Rattus norvegicus

0 known processes

Eif4e2

eukaryotic translation initiation factor 4E family member 2

(Aliases: Eif4el3)

Eif4e2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.188
macromolecule localization GO:0033036 252 0.155
regulation of rna biosynthetic process GO:2001141 381 0.145
regulation of cellular component organization GO:0051128 368 0.139
transcription dna templated GO:0006351 377 0.134
regulation of rna metabolic process GO:0051252 391 0.131
guanosine containing compound metabolic process GO:1901068 74 0.120
regulation of phosphate metabolic process GO:0019220 349 0.112
positive regulation of phosphate metabolic process GO:0045937 262 0.110
rna metabolic process GO:0016070 406 0.109
negative regulation of macromolecule metabolic process GO:0010605 260 0.088
Fly
organelle organization GO:0006996 266 0.088
macromolecular complex assembly GO:0065003 273 0.076
regulation of nucleic acid templated transcription GO:1903506 380 0.076
protein complex assembly GO:0006461 263 0.075
catabolic process GO:0009056 351 0.074
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.073
transcription from rna polymerase ii promoter GO:0006366 252 0.072
aromatic compound catabolic process GO:0019439 168 0.071
positive regulation of nucleic acid templated transcription GO:1903508 197 0.070
nucleic acid templated transcription GO:0097659 379 0.067
macromolecular complex subunit organization GO:0043933 339 0.065
regulation of phosphorus metabolic process GO:0051174 349 0.065
cellular component biogenesis GO:0044085 368 0.064
negative regulation of metabolic process GO:0009892 331 0.062
Fly
biological adhesion GO:0022610 110 0.058
cytoskeleton organization GO:0007010 111 0.058
tissue development GO:0009888 252 0.058
intracellular signal transduction GO:0035556 314 0.057
negative regulation of cellular metabolic process GO:0031324 281 0.057
Fly
protein complex biogenesis GO:0070271 263 0.057
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.056
anatomical structure morphogenesis GO:0009653 298 0.053
Fly
regulation of transcription dna templated GO:0006355 374 0.052
cellular protein localization GO:0034613 122 0.052
heterocycle catabolic process GO:0046700 167 0.051
organic substance catabolic process GO:1901575 316 0.050
positive regulation of cellular component organization GO:0051130 200 0.049
cellular amino acid metabolic process GO:0006520 107 0.049
purine containing compound catabolic process GO:0072523 138 0.049
purine nucleoside triphosphate metabolic process GO:0009144 141 0.049
purine nucleotide metabolic process GO:0006163 229 0.048
negative regulation of gene expression GO:0010629 199 0.047
Fly
cellular response to stress GO:0033554 269 0.045
membrane organization GO:0061024 94 0.045
glycosyl compound metabolic process GO:1901657 182 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.044
Fly
guanosine containing compound catabolic process GO:1901069 71 0.044
purine nucleoside catabolic process GO:0006152 124 0.044
cell adhesion GO:0007155 110 0.044
response to inorganic substance GO:0010035 377 0.043
regulation of purine nucleotide metabolic process GO:1900542 115 0.043
protein complex subunit organization GO:0071822 302 0.043
gtp metabolic process GO:0046039 72 0.043
neuron projection development GO:0031175 273 0.042
nucleobase containing small molecule metabolic process GO:0055086 316 0.041
single organism catabolic process GO:0044712 283 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.040
response to peptide GO:1901652 292 0.040
nucleoside phosphate metabolic process GO:0006753 283 0.040
ribonucleoside metabolic process GO:0009119 174 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.039
neuron development GO:0048666 286 0.039
regulation of apoptotic process GO:0042981 335 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.038
organonitrogen compound catabolic process GO:1901565 179 0.038
nucleotide metabolic process GO:0009117 279 0.037
protein phosphorylation GO:0006468 345 0.037
apoptotic process GO:0006915 381 0.037
gtp catabolic process GO:0006184 71 0.036
neuron differentiation GO:0030182 368 0.036
cellular component assembly GO:0022607 360 0.036
oxoacid metabolic process GO:0043436 290 0.036
cellular macromolecule localization GO:0070727 122 0.036
positive regulation of biosynthetic process GO:0009891 319 0.036
positive regulation of cellular component biogenesis GO:0044089 55 0.035
aging GO:0007568 241 0.035
carbohydrate derivative catabolic process GO:1901136 147 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.034
Fly
purine containing compound metabolic process GO:0072521 253 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
regulation of protein metabolic process GO:0051246 289 0.034
Fly
regulation of cellular component biogenesis GO:0044087 86 0.032
organophosphate metabolic process GO:0019637 370 0.032
multi organism reproductive process GO:0044703 262 0.032
cellular nitrogen compound catabolic process GO:0044270 163 0.032
cell growth GO:0016049 104 0.031
nucleoside metabolic process GO:0009116 179 0.031
vesicle mediated transport GO:0016192 181 0.031
positive regulation of rna metabolic process GO:0051254 203 0.031
reproduction GO:0000003 245 0.030
regulation of organelle organization GO:0033043 80 0.029
cell projection organization GO:0030030 302 0.029
negative regulation of transcription dna templated GO:0045892 116 0.028
response to wounding GO:0009611 254 0.028
single organism organelle organization GO:1902589 180 0.028
establishment of protein localization GO:0045184 141 0.027
growth GO:0040007 165 0.027
cellular lipid metabolic process GO:0044255 208 0.027
response to hexose GO:0009746 144 0.027
developmental growth GO:0048589 100 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.026
negative regulation of biosynthetic process GO:0009890 168 0.026
Fly
reproductive process GO:0022414 372 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
cellular catabolic process GO:0044248 295 0.026
regulation of cell projection organization GO:0031344 175 0.026
purine ribonucleoside catabolic process GO:0046130 124 0.025
purine nucleoside triphosphate catabolic process GO:0009146 122 0.025
single organism intracellular transport GO:1902582 166 0.025
response to peptide hormone GO:0043434 278 0.025
small gtpase mediated signal transduction GO:0007264 36 0.024
ribonucleoside catabolic process GO:0042454 126 0.024
organic cyclic compound catabolic process GO:1901361 175 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
response to carbohydrate GO:0009743 183 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
negative regulation of rna metabolic process GO:0051253 123 0.024
negative regulation of protein metabolic process GO:0051248 114 0.024
Fly
ribonucleotide catabolic process GO:0009261 136 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
Fly
regulation of nucleotide metabolic process GO:0006140 117 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
proteolysis GO:0006508 175 0.023
purine ribonucleoside metabolic process GO:0046128 168 0.023
cell cell signaling GO:0007267 335 0.023
positive regulation of gene expression GO:0010628 244 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
amine metabolic process GO:0009308 38 0.022
single organism biosynthetic process GO:0044711 342 0.022
regulation of actin filament based process GO:0032970 42 0.022
positive regulation of nucleoside metabolic process GO:0045979 55 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.021
response to growth factor GO:0070848 189 0.021
locomotion GO:0040011 237 0.021
positive regulation of nucleotide metabolic process GO:0045981 91 0.021
heart morphogenesis GO:0003007 3 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
positive regulation of molecular function GO:0044093 230 0.020
regulation of purine nucleotide catabolic process GO:0033121 65 0.020
regulation of cell proliferation GO:0042127 359 0.020
cytokinetic process GO:0032506 1 0.020
lipid metabolic process GO:0006629 283 0.020
single organism cell adhesion GO:0098602 46 0.019
cellular amine metabolic process GO:0044106 38 0.019
nucleotide catabolic process GO:0009166 139 0.019
regulation of phosphorylation GO:0042325 248 0.019
purine nucleotide catabolic process GO:0006195 136 0.019
regulation of protein modification process GO:0031399 194 0.019
regulation of nucleoside metabolic process GO:0009118 66 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
positive regulation of developmental process GO:0051094 283 0.019
ribonucleoside triphosphate catabolic process GO:0009203 122 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
Fly
cell cycle GO:0007049 101 0.019
nitrogen compound transport GO:0071705 229 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
response to glucose GO:0009749 136 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
single organism cellular localization GO:1902580 102 0.018
regulation of transferase activity GO:0051338 123 0.018
regulation of neuron projection development GO:0010975 161 0.018
nucleoside catabolic process GO:0009164 126 0.018
nucleoside triphosphate catabolic process GO:0009143 123 0.018
regulation of catalytic activity GO:0050790 304 0.018
protein localization GO:0008104 191 0.018
single organism membrane organization GO:0044802 74 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
Fly
positive regulation of cell projection organization GO:0031346 111 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
cardiovascular system development GO:0072358 134 0.018
muscle structure development GO:0061061 87 0.018
positive regulation of cell communication GO:0010647 271 0.017
programmed cell death GO:0012501 392 0.017
organic acid metabolic process GO:0006082 292 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
regulation of cell differentiation GO:0045595 320 0.017
single organism reproductive process GO:0044702 297 0.017
regulation of anatomical structure size GO:0090066 135 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
lipid localization GO:0010876 62 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
regulation of cytoskeleton organization GO:0051493 49 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
regulation of neurogenesis GO:0050767 247 0.016
intracellular transport GO:0046907 185 0.016
rna localization GO:0006403 4 0.016
regulation of cell development GO:0060284 263 0.016
actin nucleation GO:0045010 2 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
protein transport GO:0015031 132 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
male gamete generation GO:0048232 99 0.015
connective tissue development GO:0061448 33 0.015
ras protein signal transduction GO:0007265 29 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
response to nutrient levels GO:0031667 370 0.015
response to monosaccharide GO:0034284 159 0.015
secretion GO:0046903 307 0.015
action potential GO:0001508 54 0.015
central nervous system development GO:0007417 311 0.015
cell part morphogenesis GO:0032990 123 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.014
cytoskeleton dependent cytokinesis GO:0061640 2 0.014
regulation of catabolic process GO:0009894 113 0.014
heart development GO:0007507 72 0.014
regulation of actin cytoskeleton organization GO:0032956 30 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
actin filament based process GO:0030029 86 0.014
carboxylic acid transport GO:0046942 115 0.014
cytoplasmic transport GO:0016482 115 0.014
regulation of protein kinase activity GO:0045859 105 0.014
brain development GO:0007420 247 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
head development GO:0060322 247 0.014
regulation of signal transduction GO:0009966 318 0.014
anion transport GO:0006820 178 0.013
wound healing GO:0042060 122 0.013
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
gland development GO:0048732 155 0.013
cellular component morphogenesis GO:0032989 155 0.013
organic anion transport GO:0015711 132 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
regulation of cell cycle GO:0051726 73 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
positive regulation of cell death GO:0010942 184 0.013
localization of cell GO:0051674 202 0.013
regulation of membrane potential GO:0042391 110 0.013
regulation of nucleotide catabolic process GO:0030811 65 0.013
protein oligomerization GO:0051259 191 0.013
neuron projection morphogenesis GO:0048812 122 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
positive regulation of catabolic process GO:0009896 78 0.012
negative regulation of cell communication GO:0010648 158 0.012
regulation of molecular function GO:0065009 398 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
circulatory system process GO:0003013 183 0.012
protein polymerization GO:0051258 22 0.012
synaptic transmission GO:0007268 235 0.012
cellular ketone metabolic process GO:0042180 51 0.012
cell type specific apoptotic process GO:0097285 134 0.012
blood circulation GO:0008015 183 0.012
lipid storage GO:0019915 1 0.012
regulation of kinase activity GO:0043549 117 0.012
ion transmembrane transport GO:0034220 365 0.012
anterior posterior pattern specification GO:0009952 1 0.012
positive regulation of nucleotide catabolic process GO:0030813 53 0.012
positive regulation of cell development GO:0010720 176 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
endoplasmic reticulum organization GO:0007029 1 0.012
negative regulation of translational initiation GO:0045947 5 0.012
striated muscle tissue development GO:0014706 58 0.012
secretion by cell GO:0032940 248 0.012
immune system process GO:0002376 204 0.012
actin cytoskeleton organization GO:0030036 73 0.012
cellular macromolecular complex assembly GO:0034622 58 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
regulation of translation GO:0006417 27 0.011
Fly
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of growth GO:0040008 105 0.011
chemical homeostasis GO:0048878 292 0.011
response to extracellular stimulus GO:0009991 380 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
translation GO:0006412 35 0.011
Fly
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.011
multicellular organism reproduction GO:0032504 233 0.011
spermatogenesis GO:0007283 99 0.011
extracellular matrix constituent secretion GO:0070278 4 0.011
nuclear transport GO:0051169 49 0.011
multicellular organismal signaling GO:0035637 44 0.011
regulation of programmed cell death GO:0043067 341 0.011
negative regulation of arp2 3 complex mediated actin nucleation GO:0034316 1 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
cell migration GO:0016477 197 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.010
regulation of protein complex assembly GO:0043254 33 0.010
axis specification GO:0009798 4 0.010
cellular response to oxygen containing compound GO:1901701 386 0.010
developmental process involved in reproduction GO:0003006 159 0.010
regulation of gtp catabolic process GO:0033124 58 0.010
positive regulation of protein modification process GO:0031401 142 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
chromosome segregation GO:0007059 2 0.010

Eif4e2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014