Rattus norvegicus

5 known processes

Clcn6

chloride channel 6

Clcn6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component organization GO:0051128 368 0.264
organophosphate metabolic process GO:0019637 370 0.116
positive regulation of multicellular organismal process GO:0051240 387 0.098
neuron differentiation GO:0030182 368 0.095
neuron projection development GO:0031175 273 0.094
regulation of multicellular organismal development GO:2000026 376 0.090
macromolecular complex subunit organization GO:0043933 339 0.089
regulation of nervous system development GO:0051960 264 0.081
cell projection organization GO:0030030 302 0.074
intracellular signal transduction GO:0035556 314 0.069
regulation of phosphorus metabolic process GO:0051174 349 0.069
organelle organization GO:0006996 266 0.069
cellular component biogenesis GO:0044085 368 0.068
cell cell signaling GO:0007267 335 0.068
cellular catabolic process GO:0044248 295 0.066
regulation of phosphate metabolic process GO:0019220 349 0.065
positive regulation of phosphate metabolic process GO:0045937 262 0.064
regulation of neuron projection development GO:0010975 161 0.062
protein phosphorylation GO:0006468 345 0.061
programmed cell death GO:0012501 392 0.061
cellular component assembly GO:0022607 360 0.060
negative regulation of metabolic process GO:0009892 331 0.057
regulation of neurogenesis GO:0050767 247 0.055
nucleotide metabolic process GO:0009117 279 0.055
vesicle mediated transport GO:0016192 181 0.054
nucleobase containing small molecule metabolic process GO:0055086 316 0.053
ion transmembrane transport GO:0034220 365 0.053
Rat
endocytosis GO:0006897 84 0.052
regulation of signal transduction GO:0009966 318 0.052
purine containing compound metabolic process GO:0072521 253 0.052
regulation of neuron differentiation GO:0045664 208 0.051
aromatic compound catabolic process GO:0019439 168 0.049
regulation of cell differentiation GO:0045595 320 0.048
protein complex subunit organization GO:0071822 302 0.046
cellular response to oxygen containing compound GO:1901701 386 0.046
positive regulation of neurogenesis GO:0050769 165 0.045
ribonucleotide metabolic process GO:0009259 231 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.044
regulation of cell development GO:0060284 263 0.043
positive regulation of neuron differentiation GO:0045666 126 0.042
amine metabolic process GO:0009308 38 0.042
positive regulation of cellular component organization GO:0051130 200 0.041
protein localization GO:0008104 191 0.041
regulation of anatomical structure morphogenesis GO:0022603 141 0.041
neuron projection morphogenesis GO:0048812 122 0.041
nucleoside phosphate metabolic process GO:0006753 283 0.040
macromolecule localization GO:0033036 252 0.039
positive regulation of developmental process GO:0051094 283 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
catabolic process GO:0009056 351 0.039
reproductive process GO:0022414 372 0.039
ribose phosphate metabolic process GO:0019693 235 0.037
anatomical structure morphogenesis GO:0009653 298 0.037
single organism organelle organization GO:1902589 180 0.037
organic hydroxy compound metabolic process GO:1901615 115 0.037
synaptic transmission GO:0007268 235 0.037
purine nucleotide metabolic process GO:0006163 229 0.037
intracellular transport GO:0046907 185 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.037
regulation of phosphorylation GO:0042325 248 0.037
positive regulation of neuron projection development GO:0010976 99 0.037
purine ribonucleotide metabolic process GO:0009150 227 0.036
macromolecular complex assembly GO:0065003 273 0.036
homeostatic process GO:0042592 331 0.036
organophosphate biosynthetic process GO:0090407 143 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.034
synaptic growth at neuromuscular junction GO:0051124 1 0.033
neuron development GO:0048666 286 0.033
positive regulation of signaling GO:0023056 270 0.033
cellular component movement GO:0006928 248 0.033
regulation of cellular localization GO:0060341 263 0.032
regulation of catalytic activity GO:0050790 304 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
positive regulation of nervous system development GO:0051962 178 0.032
organic cyclic compound catabolic process GO:1901361 175 0.031
axonogenesis GO:0007409 71 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
protein complex assembly GO:0006461 263 0.031
cellular component morphogenesis GO:0032989 155 0.030
cell morphogenesis involved in differentiation GO:0000904 119 0.030
lipid metabolic process GO:0006629 283 0.030
organic substance catabolic process GO:1901575 316 0.030
nucleoside metabolic process GO:0009116 179 0.030
cellular protein localization GO:0034613 122 0.030
single organism intracellular transport GO:1902582 166 0.030
small gtpase mediated signal transduction GO:0007264 36 0.030
central nervous system development GO:0007417 311 0.029
axon development GO:0061564 96 0.029
chemical homeostasis GO:0048878 292 0.029
cation transport GO:0006812 382 0.029
purine containing compound catabolic process GO:0072523 138 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
protein complex biogenesis GO:0070271 263 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
nucleoside triphosphate catabolic process GO:0009143 123 0.028
rna metabolic process GO:0016070 406 0.028
positive regulation of cell communication GO:0010647 271 0.028
response to carbohydrate GO:0009743 183 0.028
cellular amine metabolic process GO:0044106 38 0.028
transmembrane transport GO:0055085 412 0.028
Rat
regulation of anatomical structure size GO:0090066 135 0.027
response to inorganic substance GO:0010035 377 0.027
regulation of cell projection organization GO:0031344 175 0.027
glycosyl compound metabolic process GO:1901657 182 0.027
ras protein signal transduction GO:0007265 29 0.026
single organism biosynthetic process GO:0044711 342 0.026
single organism catabolic process GO:0044712 283 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
positive regulation of molecular function GO:0044093 230 0.026
regulation of nucleotide metabolic process GO:0006140 117 0.026
negative regulation of signaling GO:0023057 157 0.025
rna biosynthetic process GO:0032774 380 0.025
regulation of axonogenesis GO:0050770 37 0.025
positive regulation of cell projection organization GO:0031346 111 0.025
regulation of cell morphogenesis GO:0022604 77 0.025
regulation of apoptotic process GO:0042981 335 0.025
ribonucleoside metabolic process GO:0009119 174 0.025
regulation of molecular function GO:0065009 398 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.025
transcription dna templated GO:0006351 377 0.025
nucleic acid templated transcription GO:0097659 379 0.025
purine nucleotide catabolic process GO:0006195 136 0.024
organophosphate catabolic process GO:0046434 148 0.024
head development GO:0060322 247 0.024
positive regulation of cell development GO:0010720 176 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.024
growth GO:0040007 165 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
nucleoside triphosphate metabolic process GO:0009141 144 0.024
purine nucleoside catabolic process GO:0006152 124 0.024
heterocycle catabolic process GO:0046700 167 0.024
ribonucleotide catabolic process GO:0009261 136 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
cell morphogenesis GO:0000902 142 0.023
regulation of ion transport GO:0043269 245 0.023
Rat
single organism reproductive process GO:0044702 297 0.023
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.023
nucleoside phosphate catabolic process GO:1901292 140 0.023
negative regulation of developmental process GO:0051093 125 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
cellular nitrogen compound catabolic process GO:0044270 163 0.023
nucleoside catabolic process GO:0009164 126 0.023
regulation of cell growth GO:0001558 85 0.022
nitrogen compound transport GO:0071705 229 0.022
anion transport GO:0006820 178 0.022
Rat
organonitrogen compound catabolic process GO:1901565 179 0.022
ribonucleoside catabolic process GO:0042454 126 0.022
cell projection morphogenesis GO:0048858 123 0.022
negative regulation of cellular component organization GO:0051129 83 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
response to nutrient levels GO:0031667 370 0.022
regulation of growth GO:0040008 105 0.021
cell migration GO:0016477 197 0.021
multi organism reproductive process GO:0044703 262 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
multicellular organism reproduction GO:0032504 233 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
cellular homeostasis GO:0019725 252 0.021
neuron apoptotic process GO:0051402 88 0.021
negative regulation of cell communication GO:0010648 158 0.021
purine ribonucleotide catabolic process GO:0009154 136 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
purine nucleoside triphosphate catabolic process GO:0009146 122 0.021
cellular response to stress GO:0033554 269 0.021
response to extracellular stimulus GO:0009991 380 0.021
regulation of programmed cell death GO:0043067 341 0.020
protein oligomerization GO:0051259 191 0.020
nucleotide catabolic process GO:0009166 139 0.020
organic acid metabolic process GO:0006082 292 0.020
regulation of protein metabolic process GO:0051246 289 0.020
regulation of protein modification process GO:0031399 194 0.020
response to peptide GO:1901652 292 0.020
cellular lipid metabolic process GO:0044255 208 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
purine ribonucleoside catabolic process GO:0046130 124 0.020
apoptotic process GO:0006915 381 0.020
negative regulation of gene expression GO:0010629 199 0.020
cell type specific apoptotic process GO:0097285 134 0.020
developmental process involved in reproduction GO:0003006 159 0.020
establishment of protein localization GO:0045184 141 0.020
reproduction GO:0000003 245 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
localization of cell GO:0051674 202 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
signal release GO:0023061 145 0.019
developmental growth GO:0048589 100 0.019
brain development GO:0007420 247 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
cell growth GO:0016049 104 0.019
protein homooligomerization GO:0051260 91 0.019
positive regulation of cell death GO:0010942 184 0.019
response to growth factor GO:0070848 189 0.019
regulation of synaptic transmission GO:0050804 141 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
regulation of membrane potential GO:0042391 110 0.018
ribonucleoside triphosphate catabolic process GO:0009203 122 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
aging GO:0007568 241 0.018
organic anion transport GO:0015711 132 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
gtp catabolic process GO:0006184 71 0.018
regulation of hydrolase activity GO:0051336 143 0.018
locomotion GO:0040011 237 0.017
regulation of cellular component biogenesis GO:0044087 86 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
metal ion transport GO:0030001 289 0.017
response to metal ion GO:0010038 253 0.017
cytoskeleton organization GO:0007010 111 0.017
cytoplasmic transport GO:0016482 115 0.017
negative regulation of neuron differentiation GO:0045665 62 0.017
gamete generation GO:0007276 124 0.017
regulation of gtpase activity GO:0043087 57 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
positive regulation of signal transduction GO:0009967 175 0.017
positive regulation of catalytic activity GO:0043085 184 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
regulation of catabolic process GO:0009894 113 0.016
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
secretion by cell GO:0032940 248 0.016
muscle system process GO:0003012 115 0.016
organic acid transport GO:0015849 116 0.016
neurological system process GO:0050877 219 0.016
negative regulation of transport GO:0051051 136 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.016
positive regulation of neuron death GO:1901216 43 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
cell motility GO:0048870 202 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
behavior GO:0007610 205 0.016
secretion GO:0046903 307 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
response to monosaccharide GO:0034284 159 0.015
response to oxygen levels GO:0070482 265 0.015
positive regulation of gene expression GO:0010628 244 0.015
response to purine containing compound GO:0014074 126 0.015
response to peptide hormone GO:0043434 278 0.015
neuron death GO:0070997 127 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
motor neuron axon guidance GO:0008045 1 0.015
sexual reproduction GO:0019953 148 0.015
regulation of protein localization GO:0032880 81 0.015
regulation of hormone levels GO:0010817 187 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
cellular response to lipid GO:0071396 201 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
regulation of system process GO:0044057 208 0.014
spindle organization GO:0007051 2 0.014
positive regulation of protein modification process GO:0031401 142 0.014
regulation of protein kinase activity GO:0045859 105 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
embryonic pattern specification GO:0009880 1 0.014
defense response GO:0006952 194 0.014
response to nutrient GO:0007584 248 0.014
membrane organization GO:0061024 94 0.014
oxoacid metabolic process GO:0043436 290 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
regulation of vesicle mediated transport GO:0060627 81 0.013
response to acid chemical GO:0001101 222 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
mitotic spindle organization GO:0007052 2 0.013
oxidation reduction process GO:0055114 304 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
phospholipid metabolic process GO:0006644 61 0.013
response to ethanol GO:0045471 162 0.013
anterior posterior pattern specification GO:0009952 1 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
response to cytokine GO:0034097 215 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
synapse assembly GO:0007416 29 0.013
cellular ketone metabolic process GO:0042180 51 0.013
response to glucose GO:0009749 136 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
cellular macromolecule localization GO:0070727 122 0.012
regulation of rna metabolic process GO:0051252 391 0.012
gastrulation GO:0007369 2 0.012
single organism membrane organization GO:0044802 74 0.012
reproductive system development GO:0061458 128 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
response to vitamin GO:0033273 131 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
response to insulin GO:0032868 133 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
regulation of ras protein signal transduction GO:0046578 45 0.012
cell part morphogenesis GO:0032990 123 0.012
small molecule biosynthetic process GO:0044283 124 0.012
regulation of intracellular transport GO:0032386 65 0.012
transmission of nerve impulse GO:0019226 42 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
regulation of cell proliferation GO:0042127 359 0.012
response to oxidative stress GO:0006979 186 0.012
response to alkaloid GO:0043279 132 0.012
proteolysis GO:0006508 175 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
response to corticosteroid GO:0031960 235 0.012
neuron neuron synaptic transmission GO:0007270 60 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
gtp metabolic process GO:0046039 72 0.012
response to organophosphorus GO:0046683 102 0.012
tissue development GO:0009888 252 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
protein localization to membrane GO:0072657 36 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
circulatory system development GO:0072359 134 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
actin filament based process GO:0030029 86 0.012
development of primary sexual characteristics GO:0045137 107 0.012
mapk cascade GO:0000165 140 0.012
actin cytoskeleton organization GO:0030036 73 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of axon extension GO:0030516 24 0.011
cellular ion homeostasis GO:0006873 184 0.011
response to toxic substance GO:0009636 133 0.011
blood circulation GO:0008015 183 0.011
positive regulation of secretion GO:0051047 140 0.011
regulation of rab protein signal transduction GO:0032483 3 0.011
negative regulation of neuron projection development GO:0010977 46 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
dna metabolic process GO:0006259 96 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
cellular chemical homeostasis GO:0055082 247 0.011
regulation of transcription dna templated GO:0006355 374 0.011
regulation of organelle organization GO:0033043 80 0.011
glycerolipid metabolic process GO:0046486 67 0.011
carboxylic acid transport GO:0046942 115 0.011
regulation of response to stress GO:0080134 126 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
sex differentiation GO:0007548 113 0.011
protein transport GO:0015031 132 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
negative regulation of nervous system development GO:0051961 79 0.011
hormone secretion GO:0046879 115 0.011
axis specification GO:0009798 4 0.011
regulation of secretion GO:0051046 224 0.011
regulation of transferase activity GO:0051338 123 0.011
organ formation GO:0048645 3 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
regulation of kinase activity GO:0043549 117 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.010
positive regulation of ion transport GO:0043270 94 0.010
hormone transport GO:0009914 121 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
response to hexose GO:0009746 144 0.010
regulation of embryonic development GO:0045995 2 0.010
response to decreased oxygen levels GO:0036293 237 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
Rat
chromosome segregation GO:0007059 2 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
forebrain development GO:0030900 98 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
response to amine GO:0014075 46 0.010
positive regulation of nucleoside metabolic process GO:0045979 55 0.010
regulation of small gtpase mediated signal transduction GO:0051056 48 0.010

Clcn6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
central nervous system disease DOID:331 0 0.017