Rattus norvegicus

41 known processes

Cyp27a1

cytochrome P450, family 27, subfamily a, polypeptide 1

(Aliases: P450C27,Cyp27)

Cyp27a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.684
Rat
oxoacid metabolic process GO:0043436 290 0.451
Rat
cellular lipid metabolic process GO:0044255 208 0.365
organic acid metabolic process GO:0006082 292 0.355
Rat
oxidation reduction process GO:0055114 304 0.350
monocarboxylic acid metabolic process GO:0032787 152 0.318
fatty acid metabolic process GO:0006631 99 0.265
cellular response to oxygen containing compound GO:1901701 386 0.229
Rat
small molecule biosynthetic process GO:0044283 124 0.140
response to peptide GO:1901652 292 0.118
Rat
organic acid biosynthetic process GO:0016053 83 0.117
cellular response to peptide GO:1901653 133 0.114
Rat
response to extracellular stimulus GO:0009991 380 0.110
Rat
single organism biosynthetic process GO:0044711 342 0.109
lipid metabolic process GO:0006629 283 0.109
catabolic process GO:0009056 351 0.105
response to inorganic substance GO:0010035 377 0.101
Rat
aging GO:0007568 241 0.100
fatty acid derivative metabolic process GO:1901568 38 0.100
cellular response to endogenous stimulus GO:0071495 377 0.096
Rat
response to insulin GO:0032868 133 0.087
Rat
unsaturated fatty acid metabolic process GO:0033559 39 0.086
reproductive process GO:0022414 372 0.077
Rat
response to peptide hormone GO:0043434 278 0.073
Rat
single organism catabolic process GO:0044712 283 0.073
response to nutrient levels GO:0031667 370 0.069
Rat
response to xenobiotic stimulus GO:0009410 23 0.069
steroid metabolic process GO:0008202 73 0.067
organic hydroxy compound metabolic process GO:1901615 115 0.066
cellular catabolic process GO:0044248 295 0.063
chlorinated hydrocarbon metabolic process GO:0042196 4 0.061
carboxylic acid biosynthetic process GO:0046394 83 0.058
negative regulation of biosynthetic process GO:0009890 168 0.058
regulation of cellular ketone metabolic process GO:0010565 27 0.057
lipid biosynthetic process GO:0008610 128 0.057
cellular hormone metabolic process GO:0034754 49 0.055
Rat
liver development GO:0001889 90 0.054
cellular response to nitrogen compound GO:1901699 210 0.053
Rat
defense response GO:0006952 194 0.053
Rat
response to metal ion GO:0010038 253 0.052
Rat
cellular ketone metabolic process GO:0042180 51 0.052
Rat
response to external biotic stimulus GO:0043207 221 0.052
Rat
organic substance catabolic process GO:1901575 316 0.051
regulation of programmed cell death GO:0043067 341 0.051
response to ethanol GO:0045471 162 0.050
secretion GO:0046903 307 0.049
response to ketone GO:1901654 182 0.049
Rat
homeostatic process GO:0042592 331 0.049
cellular response to organonitrogen compound GO:0071417 197 0.049
Rat
response to glucocorticoid GO:0051384 223 0.049
Rat
hormone metabolic process GO:0042445 69 0.048
Rat
icosanoid metabolic process GO:0006690 38 0.048
linoleic acid metabolic process GO:0043651 4 0.047
regulation of secretion by cell GO:1903530 208 0.047
regulation of cell proliferation GO:0042127 359 0.046
organic hydroxy compound biosynthetic process GO:1901617 51 0.045
apoptotic process GO:0006915 381 0.045
single organism carbohydrate metabolic process GO:0044723 118 0.044
cellular amino acid metabolic process GO:0006520 107 0.043
response to carbohydrate GO:0009743 183 0.043
Rat
cellular response to xenobiotic stimulus GO:0071466 19 0.042
sulfur compound metabolic process GO:0006790 70 0.041
retinal metabolic process GO:0042574 3 0.041
cellular response to peptide hormone stimulus GO:0071375 120 0.041
Rat
coenzyme metabolic process GO:0006732 86 0.040
blood circulation GO:0008015 183 0.039
Rat
protein complex subunit organization GO:0071822 302 0.039
hepaticobiliary system development GO:0061008 90 0.039
regulation of hormone levels GO:0010817 187 0.039
Rat
naphthalene metabolic process GO:0018931 2 0.039
secretion by cell GO:0032940 248 0.038
regulation of secretion GO:0051046 224 0.038
response to hexose GO:0009746 144 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
Rat
reproductive system development GO:0061458 128 0.037
Rat
response to calcium ion GO:0051592 59 0.037
response to oxidative stress GO:0006979 186 0.037
Rat
terpenoid metabolic process GO:0006721 37 0.036
monocarboxylic acid biosynthetic process GO:0072330 48 0.036
macromolecular complex subunit organization GO:0043933 339 0.035
response to monosaccharide GO:0034284 159 0.035
Rat
neurological system process GO:0050877 219 0.035
cellular response to molecule of bacterial origin GO:0071219 56 0.034
Rat
alcohol metabolic process GO:0006066 77 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
androgen metabolic process GO:0008209 14 0.034
Rat
response to toxic substance GO:0009636 133 0.034
Rat
amine metabolic process GO:0009308 38 0.034
single organism reproductive process GO:0044702 297 0.033
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
naphthalene containing compound metabolic process GO:0090420 2 0.032
regulation of apoptotic process GO:0042981 335 0.032
negative regulation of cellular metabolic process GO:0031324 281 0.032
programmed cell death GO:0012501 392 0.031
carbohydrate metabolic process GO:0005975 130 0.031
cellular component assembly GO:0022607 360 0.031
response to nutrient GO:0007584 248 0.031
Rat
cofactor metabolic process GO:0051186 95 0.031
response to glucose GO:0009749 136 0.031
cellular response to reactive oxygen species GO:0034614 55 0.030
negative regulation of signaling GO:0023057 157 0.030
regulation of intracellular signal transduction GO:1902531 218 0.030
immune response GO:0006955 104 0.030
Rat
lipid catabolic process GO:0016042 46 0.030
cellular response to extracellular stimulus GO:0031668 73 0.029
Rat
cellular response to lipid GO:0071396 201 0.029
Rat
response to corticosteroid GO:0031960 235 0.029
Rat
response to biotic stimulus GO:0009607 226 0.029
Rat
response to oxygen levels GO:0070482 265 0.028
cellular component biogenesis GO:0044085 368 0.028
positive regulation of cell communication GO:0010647 271 0.028
regulation of molecular function GO:0065009 398 0.028
macromolecule localization GO:0033036 252 0.028
organophosphate metabolic process GO:0019637 370 0.028
protein oligomerization GO:0051259 191 0.028
cellular amine metabolic process GO:0044106 38 0.027
diterpenoid metabolic process GO:0016101 33 0.027
chemical homeostasis GO:0048878 292 0.027
regulation of signal transduction GO:0009966 318 0.027
response to estrogen GO:0043627 232 0.027
Rat
multicellular organism reproduction GO:0032504 233 0.027
Rat
lipid oxidation GO:0034440 30 0.027
response to other organism GO:0051707 220 0.027
Rat
isoprenoid metabolic process GO:0006720 45 0.026
small molecule catabolic process GO:0044282 59 0.026
response to acid chemical GO:0001101 222 0.026
Rat
multi multicellular organism process GO:0044706 138 0.026
Rat
protein complex assembly GO:0006461 263 0.026
response to reactive oxygen species GO:0000302 120 0.025
Rat
response to wounding GO:0009611 254 0.025
regulation of system process GO:0044057 208 0.024
macromolecular complex assembly GO:0065003 273 0.024
inflammatory response GO:0006954 150 0.024
circulatory system process GO:0003013 183 0.024
Rat
cellular response to stress GO:0033554 269 0.024
Rat
retinoic acid receptor signaling pathway GO:0048384 7 0.024
xenobiotic metabolic process GO:0006805 19 0.024
icosanoid biosynthetic process GO:0046456 18 0.024
regulation of membrane potential GO:0042391 110 0.024
action potential GO:0001508 54 0.024
brain development GO:0007420 247 0.024
Rat
multi organism reproductive process GO:0044703 262 0.024
Rat
multicellular organismal reproductive process GO:0048609 233 0.023
Rat
positive regulation of gene expression GO:0010628 244 0.023
fatty acid biosynthetic process GO:0006633 33 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
Rat
transmembrane transport GO:0055085 412 0.023
intracellular signal transduction GO:0035556 314 0.023
regulation of cellular localization GO:0060341 263 0.022
intracellular receptor signaling pathway GO:0030522 35 0.022
glycerolipid metabolic process GO:0046486 67 0.022
positive regulation of signaling GO:0023056 270 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
regulation of rna metabolic process GO:0051252 391 0.021
acylglycerol metabolic process GO:0006639 21 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
pyridine containing compound metabolic process GO:0072524 32 0.021
negative regulation of metabolic process GO:0009892 331 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
proteolysis GO:0006508 175 0.021
protein homooligomerization GO:0051260 91 0.021
regulation of response to stress GO:0080134 126 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
regulation of protein metabolic process GO:0051246 289 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
rna metabolic process GO:0016070 406 0.020
organ regeneration GO:0031100 101 0.020
lipid storage GO:0019915 1 0.019
cellular response to insulin stimulus GO:0032869 81 0.019
response to vitamin GO:0033273 131 0.019
Rat
regulation of transcription dna templated GO:0006355 374 0.019
maintenance of location GO:0051235 17 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
cellular response to external stimulus GO:0071496 118 0.019
Rat
cellular response to biotic stimulus GO:0071216 59 0.019
Rat
nucleic acid templated transcription GO:0097659 379 0.019
triglyceride metabolic process GO:0006641 21 0.019
positive regulation of transport GO:0051050 245 0.019
response to organophosphorus GO:0046683 102 0.019
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.019
negative regulation of transport GO:0051051 136 0.018
negative regulation of protein import into nucleus translocation GO:0033159 1 0.018
reproduction GO:0000003 245 0.018
Rat
negative regulation of secretion GO:0051048 82 0.018
cation transport GO:0006812 382 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
response to hypoxia GO:0001666 231 0.018
arachidonic acid metabolic process GO:0019369 20 0.018
negative regulation of cell death GO:0060548 229 0.018
phenol containing compound metabolic process GO:0018958 30 0.018
Rat
positive regulation of cellular component organization GO:0051130 200 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
neuron development GO:0048666 286 0.018
cellular macromolecule localization GO:0070727 122 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
cellular response to oxidative stress GO:0034599 76 0.017
fatty acid oxidation GO:0019395 29 0.017
regeneration GO:0031099 163 0.017
regulation of cell differentiation GO:0045595 320 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
Rat
acute inflammatory response GO:0002526 58 0.017
cell projection organization GO:0030030 302 0.017
rhythmic process GO:0048511 156 0.017
lauric acid metabolic process GO:0048252 4 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
hormone transport GO:0009914 121 0.017
positive regulation of cell death GO:0010942 184 0.017
cellular response to alcohol GO:0097306 87 0.017
central nervous system development GO:0007417 311 0.017
Rat
positive regulation of cell proliferation GO:0008284 249 0.017
cellular response to cytokine stimulus GO:0071345 127 0.017
Rat
alkaloid metabolic process GO:0009820 3 0.017
negative regulation of innate immune response GO:0045824 4 0.017
intracellular transport GO:0046907 185 0.017
transcription dna templated GO:0006351 377 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
glutathione metabolic process GO:0006749 15 0.016
response to decreased oxygen levels GO:0036293 237 0.016
lipid transport GO:0006869 61 0.016
cellular response to nutrient levels GO:0031669 60 0.016
Rat
positive regulation of nervous system development GO:0051962 178 0.016
protein phosphorylation GO:0006468 345 0.016
positive regulation of defense response GO:0031349 37 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
regulation of lipid metabolic process GO:0019216 68 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
protein localization GO:0008104 191 0.016
gonad development GO:0008406 104 0.016
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.016
Rat
response to cytokine GO:0034097 215 0.015
Rat
negative regulation of cell communication GO:0010648 158 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
alpha amino acid metabolic process GO:1901605 71 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
ion transmembrane transport GO:0034220 365 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
cellular homeostasis GO:0019725 252 0.015
developmental process involved in reproduction GO:0003006 159 0.015
Rat
heterocycle catabolic process GO:0046700 167 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
protein complex biogenesis GO:0070271 263 0.015
cation homeostasis GO:0055080 195 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
peptide transport GO:0015833 97 0.015
amide transport GO:0042886 105 0.015
positive regulation of secretion GO:0051047 140 0.015
response to bacterium GO:0009617 200 0.015
Rat
response to amino acid GO:0043200 75 0.015
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
head development GO:0060322 247 0.015
Rat
maternal process involved in female pregnancy GO:0060135 38 0.015
Rat
regulation of phosphorylation GO:0042325 248 0.015
long chain fatty acid metabolic process GO:0001676 32 0.014
jak stat cascade GO:0007259 26 0.014
protein transport GO:0015031 132 0.014
regulation of ion transport GO:0043269 245 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
positive regulation of developmental process GO:0051094 283 0.014
cellular amide metabolic process GO:0043603 44 0.014
carboxylic acid transport GO:0046942 115 0.014
regulation of catalytic activity GO:0050790 304 0.014
drug catabolic process GO:0042737 1 0.014
lipid localization GO:0010876 62 0.014
axis specification GO:0009798 4 0.014
signal release GO:0023061 145 0.014
regulation of protein modification process GO:0031399 194 0.014
learning or memory GO:0007611 90 0.014
single organism behavior GO:0044708 130 0.014
halogenated hydrocarbon metabolic process GO:0042197 4 0.014
response to radiation GO:0009314 137 0.014
Rat
reproductive structure development GO:0048608 128 0.014
Rat
establishment of protein localization GO:0045184 141 0.014
response to starvation GO:0042594 59 0.014
Rat
positive regulation of cell differentiation GO:0045597 217 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.013
positive regulation of signal transduction GO:0009967 175 0.013
carboxylic acid catabolic process GO:0046395 49 0.013
fluorene metabolic process GO:0018917 1 0.013
neuron differentiation GO:0030182 368 0.013
metal ion transport GO:0030001 289 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
regulation of neurogenesis GO:0050767 247 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
neuronal action potential GO:0019228 35 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
negative regulation of secretion by cell GO:1903531 72 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
male gonad development GO:0008584 59 0.013
Rat
steroid biosynthetic process GO:0006694 48 0.013
regulation of peptide transport GO:0090087 87 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
muscle cell proliferation GO:0033002 84 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
cellular lipid catabolic process GO:0044242 37 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
Rat
limbic system development GO:0021761 38 0.012
Rat
cholesterol homeostasis GO:0042632 3 0.012
nicotine metabolic process GO:0018933 1 0.012
nitrogen compound transport GO:0071705 229 0.012
hormone secretion GO:0046879 115 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
response to lipopolysaccharide GO:0032496 191 0.012
Rat
positive regulation of transcription dna templated GO:0045893 197 0.012
regulation of cell development GO:0060284 263 0.012
metal ion homeostasis GO:0055065 186 0.012
response to temperature stimulus GO:0009266 94 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
male sex differentiation GO:0046661 64 0.012
Rat
cellular protein localization GO:0034613 122 0.012
insulin secretion GO:0030073 69 0.012
potassium ion transport GO:0006813 97 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
lipid modification GO:0030258 52 0.012
cytokine biosynthetic process GO:0042089 3 0.012
purine containing compound metabolic process GO:0072521 253 0.012
Rat
regulation of peptide hormone secretion GO:0090276 80 0.012
cell type specific apoptotic process GO:0097285 134 0.012
pallium development GO:0021543 42 0.012
Rat
embryonic pattern specification GO:0009880 1 0.012
response to camp GO:0051591 91 0.012
Rat
development of primary sexual characteristics GO:0045137 107 0.012
Rat
regulation of peptide secretion GO:0002791 82 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.011
regulation of hormone secretion GO:0046883 106 0.011
negative regulation of gene expression GO:0010629 199 0.011
regulation of defense response GO:0031347 68 0.011
anion transport GO:0006820 178 0.011
response to purine containing compound GO:0014074 126 0.011
Rat
ovulation cycle GO:0042698 67 0.011
cellular cation homeostasis GO:0030003 180 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
peptide hormone secretion GO:0030072 84 0.011
ion homeostasis GO:0050801 212 0.011
positive regulation of cell development GO:0010720 176 0.011
membrane organization GO:0061024 94 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
response to ionizing radiation GO:0010212 59 0.011
Rat
thioester metabolic process GO:0035383 28 0.011
retinoid metabolic process GO:0001523 24 0.011
regulation of gluconeogenesis GO:0006111 4 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
regulation of insulin secretion GO:0050796 65 0.011
regulation of cell projection organization GO:0031344 175 0.011
sex differentiation GO:0007548 113 0.011
Rat
positive regulation of molecular function GO:0044093 230 0.011
secondary metabolic process GO:0019748 15 0.011
single organism intracellular transport GO:1902582 166 0.011
organic acid transport GO:0015849 116 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
dna metabolic process GO:0006259 96 0.011
cardiac conduction GO:0061337 2 0.011
response to growth factor GO:0070848 189 0.011
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
calcium ion homeostasis GO:0055074 162 0.010
cytoplasmic transport GO:0016482 115 0.010
muscle contraction GO:0006936 88 0.010
regulation of cellular component organization GO:0051128 368 0.010
cellular modified amino acid metabolic process GO:0006575 61 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010
acetyl coa metabolic process GO:0006084 17 0.010
cellular response to nutrient GO:0031670 30 0.010
Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
female pregnancy GO:0007565 122 0.010
Rat
cellular chemical homeostasis GO:0055082 247 0.010
cellular response to lipopolysaccharide GO:0071222 55 0.010
Rat
regulation of immune system process GO:0002682 123 0.010
transmission of nerve impulse GO:0019226 42 0.010
development of primary male sexual characteristics GO:0046546 59 0.010
Rat
glucose metabolic process GO:0006006 52 0.010
response to activity GO:0014823 73 0.010

Cyp27a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.037
Human
inherited metabolic disorder DOID:655 0 0.014
Human
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
cardiovascular system disease DOID:1287 0 0.011