Rattus norvegicus

33 known processes

Hadhb

hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit

Hadhb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.886
monocarboxylic acid metabolic process GO:0032787 152 0.856
acyl coa metabolic process GO:0006637 28 0.769
carboxylic acid metabolic process GO:0019752 289 0.767
monocarboxylic acid catabolic process GO:0072329 28 0.754
oxidation reduction process GO:0055114 304 0.745
fatty acid beta oxidation GO:0006635 22 0.727
single organism biosynthetic process GO:0044711 342 0.707
organic acid metabolic process GO:0006082 292 0.649
cofactor metabolic process GO:0051186 95 0.625
cellular lipid metabolic process GO:0044255 208 0.575
generation of precursor metabolites and energy GO:0006091 62 0.555
lipid oxidation GO:0034440 30 0.468
cellular catabolic process GO:0044248 295 0.414
homeostatic process GO:0042592 331 0.413
energy derivation by oxidation of organic compounds GO:0015980 46 0.398
organic acid catabolic process GO:0016054 49 0.368
small molecule biosynthetic process GO:0044283 124 0.342
response to nutrient levels GO:0031667 370 0.327
single organism catabolic process GO:0044712 283 0.300
programmed cell death GO:0012501 392 0.253
small molecule catabolic process GO:0044282 59 0.227
fatty acid oxidation GO:0019395 29 0.211
acetyl coa metabolic process GO:0006084 17 0.201
thioester metabolic process GO:0035383 28 0.201
organophosphate metabolic process GO:0019637 370 0.195
organic substance catabolic process GO:1901575 316 0.194
cellular lipid catabolic process GO:0044242 37 0.154
nucleotide metabolic process GO:0009117 279 0.153
nucleoside triphosphate metabolic process GO:0009141 144 0.150
cellular polysaccharide metabolic process GO:0044264 23 0.148
regulation of programmed cell death GO:0043067 341 0.135
apoptotic process GO:0006915 381 0.128
cellular respiration GO:0045333 21 0.127
negative regulation of cellular metabolic process GO:0031324 281 0.120
nucleoside phosphate metabolic process GO:0006753 283 0.110
fatty acid metabolic process GO:0006631 99 0.109
organic hydroxy compound metabolic process GO:1901615 115 0.109
anion transport GO:0006820 178 0.102
regulation of catabolic process GO:0009894 113 0.101
carboxylic acid catabolic process GO:0046395 49 0.101
regulation of apoptotic process GO:0042981 335 0.099
regulation of cellular localization GO:0060341 263 0.090
fatty acid catabolic process GO:0009062 26 0.090
coenzyme metabolic process GO:0006732 86 0.089
lipid localization GO:0010876 62 0.088
cellular ketone metabolic process GO:0042180 51 0.080
tricarboxylic acid metabolic process GO:0072350 10 0.076
protein complex subunit organization GO:0071822 302 0.075
cellular component biogenesis GO:0044085 368 0.075
purine nucleotide metabolic process GO:0006163 229 0.075
lipid modification GO:0030258 52 0.073
long chain fatty acid metabolic process GO:0001676 32 0.071
organic acid transport GO:0015849 116 0.071
gland development GO:0048732 155 0.068
positive regulation of mitochondrial membrane permeability GO:0035794 1 0.066
nucleobase containing small molecule metabolic process GO:0055086 316 0.065
negative regulation of metabolic process GO:0009892 331 0.062
cellular component assembly GO:0022607 360 0.062
dicarboxylic acid metabolic process GO:0043648 42 0.061
cell type specific apoptotic process GO:0097285 134 0.061
organelle organization GO:0006996 266 0.060
developmental process involved in reproduction GO:0003006 159 0.059
response to extracellular stimulus GO:0009991 380 0.058
lipid catabolic process GO:0016042 46 0.058
carboxylic acid transport GO:0046942 115 0.057
response to inorganic substance GO:0010035 377 0.057
secretion by cell GO:0032940 248 0.055
purine ribonucleotide metabolic process GO:0009150 227 0.053
regulation of cellular ketone metabolic process GO:0010565 27 0.053
regulation of nucleic acid templated transcription GO:1903506 380 0.053
reproductive process GO:0022414 372 0.053
lipid metabolic process GO:0006629 283 0.052
positive regulation of cell death GO:0010942 184 0.051
protein complex assembly GO:0006461 263 0.050
regulation of cholesterol metabolic process GO:0090181 5 0.050
steroid metabolic process GO:0008202 73 0.050
regulation of transcription dna templated GO:0006355 374 0.050
response to oxidative stress GO:0006979 186 0.049
macromolecular complex subunit organization GO:0043933 339 0.047
negative regulation of cellular biosynthetic process GO:0031327 161 0.047
regulation of protein metabolic process GO:0051246 289 0.046
ribonucleotide metabolic process GO:0009259 231 0.046
regulation of phosphorylation GO:0042325 248 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.045
regulation of phosphorus metabolic process GO:0051174 349 0.044
positive regulation of molecular function GO:0044093 230 0.044
negative regulation of programmed cell death GO:0043069 183 0.042
glycogen metabolic process GO:0005977 23 0.042
l glutamate import GO:0051938 2 0.041
glucan biosynthetic process GO:0009250 15 0.041
response to reactive oxygen species GO:0000302 120 0.041
fatty acid biosynthetic process GO:0006633 33 0.041
cell cell signaling GO:0007267 335 0.040
secretion GO:0046903 307 0.040
polysaccharide metabolic process GO:0005976 25 0.040
negative regulation of biosynthetic process GO:0009890 168 0.039
tricarboxylic acid cycle GO:0006099 11 0.039
protein complex biogenesis GO:0070271 263 0.039
chemical homeostasis GO:0048878 292 0.038
atp metabolic process GO:0046034 72 0.038
organic anion transport GO:0015711 132 0.038
sulfur compound metabolic process GO:0006790 70 0.038
growth GO:0040007 165 0.037
lipid biosynthetic process GO:0008610 128 0.037
cellular response to organic cyclic compound GO:0071407 202 0.037
transcription dna templated GO:0006351 377 0.037
ribonucleoside metabolic process GO:0009119 174 0.037
response to estrogen GO:0043627 232 0.036
neuron apoptotic process GO:0051402 88 0.036
single organism organelle organization GO:1902589 180 0.036
regulation of fatty acid metabolic process GO:0019217 18 0.036
regulation of rna biosynthetic process GO:2001141 381 0.035
peptide hormone secretion GO:0030072 84 0.035
carboxylic acid biosynthetic process GO:0046394 83 0.035
anatomical structure morphogenesis GO:0009653 298 0.034
purine containing compound metabolic process GO:0072521 253 0.034
single organism intracellular transport GO:1902582 166 0.034
positive regulation of programmed cell death GO:0043068 157 0.034
regulation of homeostatic process GO:0032844 101 0.034
glycerolipid metabolic process GO:0046486 67 0.033
regulation of fatty acid oxidation GO:0046320 10 0.033
regulation of hormone levels GO:0010817 187 0.033
glycogen biosynthetic process GO:0005978 15 0.032
cellular homeostasis GO:0019725 252 0.032
hexose metabolic process GO:0019318 58 0.032
nitrogen compound transport GO:0071705 229 0.032
negative regulation of signaling GO:0023057 157 0.031
cellular amine metabolic process GO:0044106 38 0.031
single organism carbohydrate metabolic process GO:0044723 118 0.031
multicellular organism reproduction GO:0032504 233 0.031
oxidative phosphorylation GO:0006119 4 0.031
reproduction GO:0000003 245 0.031
monocarboxylic acid biosynthetic process GO:0072330 48 0.031
regulation of cellular component organization GO:0051128 368 0.030
response to cytokine GO:0034097 215 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
cellular chemical homeostasis GO:0055082 247 0.029
aerobic respiration GO:0009060 13 0.029
nucleic acid templated transcription GO:0097659 379 0.029
cellular response to nitrogen compound GO:1901699 210 0.028
cellular response to oxidative stress GO:0034599 76 0.028
response to nutrient GO:0007584 248 0.028
ribonucleoside triphosphate metabolic process GO:0009199 141 0.027
cellular glucan metabolic process GO:0006073 23 0.027
energy reserve metabolic process GO:0006112 25 0.027
catabolic process GO:0009056 351 0.027
response to hypoxia GO:0001666 231 0.027
negative regulation of apoptotic process GO:0043066 181 0.027
aging GO:0007568 241 0.027
Fly
regulation of phosphate metabolic process GO:0019220 349 0.027
tissue development GO:0009888 252 0.027
rna biosynthetic process GO:0032774 380 0.026
regulation of catalytic activity GO:0050790 304 0.026
reproductive system development GO:0061458 128 0.026
response to oxygen levels GO:0070482 265 0.025
purine nucleoside metabolic process GO:0042278 169 0.025
citrate metabolic process GO:0006101 3 0.025
regulation of secretion GO:0051046 224 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
ion transmembrane transport GO:0034220 365 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
phosphatidylethanolamine metabolic process GO:0046337 1 0.025
regulation of rna metabolic process GO:0051252 391 0.025
transmembrane transport GO:0055085 412 0.025
anion transmembrane transport GO:0098656 77 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
regulation of peptide transport GO:0090087 87 0.024
regulation of hydrolase activity GO:0051336 143 0.024
cellular response to stress GO:0033554 269 0.024
insulin secretion GO:0030073 69 0.024
amine metabolic process GO:0009308 38 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
regulation of fatty acid beta oxidation GO:0031998 8 0.023
peptide secretion GO:0002790 86 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
ribonucleoside monophosphate metabolic process GO:0009161 88 0.023
regulation of cellular catabolic process GO:0031329 101 0.023
hormone transport GO:0009914 121 0.022
atp synthesis coupled electron transport GO:0042773 2 0.022
carnitine metabolic process GO:0009437 3 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
muscle structure development GO:0061061 87 0.022
reactive oxygen species metabolic process GO:0072593 37 0.022
negative regulation of cell communication GO:0010648 158 0.022
long chain fatty acid transport GO:0015909 14 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
purine nucleoside monophosphate metabolic process GO:0009126 84 0.021
regulation of hormone secretion GO:0046883 106 0.021
membrane organization GO:0061024 94 0.021
cell morphogenesis GO:0000902 142 0.021
macromolecular complex assembly GO:0065003 273 0.021
head development GO:0060322 247 0.021
rna metabolic process GO:0016070 406 0.021
single organism reproductive process GO:0044702 297 0.021
cellular response to oxygen containing compound GO:1901701 386 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
fatty acyl coa metabolic process GO:0035337 1 0.020
polysaccharide biosynthetic process GO:0000271 16 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
regulation of gluconeogenesis GO:0006111 4 0.020
cellular response to reactive oxygen species GO:0034614 55 0.020
cation homeostasis GO:0055080 195 0.020
intracellular transport GO:0046907 185 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
response to decreased oxygen levels GO:0036293 237 0.019
regulation of peptide hormone secretion GO:0090276 80 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
cellular cation homeostasis GO:0030003 180 0.019
regulation of membrane potential GO:0042391 110 0.018
multi organism reproductive process GO:0044703 262 0.018
neurotransmitter biosynthetic process GO:0042136 2 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
amino acid betaine metabolic process GO:0006577 3 0.018
neuron death GO:0070997 127 0.018
androgen metabolic process GO:0008209 14 0.018
rhythmic process GO:0048511 156 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
protein processing GO:0016485 68 0.018
peptide transport GO:0015833 97 0.018
metal ion homeostasis GO:0055065 186 0.017
cellular response to peptide GO:1901653 133 0.017
signal release GO:0023061 145 0.017
regulation of peptide secretion GO:0002791 82 0.017
acetyl coa biosynthetic process from pyruvate GO:0006086 5 0.017
negative regulation of gene expression GO:0010629 199 0.017
regulation of cell proliferation GO:0042127 359 0.017
regulation of reactive oxygen species metabolic process GO:2000377 26 0.017
vesicle mediated transport GO:0016192 181 0.017
regulation of ion transport GO:0043269 245 0.017
macromolecule localization GO:0033036 252 0.016
development of primary sexual characteristics GO:0045137 107 0.016
reproductive structure development GO:0048608 128 0.016
anterior posterior pattern specification GO:0009952 1 0.016
response to glucocorticoid GO:0051384 223 0.016
proteolysis GO:0006508 175 0.016
negative regulation of cell death GO:0060548 229 0.016
regulation of signal transduction GO:0009966 318 0.015
response to biotic stimulus GO:0009607 226 0.015
synaptic transmission GO:0007268 235 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
carbohydrate metabolic process GO:0005975 130 0.015
regulation of insulin secretion GO:0050796 65 0.015
regulation of molecular function GO:0065009 398 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
response to estradiol GO:0032355 164 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
negative regulation of neuron death GO:1901215 69 0.015
negative regulation of signal transduction GO:0009968 83 0.015
hormone metabolic process GO:0042445 69 0.014
regulation of secretion by cell GO:1903530 208 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
mitochondrion organization GO:0007005 35 0.014
response to peptide GO:1901652 292 0.014
positive regulation of transport GO:0051050 245 0.014
amide transport GO:0042886 105 0.014
endocytosis GO:0006897 84 0.014
regulation of body fluid levels GO:0050878 90 0.014
monocarboxylic acid transport GO:0015718 52 0.013
metal ion transport GO:0030001 289 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
learning or memory GO:0007611 90 0.013
positive regulation of hemostasis GO:1900048 4 0.013
response to other organism GO:0051707 220 0.013
regulation of lipid biosynthetic process GO:0046890 38 0.013
organic acid biosynthetic process GO:0016053 83 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
regulation of cysteine type endopeptidase activity GO:2000116 32 0.013
regulation of neuron death GO:1901214 115 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
monosaccharide metabolic process GO:0005996 61 0.013
cellular polysaccharide biosynthetic process GO:0033692 15 0.013
glucose homeostasis GO:0042593 75 0.013
ossification GO:0001503 70 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
cdp choline pathway GO:0006657 3 0.013
negative regulation of developmental process GO:0051093 125 0.013
regulation of synaptic transmission GO:0050804 141 0.013
liver development GO:0001889 90 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
camera type eye development GO:0043010 48 0.012
developmental growth GO:0048589 100 0.012
neuron differentiation GO:0030182 368 0.012
response to peptide hormone GO:0043434 278 0.012
phospholipid metabolic process GO:0006644 61 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
organic hydroxy compound transport GO:0015850 77 0.012
response to hydrogen peroxide GO:0042542 89 0.012
phospholipid biosynthetic process GO:0008654 29 0.012
response to hexose GO:0009746 144 0.012
pyridine nucleotide metabolic process GO:0019362 28 0.012
circulatory system development GO:0072359 134 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.012
very long chain fatty acid metabolic process GO:0000038 3 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
cholesterol metabolic process GO:0008203 17 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
cellular component morphogenesis GO:0032989 155 0.012
pyridine containing compound metabolic process GO:0072524 32 0.012
female pregnancy GO:0007565 122 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
positive regulation of homeostatic process GO:0032846 49 0.012
sex differentiation GO:0007548 113 0.012
lipid transport GO:0006869 61 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
negative regulation of lipid biosynthetic process GO:0051055 2 0.011
gluconeogenesis GO:0006094 15 0.011
terpenoid metabolic process GO:0006721 37 0.011
protein phosphorylation GO:0006468 345 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
response to monosaccharide GO:0034284 159 0.011
regulation of protein processing GO:0070613 50 0.011
lipid storage GO:0019915 1 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
amino acid transport GO:0006865 70 0.011
neuron development GO:0048666 286 0.011
regulation of intracellular transport GO:0032386 65 0.011
endothelial cell apoptotic process GO:0072577 3 0.011
hepaticobiliary system development GO:0061008 90 0.011
regulation of response to tumor cell GO:0002834 3 0.011
ion homeostasis GO:0050801 212 0.011
multi multicellular organism process GO:0044706 138 0.011
cell redox homeostasis GO:0045454 1 0.011
cell projection organization GO:0030030 302 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.010
brain development GO:0007420 247 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
regulation of apoptotic signaling pathway GO:2001233 13 0.010
response to corticosteroid GO:0031960 235 0.010
succinate metabolic process GO:0006105 7 0.010
axon development GO:0061564 96 0.010

Hadhb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
disease of cellular proliferation DOID:14566 0 0.011
musculoskeletal system disease DOID:17 0 0.011