Rattus norvegicus

0 known processes

Ikbkg

inhibitor of kappaB kinase gamma

(Aliases: Nemo)

Ikbkg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate derivative metabolic process GO:1901135 346 0.038
cellular component assembly GO:0022607 360 0.037
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.036
organic acid metabolic process GO:0006082 292 0.035
cellular component biogenesis GO:0044085 368 0.035
Rat
carboxylic acid metabolic process GO:0019752 289 0.035
regulation of phosphate metabolic process GO:0019220 349 0.035
regulation of cellular ketone metabolic process GO:0010565 27 0.034
oxoacid metabolic process GO:0043436 290 0.033
organophosphate metabolic process GO:0019637 370 0.033
protein complex subunit organization GO:0071822 302 0.033
Rat
negative regulation of metabolic process GO:0009892 331 0.033
rna metabolic process GO:0016070 406 0.032
organic substance catabolic process GO:1901575 316 0.032
nucleotide metabolic process GO:0009117 279 0.032
nucleic acid templated transcription GO:0097659 379 0.032
regulation of molecular function GO:0065009 398 0.032
transmembrane transport GO:0055085 412 0.031
protein complex assembly GO:0006461 263 0.031
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
macromolecular complex assembly GO:0065003 273 0.031
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
macromolecule localization GO:0033036 252 0.030
Rat
cellular amino acid metabolic process GO:0006520 107 0.030
regulation of catalytic activity GO:0050790 304 0.030
amine metabolic process GO:0009308 38 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
protein phosphorylation GO:0006468 345 0.029
regulation of transcription dna templated GO:0006355 374 0.029
cellular amine metabolic process GO:0044106 38 0.029
cellular ketone metabolic process GO:0042180 51 0.029
protein complex biogenesis GO:0070271 263 0.028
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.028
rna biosynthetic process GO:0032774 380 0.028
macromolecular complex subunit organization GO:0043933 339 0.028
Rat
regulation of cellular component organization GO:0051128 368 0.028
ion transmembrane transport GO:0034220 365 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
regulation of rna metabolic process GO:0051252 391 0.028
catabolic process GO:0009056 351 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
transcription dna templated GO:0006351 377 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
single organism reproductive process GO:0044702 297 0.027
programmed cell death GO:0012501 392 0.027
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.027
cation transport GO:0006812 382 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
apoptotic process GO:0006915 381 0.026
Rat
positive regulation of cellular component organization GO:0051130 200 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
single organism catabolic process GO:0044712 283 0.025
intracellular signal transduction GO:0035556 314 0.025
regulation of protein metabolic process GO:0051246 289 0.025
regulation of cell differentiation GO:0045595 320 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.025
metal ion transport GO:0030001 289 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
single organism biosynthetic process GO:0044711 342 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
purine containing compound metabolic process GO:0072521 253 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
response to nutrient levels GO:0031667 370 0.024
response to extracellular stimulus GO:0009991 380 0.024
negative regulation of gene expression GO:0010629 199 0.024
reproduction GO:0000003 245 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
reproductive process GO:0022414 372 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
cellular response to oxygen containing compound GO:1901701 386 0.023
positive regulation of transport GO:0051050 245 0.023
homeostatic process GO:0042592 331 0.023
cellular component movement GO:0006928 248 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
secretion GO:0046903 307 0.022
Rat
regulation of signal transduction GO:0009966 318 0.022
cellular catabolic process GO:0044248 295 0.022
protein localization GO:0008104 191 0.022
Rat
positive regulation of molecular function GO:0044093 230 0.022
neuron differentiation GO:0030182 368 0.022
head development GO:0060322 247 0.021
regulation of ion transport GO:0043269 245 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
proteolysis GO:0006508 175 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.021
central nervous system development GO:0007417 311 0.021
response to metal ion GO:0010038 253 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
response to peptide GO:1901652 292 0.020
regulation of cellular localization GO:0060341 263 0.020
cell projection organization GO:0030030 302 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
cellular homeostasis GO:0019725 252 0.020
regulation of cell proliferation GO:0042127 359 0.020
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
organelle organization GO:0006996 266 0.020
Rat
regulation of cell development GO:0060284 263 0.020
regulation of nervous system development GO:0051960 264 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
multi organism reproductive process GO:0044703 262 0.019
cellular lipid metabolic process GO:0044255 208 0.019
anterior posterior pattern specification GO:0009952 1 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
secretion by cell GO:0032940 248 0.019
Rat
purine nucleoside metabolic process GO:0042278 169 0.019
negative regulation of innate immune response GO:0045824 4 0.019
regulation of phosphorylation GO:0042325 248 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
positive regulation of cell communication GO:0010647 271 0.019
regulation of hormone levels GO:0010817 187 0.019
ion homeostasis GO:0050801 212 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.018
neuron projection development GO:0031175 273 0.018
brain development GO:0007420 247 0.018
response to inorganic substance GO:0010035 377 0.018
nucleoside metabolic process GO:0009116 179 0.018
heterocycle catabolic process GO:0046700 167 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
positive regulation of developmental process GO:0051094 283 0.018
cell cell signaling GO:0007267 335 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
neuron development GO:0048666 286 0.018
response to oxygen levels GO:0070482 265 0.018
regulation of apoptotic process GO:0042981 335 0.018
Rat
intracellular transport GO:0046907 185 0.018
nucleoside triphosphate metabolic process GO:0009141 144 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
positive regulation of cell development GO:0010720 176 0.018
regulation of neurogenesis GO:0050767 247 0.018
multicellular organism reproduction GO:0032504 233 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
muscle system process GO:0003012 115 0.017
aromatic compound catabolic process GO:0019439 168 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
chemical homeostasis GO:0048878 292 0.017
locomotion GO:0040011 237 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
negative regulation of cell death GO:0060548 229 0.017
Rat
regulation of intracellular signal transduction GO:1902531 218 0.017
regulation of cell projection organization GO:0031344 175 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
lipid metabolic process GO:0006629 283 0.017
positive regulation of nervous system development GO:0051962 178 0.017
single organism intracellular transport GO:1902582 166 0.017
aging GO:0007568 241 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
single organism cellular localization GO:1902580 102 0.017
divalent inorganic cation transport GO:0072511 134 0.016
vesicle mediated transport GO:0016192 181 0.016
response to acid chemical GO:0001101 222 0.016
regulation of catabolic process GO:0009894 113 0.016
cellular response to stress GO:0033554 269 0.016
cell migration GO:0016477 197 0.016
positive regulation of signaling GO:0023056 270 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.016
regulation of protein modification process GO:0031399 194 0.016
ras protein signal transduction GO:0007265 29 0.016
regulation of programmed cell death GO:0043067 341 0.016
Rat
cation transmembrane transport GO:0098655 263 0.016
regulation of hydrolase activity GO:0051336 143 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
Rat
cellular response to hormone stimulus GO:0032870 247 0.016
purine nucleoside triphosphate catabolic process GO:0009146 122 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
regulation of secretion by cell GO:1903530 208 0.016
response to decreased oxygen levels GO:0036293 237 0.016
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
response to hypoxia GO:0001666 231 0.016
cellular protein localization GO:0034613 122 0.016
response to nutrient GO:0007584 248 0.016
negative regulation of transport GO:0051051 136 0.015
organophosphate catabolic process GO:0046434 148 0.015
positive regulation of nucleotide metabolic process GO:0045981 91 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
regulation of neuron differentiation GO:0045664 208 0.015
regulation of secretion GO:0051046 224 0.015
cation homeostasis GO:0055080 195 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
negative regulation of cell communication GO:0010648 158 0.015
purine containing compound catabolic process GO:0072523 138 0.015
carbohydrate metabolic process GO:0005975 130 0.015
divalent metal ion transport GO:0070838 132 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
Rat
synaptic transmission GO:0007268 235 0.015
cellular chemical homeostasis GO:0055082 247 0.015
nucleoside catabolic process GO:0009164 126 0.015
tissue development GO:0009888 252 0.015
axis specification GO:0009798 4 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
cell motility GO:0048870 202 0.014
metal ion homeostasis GO:0055065 186 0.014
positive regulation of gene expression GO:0010628 244 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
calcium ion transport GO:0006816 131 0.014
cellular response to lipid GO:0071396 201 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.014
response to biotic stimulus GO:0009607 226 0.014
membrane organization GO:0061024 94 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
Rat
nucleoside triphosphate catabolic process GO:0009143 123 0.014
regulation of cellular component movement GO:0051270 150 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
negative regulation of molecular function GO:0044092 133 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
response to growth factor GO:0070848 189 0.014
lipid storage GO:0019915 1 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
response to glucocorticoid GO:0051384 223 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
defense response GO:0006952 194 0.014
nucleotide catabolic process GO:0009166 139 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
cellular macromolecule localization GO:0070727 122 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
response to monosaccharide GO:0034284 159 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
single organism organelle organization GO:1902589 180 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
regulation of metal ion transport GO:0010959 118 0.014
purine nucleoside catabolic process GO:0006152 124 0.013
heart morphogenesis GO:0003007 3 0.013
response to oxidative stress GO:0006979 186 0.013
actin filament based process GO:0030029 86 0.013
sexual reproduction GO:0019953 148 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
cellular cation homeostasis GO:0030003 180 0.013
protein oligomerization GO:0051259 191 0.013
Rat
regeneration GO:0031099 163 0.013
response to carbohydrate GO:0009743 183 0.013
developmental process involved in reproduction GO:0003006 159 0.013
regulation of membrane potential GO:0042391 110 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
response to corticosteroid GO:0031960 235 0.013
circulatory system process GO:0003013 183 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
oxidation reduction process GO:0055114 304 0.013
positive regulation of protein modification process GO:0031401 142 0.013
response to wounding GO:0009611 254 0.013
Rat
blood circulation GO:0008015 183 0.013
response to peptide hormone GO:0043434 278 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
positive regulation of signal transduction GO:0009967 175 0.013
palate development GO:0060021 2 0.013
nitrogen compound transport GO:0071705 229 0.013
regulation of neuron projection development GO:0010975 161 0.013
response to ethanol GO:0045471 162 0.013
response to cytokine GO:0034097 215 0.013
gland development GO:0048732 155 0.013
embryonic pattern specification GO:0009880 1 0.013
maintenance of location GO:0051235 17 0.013
gamete generation GO:0007276 124 0.013
response to bacterium GO:0009617 200 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
response to estrogen GO:0043627 232 0.013
positive regulation of neuron differentiation GO:0045666 126 0.012
localization of cell GO:0051674 202 0.012
negative regulation of signaling GO:0023057 157 0.012
regulation of blood circulation GO:1903522 110 0.012
response to ketone GO:1901654 182 0.012
positive regulation of nucleoside metabolic process GO:0045979 55 0.012
positive regulation of cell death GO:0010942 184 0.012
response to glucose GO:0009749 136 0.012
cytoplasmic transport GO:0016482 115 0.012
peptidyl amino acid modification GO:0018193 126 0.012
growth GO:0040007 165 0.012
single organism membrane organization GO:0044802 74 0.012
chromosome segregation GO:0007059 2 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
multi multicellular organism process GO:0044706 138 0.012
spermatogenesis GO:0007283 99 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
macromolecule catabolic process GO:0009057 58 0.012
response to external biotic stimulus GO:0043207 221 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
actin filament based movement GO:0030048 16 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
regulation of neuron death GO:1901214 115 0.012
Rat
atp catabolic process GO:0006200 54 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
cellular ion homeostasis GO:0006873 184 0.012
rhythmic process GO:0048511 156 0.012
behavior GO:0007610 205 0.012
gastrulation GO:0007369 2 0.012
positive regulation of ion transport GO:0043270 94 0.011
protein transport GO:0015031 132 0.011
Rat
anatomical structure morphogenesis GO:0009653 298 0.011
signal release GO:0023061 145 0.011
neurological system process GO:0050877 219 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
lipid biosynthetic process GO:0008610 128 0.011
immune system process GO:0002376 204 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
eye morphogenesis GO:0048592 4 0.011
positive regulation of catabolic process GO:0009896 78 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
regulation of transmembrane transport GO:0034762 122 0.011
calcium ion homeostasis GO:0055074 162 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
regulation of response to stress GO:0080134 126 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
dna metabolic process GO:0006259 96 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
response to radiation GO:0009314 137 0.011
response to estradiol GO:0032355 164 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
response to lipopolysaccharide GO:0032496 191 0.011
regulation of anatomical structure size GO:0090066 135 0.011
cellular response to external stimulus GO:0071496 118 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
response to organophosphorus GO:0046683 102 0.011
regulation of cell migration GO:0030334 128 0.011
response to vitamin GO:0033273 131 0.011
peptide transport GO:0015833 97 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
reproductive structure development GO:0048608 128 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
response to toxic substance GO:0009636 133 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.010
establishment of protein localization GO:0045184 141 0.010
Rat
reactive oxygen species biosynthetic process GO:1903409 8 0.010
response to purine containing compound GO:0014074 126 0.010
anion transport GO:0006820 178 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
peptide secretion GO:0002790 86 0.010
neuron death GO:0070997 127 0.010
Rat
regulation of mapk cascade GO:0043408 116 0.010
cell adhesion GO:0007155 110 0.010
muscle contraction GO:0006936 88 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
response to hexose GO:0009746 144 0.010
regulation of synaptic transmission GO:0050804 141 0.010
regulation of transferase activity GO:0051338 123 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
regulation of calcium ion transport GO:0051924 77 0.010
positive regulation of nucleotide catabolic process GO:0030813 53 0.010
atp metabolic process GO:0046034 72 0.010
t cell tolerance induction GO:0002517 3 0.010
response to other organism GO:0051707 220 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
ncrna processing GO:0034470 3 0.010
bmp signaling pathway GO:0030509 4 0.010

Ikbkg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.014
sensory system disease DOID:0050155 0 0.013
central nervous system disease DOID:331 0 0.011