Rattus norvegicus

0 known processes

Nacc1

nucleus accumbens associated 1, BEN and BTB (POZ) domain containing

(Aliases: Btbd14b,Nac1,Nac-1)

Nacc1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
biological adhesion GO:0022610 110 0.219
carbohydrate derivative metabolic process GO:1901135 346 0.170
neuron development GO:0048666 286 0.136
positive regulation of developmental process GO:0051094 283 0.134
cellular component biogenesis GO:0044085 368 0.117
Human
regulation of cellular component organization GO:0051128 368 0.110
cell projection organization GO:0030030 302 0.109
exocytosis GO:0006887 60 0.106
neuron differentiation GO:0030182 368 0.100
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.099
cell cell junction organization GO:0045216 20 0.095
aromatic compound catabolic process GO:0019439 168 0.093
neuron projection development GO:0031175 273 0.091
membrane organization GO:0061024 94 0.090
cell adhesion GO:0007155 110 0.087
catabolic process GO:0009056 351 0.081
developmental process involved in reproduction GO:0003006 159 0.081
anatomical structure morphogenesis GO:0009653 298 0.078
carboxylic acid metabolic process GO:0019752 289 0.074
cellular component assembly GO:0022607 360 0.072
Human
response to extracellular stimulus GO:0009991 380 0.071
cellular response to external stimulus GO:0071496 118 0.067
synaptic vesicle endocytosis GO:0048488 4 0.067
regulation of cell differentiation GO:0045595 320 0.066
response to inorganic substance GO:0010035 377 0.065
cell substrate adhesion GO:0031589 29 0.064
single organism catabolic process GO:0044712 283 0.063
single organism organelle organization GO:1902589 180 0.062
regulation of catalytic activity GO:0050790 304 0.059
tissue development GO:0009888 252 0.057
regulation of kinase activity GO:0043549 117 0.055
multicellular organismal signaling GO:0035637 44 0.055
reproductive structure development GO:0048608 128 0.053
negative regulation of metabolic process GO:0009892 331 0.053
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.052
regulation of neurogenesis GO:0050767 247 0.052
reproductive process GO:0022414 372 0.051
brain development GO:0007420 247 0.051
response to corticosteroid GO:0031960 235 0.051
response to metal ion GO:0010038 253 0.050
response to insulin GO:0032868 133 0.050
regulation of protein kinase activity GO:0045859 105 0.049
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.049
dendrite morphogenesis GO:0048813 43 0.049
apoptotic process GO:0006915 381 0.049
positive regulation of neurogenesis GO:0050769 165 0.048
positive regulation of neuron projection development GO:0010976 99 0.048
synaptic vesicle exocytosis GO:0016079 15 0.046
positive regulation of nervous system development GO:0051962 178 0.046
synaptic growth at neuromuscular junction GO:0051124 1 0.046
purine ribonucleotide catabolic process GO:0009154 136 0.045
response to monosaccharide GO:0034284 159 0.045
regulation of programmed cell death GO:0043067 341 0.044
b cell differentiation GO:0030183 2 0.044
purine nucleoside metabolic process GO:0042278 169 0.044
purine nucleoside triphosphate metabolic process GO:0009144 141 0.043
regulation of cellular amine metabolic process GO:0033238 8 0.043
regulation of apoptotic process GO:0042981 335 0.043
organophosphate catabolic process GO:0046434 148 0.043
multi organism reproductive process GO:0044703 262 0.042
regulation of cell development GO:0060284 263 0.042
nucleobase containing small molecule metabolic process GO:0055086 316 0.042
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.041
regulation of cell morphogenesis GO:0022604 77 0.041
negative regulation of signaling GO:0023057 157 0.040
cellular amino acid metabolic process GO:0006520 107 0.040
gamete generation GO:0007276 124 0.040
head development GO:0060322 247 0.040
positive regulation of focal adhesion assembly GO:0051894 2 0.039
organelle organization GO:0006996 266 0.039
cell projection morphogenesis GO:0048858 123 0.039
cellular component morphogenesis GO:0032989 155 0.039
regulation of neuron projection development GO:0010975 161 0.039
cell morphogenesis involved in differentiation GO:0000904 119 0.039
positive regulation of cell communication GO:0010647 271 0.038
single organism reproductive process GO:0044702 297 0.038
generation of precursor metabolites and energy GO:0006091 62 0.037
cell part morphogenesis GO:0032990 123 0.037
axon development GO:0061564 96 0.037
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
regulation of phosphate metabolic process GO:0019220 349 0.037
positive regulation of cell projection organization GO:0031346 111 0.037
vesicle organization GO:0016050 29 0.037
ephrin receptor signaling pathway GO:0048013 3 0.037
vesicle mediated transport GO:0016192 181 0.036
organic substance catabolic process GO:1901575 316 0.036
cell matrix adhesion GO:0007160 19 0.035
ribonucleotide metabolic process GO:0009259 231 0.035
phototransduction visible light GO:0007603 2 0.035
response to acid chemical GO:0001101 222 0.035
transmembrane transport GO:0055085 412 0.035
nucleoside triphosphate catabolic process GO:0009143 123 0.034
response to nutrient levels GO:0031667 370 0.034
regulation of ion transmembrane transport GO:0034765 121 0.034
regulation of cell projection organization GO:0031344 175 0.034
establishment of organelle localization GO:0051656 37 0.034
organic acid metabolic process GO:0006082 292 0.034
regulation of cellular protein metabolic process GO:0032268 267 0.034
cell motility GO:0048870 202 0.033
regulation of transforming growth factor beta3 production GO:0032910 2 0.033
dendrite development GO:0016358 72 0.032
ras protein signal transduction GO:0007265 29 0.032
response to molecule of bacterial origin GO:0002237 194 0.032
cellular amine metabolic process GO:0044106 38 0.032
ribonucleotide catabolic process GO:0009261 136 0.032
response to peptide hormone GO:0043434 278 0.031
neurotransmitter transport GO:0006836 42 0.031
single organism carbohydrate metabolic process GO:0044723 118 0.031
reproduction GO:0000003 245 0.031
positive regulation of cellular component organization GO:0051130 200 0.031
organelle localization GO:0051640 55 0.031
bmp signaling pathway GO:0030509 4 0.031
detection of chemical stimulus GO:0009593 10 0.031
regulation of exocytosis GO:0017157 37 0.031
cell junction organization GO:0034330 21 0.031
regulation of b cell differentiation GO:0045577 1 0.031
nucleotide metabolic process GO:0009117 279 0.030
negative regulation of cell death GO:0060548 229 0.030
locomotion GO:0040011 237 0.030
positive regulation of neuron differentiation GO:0045666 126 0.030
negative regulation of cell communication GO:0010648 158 0.030
glycosyl compound metabolic process GO:1901657 182 0.030
regulation of protein metabolic process GO:0051246 289 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
Human
cell morphogenesis GO:0000902 142 0.029
regulation of nucleoside metabolic process GO:0009118 66 0.029
transforming growth factor beta3 production GO:0032907 2 0.029
positive regulation of cellular amine metabolic process GO:0033240 3 0.028
negative regulation of signal transduction GO:0009968 83 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
response to peptide GO:1901652 292 0.028
response to radiation GO:0009314 137 0.028
regulation of cell adhesion GO:0030155 52 0.027
cellular response to insulin stimulus GO:0032869 81 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
Human
nucleoside triphosphate metabolic process GO:0009141 144 0.027
jak stat cascade GO:0007259 26 0.027
nucleobase containing compound catabolic process GO:0034655 152 0.027
activation of phospholipase d activity GO:0031584 2 0.027
regulation of nervous system development GO:0051960 264 0.027
behavior GO:0007610 205 0.026
regulation of cell substrate adhesion GO:0010810 18 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
axonogenesis GO:0007409 71 0.026
ribonucleoside metabolic process GO:0009119 174 0.026
hexose metabolic process GO:0019318 58 0.026
cellular catabolic process GO:0044248 295 0.026
organophosphate metabolic process GO:0019637 370 0.025
organ morphogenesis GO:0009887 75 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
synaptic vesicle localization GO:0097479 24 0.025
cellular carbohydrate metabolic process GO:0044262 72 0.025
reproductive system development GO:0061458 128 0.025
neuron projection morphogenesis GO:0048812 122 0.025
single organism membrane organization GO:0044802 74 0.025
carbohydrate metabolic process GO:0005975 130 0.025
metal ion transport GO:0030001 289 0.025
peptidyl serine phosphorylation GO:0018105 33 0.025
purine containing compound catabolic process GO:0072523 138 0.024
heterocycle catabolic process GO:0046700 167 0.024
ribonucleoside triphosphate metabolic process GO:0009199 141 0.024
regulation of mapk cascade GO:0043408 116 0.024
regulation of proteasomal protein catabolic process GO:0061136 4 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
oxoacid metabolic process GO:0043436 290 0.024
monosaccharide metabolic process GO:0005996 61 0.024
regulation of hormone levels GO:0010817 187 0.024
positive regulation of signaling GO:0023056 270 0.024
gtp catabolic process GO:0006184 71 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
nucleotide catabolic process GO:0009166 139 0.023
central nervous system development GO:0007417 311 0.023
gland development GO:0048732 155 0.023
cation homeostasis GO:0055080 195 0.022
purine ribonucleoside metabolic process GO:0046128 168 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
Human
axis specification GO:0009798 4 0.022
cellular ketone metabolic process GO:0042180 51 0.022
heart morphogenesis GO:0003007 3 0.022
macromolecular complex assembly GO:0065003 273 0.022
Human
establishment of synaptic vesicle localization GO:0097480 23 0.022
proteolysis GO:0006508 175 0.022
pro t cell differentiation GO:0002572 1 0.022
glycosyl compound catabolic process GO:1901658 126 0.021
amide transport GO:0042886 105 0.021
purine containing compound metabolic process GO:0072521 253 0.021
cerebral cortex tangential migration GO:0021800 1 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
positive regulation of protein kinase activity GO:0045860 73 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
wound healing GO:0042060 122 0.021
response to hydrogen peroxide GO:0042542 89 0.021
translation GO:0006412 35 0.020
response to oxidative stress GO:0006979 186 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
positive regulation of inhibitory postsynaptic membrane potential GO:0097151 3 0.020
actin cytoskeleton organization GO:0030036 73 0.020
cellular lipid metabolic process GO:0044255 208 0.019
protein complex assembly GO:0006461 263 0.019
Human
intracellular signal transduction GO:0035556 314 0.019
rna metabolic process GO:0016070 406 0.019
Human
positive regulation of rna metabolic process GO:0051254 203 0.019
cell cell signaling GO:0007267 335 0.019
carbohydrate derivative catabolic process GO:1901136 147 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
lipid modification GO:0030258 52 0.019
regulation of phosphorylation GO:0042325 248 0.019
ribonucleoside catabolic process GO:0042454 126 0.018
urogenital system development GO:0001655 78 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
neurotransmitter secretion GO:0007269 33 0.018
regulation of smooth muscle cell proliferation GO:0048660 75 0.018
regulation of ion transport GO:0043269 245 0.018
positive regulation of protein modification process GO:0031401 142 0.018
response to glucocorticoid GO:0051384 223 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
lymphoid progenitor cell differentiation GO:0002320 2 0.018
negative regulation of transport GO:0051051 136 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.018
lipid metabolic process GO:0006629 283 0.018
secretion GO:0046903 307 0.018
cytoskeleton organization GO:0007010 111 0.017
organelle fusion GO:0048284 17 0.017
multicellular organism growth GO:0035264 1 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
regeneration GO:0031099 163 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
energy derivation by oxidation of organic compounds GO:0015980 46 0.017
ion transmembrane transport GO:0034220 365 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
programmed cell death GO:0012501 392 0.017
response to hexose GO:0009746 144 0.017
response to estrogen GO:0043627 232 0.017
positive regulation of nucleoside metabolic process GO:0045979 55 0.017
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.017
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.017
peptidyl amino acid modification GO:0018193 126 0.017
response to mechanical stimulus GO:0009612 134 0.017
positive regulation of transport GO:0051050 245 0.017
regulation of generation of precursor metabolites and energy GO:0043467 18 0.017
endoplasmic reticulum organization GO:0007029 1 0.016
regulation of growth GO:0040008 105 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
signal release GO:0023061 145 0.016
nucleoside metabolic process GO:0009116 179 0.016
endomembrane system organization GO:0010256 48 0.016
response to reactive oxygen species GO:0000302 120 0.016
homeostatic process GO:0042592 331 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
response to ionizing radiation GO:0010212 59 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
Human
sexual reproduction GO:0019953 148 0.016
adult locomotory behavior GO:0008344 4 0.016
multicellular organism reproduction GO:0032504 233 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
protein phosphorylation GO:0006468 345 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
spermatogenesis GO:0007283 99 0.015
membrane fusion GO:0061025 26 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
regulation of lipid metabolic process GO:0019216 68 0.015
smad protein complex assembly GO:0007183 1 0.015
vesicle fusion GO:0006906 14 0.015
response to carbohydrate GO:0009743 183 0.015
glucose metabolic process GO:0006006 52 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
positive regulation of locomotion GO:0040017 102 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
male gamete generation GO:0048232 99 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
Human
olfactory behavior GO:0042048 2 0.015
localization of cell GO:0051674 202 0.015
cellular response to alcohol GO:0097306 87 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
male sex differentiation GO:0046661 64 0.015
anterior posterior pattern specification GO:0009952 1 0.015
immune system process GO:0002376 204 0.015
peptidyl serine modification GO:0018209 34 0.015
synaptic transmission GO:0007268 235 0.015
response to vitamin GO:0033273 131 0.015
regulation of molecular function GO:0065009 398 0.014
ion homeostasis GO:0050801 212 0.014
motor neuron axon guidance GO:0008045 1 0.014
epithelial cell differentiation GO:0030855 71 0.014
positive regulation of odontogenesis of dentin containing tooth GO:0042488 1 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
growth GO:0040007 165 0.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.014
chemosensory behavior GO:0007635 2 0.014
response to cytokine GO:0034097 215 0.014
response to nutrient GO:0007584 248 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
Human
response to camp GO:0051591 91 0.014
negative regulation of gene expression GO:0010629 199 0.014
Human
cellular response to stress GO:0033554 269 0.014
cell substrate adherens junction assembly GO:0007045 10 0.014
regulation of vesicle mediated transport GO:0060627 81 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.014
detection of visible light GO:0009584 3 0.014
positive regulation of molecular function GO:0044093 230 0.014
single organism biosynthetic process GO:0044711 342 0.013
fatty acid oxidation GO:0019395 29 0.013
rhythmic process GO:0048511 156 0.013
sex differentiation GO:0007548 113 0.013
cation transport GO:0006812 382 0.013
embryonic pattern specification GO:0009880 1 0.013
nucleic acid templated transcription GO:0097659 379 0.013
Human
b cell activation involved in immune response GO:0002312 1 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
leukocyte differentiation GO:0002521 30 0.013
positive regulation of transferase activity GO:0051347 81 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.013
gastrulation GO:0007369 2 0.013
transmission of nerve impulse GO:0019226 42 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
regulation of peptide hormone secretion GO:0090276 80 0.013
outer mitochondrial membrane organization GO:0007008 1 0.013
mitotic spindle organization GO:0007052 2 0.013
spindle organization GO:0007051 2 0.013
macromolecule localization GO:0033036 252 0.013
intracellular transport GO:0046907 185 0.013
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.013
chromosome segregation GO:0007059 2 0.013
sensory organ development GO:0007423 74 0.013
neurological system process GO:0050877 219 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
regulation of membrane potential GO:0042391 110 0.013
positive regulation of cell development GO:0010720 176 0.013
single organism cellular localization GO:1902580 102 0.012
positive regulation of cell death GO:0010942 184 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
response to glucose GO:0009749 136 0.012
regulation of transferase activity GO:0051338 123 0.012
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.012
regulation of carbohydrate metabolic process GO:0006109 41 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
positive regulation of gene expression GO:0010628 244 0.012
response to uv c GO:0010225 2 0.012
synaptic vesicle transport GO:0048489 23 0.012
neuronal action potential GO:0019228 35 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
positive regulation of adherens junction organization GO:1903393 2 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
anion transport GO:0006820 178 0.012
response to biotic stimulus GO:0009607 226 0.012
regulation of transmembrane transport GO:0034762 122 0.012
secretion by cell GO:0032940 248 0.012
epithelium development GO:0060429 96 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
protein processing GO:0016485 68 0.012
cellular homeostasis GO:0019725 252 0.012
regulation of nitric oxide synthase activity GO:0050999 8 0.012
regulation of cell motility GO:2000145 131 0.012
dephosphorylation GO:0016311 98 0.012
negative regulation of intracellular signal transduction GO:1902532 38 0.012
male gonad development GO:0008584 59 0.012
protein maturation GO:0051604 68 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
regulation of dendrite development GO:0050773 59 0.012
single organism intracellular transport GO:1902582 166 0.012
positive regulation of mitochondrion organization GO:0010822 4 0.012
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.012
regulation of neuron differentiation GO:0045664 208 0.011
regulation of transcription dna templated GO:0006355 374 0.011
Human
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.011
intestinal absorption GO:0050892 3 0.011
asymmetric protein localization GO:0008105 2 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
positive regulation of chemotaxis GO:0050921 23 0.011
regulation of ion transmembrane transporter activity GO:0032412 48 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
gliogenesis GO:0042063 93 0.011
cellular component movement GO:0006928 248 0.011
adenosine receptor signaling pathway GO:0001973 7 0.011
response to oxygen levels GO:0070482 265 0.011
lipid storage GO:0019915 1 0.011
rna localization GO:0006403 4 0.011
positive regulation of exocytosis GO:0045921 19 0.011
response to ketone GO:1901654 182 0.011
chemical homeostasis GO:0048878 292 0.011
regulation of embryonic development GO:0045995 2 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
regulation of signal transduction GO:0009966 318 0.011
myeloid leukocyte differentiation GO:0002573 20 0.011
peptide transport GO:0015833 97 0.011
response to other organism GO:0051707 220 0.011
development of primary male sexual characteristics GO:0046546 59 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
response to bacterium GO:0009617 200 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
response to mineralocorticoid GO:0051385 49 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
Human
gtp metabolic process GO:0046039 72 0.011
regulation of glucose metabolic process GO:0010906 23 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
positive regulation of transcription factor import into nucleus GO:0042993 4 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
regulation of notch signaling pathway GO:0008593 3 0.010
response to external biotic stimulus GO:0043207 221 0.010
single organism behavior GO:0044708 130 0.010
muscle cell proliferation GO:0033002 84 0.010
calcium ion transport GO:0006816 131 0.010
amine metabolic process GO:0009308 38 0.010
positive regulation of protein metabolic process GO:0051247 178 0.010
regulation of gtpase activity GO:0043087 57 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
cation transmembrane transport GO:0098655 263 0.010
response to hypoxia GO:0001666 231 0.010
myelination GO:0042552 39 0.010
cell cycle checkpoint GO:0000075 2 0.010

Nacc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
sensory system disease DOID:0050155 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
disease of metabolism DOID:0014667 0 0.011
musculoskeletal system disease DOID:17 0 0.011