growth GO:0035264 1 0.012
negative regulation of cell projection organization GO:0031345 50 0.012
cytoplasmic transport GO:0016482 115 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
neuron death GO:0070997 127 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
regulation of calcium ion transport GO:0051924 77 0.012
lipid storage GO:0019915 1 0.012
axis specification GO:0009798 4 0.012
response to calcium ion GO:0051592 59 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
heart morphogenesis GO:0003007 3 0.012
intracellular protein transport GO:0006886 79 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
response to camp GO:0051591 91 0.012
axon ensheathment GO:0008366 40 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
organic acid biosynthetic process GO:0016053 83 0.012
response to glucocorticoid GO:0051384 223 0.012
muscle system process GO:0003012 115 0.012
gland development GO:0048732 155 0.012
protein oligomerization GO:0051259 191 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
regulation of blood vessel size GO:0050880 89 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
regulation of neuron death GO:1901214 115 0.011
biological adhesion GO:0022610 110 0.011
protein transport GO:0015031 132 0.011
taxis GO:0042330 67 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
cellular protein localization GO:0034613 122 0.011
establishment of protein localization GO:0045184 141 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
spermatogenesis GO:0007283 99 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
sensory perception of pain GO:0019233 73 0.011
lipid metabolic process GO:0006629 283 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
heart process GO:0003015 57 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
heart contraction GO:0060047 57 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
rhythmic process GO:0048511 156 0.011
membrane depolarization during action potential GO:0086010 1 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
response to organophosphorus GO:0046683 102 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
calcium ion transmembrane transport GO:0070588 70 0.011
response to lipopolysaccharide GO:0032496 191 0.011
vascular process in circulatory system GO:0003018 96 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.011
regulation of ion homeostasis GO:2000021 63 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
nucleoside metabolic process GO:0009116 179 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
negative regulation of molecular function GO:0044092 133 0.011
regulation of hormone levels GO:0010817 187 0.010
cell adhesion GO:0007155 110 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
aromatic compound catabolic process GO:0019439 168 0.010
regulation of gtpase activity GO:0043087 57 0.010
heterocycle catabolic process GO:0046700 167 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
olfactory learning GO:0008355 1 0.010
purine ribonucleotide biosynthetic process GO:0009152 81 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
response to external biotic stimulus GO:0043207 221 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
negative regulation of growth GO:0045926 37 0.010
cellular lipid metabolic process GO:0044255 208 0.010
response to corticosteroid GO:0031960 235 0.010
sodium ion transmembrane transport GO:0035725 67 0.010
salivary gland development GO:0007431 3 0.010
glucose homeostasis GO:0042593 75 0.010

Phactr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.033
brain disease DOID:936 0 0.033
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
disease of metabolism DOID:0014667 0 0.014
epilepsy syndrome DOID:1826 0 0.012
inherited metabolic disorder DOID:655 0 0.011