Rattus norvegicus

7 known processes

Tpp1

tripeptidyl peptidase I

(Aliases: Cln2)

Tpp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.210
oxoacid metabolic process GO:0043436 290 0.132
cellular lipid metabolic process GO:0044255 208 0.068
carboxylic acid metabolic process GO:0019752 289 0.065
reproductive process GO:0022414 372 0.062
response to extracellular stimulus GO:0009991 380 0.060
cellular catabolic process GO:0044248 295 0.054
amine metabolic process GO:0009308 38 0.053
positive regulation of nervous system development GO:0051962 178 0.045
response to nutrient levels GO:0031667 370 0.043
cellular response to hormone stimulus GO:0032870 247 0.042
response to peptide hormone GO:0043434 278 0.042
secretion GO:0046903 307 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.039
lipid metabolic process GO:0006629 283 0.038
cellular amino acid metabolic process GO:0006520 107 0.038
cellular amine metabolic process GO:0044106 38 0.036
reproductive structure development GO:0048608 128 0.035
cellular response to nitrogen compound GO:1901699 210 0.035
neurological system process GO:0050877 219 0.035
response to estrogen GO:0043627 232 0.034
neuron projection development GO:0031175 273 0.034
regulation of neuron differentiation GO:0045664 208 0.033
regulation of neuron projection development GO:0010975 161 0.032
head development GO:0060322 247 0.031
regulation of multicellular organismal development GO:2000026 376 0.031
regulation of cell projection organization GO:0031344 175 0.030
regulation of programmed cell death GO:0043067 341 0.030
response to ketone GO:1901654 182 0.030
cellular response to endogenous stimulus GO:0071495 377 0.029
male mating behavior GO:0060179 3 0.029
organic anion transport GO:0015711 132 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
negative regulation of cell death GO:0060548 229 0.029
programmed cell death GO:0012501 392 0.028
regulation of neurogenesis GO:0050767 247 0.028
circulatory system process GO:0003013 183 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
cellular ketone metabolic process GO:0042180 51 0.027
regulation of cell differentiation GO:0045595 320 0.027
response to peptide GO:1901652 292 0.027
regulation of cellular component organization GO:0051128 368 0.026
response to nutrient GO:0007584 248 0.026
regulation of dendrite development GO:0050773 59 0.026
synaptic transmission GO:0007268 235 0.026
central nervous system development GO:0007417 311 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
blood circulation GO:0008015 183 0.025
response to glucocorticoid GO:0051384 223 0.025
cell projection organization GO:0030030 302 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
response to decreased oxygen levels GO:0036293 237 0.025
cellular response to peptide GO:1901653 133 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
response to ethanol GO:0045471 162 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
regeneration GO:0031099 163 0.024
neuron differentiation GO:0030182 368 0.023
regulation of hormone levels GO:0010817 187 0.023
regulation of cell development GO:0060284 263 0.023
single organism reproductive process GO:0044702 297 0.023
gland development GO:0048732 155 0.022
monocarboxylic acid metabolic process GO:0032787 152 0.022
response to camp GO:0051591 91 0.021
positive regulation of neuron differentiation GO:0045666 126 0.021
response to carbohydrate GO:0009743 183 0.021
neuron development GO:0048666 286 0.021
catabolic process GO:0009056 351 0.021
regulation of protein metabolic process GO:0051246 289 0.020
regulation of apoptotic process GO:0042981 335 0.020
positive regulation of neuron projection development GO:0010976 99 0.020
reproduction GO:0000003 245 0.020
regulation of molecular function GO:0065009 398 0.020
chemical homeostasis GO:0048878 292 0.020
multicellular organism reproduction GO:0032504 233 0.020
rhythmic process GO:0048511 156 0.020
regulation of system process GO:0044057 208 0.019
carbohydrate metabolic process GO:0005975 130 0.019
hormone metabolic process GO:0042445 69 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
glycerolipid metabolic process GO:0046486 67 0.019
neuronal action potential GO:0019228 35 0.019
homeostatic process GO:0042592 331 0.019
cell cell signaling GO:0007267 335 0.018
cell projection morphogenesis GO:0048858 123 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
nitrogen compound transport GO:0071705 229 0.017
protein phosphorylation GO:0006468 345 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
transmembrane transport GO:0055085 412 0.017
peptidyl amino acid modification GO:0018193 126 0.017
cellular carbohydrate metabolic process GO:0044262 72 0.017
response to acid chemical GO:0001101 222 0.017
negative regulation of apoptotic process GO:0043066 181 0.016
regulation of nervous system development GO:0051960 264 0.016
apoptotic process GO:0006915 381 0.016
cation transmembrane transport GO:0098655 263 0.016
regulation of body fluid levels GO:0050878 90 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
learning or memory GO:0007611 90 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
response to oxygen levels GO:0070482 265 0.016
synaptic vesicle endocytosis GO:0048488 4 0.016
glial cell differentiation GO:0010001 65 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
response to retinoic acid GO:0032526 63 0.015
cellular response to lipid GO:0071396 201 0.015
salivary gland development GO:0007431 3 0.015
single organism biosynthetic process GO:0044711 342 0.014
response to wounding GO:0009611 254 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
defense response GO:0006952 194 0.014
dendrite development GO:0016358 72 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
positive regulation of cell development GO:0010720 176 0.014
polysaccharide metabolic process GO:0005976 25 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
response to insulin GO:0032868 133 0.014
lipid biosynthetic process GO:0008610 128 0.014
neuron projection morphogenesis GO:0048812 122 0.013
multicellular organism growth GO:0035264 1 0.013
proteolysis GO:0006508 175 0.013
response to hypoxia GO:0001666 231 0.013
cellular polysaccharide metabolic process GO:0044264 23 0.013
intracellular signal transduction GO:0035556 314 0.013
cellular glucan metabolic process GO:0006073 23 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
regulation of membrane potential GO:0042391 110 0.013
cellular homeostasis GO:0019725 252 0.013
carboxylic acid transport GO:0046942 115 0.013
reproductive system development GO:0061458 128 0.013
transmission of nerve impulse GO:0019226 42 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
response to estradiol GO:0032355 164 0.013
aging GO:0007568 241 0.012
positive regulation of gene expression GO:0010628 244 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
response to hexose GO:0009746 144 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
cellular hormone metabolic process GO:0034754 49 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
cellular response to stress GO:0033554 269 0.012
steroid metabolic process GO:0008202 73 0.012
multi organism reproductive process GO:0044703 262 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
cation homeostasis GO:0055080 195 0.012
energy derivation by oxidation of organic compounds GO:0015980 46 0.012
behavior GO:0007610 205 0.011
response to glucose GO:0009749 136 0.011
molting cycle GO:0042303 3 0.011
lipid storage GO:0019915 1 0.011
response to vitamin GO:0033273 131 0.011
response to inorganic substance GO:0010035 377 0.011
metal ion homeostasis GO:0055065 186 0.011
cell part morphogenesis GO:0032990 123 0.011
anion transport GO:0006820 178 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
oxidation reduction process GO:0055114 304 0.011
keratan sulfate metabolic process GO:0042339 1 0.011
organophosphate metabolic process GO:0019637 370 0.011
jak stat cascade GO:0007259 26 0.011
action potential GO:0001508 54 0.011
cellular chemical homeostasis GO:0055082 247 0.011
glycogen metabolic process GO:0005977 23 0.011
gliogenesis GO:0042063 93 0.011
cell migration GO:0016477 197 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
hair cycle GO:0042633 3 0.011
organic acid transport GO:0015849 116 0.010
developmental process involved in reproduction GO:0003006 159 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.010
response to monosaccharide GO:0034284 159 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
lipid localization GO:0010876 62 0.010
response to corticosteroid GO:0031960 235 0.010
regulation of catalytic activity GO:0050790 304 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
positive regulation of blood circulation GO:1903524 65 0.010
response to bacterium GO:0009617 200 0.010

Tpp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.380
inherited metabolic disorder DOID:655 0 0.380
lipid storage disease DOID:9455 0 0.221
lysosomal storage disease DOID:3211 0 0.221
cerebral degeneration DOID:1443 0 0.028
central nervous system disease DOID:331 0 0.028
brain disease DOID:936 0 0.028
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028