Rattus norvegicus

0 known processes

Porcn

porcupine homolog (Drosophila)

(Aliases: RGD1564947)

Porcn biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to oxygen containing compound GO:1901701 386 0.105
transcription dna templated GO:0006351 377 0.097
nucleic acid templated transcription GO:0097659 379 0.080
neuron differentiation GO:0030182 368 0.072
intracellular signal transduction GO:0035556 314 0.069
regulation of nucleic acid templated transcription GO:1903506 380 0.065
negative regulation of metabolic process GO:0009892 331 0.063
negative regulation of cellular metabolic process GO:0031324 281 0.060
cellular response to organonitrogen compound GO:0071417 197 0.059
ribonucleotide metabolic process GO:0009259 231 0.057
cell projection organization GO:0030030 302 0.055
positive regulation of cellular biosynthetic process GO:0031328 295 0.054
positive regulation of biosynthetic process GO:0009891 319 0.053
regulation of rna metabolic process GO:0051252 391 0.052
neuron development GO:0048666 286 0.051
rna metabolic process GO:0016070 406 0.050
homeostatic process GO:0042592 331 0.047
cellular chemical homeostasis GO:0055082 247 0.047
apoptotic process GO:0006915 381 0.047
regulation of cellular component organization GO:0051128 368 0.046
cellular response to stress GO:0033554 269 0.045
rna biosynthetic process GO:0032774 380 0.045
positive regulation of cell communication GO:0010647 271 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.044
positive regulation of signaling GO:0023056 270 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.039
organophosphate metabolic process GO:0019637 370 0.039
negative regulation of biosynthetic process GO:0009890 168 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
regulation of rna biosynthetic process GO:2001141 381 0.038
signal release GO:0023061 145 0.037
central nervous system development GO:0007417 311 0.037
reproductive process GO:0022414 372 0.036
positive regulation of response to stimulus GO:0048584 285 0.036
anatomical structure morphogenesis GO:0009653 298 0.036
neuron projection morphogenesis GO:0048812 122 0.035
hormone transport GO:0009914 121 0.035
multicellular organismal reproductive process GO:0048609 233 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.033
regulation of phosphorylation GO:0042325 248 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
secretion GO:0046903 307 0.033
cellular response to nitrogen compound GO:1901699 210 0.032
regulation of molecular function GO:0065009 398 0.032
cellular homeostasis GO:0019725 252 0.032
neuron projection development GO:0031175 273 0.031
organic substance catabolic process GO:1901575 316 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
cell cell signaling GO:0007267 335 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.031
aging GO:0007568 241 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
regulation of transcription dna templated GO:0006355 374 0.030
multi organism reproductive process GO:0044703 262 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.030
programmed cell death GO:0012501 392 0.030
cation transport GO:0006812 382 0.029
cellular component movement GO:0006928 248 0.029
transmembrane transport GO:0055085 412 0.029
positive regulation of cell death GO:0010942 184 0.029
metal ion homeostasis GO:0055065 186 0.029
regulation of catalytic activity GO:0050790 304 0.029
nucleotide metabolic process GO:0009117 279 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
single organism reproductive process GO:0044702 297 0.028
non canonical wnt signaling pathway GO:0035567 3 0.028
cellular component biogenesis GO:0044085 368 0.028
protein phosphorylation GO:0006468 345 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
oxoacid metabolic process GO:0043436 290 0.027
ion homeostasis GO:0050801 212 0.027
regulation of intracellular signal transduction GO:1902531 218 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
organelle organization GO:0006996 266 0.026
response to nutrient levels GO:0031667 370 0.026
positive regulation of gene expression GO:0010628 244 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
chemical homeostasis GO:0048878 292 0.026
regulation of secretion GO:0051046 224 0.026
forebrain development GO:0030900 98 0.026
metal ion transport GO:0030001 289 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
regulation of membrane potential GO:0042391 110 0.025
ion transmembrane transport GO:0034220 365 0.025
cellular component assembly GO:0022607 360 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
protein complex biogenesis GO:0070271 263 0.025
locomotion GO:0040011 237 0.025
cellular cation homeostasis GO:0030003 180 0.025
cellular response to peptide GO:1901653 133 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
nitrogen compound transport GO:0071705 229 0.025
regulation of ion transport GO:0043269 245 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.024
positive regulation of intracellular signal transduction GO:1902533 138 0.024
regulation of cell proliferation GO:0042127 359 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
macromolecular complex subunit organization GO:0043933 339 0.023
nucleoside metabolic process GO:0009116 179 0.023
organic acid metabolic process GO:0006082 292 0.023
response to extracellular stimulus GO:0009991 380 0.023
regulation of apoptotic process GO:0042981 335 0.023
regulation of programmed cell death GO:0043067 341 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.023
positive regulation of signal transduction GO:0009967 175 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
regulation of hormone levels GO:0010817 187 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
synaptic transmission GO:0007268 235 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
positive regulation of secretion GO:0051047 140 0.021
cellular amine metabolic process GO:0044106 38 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.020
gland development GO:0048732 155 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.020
regulation of system process GO:0044057 208 0.020
response to carbohydrate GO:0009743 183 0.020
protein complex assembly GO:0006461 263 0.020
hormone secretion GO:0046879 115 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
brain development GO:0007420 247 0.020
protein complex subunit organization GO:0071822 302 0.020
localization of cell GO:0051674 202 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
response to cytokine GO:0034097 215 0.020
purine containing compound metabolic process GO:0072521 253 0.020
protein oligomerization GO:0051259 191 0.020
regulation of protein modification process GO:0031399 194 0.019
cell morphogenesis involved in differentiation GO:0000904 119 0.019
amine metabolic process GO:0009308 38 0.019
head development GO:0060322 247 0.019
cellular response to lipid GO:0071396 201 0.019
cellular catabolic process GO:0044248 295 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
cellular response to hormone stimulus GO:0032870 247 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
positive regulation of developmental process GO:0051094 283 0.018
proteolysis GO:0006508 175 0.018
catabolic process GO:0009056 351 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
response to estradiol GO:0032355 164 0.018
regulation of response to stress GO:0080134 126 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
regulation of multicellular organismal development GO:2000026 376 0.017
multi multicellular organism process GO:0044706 138 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
regulation of nervous system development GO:0051960 264 0.017
ribonucleotide biosynthetic process GO:0009260 85 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
negative regulation of gene expression GO:0010629 199 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
positive regulation of protein modification process GO:0031401 142 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
multicellular organism reproduction GO:0032504 233 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
secretion by cell GO:0032940 248 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
organ morphogenesis GO:0009887 75 0.017
regulation of signal transduction GO:0009966 318 0.016
exocytosis GO:0006887 60 0.016
regulation of cell differentiation GO:0045595 320 0.016
response to inorganic substance GO:0010035 377 0.016
regulation of cell development GO:0060284 263 0.016
regulation of neuron differentiation GO:0045664 208 0.016
regulation of cell projection organization GO:0031344 175 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
reproduction GO:0000003 245 0.016
calcium ion homeostasis GO:0055074 162 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
membrane organization GO:0061024 94 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
negative regulation of transport GO:0051051 136 0.015
positive regulation of molecular function GO:0044093 230 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of hormone secretion GO:0046883 106 0.015
negative regulation of cell communication GO:0010648 158 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
cell morphogenesis GO:0000902 142 0.015
cellular ketone metabolic process GO:0042180 51 0.015
response to corticosteroid GO:0031960 235 0.015
cell type specific apoptotic process GO:0097285 134 0.015
amide transport GO:0042886 105 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
response to metal ion GO:0010038 253 0.015
cell projection morphogenesis GO:0048858 123 0.015
response to wounding GO:0009611 254 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
carbohydrate homeostasis GO:0033500 75 0.015
cation homeostasis GO:0055080 195 0.015
cellular response to hexose stimulus GO:0071331 65 0.014
response to ketone GO:1901654 182 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
regulation of cellular component movement GO:0051270 150 0.014
regulation of protein metabolic process GO:0051246 289 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
response to glucose GO:0009749 136 0.014
peptide hormone secretion GO:0030072 84 0.014
sexual reproduction GO:0019953 148 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
insulin secretion GO:0030073 69 0.014
peptide transport GO:0015833 97 0.014
developmental process involved in reproduction GO:0003006 159 0.014
regulation of neurogenesis GO:0050767 247 0.014
neuron death GO:0070997 127 0.014
response to ethanol GO:0045471 162 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
single organism catabolic process GO:0044712 283 0.014
regulation of neurotransmitter levels GO:0001505 42 0.014
response to oxygen levels GO:0070482 265 0.014
heart morphogenesis GO:0003007 3 0.014
response to decreased oxygen levels GO:0036293 237 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.013
response to nutrient GO:0007584 248 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
response to peptide GO:1901652 292 0.013
response to peptide hormone GO:0043434 278 0.013
macromolecule localization GO:0033036 252 0.013
response to hypoxia GO:0001666 231 0.013
lipid metabolic process GO:0006629 283 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
intracellular transport GO:0046907 185 0.013
response to acid chemical GO:0001101 222 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
cyclic nucleotide biosynthetic process GO:0009190 63 0.013
negative regulation of programmed cell death GO:0043069 183 0.012
regulation of synaptic transmission GO:0050804 141 0.012
response to glucocorticoid GO:0051384 223 0.012
cell migration GO:0016477 197 0.012
carboxylic acid metabolic process GO:0019752 289 0.012
male mating behavior GO:0060179 3 0.012
appendage morphogenesis GO:0035107 4 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
regulation of cell cycle GO:0051726 73 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
response to monosaccharide GO:0034284 159 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
macromolecular complex assembly GO:0065003 273 0.012
regulation of locomotion GO:0040012 148 0.012
regulation of secretion by cell GO:1903530 208 0.012
peptide secretion GO:0002790 86 0.012
development of primary sexual characteristics GO:0045137 107 0.012
regulation of neuron projection development GO:0010975 161 0.012
telencephalon development GO:0021537 62 0.012
regulation of cell motility GO:2000145 131 0.012
regulation of cell migration GO:0030334 128 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
cell adhesion GO:0007155 110 0.012
single organism biosynthetic process GO:0044711 342 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
response to external biotic stimulus GO:0043207 221 0.011
positive regulation of transport GO:0051050 245 0.011
limbic system development GO:0021761 38 0.011
cell motility GO:0048870 202 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
cell cycle GO:0007049 101 0.011
jak stat cascade GO:0007259 26 0.011
regulation of cellular response to stress GO:0080135 49 0.011
neurological system process GO:0050877 219 0.011
calcium ion transport GO:0006816 131 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
glucose homeostasis GO:0042593 75 0.011
protein localization GO:0008104 191 0.011
peptidyl amino acid modification GO:0018193 126 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
anterior posterior pattern specification GO:0009952 1 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
gamete generation GO:0007276 124 0.011
growth GO:0040007 165 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
cellular ion homeostasis GO:0006873 184 0.011
ras protein signal transduction GO:0007265 29 0.011
neuromuscular process GO:0050905 2 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
heterocycle catabolic process GO:0046700 167 0.011
negative regulation of molecular function GO:0044092 133 0.011
axis specification GO:0009798 4 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
single organism membrane organization GO:0044802 74 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.010
aromatic compound catabolic process GO:0019439 168 0.010
regulation of transferase activity GO:0051338 123 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
positive regulation of protein metabolic process GO:0051247 178 0.010
regulation of neuronal synaptic plasticity GO:0048168 31 0.010
cellular response to carbohydrate stimulus GO:0071322 72 0.010
cellular protein localization GO:0034613 122 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
dna metabolic process GO:0006259 96 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
cell cycle process GO:0022402 57 0.010
response to toxic substance GO:0009636 133 0.010
regulation of growth GO:0040008 105 0.010
divalent metal ion transport GO:0070838 132 0.010
muscle structure development GO:0061061 87 0.010
liver development GO:0001889 90 0.010
motor neuron axon guidance GO:0008045 1 0.010
positive regulation of neuron projection development GO:0010976 99 0.010

Porcn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.010