Rattus norvegicus

7 known processes

Tpp2

tripeptidyl peptidase II

(Aliases: TPP-2)

Tpp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of signal transduction GO:0009966 318 0.195
intracellular signal transduction GO:0035556 314 0.168
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.106
response to biotic stimulus GO:0009607 226 0.098
regulation of phosphate metabolic process GO:0019220 349 0.097
regulation of phosphorylation GO:0042325 248 0.081
inorganic cation transmembrane transport GO:0098662 202 0.072
response to extracellular stimulus GO:0009991 380 0.065
protein phosphorylation GO:0006468 345 0.061
regulation of cellular component organization GO:0051128 368 0.060
regulation of intracellular signal transduction GO:1902531 218 0.060
regulation of protein modification process GO:0031399 194 0.059
regulation of programmed cell death GO:0043067 341 0.057
regulation of protein phosphorylation GO:0001932 183 0.056
negative regulation of cellular metabolic process GO:0031324 281 0.056
muscle system process GO:0003012 115 0.056
regulation of catalytic activity GO:0050790 304 0.053
negative regulation of metabolic process GO:0009892 331 0.053
regulation of molecular function GO:0065009 398 0.053
response to inorganic substance GO:0010035 377 0.052
response to growth factor GO:0070848 189 0.052
head development GO:0060322 247 0.051
response to peptide GO:1901652 292 0.051
response to nutrient levels GO:0031667 370 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.048
positive regulation of signaling GO:0023056 270 0.048
regulation of rna biosynthetic process GO:2001141 381 0.047
anatomical structure morphogenesis GO:0009653 298 0.047
regulation of cellular localization GO:0060341 263 0.046
multicellular organismal reproductive process GO:0048609 233 0.046
regulation of multicellular organismal development GO:2000026 376 0.046
single organism intracellular transport GO:1902582 166 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
negative regulation of response to stimulus GO:0048585 155 0.043
rna biosynthetic process GO:0032774 380 0.042
muscle contraction GO:0006936 88 0.042
regulation of protein metabolic process GO:0051246 289 0.042
response to metal ion GO:0010038 253 0.041
nucleic acid templated transcription GO:0097659 379 0.040
cellular response to endogenous stimulus GO:0071495 377 0.040
positive regulation of phosphorus metabolic process GO:0010562 262 0.040
response to other organism GO:0051707 220 0.039
regulation of phosphorus metabolic process GO:0051174 349 0.039
cellular response to growth factor stimulus GO:0071363 162 0.039
cellular homeostasis GO:0019725 252 0.038
ras protein signal transduction GO:0007265 29 0.038
response to acid chemical GO:0001101 222 0.038
positive regulation of response to stimulus GO:0048584 285 0.037
positive regulation of protein transport GO:0051222 41 0.036
cellular ion homeostasis GO:0006873 184 0.035
organelle organization GO:0006996 266 0.035
cellular response to oxygen containing compound GO:1901701 386 0.034
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.034
neuron projection development GO:0031175 273 0.034
positive regulation of developmental process GO:0051094 283 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
intracellular transport GO:0046907 185 0.033
response to bacterium GO:0009617 200 0.033
response to toxic substance GO:0009636 133 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
regulation of cell differentiation GO:0045595 320 0.031
reproduction GO:0000003 245 0.031
central nervous system development GO:0007417 311 0.030
transmembrane transport GO:0055085 412 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.029
establishment of protein localization GO:0045184 141 0.029
negative regulation of cell communication GO:0010648 158 0.029
transcription dna templated GO:0006351 377 0.029
enzyme linked receptor protein signaling pathway GO:0007167 116 0.029
ion homeostasis GO:0050801 212 0.028
chemical homeostasis GO:0048878 292 0.028
negative regulation of nucleic acid templated transcription GO:1903507 117 0.028
small gtpase mediated signal transduction GO:0007264 36 0.028
regulation of cell projection organization GO:0031344 175 0.028
immune system process GO:0002376 204 0.027
negative regulation of rna biosynthetic process GO:1902679 118 0.027
response to purine containing compound GO:0014074 126 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.026
protein complex subunit organization GO:0071822 302 0.025
regulation of membrane potential GO:0042391 110 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
multi organism reproductive process GO:0044703 262 0.023
organic acid metabolic process GO:0006082 292 0.023
neuron differentiation GO:0030182 368 0.023
response to external biotic stimulus GO:0043207 221 0.023
cellular catabolic process GO:0044248 295 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
multicellular organism reproduction GO:0032504 233 0.023
homeostatic process GO:0042592 331 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.022
negative regulation of cellular component organization GO:0051129 83 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
cellular component movement GO:0006928 248 0.022
cellular response to stress GO:0033554 269 0.022
macromolecule localization GO:0033036 252 0.022
regulation of transcription dna templated GO:0006355 374 0.021
reproductive process GO:0022414 372 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
regulation of nervous system development GO:0051960 264 0.021
single organism reproductive process GO:0044702 297 0.021
ion transmembrane transport GO:0034220 365 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
regulation of neuron differentiation GO:0045664 208 0.020
tissue development GO:0009888 252 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
regulation of protein transport GO:0051223 68 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.020
brain development GO:0007420 247 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
amine metabolic process GO:0009308 38 0.020
neuron development GO:0048666 286 0.020
cellular chemical homeostasis GO:0055082 247 0.020
immunoglobulin mediated immune response GO:0016064 4 0.020
vesicle mediated transport GO:0016192 181 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
response to oxygen levels GO:0070482 265 0.019
dendrite development GO:0016358 72 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
cytoplasmic transport GO:0016482 115 0.019
lipid metabolic process GO:0006629 283 0.019
peptidyl amino acid modification GO:0018193 126 0.019
positive regulation of cell communication GO:0010647 271 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
inorganic ion transmembrane transport GO:0098660 229 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
metal ion transport GO:0030001 289 0.018
response to lipopolysaccharide GO:0032496 191 0.017
regulation of cell proliferation GO:0042127 359 0.017
positive regulation of signal transduction GO:0009967 175 0.017
positive regulation of gene expression GO:0010628 244 0.017
response to amino acid GO:0043200 75 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
b cell activation involved in immune response GO:0002312 1 0.017
negative regulation of developmental process GO:0051093 125 0.017
nucleotide metabolic process GO:0009117 279 0.017
response to peptide hormone GO:0043434 278 0.017
gamete generation GO:0007276 124 0.016
organophosphate metabolic process GO:0019637 370 0.016
regulation of immunoglobulin production GO:0002637 4 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
striated muscle contraction GO:0006941 44 0.016
regulation of apoptotic process GO:0042981 335 0.016
apoptotic process GO:0006915 381 0.016
positive regulation of molecular function GO:0044093 230 0.016
positive regulation of transport GO:0051050 245 0.016
positive regulation of cell development GO:0010720 176 0.016
cellular cation homeostasis GO:0030003 180 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
response to decreased oxygen levels GO:0036293 237 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
response to carbohydrate GO:0009743 183 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
regulation of catabolic process GO:0009894 113 0.015
regulation of immune system process GO:0002682 123 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
response to alkaloid GO:0043279 132 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.014
protein transport GO:0015031 132 0.014
response to nutrient GO:0007584 248 0.014
regulation of rna metabolic process GO:0051252 391 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
cation transport GO:0006812 382 0.014
negative regulation of neuron differentiation GO:0045665 62 0.014
negative regulation of cell death GO:0060548 229 0.014
single organism organelle organization GO:1902589 180 0.014
regulation of response to stress GO:0080134 126 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
cellular component assembly GO:0022607 360 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
cation homeostasis GO:0055080 195 0.013
regulation of kinase activity GO:0043549 117 0.013
catabolic process GO:0009056 351 0.013
rho protein signal transduction GO:0007266 11 0.013
b cell mediated immunity GO:0019724 4 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
nitrogen compound transport GO:0071705 229 0.013
regulation of isotype switching GO:0045191 1 0.013
purine containing compound metabolic process GO:0072521 253 0.013
cellular amine metabolic process GO:0044106 38 0.013
negative regulation of signaling GO:0023057 157 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
protein modification by small protein conjugation GO:0032446 31 0.012
negative regulation of transport GO:0051051 136 0.012
positive regulation of protein modification process GO:0031401 142 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
cellular response to vitamin e GO:0071306 3 0.012
cell migration GO:0016477 197 0.012
carbohydrate metabolic process GO:0005975 130 0.012
cation transmembrane transport GO:0098655 263 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
cellular component biogenesis GO:0044085 368 0.012
regulation of mapk cascade GO:0043408 116 0.012
protein modification by small protein conjugation or removal GO:0070647 35 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
cellular ketone metabolic process GO:0042180 51 0.012
negative regulation of molecular function GO:0044092 133 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
cellular response to lipid GO:0071396 201 0.012
defense response GO:0006952 194 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
adult locomotory behavior GO:0008344 4 0.012
signal transduction by phosphorylation GO:0023014 144 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
regulation of neuron projection development GO:0010975 161 0.011
lymphocyte activation involved in immune response GO:0002285 3 0.011
maintenance of location GO:0051235 17 0.011
oxoacid metabolic process GO:0043436 290 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
protein localization GO:0008104 191 0.011
protein complex biogenesis GO:0070271 263 0.011
cell cell signaling GO:0007267 335 0.011
regulation of neurogenesis GO:0050767 247 0.011
double strand break repair GO:0006302 1 0.011
negative regulation of gene expression GO:0010629 199 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
response to vitamin GO:0033273 131 0.011
male gamete generation GO:0048232 99 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
positive regulation of hydrolase activity GO:0051345 86 0.010
protein ubiquitination GO:0016567 28 0.010
metal ion homeostasis GO:0055065 186 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.010
negative regulation of signal transduction GO:0009968 83 0.010
organ morphogenesis GO:0009887 75 0.010
lymphocyte activation GO:0046649 43 0.010
response to corticosteroid GO:0031960 235 0.010
regulation of leukocyte activation GO:0002694 45 0.010
regulation of ion transport GO:0043269 245 0.010
cell morphogenesis GO:0000902 142 0.010

Tpp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
central nervous system disease DOID:331 0 0.013