Rattus norvegicus

0 known processes

Sema3d

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D

Sema3d biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.084
reproductive process GO:0022414 372 0.081
response to nutrient levels GO:0031667 370 0.067
regulation of multicellular organismal development GO:2000026 376 0.066
Rat
regulation of cell proliferation GO:0042127 359 0.064
programmed cell death GO:0012501 392 0.056
Rat
multi organism reproductive process GO:0044703 262 0.054
regulation of programmed cell death GO:0043067 341 0.052
response to inorganic substance GO:0010035 377 0.051
response to extracellular stimulus GO:0009991 380 0.050
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.050
cellular response to oxygen containing compound GO:1901701 386 0.048
regulation of molecular function GO:0065009 398 0.048
positive regulation of biosynthetic process GO:0009891 319 0.047
transcription from rna polymerase ii promoter GO:0006366 252 0.047
rna biosynthetic process GO:0032774 380 0.046
regulation of cell differentiation GO:0045595 320 0.045
Rat
response to nutrient GO:0007584 248 0.044
reproduction GO:0000003 245 0.043
negative regulation of metabolic process GO:0009892 331 0.042
multicellular organismal reproductive process GO:0048609 233 0.042
regulation of signal transduction GO:0009966 318 0.042
regulation of rna biosynthetic process GO:2001141 381 0.041
negative regulation of macromolecule metabolic process GO:0010605 260 0.040
single organism reproductive process GO:0044702 297 0.039
anatomical structure morphogenesis GO:0009653 298 0.039
Rat Fly
regulation of cellular component organization GO:0051128 368 0.039
Rat
regulation of apoptotic process GO:0042981 335 0.038
intracellular signal transduction GO:0035556 314 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
protein phosphorylation GO:0006468 345 0.037
transcription dna templated GO:0006351 377 0.036
positive regulation of multicellular organismal process GO:0051240 387 0.036
carboxylic acid metabolic process GO:0019752 289 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
response to estrogen GO:0043627 232 0.035
apoptotic process GO:0006915 381 0.035
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.035
positive regulation of gene expression GO:0010628 244 0.035
negative regulation of cell proliferation GO:0008285 119 0.035
cellular component biogenesis GO:0044085 368 0.035
organophosphate metabolic process GO:0019637 370 0.035
regulation of transcription dna templated GO:0006355 374 0.034
response to biotic stimulus GO:0009607 226 0.034
nucleic acid templated transcription GO:0097659 379 0.034
response to bacterium GO:0009617 200 0.034
organic acid metabolic process GO:0006082 292 0.033
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
response to oxidative stress GO:0006979 186 0.033
regulation of phosphate metabolic process GO:0019220 349 0.033
negative regulation of cell death GO:0060548 229 0.032
regulation of neuron differentiation GO:0045664 208 0.032
Rat
positive regulation of cell proliferation GO:0008284 249 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
neuron development GO:0048666 286 0.031
Rat Fly
negative regulation of cellular metabolic process GO:0031324 281 0.031
response to external biotic stimulus GO:0043207 221 0.031
multicellular organism reproduction GO:0032504 233 0.031
cellular response to endogenous stimulus GO:0071495 377 0.030
secretion GO:0046903 307 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
response to oxygen levels GO:0070482 265 0.030
positive regulation of developmental process GO:0051094 283 0.030
regulation of nervous system development GO:0051960 264 0.029
Rat
regulation of intracellular signal transduction GO:1902531 218 0.029
cardiovascular system development GO:0072358 134 0.029
regulation of phosphorylation GO:0042325 248 0.029
central nervous system development GO:0007417 311 0.028
response to acid chemical GO:0001101 222 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
regulation of neurogenesis GO:0050767 247 0.028
Rat
cell morphogenesis GO:0000902 142 0.028
Rat Fly
macromolecule localization GO:0033036 252 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
neuron differentiation GO:0030182 368 0.027
Rat Fly
positive regulation of rna biosynthetic process GO:1902680 197 0.027
biological adhesion GO:0022610 110 0.027
cellular component assembly GO:0022607 360 0.027
cell projection organization GO:0030030 302 0.027
Rat Fly
locomotion GO:0040011 237 0.026
Rat Fly
oxoacid metabolic process GO:0043436 290 0.026
response to peptide hormone GO:0043434 278 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
tissue development GO:0009888 252 0.026
protein complex subunit organization GO:0071822 302 0.026
cellular response to lipid GO:0071396 201 0.026
rna metabolic process GO:0016070 406 0.026
negative regulation of molecular function GO:0044092 133 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
amine metabolic process GO:0009308 38 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
ion transmembrane transport GO:0034220 365 0.026
regulation of catalytic activity GO:0050790 304 0.025
positive regulation of signaling GO:0023056 270 0.025
cellular amine metabolic process GO:0044106 38 0.025
regulation of protein metabolic process GO:0051246 289 0.025
response to cytokine GO:0034097 215 0.025
cellular ketone metabolic process GO:0042180 51 0.025
neurological system process GO:0050877 219 0.025
chemical homeostasis GO:0048878 292 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
response to other organism GO:0051707 220 0.024
regulation of secretion GO:0051046 224 0.024
negative regulation of developmental process GO:0051093 125 0.024
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.024
single organism biosynthetic process GO:0044711 342 0.024
response to growth factor GO:0070848 189 0.024
aging GO:0007568 241 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
cellular catabolic process GO:0044248 295 0.023
cell cell signaling GO:0007267 335 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
lipid metabolic process GO:0006629 283 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
protein complex assembly GO:0006461 263 0.023
homeostatic process GO:0042592 331 0.023
regulation of rna metabolic process GO:0051252 391 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
multi multicellular organism process GO:0044706 138 0.022
positive regulation of molecular function GO:0044093 230 0.022
regulation of cell development GO:0060284 263 0.022
Rat
positive regulation of cell death GO:0010942 184 0.022
response to peptide GO:1901652 292 0.022
regulation of protein modification process GO:0031399 194 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
organic substance catabolic process GO:1901575 316 0.022
negative regulation of gene expression GO:0010629 199 0.022
protein complex biogenesis GO:0070271 263 0.022
cell adhesion GO:0007155 110 0.022
response to vitamin GO:0033273 131 0.022
positive regulation of cellular component organization GO:0051130 200 0.021
rhythmic process GO:0048511 156 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
negative regulation of signaling GO:0023057 157 0.021
response to lipopolysaccharide GO:0032496 191 0.021
response to molecule of bacterial origin GO:0002237 194 0.021
response to estradiol GO:0032355 164 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
response to metal ion GO:0010038 253 0.021
cell migration GO:0016477 197 0.021
cellular component movement GO:0006928 248 0.020
Rat Fly
ribonucleotide metabolic process GO:0009259 231 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
organelle organization GO:0006996 266 0.020
kidney development GO:0001822 67 0.020
transmembrane transport GO:0055085 412 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
single organism catabolic process GO:0044712 283 0.020
macromolecular complex assembly GO:0065003 273 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
positive regulation of transport GO:0051050 245 0.020
immune system process GO:0002376 204 0.020
positive regulation of nervous system development GO:0051962 178 0.020
ras protein signal transduction GO:0007265 29 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.020
positive regulation of cell communication GO:0010647 271 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
muscle cell proliferation GO:0033002 84 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
cation transport GO:0006812 382 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
negative regulation of cell communication GO:0010648 158 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
response to purine containing compound GO:0014074 126 0.019
response to wounding GO:0009611 254 0.019
cell motility GO:0048870 202 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
catabolic process GO:0009056 351 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
Rat
positive regulation of neurogenesis GO:0050769 165 0.018
positive regulation of cell development GO:0010720 176 0.018
gastrulation GO:0007369 2 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
cellular homeostasis GO:0019725 252 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
nucleotide metabolic process GO:0009117 279 0.017
blood circulation GO:0008015 183 0.017
protein oligomerization GO:0051259 191 0.017
response to organophosphorus GO:0046683 102 0.017
cellular response to stress GO:0033554 269 0.017
Fly
response to hypoxia GO:0001666 231 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
response to camp GO:0051591 91 0.017
metal ion transport GO:0030001 289 0.017
reproductive structure development GO:0048608 128 0.017
nucleoside metabolic process GO:0009116 179 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
circulatory system development GO:0072359 134 0.017
single organism intracellular transport GO:1902582 166 0.017
female pregnancy GO:0007565 122 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
cellular response to growth factor stimulus GO:0071363 162 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
salivary gland development GO:0007431 3 0.016
anion transport GO:0006820 178 0.016
synaptic transmission GO:0007268 235 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
behavior GO:0007610 205 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
secretion by cell GO:0032940 248 0.016
cellular lipid metabolic process GO:0044255 208 0.016
circulatory system process GO:0003013 183 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
brain development GO:0007420 247 0.016
defense response GO:0006952 194 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
response to carbohydrate GO:0009743 183 0.016
nitrogen compound transport GO:0071705 229 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.015
proteolysis GO:0006508 175 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
Rat Fly
cellular response to hormone stimulus GO:0032870 247 0.015
localization of cell GO:0051674 202 0.015
regulation of secretion by cell GO:1903530 208 0.015
positive regulation of protein modification process GO:0031401 142 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
regulation of system process GO:0044057 208 0.015
regulation of hydrolase activity GO:0051336 143 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
cellular cation homeostasis GO:0030003 180 0.015
calcium ion homeostasis GO:0055074 162 0.015
cation transmembrane transport GO:0098655 263 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
vesicle mediated transport GO:0016192 181 0.015
cellular chemical homeostasis GO:0055082 247 0.015
cell projection morphogenesis GO:0048858 123 0.014
Rat Fly
head development GO:0060322 247 0.014
reproductive system development GO:0061458 128 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
salivary gland morphogenesis GO:0007435 1 0.014
regulation of neuron projection development GO:0010975 161 0.014
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
Rat
eye morphogenesis GO:0048592 4 0.014
multicellular organism growth GO:0035264 1 0.014
ion homeostasis GO:0050801 212 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
intracellular transport GO:0046907 185 0.014
wound healing GO:0042060 122 0.014
sexual reproduction GO:0019953 148 0.014
developmental process involved in reproduction GO:0003006 159 0.014
blood vessel development GO:0001568 69 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
heterocycle catabolic process GO:0046700 167 0.014
regulation of hormone levels GO:0010817 187 0.013
cellular response to acid chemical GO:0071229 75 0.013
purine containing compound metabolic process GO:0072521 253 0.013
neuron projection development GO:0031175 273 0.013
Rat Fly
growth GO:0040007 165 0.013
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.013
Rat
regulation of cellular localization GO:0060341 263 0.013
response to decreased oxygen levels GO:0036293 237 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
regulation of g0 to g1 transition GO:0070316 3 0.013
blood vessel morphogenesis GO:0048514 58 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
regulation of anatomical structure size GO:0090066 135 0.013
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
angiogenesis GO:0001525 53 0.013
response to reactive oxygen species GO:0000302 120 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
axis specification GO:0009798 4 0.013
response to mechanical stimulus GO:0009612 134 0.013
mapk cascade GO:0000165 140 0.013
regulation of mesenchymal cell proliferation GO:0010464 4 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
response to hexose GO:0009746 144 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
regulation of cell projection organization GO:0031344 175 0.012
Rat
carbohydrate metabolic process GO:0005975 130 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
urogenital system development GO:0001655 78 0.012
regulation of kinase activity GO:0043549 117 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
negative regulation of transport GO:0051051 136 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
heart morphogenesis GO:0003007 3 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
response to glucocorticoid GO:0051384 223 0.012
peptidyl amino acid modification GO:0018193 126 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
nucleotide catabolic process GO:0009166 139 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
anterior posterior pattern specification GO:0009952 1 0.012
divalent inorganic cation transport GO:0072511 134 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
Rat
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
gamete generation GO:0007276 124 0.012
single organism organelle organization GO:1902589 180 0.012
response to corticosteroid GO:0031960 235 0.012
divalent metal ion transport GO:0070838 132 0.012
regulation of immune system process GO:0002682 123 0.012
skeletal system development GO:0001501 41 0.012
development of primary sexual characteristics GO:0045137 107 0.012
vasculature development GO:0001944 70 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
oxidation reduction process GO:0055114 304 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
cation homeostasis GO:0055080 195 0.012
response to ketone GO:1901654 182 0.012
cellular response to organic cyclic compound GO:0071407 202 0.011
response to alkaloid GO:0043279 132 0.011
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
response to radiation GO:0009314 137 0.011
negative regulation of signal transduction GO:0009968 83 0.011
neuron death GO:0070997 127 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
embryonic skeletal system development GO:0048706 3 0.011
regulation of cell motility GO:2000145 131 0.011
cell activation GO:0001775 97 0.011
neuron projection morphogenesis GO:0048812 122 0.011
Rat Fly
immune response GO:0006955 104 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
sensory perception GO:0007600 101 0.011
mesenchymal cell proliferation GO:0010463 4 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
cellular response to peptide GO:1901653 133 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
tube development GO:0035295 89 0.011
lipid storage GO:0019915 1 0.011
cellular response to external stimulus GO:0071496 118 0.011
fatty acid metabolic process GO:0006631 99 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
regulation of transferase activity GO:0051338 123 0.011
sex differentiation GO:0007548 113 0.011
cellular ion homeostasis GO:0006873 184 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
positive regulation of endothelial cell migration GO:0010595 4 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
gonad development GO:0008406 104 0.011
regulation of locomotion GO:0040012 148 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
response to glucose GO:0009749 136 0.011
cell type specific apoptotic process GO:0097285 134 0.011
organic anion transport GO:0015711 132 0.011
camera type eye morphogenesis GO:0048593 2 0.011
metal ion homeostasis GO:0055065 186 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
regulation of growth GO:0040008 105 0.011
Rat
cell part morphogenesis GO:0032990 123 0.011
Rat Fly
cellular component morphogenesis GO:0032989 155 0.011
Rat Fly
regulation of ion transport GO:0043269 245 0.011
rho protein signal transduction GO:0007266 11 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
calcium ion transport GO:0006816 131 0.010
positive regulation of immunoglobulin production GO:0002639 4 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
response to hydrogen peroxide GO:0042542 89 0.010
organophosphate catabolic process GO:0046434 148 0.010
olfactory behavior GO:0042048 2 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
gland development GO:0048732 155 0.010

Sema3d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.016
central nervous system disease DOID:331 0 0.012
sensory system disease DOID:0050155 0 0.012