Rattus norvegicus

84 known processes

Rxrb

retinoid X receptor beta

(Aliases: RXR-beta)

Rxrb biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 252 0.323
regulation of rna biosynthetic process GO:2001141 381 0.245
regulation of nucleic acid templated transcription GO:1903506 380 0.238
transcription dna templated GO:0006351 377 0.186
positive regulation of signal transduction GO:0009967 175 0.158
Rat
regulation of transcription dna templated GO:0006355 374 0.156
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.146
Zebrafish Rat Worm
regulation of signal transduction GO:0009966 318 0.137
regulation of cellular component organization GO:0051128 368 0.136
Rat
reproductive process GO:0022414 372 0.135
Mouse Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.131
regulation of phosphorus metabolic process GO:0051174 349 0.127
Rat
regulation of rna metabolic process GO:0051252 391 0.119
multicellular organism reproduction GO:0032504 233 0.116
Mouse
multi multicellular organism process GO:0044706 138 0.116
Mouse Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.110
Zebrafish Rat Worm
negative regulation of transcription dna templated GO:0045892 116 0.110
Zebrafish Rat Worm
intracellular signal transduction GO:0035556 314 0.110
Rat
positive regulation of cell communication GO:0010647 271 0.106
Rat
cellular component assembly GO:0022607 360 0.098
Rat
multicellular organism growth GO:0035264 1 0.098
vesicle mediated transport GO:0016192 181 0.098
rna biosynthetic process GO:0032774 380 0.098
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.093
Zebrafish Rat Worm
neuron development GO:0048666 286 0.089
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.085
Human Mouse Rat
negative regulation of gene expression GO:0010629 199 0.082
Zebrafish Rat Worm
rna metabolic process GO:0016070 406 0.081
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.081
Human Mouse Rat
positive regulation of multicellular organismal process GO:0051240 387 0.078
negative regulation of rna metabolic process GO:0051253 123 0.077
Zebrafish Rat Worm
homeostatic process GO:0042592 331 0.075
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.075
Zebrafish Rat Worm
nucleic acid templated transcription GO:0097659 379 0.075
positive regulation of response to stimulus GO:0048584 285 0.073
Rat
protein phosphorylation GO:0006468 345 0.073
Rat
protein complex subunit organization GO:0071822 302 0.072
organelle organization GO:0006996 266 0.071
negative regulation of metabolic process GO:0009892 331 0.070
Zebrafish Rat Worm
single organism reproductive process GO:0044702 297 0.068
Mouse Rat
negative regulation of cell death GO:0060548 229 0.068
oxoacid metabolic process GO:0043436 290 0.067
Rat
reproductive structure development GO:0048608 128 0.067
Mouse Rat
regulation of cellular localization GO:0060341 263 0.062
Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.062
Rat Worm
behavior GO:0007610 205 0.059
positive regulation of biosynthetic process GO:0009891 319 0.057
Human Mouse Rat
multi organism reproductive process GO:0044703 262 0.057
Mouse Rat
neuron projection development GO:0031175 273 0.057
Rat
response to monosaccharide GO:0034284 159 0.057
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.056
Human Mouse Rat
immune response GO:0006955 104 0.055
immune system process GO:0002376 204 0.054
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.054
Human Mouse Rat
negative regulation of cellular metabolic process GO:0031324 281 0.053
Zebrafish Rat Worm
positive regulation of rna biosynthetic process GO:1902680 197 0.053
Human Mouse Rat
protein complex assembly GO:0006461 263 0.052
response to carbohydrate GO:0009743 183 0.051
Rat
regulation of intracellular signal transduction GO:1902531 218 0.051
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.051
Zebrafish Rat Worm
cellular ketone metabolic process GO:0042180 51 0.050
Rat
growth GO:0040007 165 0.050
Mouse
positive regulation of developmental process GO:0051094 283 0.050
response to hexose GO:0009746 144 0.050
Rat
carboxylic acid metabolic process GO:0019752 289 0.050
Rat
protein complex biogenesis GO:0070271 263 0.050
regulation of hormone secretion GO:0046883 106 0.049
regulation of cellular ketone metabolic process GO:0010565 27 0.049
Rat
central nervous system development GO:0007417 311 0.048
developmental process involved in reproduction GO:0003006 159 0.048
Mouse Rat
cellular component morphogenesis GO:0032989 155 0.048
regulation of hormone levels GO:0010817 187 0.047
single organism behavior GO:0044708 130 0.047
neuron differentiation GO:0030182 368 0.047
Rat
regulation of multicellular organismal development GO:2000026 376 0.046
cellular homeostasis GO:0019725 252 0.046
anatomical structure morphogenesis GO:0009653 298 0.045
Rat
organic acid metabolic process GO:0006082 292 0.045
Rat
positive regulation of rna metabolic process GO:0051254 203 0.044
Human Mouse Rat
protein localization GO:0008104 191 0.044
Rat
cardiovascular system development GO:0072358 134 0.044
Mouse Rat
gland development GO:0048732 155 0.044
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.044
Human Mouse Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.044
Human Mouse Rat
regulation of protein modification process GO:0031399 194 0.043
Rat
positive regulation of protein metabolic process GO:0051247 178 0.043
Rat
regulation of catalytic activity GO:0050790 304 0.043
Rat
neuron death GO:0070997 127 0.042
peptide hormone secretion GO:0030072 84 0.040
response to glucose GO:0009749 136 0.040
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.040
Rat
regulation of protein phosphorylation GO:0001932 183 0.040
Rat
amine metabolic process GO:0009308 38 0.039
cellular component biogenesis GO:0044085 368 0.039
Rat
regulation of programmed cell death GO:0043067 341 0.039
Rat
positive regulation of gene expression GO:0010628 244 0.039
Human Mouse Rat
dna metabolic process GO:0006259 96 0.039
cellular lipid metabolic process GO:0044255 208 0.038
Rat
negative regulation of cell communication GO:0010648 158 0.037
Rat
negative regulation of biosynthetic process GO:0009890 168 0.037
Zebrafish Rat Worm
cell morphogenesis involved in differentiation GO:0000904 119 0.036
positive regulation of cellular component organization GO:0051130 200 0.036
response to nutrient levels GO:0031667 370 0.035
Rat
urogenital system development GO:0001655 78 0.035
organic substance catabolic process GO:1901575 316 0.035
cell cell signaling GO:0007267 335 0.034
positive regulation of transcription dna templated GO:0045893 197 0.034
Human Mouse Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.034
Zebrafish Rat Worm
regulation of molecular function GO:0065009 398 0.033
sex differentiation GO:0007548 113 0.033
negative regulation of nucleic acid templated transcription GO:1903507 117 0.033
Zebrafish Rat Worm
regulation of immune system process GO:0002682 123 0.033
organophosphate metabolic process GO:0019637 370 0.033
positive regulation of signaling GO:0023056 270 0.033
Rat
negative regulation of response to stimulus GO:0048585 155 0.032
Rat
response to peptide GO:1901652 292 0.032
Rat
macromolecular complex assembly GO:0065003 273 0.032
regulation of cell differentiation GO:0045595 320 0.031
Rat
catabolic process GO:0009056 351 0.031
bmp signaling pathway GO:0030509 4 0.031
single organism biosynthetic process GO:0044711 342 0.031
Rat
regulation of cell cycle GO:0051726 73 0.030
Rat
brain development GO:0007420 247 0.030
macromolecule localization GO:0033036 252 0.030
Rat Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
Zebrafish Rat Worm
response to metal ion GO:0010038 253 0.030
response to extracellular stimulus GO:0009991 380 0.030
Rat
negative regulation of signaling GO:0023057 157 0.028
Rat
proteolysis GO:0006508 175 0.028
aging GO:0007568 241 0.028
Rat
reproductive system development GO:0061458 128 0.028
Mouse Rat
single organism organelle organization GO:1902589 180 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.028
regulation of phosphorylation GO:0042325 248 0.027
Rat
positive regulation of organelle organization GO:0010638 48 0.027
localization of cell GO:0051674 202 0.027
positive regulation of intracellular signal transduction GO:1902533 138 0.027
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.027
cell type specific apoptotic process GO:0097285 134 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
Rat
cell projection organization GO:0030030 302 0.026
Rat
response to inorganic substance GO:0010035 377 0.026
Rat
microvillus assembly GO:0030033 2 0.026
Rat
cell morphogenesis GO:0000902 142 0.026
axon development GO:0061564 96 0.026
Rat
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.026
positive regulation of map kinase activity GO:0043406 46 0.025
regulation of response to external stimulus GO:0032101 106 0.025
regulation of ion transport GO:0043269 245 0.025
tube development GO:0035295 89 0.025
Rat
regulation of nervous system development GO:0051960 264 0.025
cellular catabolic process GO:0044248 295 0.024
cellular component movement GO:0006928 248 0.024
heterocycle catabolic process GO:0046700 167 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
Mouse
lipid metabolic process GO:0006629 283 0.024
Rat
response to nutrient GO:0007584 248 0.024
Rat
chemical homeostasis GO:0048878 292 0.024
cellular amine metabolic process GO:0044106 38 0.024
cell projection morphogenesis GO:0048858 123 0.023
regulation of apoptotic process GO:0042981 335 0.023
Rat
macromolecular complex subunit organization GO:0043933 339 0.023
regulation of protein metabolic process GO:0051246 289 0.023
Rat
organic cyclic compound catabolic process GO:1901361 175 0.023
response to biotic stimulus GO:0009607 226 0.023
regulation of cytoskeleton organization GO:0051493 49 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.023
Rat
peptide secretion GO:0002790 86 0.022
lipid biosynthetic process GO:0008610 128 0.022
Rat
protein oligomerization GO:0051259 191 0.022
regulation of protein kinase activity GO:0045859 105 0.022
Rat
positive regulation of kinase activity GO:0033674 77 0.022
Rat
head development GO:0060322 247 0.022
regulation of kinase activity GO:0043549 117 0.022
Rat
nucleotide metabolic process GO:0009117 279 0.022
regulation of cell development GO:0060284 263 0.022
Rat
endocytosis GO:0006897 84 0.021
macromolecule catabolic process GO:0009057 58 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
response to ketone GO:1901654 182 0.021
heart morphogenesis GO:0003007 3 0.021
muscle structure development GO:0061061 87 0.020
Mouse Rat
gonad development GO:0008406 104 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
defense response GO:0006952 194 0.020
Rat
exocytosis GO:0006887 60 0.019
positive regulation of mitochondrion organization GO:0010822 4 0.019
anion transport GO:0006820 178 0.019
peptidyl amino acid modification GO:0018193 126 0.019
Rat
response to lipopolysaccharide GO:0032496 191 0.019
organic hydroxy compound metabolic process GO:1901615 115 0.019
action potential GO:0001508 54 0.019
regulation of neuron death GO:1901214 115 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
Rat
positive regulation of cell development GO:0010720 176 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
Rat
reproduction GO:0000003 245 0.018
Mouse
purine ribonucleotide metabolic process GO:0009150 227 0.018
peptide transport GO:0015833 97 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
sensory organ development GO:0007423 74 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
Rat
protein modification by small protein conjugation GO:0032446 31 0.018
single organism intracellular transport GO:1902582 166 0.018
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
regulation of secretion GO:0051046 224 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
Rat
regulation of immune response GO:0050776 55 0.017
protein homooligomerization GO:0051260 91 0.017
cation transport GO:0006812 382 0.017
positive regulation of molecular function GO:0044093 230 0.017
heart development GO:0007507 72 0.017
Mouse Rat
gliogenesis GO:0042063 93 0.017
neuron projection morphogenesis GO:0048812 122 0.017
hormone secretion GO:0046879 115 0.017
sexual reproduction GO:0019953 148 0.017
glial cell differentiation GO:0010001 65 0.017
gastrulation GO:0007369 2 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
Rat
negative regulation of transport GO:0051051 136 0.016
Rat
cellular response to stress GO:0033554 269 0.016
Rat
p38mapk cascade GO:0038066 1 0.016
positive regulation of transferase activity GO:0051347 81 0.016
Rat
transmembrane transport GO:0055085 412 0.016
regulation of growth GO:0040008 105 0.016
protein modification by small protein conjugation or removal GO:0070647 35 0.016
cell cycle GO:0007049 101 0.016
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
Rat
hormone transport GO:0009914 121 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
aromatic compound catabolic process GO:0019439 168 0.016
negative regulation of protein import into nucleus translocation GO:0033159 1 0.016
Rat
cell part morphogenesis GO:0032990 123 0.016
maintenance of location GO:0051235 17 0.016
Worm
cell migration GO:0016477 197 0.015
immune system development GO:0002520 41 0.015
regulation of hydrolase activity GO:0051336 143 0.015
intracellular transport GO:0046907 185 0.015
Rat
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
Rat
response to purine containing compound GO:0014074 126 0.015
Rat
cellular response to oxygen containing compound GO:1901701 386 0.015
Mouse Rat
regulation of transferase activity GO:0051338 123 0.015
Rat
cellular response to nitrogen compound GO:1901699 210 0.015
Rat
insulin secretion GO:0030073 69 0.015
membrane repolarization GO:0086009 1 0.015
negative regulation of programmed cell death GO:0043069 183 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
Rat
anterior posterior pattern specification GO:0009952 1 0.014
response to estrogen GO:0043627 232 0.014
Rat
secretion GO:0046903 307 0.014
regulation of neurogenesis GO:0050767 247 0.014
Rat
eye development GO:0001654 50 0.014
response to acid chemical GO:0001101 222 0.014
Mouse Rat
reactive oxygen species metabolic process GO:0072593 37 0.014
development of primary sexual characteristics GO:0045137 107 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
ovulation cycle GO:0042698 67 0.013
response to bacterium GO:0009617 200 0.013
regulation of cell projection organization GO:0031344 175 0.013
Rat
purine containing compound metabolic process GO:0072521 253 0.013
gamete generation GO:0007276 124 0.013
response to oxidative stress GO:0006979 186 0.013
response to decreased oxygen levels GO:0036293 237 0.013
tissue development GO:0009888 252 0.013
Mouse Rat
negative regulation of protein metabolic process GO:0051248 114 0.013
Rat
protein ubiquitination GO:0016567 28 0.013
response to hypoxia GO:0001666 231 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
Rat
glucose homeostasis GO:0042593 75 0.013
positive regulation of growth GO:0045927 55 0.013
oxidation reduction process GO:0055114 304 0.013
response to external biotic stimulus GO:0043207 221 0.013
organ morphogenesis GO:0009887 75 0.013
positive regulation of cell death GO:0010942 184 0.013
Rat
regulation of organelle organization GO:0033043 80 0.013
chromosome segregation GO:0007059 2 0.013
locomotion GO:0040011 237 0.013
response to camp GO:0051591 91 0.013
Rat
organophosphate catabolic process GO:0046434 148 0.013
amide transport GO:0042886 105 0.012
regulation of system process GO:0044057 208 0.012
calcium mediated signaling using intracellular calcium source GO:0035584 1 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
Rat
lipid storage GO:0019915 1 0.012
Worm
regulation of nucleotide metabolic process GO:0006140 117 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
cellular protein complex assembly GO:0043623 44 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.012
regulation of transcription regulatory region dna binding GO:2000677 4 0.012
cell fate determination GO:0001709 2 0.012
establishment of protein localization GO:0045184 141 0.012
Rat
rhythmic process GO:0048511 156 0.012
single organism catabolic process GO:0044712 283 0.012
response to cytokine GO:0034097 215 0.012
response to other organism GO:0051707 220 0.012
divalent inorganic cation transport GO:0072511 134 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of peptide secretion GO:0002791 82 0.012
positive regulation of ion transport GO:0043270 94 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
neurological system process GO:0050877 219 0.011
positive regulation of nervous system development GO:0051962 178 0.011
glycerolipid metabolic process GO:0046486 67 0.011
dendrite morphogenesis GO:0048813 43 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
cell adhesion GO:0007155 110 0.011
signal release GO:0023061 145 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
apoptotic process GO:0006915 381 0.011
Rat
ribose phosphate metabolic process GO:0019693 235 0.011
male gamete generation GO:0048232 99 0.011
programmed cell death GO:0012501 392 0.011
Rat
carbohydrate metabolic process GO:0005975 130 0.011
Rat
negative regulation of catalytic activity GO:0043086 103 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
regulation of synapse maturation GO:0090128 2 0.011
positive regulation of transport GO:0051050 245 0.011
response to temperature stimulus GO:0009266 94 0.011
renal system development GO:0072001 67 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
positive regulation of secretion GO:0051047 140 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
Rat
positive regulation of synapse maturation GO:0090129 2 0.010
phospholipid metabolic process GO:0006644 61 0.010
regulation of insulin secretion GO:0050796 65 0.010
regulation of bmp signaling pathway GO:0030510 2 0.010
axonogenesis GO:0007409 71 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
secretion by cell GO:0032940 248 0.010
biological adhesion GO:0022610 110 0.010
acid secretion GO:0046717 48 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
regulation of membrane potential GO:0042391 110 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010

Rxrb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.051
charcot marie tooth disease type 2 DOID:0050539 0 0.051
disease of anatomical entity DOID:7 0 0.051
charcot marie tooth disease DOID:10595 0 0.051
nervous system disease DOID:863 0 0.051
neuropathy DOID:870 0 0.051
long qt syndrome DOID:2843 0 0.013